AcuTrials

Acupuncture for Pain and Dysfunction After Neck Dissection: Results of a Randomized Controlled Trial

Item

Title

Acupuncture for Pain and Dysfunction After Neck Dissection: Results of a Randomized Controlled Trial

Journal Publication

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Date

2010

Research Type

RCT

Keywords

Acu + Usual Care Versus Usual Care
TCM Acupuncture Style
Semi-Individualized Acupuncture Protocol
Symptom Based Point Selection
Restricted Modalities, Acupuncture Only
Usual Care Control, Multimodality

Abstract

PURPOSE: To determine whether acupuncture reduces pain and dysfunction in patients with cancer with a history of neck dissection. The secondary objective is to determine whether acupuncture relieves dry mouth in this population. PATIENTS AND METHODS: Patients at a tertiary cancer center with chronic pain or dysfunction attributed to neck dissection were randomly assigned to weekly acupuncture versus usual care (eg, physical therapy, analgesia, and/or anti-inflammatory drugs, per patient preference or physician recommendation) for 4 weeks. The Constant-Murley score, a composite measure of pain, function, and activities of daily living, was the primary outcome measure. Xerostomia, a secondary end point, was assessed using the Xerostomia Inventory. RESULTS: Fifty-eight evaluable patients were accrued and randomly assigned from 2004 to 2007 (28 and 30 patients on acupuncture and control arms, respectively). Constant-Murley scores improved more in the acupuncture group (adjusted difference between groups = 11.2; 95% CI, 3.0 to 19.3; P = .008). Acupuncture produced greater improvement in reported xerostomia (adjusted difference in Xerostomia Inventory = -5.8; 95% CI, -0.9 to -10.7; P = .02). CONCLUSION: Significant reductions in pain, dysfunction, and xerostomia were observed in patients receiving acupuncture versus usual care. Although further study is needed, these data support the potential role of acupuncture in addressing post-neck dissection pain and dysfunction, as well as xerostomia.

Frequency of Treatment

1/WK

Time in Treatment

4 Weeks

has health condition studied

Neoplasms

has study population number

58

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