AcuTrials

Traditional Chinese medicine for schizophrenia: A survey of randomized trials

Item

Title

Traditional Chinese medicine for schizophrenia: A survey of randomized trials

Journal Publication

Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists

Date

2017

volume

9(1)

Research Type

Systematic Review

Keywords

Abstract

OBJECTIVE: To survey the reports of randomized trials of traditional Chinese medicine (TCM) interventions for schizophrenia and produce a broad overview of this type of research activity in this area. METHOD: We searched the Cochrane Schizophrenia Group's comprehensive Trials Register (January 2016), selected all relevant randomized trials, and extracted the data within each study. Finally, we sought relevant reviews on the Cochrane Library. RESULTS: We initially screened 423 articles from which we identified 378 relevant studies randomizing 35 341 participants (average study size 94, SD 60). There were 7 herbs used as single medicine, 4 compositions or extractions, more than 144 herbal mixes, and 7 TCM principles reported for schizophrenia. Nonpharmacological interventions of TCM included acupuncture and exercise. The most commonly evaluated treatments are Ginkgo biloba, acupuncture, Wendan decoction, and Shugan Jieyu Capsule. There are 3 directly relevant Cochrane reviews. CONCLUSIONS: Most treatment approaches-and some in common use-have only one or two relevant small trials. Some coordination of effort would help ensure that further well-designed appropriately sized randomized trials are conducted. Systematic reviews should be performed in this field but with titles that take into account the complexity of TCM.

doi

10.1111/appy.12265

pmid

PMID:27734592

Language

English

has health condition studied

Mental Disorders

has study population number

0

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