Electroacupuncture for Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials

Liu, A.-J.

Li, J.-H.

Li, H.-Q.

Fu, D.-L.

Lu, L.

Bian, Z.-X.

Zheng, G.-Q.

American Journal of Chinese Medicine

2015

43(8)

1541-1566

Systematic Review

CHI-squared test

CONFIDENCE intervals

Electroacupuncture

INFORMATION storage & retrieval systems -- Medical care

INFORMATION storage & retrieval systems -- Medicine

Medline

META-analysis

ONLINE information services

PATIENTS -- Safety measures

RESEARCH -- Finance

SYSTEMATIC reviews (Medical research)

RANDOMIZED controlled trials

TREATMENT effectiveness

DATA analysis -- Software

STROKE -- Patients -- Rehabilitation

DESCRIPTIVE statistics

AMED (Information retrieval system)

Electroacupuncture (EA) is an extension technique of acupuncture based on traditional acupuncture combined with modern electrotherapy. Here, we conducted a systematic review specifically to assess the effectiveness and safety of EA for acute ischemic stroke. Eight databases were searched for randomized-controlled clinical trials (RCTs) of EA for acute ischemic stroke published from inception to June 2013. Ultimately, 67 studies claimed to be RCTs. Eighteen studies with 1411 individuals were selected for the analyses, which got 'yes' in the domains of Cochrane risk of bias tool. The meta-analysis showed a significant effect of EA for improving Barthel Index (), Fugl-Meyer Assessment (), National Institutes of Health Stroke Scale () and Revised Scandinavian Stroke Scale () compared with western conventional treatments (WCTs). In an analysis of the total clinical efficacy rate, there was a significant difference between EA and WCTs (). Adverse effects were monitored in 6 studies, and were well tolerated in all stroke patients. According to the GRADE approach, the quality of evidence was mostly high or moderate. In conclusion, this systematic review revealed the evidence in support of the use of EA for acute ischemic stroke, although further larger sample-size and rigorously designed RCTs are required.

Accession Number: 112083268; Source Information: 2015, Vol. 43 Issue 8, p1541; Subject Term: CHI-squared test; Subject Term: CONFIDENCE intervals; Subject Term: ELECTROACUPUNCTURE; Subject Term: INFORMATION storage & retrieval systems -- Medical care; Subject Term: INFORMATION storage & retrieval systems -- Medicine; Subject Term: MEDLINE; Subject Term: META-analysis; Subject Term: ONLINE information services; Subject Term: PATIENTS -- Safety measures; Subject Term: RESEARCH -- Finance; Subject Term: SYSTEMATIC reviews (Medical research); Subject Term: RANDOMIZED controlled trials; Subject Term: TREATMENT effectiveness; Subject Term: DATA analysis -- Software; Subject Term: STROKE -- Patients -- Rehabilitation; Subject Term: DESCRIPTIVE statistics; Subject Term: AMED (Information retrieval system); Subject Term: ; Number of Pages: 26p; ; Illustrations: 1 Diagram, 10 Charts, 1 Graph; ; Document Type: Article;

0