Pattern Differentiation of Lateral Elbow Pain in Traditional Chinese Medicine: A Systematic Review
Item
Title
Pattern Differentiation of Lateral Elbow Pain in Traditional Chinese Medicine: A Systematic Review
Journal Publication
Date
2016
volume
22(11)
pages
921-935
Research Type
RCT
Keywords
Abstract
Previous studies have demonstrated that acupuncture is beneficial to patients with Crohn’s disease (CD), but the mechanism underlying its therapeutic effects remains unclear. To identify the mechanism by which acupuncture treats CD, the balance between Th17 and Treg cells was assessed in CD patients. In this study, Ninety-two CD patients were randomly and equally assigned to a treatment group that were treated with herb-partitioned moxibustion and acupuncture or a control group with wheat bran-partitioned moxibustion and superficial acupuncture. The effect of these treatments on Th17 and Treg cells and their related molecular markers in the intestinal mucosa were detected before (week 0) and after (week 12) treatment. The results suggested that the ratio of Th17 and Treg cells was significantly decreased after treatment and that the levels of IL-17 and ROR?t in the intestinal mucosa were obviously reduced, while the expression of FOXP3 was increased after treatment in both groups. In the treatment group, the expression of these molecules was more markedly regulated than the control group. In conclusion, moxibustion and acupuncture have been shown to regulate the ratio of Th17 and Treg cells in the intestinal mucosa of CD patients and restore the balance between these immune cell subsets.
pmid
Accession Number: 119498026; Source Information: Nov2016, Vol. 22 Issue 11, p921; Subject Term: TENNIS elbow -- Treatment; Subject Term: INFORMATION storage & retrieval systems -- Medical care; Subject Term: INFORMATION storage & retrieval systems -- Medicine; Subject Term: CHINESE medicine; Subject Term: MEDLINE; Subject Term: ONLINE information services; Subject Term: RESEARCH -- Finance; Subject Term: TENNIS elbow; Subject Term: TEXTBOOKS; Subject Term: SYSTEMATIC reviews (Medical research); Subject Term: EVIDENCE-based medicine; Subject Term: PROFESSIONAL practice; Subject Term: AMED (Information retrieval system); Subject Term: SYMPTOMS; Subject Term: ; Number of Pages: 15p; ; Document Type: Article;
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