Acupuncture for vascular mild cognitive impairment: a systematic review of randomised controlled trials

Item

Title

Acupuncture for vascular mild cognitive impairment: a systematic review of randomised controlled trials

Author(s)

Journal Publication

Date

2013

pages

368-374

Research Type

Systematic Review

Keywords

Abstract

BACKGROUND: Vascular mild cognitive impairment (VMCI) is the most common type of vascular cognitive impairment induced by cerebrovascular disease. No effective medicines are currently available for VMCI. OBJECTIVE: To assess the effectiveness and safety of acupuncture for VMCI. METHODS: Seven electronic databases were searched for randomised controlled trials which investigated the effects of acupuncture compared with no treatment, placebo or conventional therapies on cognitive function or other clinical outcomes in patients with VMCI. The quality of the trials selected was evaluated according to the 'risk of bias' assessment provided by the Cochrane Handbook for Systematic Reviews of Interventions. RevMan V.5.1 software was employed for data analysis. RESULTS: Twelve trials with 691 participants were included. The methodological quality of all included trials was unclear and/or they had a high risk of bias. Meta-analysis showed acupuncture in conjunction with other therapies could significantly improve Mini-Mental State Examination scores (mean difference 1.99, 95% CI 1.09 to 2.88, random model, p<0.0001, 6 trials). No included trials mentioned any adverse events of the treatment. CONCLUSIONS: The current clinical evidence is not of sufficient quality for wider application of acupuncture to be recommended for the treatment of VMCI, and further large, rigorously designed trials are warranted.

pmid

Date of Input: 11/7/2013; Date Modified: 6/3/2014; Availability: --In File--; Priority: Normal; Mild Cognitive Impairment; Professor Jianping Liu, Centre for Evidence-Based Chinese Medicine, University of Chinese Medicine, Bei San Huan Dong Lu 11, Chaoyang District, Beijing 100029, China; email: jianping_I@hotmail.com; Eng; Web: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=24123487

Time in Treatment

31

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