AcuTrials

Effect of electroacupuncture at Zusanli (ST36) and Sanyinjiao (SP6) acupoints on adrenocortical function in etomidate anesthesia patients

Item

Title

Effect of electroacupuncture at Zusanli (ST36) and Sanyinjiao (SP6) acupoints on adrenocortical function in etomidate anesthesia patients

Journal Publication

Medical science monitor : international medical journal of experimental and clinical research

Date

2014

volume

20

pages

406-412

Research Type

RCT

Keywords

Anesthesia and Analgesia
Adrenal Cortical Inhibition
Acu + Usual Care Versus > 1 Control
Electroacupuncture
TCM Acupuncture Style
Fixed Acupuncture Protocol
Restricted Modalities, Acupuncture Only
Usual Care Control, Pharmaceutical
Standard Needling Depth
Sham Acupoint Control
Adrenocortical Function
Glucocorticoid Secretion

Abstract

Background We aimed to investigate the effect of electroacupuncture at Zusanli (ST36) and Sanyinjiao (SP6) on adrenocortical function in patients with etomidate anesthesia. Material and Methods We randomly divided 80 patients who underwent elective surgery into 4 groups: group etomidate (ETO), group etomidate + electroacupuncture (ETO+EA), group etomidate + sham acupuncture (ETO+SEA), and group propofol (PRO). The patients in group ETO, ETO+EA, and ETO+SEA were induced with etomidate and sufentanil and maintained with intravenous infusion of etomidate and remifentanil. Group PRO was induced with propofol and sufentanil and maintained with propofol and remifentanil. Group ETO+EA received electro-acupuncture stimulation at Zusanli and Sanyinjiao throughout the operation, while group ETO+SEA received electro-acupuncture stimulation at non-acupoints. We recorded the values of MAP, HR, BIS, CVP, cortisol, ACTH, epinephrine, norepinephrine, and arterial blood gas during the perioperative period. Results Cortisol concentrations were significantly higher at all times except T0 in group ETO+EA compared with group ETO. The ACTH concentrations were lower in group ETO+EA than that in group ETO at point T3. Conclusions Electroacupuncture at ST 36 and SP 6 can mitigate the adrenal cortical inhibition induced by etomidate and can reduce the secretion of catecholamines during surgery.

doi

10.12659/MSM.890111

Time in Treatment

1 Day

has health condition studied

Anesthesia and Analgesia

has study population number

80

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