AcuTrials

Lifestyle-Related Factors in the Self-Management of Chemotherapy-Induced Peripheral Neuropathy in Colorectal Cancer: A Systematic Review

Item

Title

Lifestyle-Related Factors in the Self-Management of Chemotherapy-Induced Peripheral Neuropathy in Colorectal Cancer: A Systematic Review

Journal Publication

Evidence-based Complementary & Alternative Medicine (eCAM)

Date

2017

Research Type

Systematic Review

Keywords

ALTERNATIVE medicine
ANTINEOPLASTIC agents
DIETARY supplements
INFORMATION storage & retrieval systems -- Medicine
PERIPHERAL neuropathy
ONLINE information services
SYSTEMATIC reviews (Medical research)

Abstract

Background. Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect of chemotherapy treatment in colorectal cancer (CRC), negatively affecting the daily functioning and quality of life of CRC patients. Currently, there are no established treatments to prevent or reduce CIPN. The purpose of this systematic review was to identify lifestyle-related factors that can aid in preventing or reducing CIPN, as such factors may promote self-management options for CRC patients suffering from CIPN. Methods. A literature search was conducted through PubMed, Embase, and Google Scholar. Original research articles investigating oxaliplatin-related CIPN in CRC were eligible for inclusion. Results. In total, 22 articles were included, which suggested that dietary supplements, such as antioxidants and herbal extracts, as well as physical exercise and complementary therapies, such as acupuncture, may have beneficial effects on preventing or reducing CIPN symptoms. However, many of the reviewed articles presented various limitations, including small sample sizes and heterogeneity in study design and measurements of CIPN. Conclusions. No strong conclusions can be drawn regarding the role of lifestyle-related factors in the management of CIPN in CRC patients. Certain dietary supplements and physical exercise may be beneficial for the management of CIPN, but further research is warranted.

pmid

Accession Number: 121885369; Source Information: 3/16/2017, p1; Subject Term: ALTERNATIVE medicine; Subject Term: ANTINEOPLASTIC agents; Subject Term: COLON tumors; Subject Term: DIETARY supplements; Subject Term: EXERCISE; Subject Term: INFORMATION storage & retrieval systems -- Medicine; Subject Term: MEDLINE; Subject Term: PERIPHERAL neuropathy; Subject Term: ONLINE information services; Subject Term: QUALITY of life; Subject Term: RECTUM -- Tumors; Subject Term: HEALTH self-care; Subject Term: SYSTEMATIC reviews (Medical research); Subject Term: OXALIPLATIN; Subject Term: LIFESTYLES; Subject Term: ; Number of Pages: 14p; ; Illustrations: 1 Diagram, 1 Chart; ; Document Type: Article;

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