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Author Zhang, Y.; Qu, S.-shan; Zhang, J.-ping; Sun, Y.-ling; Liu, W.-lu; Xie, L.; Huang, Y.; Chen, J.-qi url  openurl
  Title Rapid Onset of the Effects of Combined Selective Serotonin Reuptake Inhibitors and Electroacupuncture on Primary Depression: A Meta-Analysis Type of Study Journal Article
  Year 2016 Publication Journal of Alternative & Complementary Medicine Abbreviated Journal Journal of Alternative & Complementary Medicine  
  Volume 22 Issue 1 Pages 1-8  
  Keywords MENTAL depression -- Treatment; SEROTONIN uptake inhibitors -- Therapeutic use; RESEARCH methodology evaluation; ALTERNATIVE medicine; COMBINED modality therapy; CONFIDENCE intervals; Electroacupuncture; EXPERIMENTAL design; HAMILTON Depression Inventory; INFORMATION storage & retrieval systems -- Medical care; Medline; META-analysis; ONLINE information services; PROBABILITY theory; PSYCHOLOGICAL tests; SEROTONIN uptake inhibitors; SYSTEMATIC reviews (Medical research); EVIDENCE-based medicine; PROFESSIONAL practice; RANDOMIZED controlled trials; TREATMENT effectiveness; DATA analysis -- Software; MEDICAL coding; DESCRIPTIVE statistics; Evaluation; China  
  Abstract Objectives: To evaluate the efficacy and safety of combined selective serotonin reuptake inhibitors (SSRIs) and electroacupuncture therapies for the early treatment of primary depression. Methods: Randomized controlled trials (RCTs) were analyzed to compare therapy combining SSRIs and electroacupuncture to SSRI therapy alone. The RCTs were identified by searching, among others, PubMed, the Cochrane Library, the Chinese National Knowledge Infrastructure, the Chongqing VIP database for Chinese Technical Periodicals, WANFANG DATA, and the Chinese Biological Medical Literature Database. Scores from Self-Rated Depression Scale (SDS), the Hamilton Depression Scale (HAMD), the Side Effect Rating Scale (SERS), and the Treatment Emergent Symptom Scale (TESS) were analyzed and coded by two independent investigators and used to evaluate the safety and efficacy of treatment. Statistical analyses were performed using RevMan 5.2 software. Results: Six RCTs were analyzed. The meta-analysis revealed that the combined therapy of SSRIs and electroacupuncture were associated with superior scores on the HAMD, SDS, and SERS measures compared with SSRIs alone after 1-4 weeks of treatment: HAMD scores, mean difference (MD)1 week, 2.32 (95% confidence interval [CI]1 week, 1.47-3.16, p1 week<0.00001); MD2 weeks, 2.65 (95% CI2 weeks, 1.81- 3.50, p2 weeks<0.00001); MD4 weeks, 2.70 (95% CI4 weeks, 1.90-3.51, p4 weeks<0.00001); SDS scores: MD1 week, 3.13 (95% CI1 week, 1.22-5.03, p1 week = 0.001); MD2 weeks, 4.05 (95% CI2 weeks, 0.22-7.87, p2 weeks = 0.04); MD4 weeks, 5.02 (95% CI4 weeks, 1.61-8.43, p4 weeks = 0.004); SERS scores: MD2 weeks, 2.20 (95% CI2 weeks, 1.43-2.96, p2 weeks<0.00001); MD4 weeks, 2.12 (95% CI4 weeks, 1.42-2.83, p4 weeks<0.00001). However, two of the aforementioned outcomes were rated as medium quality because of heterogeneity, as assessed using the Grading of Recommendations Assessment, Development and Evaluation system. Conclusions: The available evidence suggests that the early treatment of primary depression using both SSRI and electroacupuncture therapies is more efficient than treatments with SSRIs alone and leads to a better and earlier control of depressive symptoms.  
  Address  
  Publisher Mary Ann Liebert, Inc.
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 112335762; Source Information: Jan2016, Vol. 22 Issue 1, p1; Subject Term: MENTAL depression -- Treatment; Subject Term: SEROTONIN uptake inhibitors -- Therapeutic use; Subject Term: RESEARCH methodology evaluation; Subject Term: ALTERNATIVE medicine; Subject Term: COMBINED modality therapy; Subject Term: CONFIDENCE intervals; Subject Term: ELECTROACUPUNCTURE; Subject Term: EXPERIMENTAL design; Subject Term: HAMILTON Depression Inventory; Subject Term: INFORMATION storage & retrieval systems -- Medical care; Subject Term: MEDLINE; Subject Term: META-analysis; Subject Term: ONLINE information services; Subject Term: PROBABILITY theory; Subject Term: PSYCHOLOGICAL tests; Subject Term: SEROTONIN uptake inhibitors; Subject Term: SYSTEMATIC reviews (Medical research); Subject Term: EVIDENCE-based medicine; Subject Term: PROFESSIONAL practice; Subject Term: RANDOMIZED controlled trials; Subject Term: TREATMENT effectiveness; Subject Term: DATA analysis -- Software; Subject Term: MEDICAL coding; Subject Term: DESCRIPTIVE statistics; Subject Term: EVALUATION; Subject Term: ; Geographic Subject: CHINA; Geographic Subject: ; Number of Pages: 8p; ; Illustrations: 1 Diagram, 11 Charts; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2241  
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Author Zheng, Y.; Zhang, J.; Wang, Y.; Wang, Y.; Lan, Y.; Qu, S.; Tang, C.; Huang, Y. url  doi
openurl 
  Title Acupuncture Decreases Blood Pressure Related to Hypothalamus Functional Connectivity with Frontal Lobe, Cerebellum, and Insula: A Study of Instantaneous and Short-Term Acupuncture Treatment in Essential Hypertension Type of Study Journal Article
  Year 2016 Publication Evidence-Based Complementary and Alternative Medicine : ECAM Abbreviated Journal Evid Based Complement Alternat Med  
  Volume 2016 Issue Pages 6908710  
  Keywords  
  Abstract The therapeutic effects of acupuncture in decreasing blood pressure are ambiguous and underlying acupuncture in hypertension treatment has not been investigated. Our objective was to observe the change of quality of life and compare the differences in brain functional connectivity by investigating instantaneous and short-term acupuncture treatment in essential hypertension patients. A total of 30 patients were randomly divided into the LR3 group and sham acupoint group. Subjects received resting-state fMRI among preacupuncture, postinstantaneous, and short-term acupuncture treatment in two groups. Hypothalamus was selected as the seed point to analyze the changes in connectivity. We found three kinds of results: (1) There was statistical difference in systolic blood pressure in LR3 group after the short-term treatment and before acupuncture. (2) Compared with sham acupoint, acupuncture at LR3 instantaneous effects in the functional connectivity with seed points was more concentrated in the frontal lobe. (3) Compared with instantaneous effects, acupuncture LR3 short-term effects in the functional connectivity with seed points had more regions in frontal lobe, cerebellum, and insula. These brain areas constituted a neural network structure with specific functions that could explain the mechanism of therapy in hypertension patients by LR3 acupoint.  
  Address School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:27688791; PMCID:PMC5027048 Approved no  
  Call Number OCOM @ refbase @ Serial 2147  
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Author Ching, NG Kwok; Liu, Y.; Lee, K.; Huang, Y.; Qu, S. openurl 
  Title A Clinical Observation on Treating Migraine by the Combination of Scalp Acupuncture and Craniosacral Therapy Type of Study RCT
  Year 2010 Publication International Journal of Clinical Acupuncture Abbreviated Journal Int J Clin Acupunct  
  Volume 19 Issue 4 Pages 161-164  
  Keywords Headache Disorders; Migraine; Scalp Acupuncture; AcuTrials; RCT; Acu Versus Acu; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture + Other; Acu Versus CAM Control; Craniosacral Therapy  
  Abstract  
  Address  
  Publisher
  Language Number of Treatments 8  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants 62  
  Time in Treatment 4 Weeks Condition Migraine
  Disease Category Headache Disorders OCSI Score  
  Notes Approved no  
  Call Number Serial 170  
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Author Qu, S. S.; Huang, Y.; Zhang, Z. J.; Chen, J. Q.; Lin, R. Y.; Wang, C. Q.; Li, G. L.; Wong, H. K.; Zhao, C. H.; Pan, J. Y.; Guo, S. C.; Zhang, Y. C. url  doi
openurl 
  Title A 6-week randomized controlled trial with 4-week follow-up of acupuncture combined with paroxetine in patients with major depressive disorder Type of Study RCT
  Year 2013 Publication Journal of psychiatric research Abbreviated Journal J Psychiatr Res  
  Volume 47 Issue 6 Pages 726-732  
  Keywords AcuTrials; RCT; Mental Disorders; Depressive Disorder, Major; Depression; Acu Versus > 1 Control; Acu Versus Acu; Acu + Usual Care Versus Usual Care; Electroacupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; CAM Control; Usual Care Control, Pharmaceutical; Mental Illness  
  Abstract Acupuncture possesses the antidepressant potential. In this 6-week randomized controlled trial with 4-week follow-up, 160 patients with major depressive disorder (MDD) were randomly assigned to paroxetine (PRX) alone (n = 48) or combined with 18 sessions of manual acupuncture (MA, n = 54) or electrical acupuncture (EA, n = 58). Treatment outcomes were measured mainly using the 17-item Hamilton Depression Rating Scale (HAMD-17), Self-rating Depression Scale (SDS), clinical response and remission rates. Average PRX dose taken and proportion of patients who required an increased PRX dose due to symptom aggravation were also obtained. Both additional MA and EA produced a significantly greater reduction from baseline in score on HAMD-17 and SDS at most measure points from week 1 through week 6 compared to PRX alone. The clinical response was markedly greater in MA (69.8%) and EA (69.6%) groups than the group treated with PRX alone (41.7%, P = 0.004). The proportion of patients who required an increase dose of PRX due to symptom aggravation was significantly lower with MA (5.7%) and EA (8.9%) than PRX alone (22.9%, P = 0.019). At 4 weeks follow-up after completion of acupuncture treatment, patients with EA, but not MA, continued to show significantly greater clinical improvement. Incidence of adverse events was not different in the three groups. Our study indicates that acupuncture can accelerate the clinical response to selective serotonin reuptake inhibitors (SSRIs) and prevent the aggravation of depression. Electrical acupuncture may have a long-lasting enhancement of the antidepressant effects (Trial Registration: ChiCTR-TRC-08000278).  
  Address School of Traditional Chinese Medicine, Southern Medical University, 1023 Shatai Road, Guangzhou, Guangdong 510515, China.  
  Publisher
  Language Number of Treatments 18  
  Treatment Follow-up 4 Weeks Frequency >1/WK Number of Participants 160  
  Time in Treatment 6 Weeks Condition Depressive Disorder, Major
  Disease Category Mental Disorders OCSI Score  
  Notes Approved no  
  Call Number Serial 966  
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Author Huang, Y.; Tang, C.; Wang, S.; Lu, Y.; Shen, W.; Yang, J.; Chen, J.; Lin, R.; Cui, S.; Xiao, H.; Qu, S.; Lai, X.; Shan, B. url  openurl
  Title Acupuncture regulates the glucose metabolism in cerebral functional regions in chronic stage ischemic stroke patients----a PET-CT cerebral functional imaging study Type of Study RCT
  Year 2012 Publication BMC neuroscience Abbreviated Journal BMC Neurosci  
  Volume 13 Issue 1 Pages 75-  
  Keywords AcuTrials; RCT; Stroke; Acu Versus > 1 Control; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Sham Control; Non Penetrating Sham, Mechanical; Verum Acupoint Control; Penetrating Sham; Standard Needling Depth; Sham Acupoint Control;  
  Abstract ABSTRACT: BACKGROUND: Acupuncture has been applied to aid in the recovery of post-stroke patients, but its mechanism is unclear. This study aims to analyze the relationship between acupuncture and glucose metabolism in cerebral functional regions in post-stroke patients using 18 FDG PETCT techniques. Forty-three ischemic stroke patients were randomly divided into 5 groups: the Waiguan (TE5) needling group, the TE5 sham needling group, the sham point needling group, the sham point sham needling group and the non-needling group. Cerebral functional images of all patients were then acquired using PET-CT scans and processed by SPM2 software. RESULTS: Compared with the non-needling group, sham needling at TE5 and needling/sham needling at the sham point did not activate cerebral areas. However, needling at TE5 resulted in the activation of Brodmann Area (BA) 30. Needling/sham needling at TE5 and needling at the sham point did not deactivate any cerebral areas, whereas sham needling at the sham point led to deactivation in BA6. Compared with sham needling at TE5, needling at TE5 activated BA13, 19 and 47 and did not deactivate any areas. Compared with needling at the sham point, needling at TE5 had no associated activation but a deactivating effect on BA9. CONCLUSION: Needling at TE5 had a regulating effect on cerebral functional areas shown by PET-CT, and this may relate to its impact on the recovery of post-stroke patients.  
  Address Department of Acupuncture and Massage, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China. Email: lai1023@163.com  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up N/A Frequency N/A Number of Participants 43  
  Time in Treatment 1 Day Condition Stroke
  Disease Category Stroke OCSI Score  
  Notes Approved no  
  Call Number Serial 485  
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