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Author Huanqin Li; Huilin Liu; Cunzhi Liu; Guangxia Shi; Wei Zhou; Chengmei Zhao; Tao Zhang; Xuefei Wang; Guiling Wang; Yin Zhao; Jingqing Sun; Jing Wang; Linpeng Wang url  openurl
  Title Effect of 'Deqi' during the Study of Needling 'Wang's Jiaji' Acupoints Treating Spasticity after Stroke Type of Study Journal Article
  Year 2014 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evid Based Complement Altern Med  
  Volume 2014 Issue Pages 1-8  
  Keywords Muscle Spasticity -- Drug Therapy; Acupuncture Points; Stroke -- Therapy; Stroke -- Symptoms; Acupuncture -- Evaluation; Sensation -- Evaluation; Human; Multicenter Studies; Prospective Studies; Randomized Controlled Trials; Single-Blind Studies; Adult; Middle Age; Aged; Aged, 80 and Over; Glasgow Coma Scale; Scales; NIH Stroke Scale; Tomography, X-Ray Computed; Magnetic Resonance Imaging; Outcomes Research; Outcome Assessment; Barthel Index; Chi Square Test; Nonparametric Statistics; Fisher's Exact Test; Data Analysis Software; Two-Tailed Test  
  Abstract  
  Address Traditional Chinese Medicine Department, Fangshan Hospital of Traditional Chinese Medicine, 151 Chengguan South Street, Fangshan District, Beijing 102400, China  
  Publisher Hindawi Limited
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 103876776. Language: English. Entry Date: 20150130. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice; Gerontologic Care. Instrumentation: NIH Stroke Scale; Activities of Daily Living (ADL) Scale; Fugl-Meyer Assessment (FMA); Barthel Index; Stroke-Specific Quality of Life scale (SSQOL); Rankin Scale; Glasgow Coma Scale (GCS). NLM UID: 101215021. Approved no  
  Call Number OCOM @ refbase @ 103876776 Serial 2399  
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Author Hyun-jong Lee; Jung-chul Seo; Sung-hoon Park; Min-ah Kwak; Im hee Shin; Bo-mi Min; Min-su Cho; Woon-seok Roh; Jin-yong Jung url  doi
openurl 
  Title Acupuncture in Patients with a Vertebral Compression Fracture: A Protocol for a Randomized, Controlled, Pilot Clinical Trial Type of Study Journal Article
  Year 2015 Publication Journal of Pharmacopuncture Abbreviated Journal J Pharmacopuncture  
  Volume 18 Issue 1 Pages 79-85  
  Keywords Acupuncture; Fractures, Vertebral Compression; Steroids -- Administration and Dosage; Injections, Epidural; Human; Randomized Controlled Trials; Protocols; Pilot Studies; McGill Pain Questionnaire; Magnetic Resonance Imaging; Visual Analog Scaling; Questionnaires; Data Analysis Software; Funding Source  
  Abstract  
  Address Department of Anesthesiology and Pain Medicine, School of Medicine, Catholic University, Daegu, Korea  
  Publisher Korean Pharmacopuncture Institute
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 103790494. Language: English. Entry Date: 20150421. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Alternative/Complementary Therapies; Asia. Instrumentation: McGill Pain Questionnaire. Grant Information: This study was supported by a grant from the Ministry of Health & Welfare, Korea, 2013.. NLM UID: 101572812. Approved no  
  Call Number OCOM @ refbase @ 103790494 Serial 2324  
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Author Jiping Zhang; Yu Zheng; Yanjie Wang; Shanshan Qu; Shaoqun Zhang; Chunxiao Wu; Junqi Chen; Huailiang Ouyang; Chunzhi Tang; Yong Huang url  openurl
  Title Evidence of a Synergistic Effect of Acupoint Combination: A Resting-State Functional Magnetic Resonance Imaging Study Type of Study Journal Article
  Year 2016 Publication Journal of Alternative & Complementary Medicine Abbreviated Journal Journal of Alternative & Complementary Medicine  
  Volume 22 Issue 10 Pages 800-809  
  Keywords BRAIN -- Physiology; CEREBELLUM -- Physiology; CEREBRAL cortex -- Physiology; Acupuncture; ACUPUNCTURE points; ALTERNATIVE medicine; MAGNETIC resonance imaging; PROBABILITY theory; RESEARCH -- Finance; SAMPLING (Statistics); Statistics; T-test (Statistics); DATA analysis; BODY mass index; RANDOMIZED controlled trials; PRE-tests & post-tests; BLIND experiment; DATA analysis -- Software; DESCRIPTIVE statistics; ONE-way analysis of variance; China  
  Abstract Objective: This study aimed to find evidence of a synergistic effect of acupoint combinations by analyzing different brain regions activated after acupuncture at different acupoint combinations. Methods: A total of 57 healthy subjects were randomly distributed into three groups: LR3 plus KI3 acupoints, LR3 plus sham acupoint, or LR3 alone. They underwent a magnetic resonance imaging scan before and after acupuncture. The amplitude of low-frequency fluctuation (ALFF) and regional homogeneity (ReHo) values of different brain regions were analyzed to observe changes in brain function. Results: ALFF and ReHo produced an activated area in the cerebellum posterior lobe after acupuncture at LR3 plus KI3 acupoints versus LR3 alone. ALFF and ReHo revealed altered activity in Brodmann area 10 (BA10), BA18, and brainstem pons after acupuncture at LR3 plus sham acupoint compared with at LR3 alone. A comparison of acupuncture at LR3 plus KI3 acupoints with LR3 plus sham acupoint demonstrated an increase in BA6 of ALFF and a downregulation of ReHo. Conclusions: The increased number of brain regions with altered brain activity after acupuncture at acupoint combinations versus a single acupoint are evidence of the synergistic effect of acupoint combinations. BA6 was significantly activated after acupuncture at LR3 plus KI3 acupoints compared with at LR3 plus sham acupoint, suggesting that BA6 is the specific region of synergistic effect of acupoint combinations of LR3 plus KI3 acupoints. Affected brain regions were different between acupuncture at LR3 plus sham acupoint and LR3 alone, which indicates that the sham acupoint may have some psychological effect. However, the specific mechanism of acupoint combinations requires further research.  
  Address  
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  Time in Treatment Condition
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  Notes Accession Number: 118649823; Source Information: Oct2016, Vol. 22 Issue 10, p800; Subject Term: BRAIN -- Physiology; Subject Term: CEREBELLUM -- Physiology; Subject Term: CEREBRAL cortex -- Physiology; Subject Term: ACUPUNCTURE; Subject Term: ACUPUNCTURE points; Subject Term: ALTERNATIVE medicine; Subject Term: MAGNETIC resonance imaging; Subject Term: PROBABILITY theory; Subject Term: RESEARCH -- Finance; Subject Term: SAMPLING (Statistics); Subject Term: STATISTICS; Subject Term: T-test (Statistics); Subject Term: DATA analysis; Subject Term: BODY mass index; Subject Term: RANDOMIZED controlled trials; Subject Term: PRE-tests & post-tests; Subject Term: BLIND experiment; Subject Term: DATA analysis -- Software; Subject Term: DESCRIPTIVE statistics; Subject Term: ONE-way analysis of variance; Subject Term: ; Geographic Subject: CHINA; Geographic Subject: ; Number of Pages: 10p; ; Illustrations: 5 Diagrams, 3 Charts; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2280  
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Author Lei, H.; Chen, X.; Liu, S.; Chen, Z. url  openurl
  Title Effect of Electroacupuncture on Visceral and Hepatic Fat in Women with Abdominal Obesity: A Randomized Controlled Study Based on Magnetic Resonance Imaging Type of Study Journal Article
  Year 2017 Publication Journal of Alternative & Complementary Medicine Abbreviated Journal Journal of Alternative & Complementary Medicine  
  Volume 23 Issue 4 Pages 285-294  
  Keywords OBESITY -- Treatment; FATTY liver -- Prevention; ACUPUNCTURE points; ADIPOSE tissues; ALTERNATIVE medicine; Anthropometry; HUMAN body composition; CLINICAL trials; Electroacupuncture; LONGITUDINAL method; MAGNETIC resonance imaging; Mathematics; PROBABILITY theory; RESEARCH -- Finance; SAMPLING (Statistics); Statistics; T-test (Statistics); WOMEN -- Health; DATA analysis; BODY mass index; RANDOMIZED controlled trials; PRE-tests & post-tests; DATA analysis -- Software; WAIST circumference; DESCRIPTIVE statistics; ABDOMINAL adipose tissue; MANN Whitney U Test; China  
  Abstract Copyright of Journal of Alternative & Complementary Medicine is the property of Mary Ann Liebert, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)  
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  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 122401275; Source Information: Apr2017, Vol. 23 Issue 4, p285; Subject Term: OBESITY -- Treatment; Subject Term: FATTY liver -- Prevention; Subject Term: ACUPUNCTURE points; Subject Term: ADIPOSE tissues; Subject Term: ALTERNATIVE medicine; Subject Term: ANTHROPOMETRY; Subject Term: HUMAN body composition; Subject Term: CLINICAL trials; Subject Term: ELECTROACUPUNCTURE; Subject Term: LONGITUDINAL method; Subject Term: MAGNETIC resonance imaging; Subject Term: MATHEMATICS; Subject Term: PROBABILITY theory; Subject Term: RESEARCH -- Finance; Subject Term: SAMPLING (Statistics); Subject Term: STATISTICS; Subject Term: T-test (Statistics); Subject Term: WOMEN -- Health; Subject Term: DATA analysis; Subject Term: BODY mass index; Subject Term: RANDOMIZED controlled trials; Subject Term: PRE-tests & post-tests; Subject Term: DATA analysis -- Software; Subject Term: WAIST circumference; Subject Term: DESCRIPTIVE statistics; Subject Term: ABDOMINAL adipose tissue; Subject Term: MANN Whitney U Test; Subject Term: ; Geographic Subject: CHINA; Geographic Subject: ; Number of Pages: 10p; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2251  
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Author Lei, H.; Chen, X.; Liu, S.; Chen, Z. url  openurl
  Title Effect of Electroacupuncture on Visceral and Hepatic Fat in Women with Abdominal Obesity: A Randomized Controlled Study Based on Magnetic Resonance Imaging Type of Study Journal Article
  Year 2017 Publication Journal of Alternative & Complementary Medicine Abbreviated Journal Journal of Alternative & Complementary Medicine  
  Volume 23 Issue 4 Pages 285-294  
  Keywords OBESITY -- Treatment; FATTY liver -- Prevention; ACUPUNCTURE points; ADIPOSE tissues; ALTERNATIVE medicine; Anthropometry; HUMAN body composition; CLINICAL trials; Electroacupuncture; LONGITUDINAL method; MAGNETIC resonance imaging; Mathematics; PROBABILITY theory; RESEARCH -- Finance; SAMPLING (Statistics); Statistics; T-test (Statistics); WOMEN -- Health; DATA analysis; BODY mass index; RANDOMIZED controlled trials; PRE-tests & post-tests; DATA analysis -- Software; WAIST circumference; DESCRIPTIVE statistics; ABDOMINAL adipose tissue; MANN Whitney U Test; China  
  Abstract Objective: Visceral adipose tissue (VAT) and hepatic fat deposition are the most important risk factors for women's health. Acupuncture, including electroacupuncture (EA), is used to treat obesity throughout the world. The effect of EA is evaluated mainly by body mass index (BMI) and waist circumference (WC). Few studies have assessed its effect in reducing VAT volume and hepatic fat fraction (HFF) based on an exact measurement method such as magnetic resonance imaging (MRI). This study aimed to resolve this issue. Methods: Thirty subjects were randomly divided into two groups. The control group ( n = 15) did not receive any intervention and maintained a normal diet and their usual exercise habits. The treatment group ( n = 15) received EA three times a week for 3 months. BMI and WC were measured using different devices. VAT and HFF were measured by MRI and calculated by related software before and after the intervention. Results: A marked difference was evident in group that received EA treatment in the following tests. The differences in BMI (U = 21.00, p < 0.001), WC (U = 40.50, p = 0.002), VAT volume (U = 13.00, p < 0.001), and mean HFF (U = 0.00, p < 0.001) before and after the intervention in the treatment group were distinct and significant compared with those of the control group. Three months later, the treatment group showed a lower BMI (W = 91.00, p = 0.001), WC ( t = 4.755, p < 0.001), VAT volume ( t = 5.164, p < 0.001), and mean HFF (W = 120.00, p = 0.001) compared with pretreatment levels. Compared with the control group, the treatment group showed a lower VAT volume ( t = 60.00, p = 0.029) after 3 months of treatment. After 3 months, the control group showed higher mean HFF ( t = ?2.900, p = 0.012) and VAT volume (W = 11.50, p = 0.006) compared with their initial levels. Conclusion: Based on MRI evaluation, this randomized controlled study proved that EA treatment reduces BMI and WC as well as VAT volume and HFF in women with abdominal obesity.  
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  Publisher
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 122401275; Source Information: Apr2017, Vol. 23 Issue 4, p285; Subject Term: OBESITY -- Treatment; Subject Term: FATTY liver -- Prevention; Subject Term: ACUPUNCTURE points; Subject Term: ADIPOSE tissues; Subject Term: ALTERNATIVE medicine; Subject Term: ANTHROPOMETRY; Subject Term: HUMAN body composition; Subject Term: CLINICAL trials; Subject Term: ELECTROACUPUNCTURE; Subject Term: LONGITUDINAL method; Subject Term: MAGNETIC resonance imaging; Subject Term: MATHEMATICS; Subject Term: PROBABILITY theory; Subject Term: RESEARCH -- Finance; Subject Term: SAMPLING (Statistics); Subject Term: STATISTICS; Subject Term: T-test (Statistics); Subject Term: WOMEN -- Health; Subject Term: DATA analysis; Subject Term: BODY mass index; Subject Term: RANDOMIZED controlled trials; Subject Term: PRE-tests & post-tests; Subject Term: DATA analysis -- Software; Subject Term: WAIST circumference; Subject Term: DESCRIPTIVE statistics; Subject Term: ABDOMINAL adipose tissue; Subject Term: MANN Whitney U Test; Subject Term: ; Geographic Subject: CHINA; Geographic Subject: ; Number of Pages: 10p; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2228  
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Author Soliman, A.; O'Driscoll, G.A.; Pruessner, J.; Joober, R.; Ditto, B.; Streicker, E.; Goldberg, Y.; Caro, J.; Rekkas, P.V.; Dagher, A. openurl 
  Title Limbic response to psychosocial stress in schizotypy: a functional magnetic resonance imaging study Type of Study Journal Article
  Year 2011 Publication Schizophr Res Abbreviated Journal  
  Volume Issue Pages 184-91 LID - 10.1016/j.s  
  Keywords Adolescent; Brain Mapping; Female; Humans; Hydrocortisone/metabolism; Image Processing, Computer-Assisted; Limbic System/*blood supply; Linear Models; *Magnetic Resonance Imaging; Male; Oxygen/blood; Personality Inventory; Psychiatric Status Rating Scales; Saliva; Schizotypal Personality Disorder/complications/*pathology; Stress, Psychological/complications/*pathology; Young Adult  
  Abstract Psychological stress causes dopamine release in the striatum and is thought to play a role in susceptibility to psychotic illness. Previous work suggests that an elevated dopaminergic response to stress may index vulnerability to psychosis in certain individuals. With functional magnetic resonance imaging, we measured stress-induced changes in brain activity in healthy individuals at elevated risk of developing psychosis. Participants were 15 controls and 25 psychometric schizotypes: 12 with positive symptom schizotypy (perceptual aberrations) and 13 with negative symptom schizotypy (physical anhedonia), as determined by questionnaires (Chapman et al., 1976; Chapman and Chapman, 1978). In the scanner, participants performed the Montreal Imaging Stress Task and a matched sensory-motor control task. Measures of self-reported stress and salivary cortisol levels were taken throughout the experiment. All three groups showed significant increases in self-reported stress and significant fMRI signal change in the striatal, limbic and cortical regions. However, the Physical Anhedonia group showed greater stress-induced striatal and limbic deactivation than the other two groups. Deactivation in the striatum was significantly correlated with Physical Anhedonia score across all subjects. Our findings suggest the presence of abnormalities in striatal response to stress in negative symptom schizotypy.  
  Address  
  Publisher Copyright (c) 2011 Elsevier B.V. All rights reserved.
  Language Number of Treatments  
  Treatment Follow-up Frequency Schizophrenia research Number of Participants  
  Time in Treatment 131 Condition 1-3
  Disease Category OCSI Score  
  Notes Date of Input: 7/29/2015; Priority: Normal; McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, Canada.; eng; Web: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=21705195 Approved no  
  Call Number OCOM @ refbase @ Serial 1556  
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Author von Deneen, K.M.; Wei Qin; Peng Liu; Minghao Dong; Peng Chen; Huisheng Xie; Yi Zhang; Mark S. Gold; Yijun Liu; Jie Tian url  doi
openurl 
  Title Connectivity Study of the Neuromechanism of Acute Acupuncture Needling during fMRI in “Overweight” Subjects Type of Study Journal Article
  Year 2015 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evid Based Complement Altern Med  
  Volume Issue Pages 1-12  
  Keywords Obesity -- Therapy; Acupuncture; Magnetic Resonance Imaging; Human; Funding Source; Acupuncture Points; Body Temperature; Blood Glucose; Hunger; Brain -- Physiology; Male; China; Adult; Middle Age; Descriptive Statistics; Waist-Hip Ratio; Randomized Controlled Trials; T-Tests  
  Abstract This functional connectivity study depicts how acupoints ST 36 and SP 9 and their sham acupoints acutely act on blood glucose (GLU), core body temperature (CBT), hunger, and sensations pertaining to needling (De-qi) via the limbic system and dopamine (DA) to affect various brain areas in fasting, adult, and “overweight” Chinese males using functional magnetic resonance imaging. Functional connectivity (FC) analysis utilized the amygdala (AMY) and hypothalamus (HYP) as regions of interest (ROIs) in the discrete cosine transform and seed correlation analysis methods. There was a significant difference in the spatial patterns of the distinct brain regions between groups. Correlation results showed that increased HYP-hippocampus FC after ACU was positively correlated with ACU-induced change in CBT; increased HYP-putamen-insula FC after ACU was positively correlated with ACU-induced change in GLU; and increased HYP-anterior cingulate cortex FC after ACU was positively correlated with ACU-induced change in HUNGER suggesting that increased DA modulation during ACU was probably associated with increased poststimulation limbic system and spinothalamic tract connectivity. Decreased HYP-thalamus FC after ACU was negatively correlated or anticorrelated with ACU-induced change in HUNGER suggesting that increased DA modulation during ACU was possibly associated with decreased poststimulation limbic system and spinothalamic tract connectivity. No correlation was found for min SHAM. This was an important study in addressing acute acupuncture effects and neural pathways involving physiology and appetite regulation in overweight individuals.  
  Address Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, P O. Box 100126 2015 S W 16th Avenue, Gainesville, FL 32610, USA  
  Publisher Hindawi Limited
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
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  Notes Accession Number: 108824644. Language: English. Entry Date: 20170222. Revision Date: 20170222. Publication Type: journal article; diagnostic images; pictorial; research; tables/charts; randomized controlled trial. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. Grant Information: .This studywas financially supported by the National Natural ScienceFoundation of China under Grant nos. 81271549, 61131003,and 31150110171, Chinese Academy of Sciences Fellowship forYoung International Scientists no. 2013Y1GA0004, and theFundamental Research Funds for the Central Universities.. NLM UID: 101215021. Approved no  
  Call Number OCOM @ refbase @ 108824644 Serial 2327  
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Author Xiao, J.; Zhang, H.; Chang, J.-L.; Zhou, L.; Tan, Z.-J.; Zhong, H.-Z.; Zhu, D.; Gao, Y. url  doi
openurl 
  Title Effects of electro-acupuncture at Tongli (HT 5) and Xuanzhong (GB 39) acupoints from functional magnetic resonance imaging evidence Type of Study Journal Article
  Year 2016 Publication Chinese Journal of Integrative Medicine Abbreviated Journal Chin J Integr Med  
  Volume 22 Issue 11 Pages 846-854  
  Keywords Tongli (HT 5); Xuanzhong (GB 39); brain network; electroacupuncture; functional magnetic resonance imaging  
  Abstract OBJECTIVE: To explore the specifificity of Tongli (HT 5) and Xuanzhong (GB 39) paired acupionts in aspects of Deqi sensation and brain activation patterns during electroacupuncture. METHODS: In this study, 15 healthy subjects were enrolled. All participants suffered two kinds of functional magnetic resonance imaging (fMRI) examinations randomly: Examination A received electro-acupuncture (EA) at the bilateral Tongli (HT5) and Xuanzhong (GB 39) acupoints (ACU), and examination B received EA at bilateral non-acupoints (NAP). The subjects reported the feeling of Deqi at each examination later respectively. A multi-voxel pattern analysis method and Statistical Program for Social Sciences were used to analyze the data. RESULTS: The ACU group (Exam A) reported fullness, heaviness, numbness, soreness and throbbing of signifificantly greater intensity than the NAP group (Exam B). In addition, there was no statistical signifificance between two groups in aching, tingling, deep pressure, sharp pain, dull pain, warmness and cold. Meanwhile, fMRI data revealed differences between two groups in discriminating accuracy of brain somatosensory cortex and language-related cortices. CONCLUSIONS: Needling HT 5 and GB 39 may modulate language function through a complex brain network, suggesting that it may be benefificial to the recovery of language function in patients with aphasia.  
  Address Key Laboratory of Encephalopathy Treatment of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100700, China  
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  Notes PMID:26129898 Approved no  
  Call Number OCOM @ refbase @ Serial 2126  
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Author Zhang, Q.; Li, A.; Yue, J.; Zhang, F.; Sun, Z.; Li, X. url  doi
openurl 
  Title Using functional magnetic resonance imaging to explore the possible mechanism of the action of acupuncture at Dazhong ( KI 4) on the functional cerebral regions of healthy volunteers Type of Study Journal Article
  Year 2015 Publication Internal Medicine Journal Abbreviated Journal Intern Med J  
  Volume 45 Issue 6 Pages 669-671  
  Keywords Acupuncture; Brain -- Physiology; Magnetic Resonance Imaging -- Methods -- China; China; Human; Adult; Descriptive Statistics; Male; Randomized Controlled Trials  
  Abstract  
  Address Department of Acupuncture and Moxibustion, School of Acupuncture and Moxibustion of Heilongjiang University of Chinese Medicine  
  Publisher Wiley-Blackwell
  Language Number of Treatments  
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  Notes Accession Number: 109797210. Language: English. Entry Date: 20150617. Revision Date: 20160531. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Australia & New Zealand; Biomedical; Peer Reviewed. NLM UID: 101092952. Approved no  
  Call Number OCOM @ refbase @ 109797210 Serial 2320  
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Author Zhang, Y.; Bao, F.; Wang, Y.; Wu, Z. url  openurl
  Title Influence of acupuncture in treatment of knee osteoarthritis and cartilage repairing Type of Study Journal Article
  Year 2016 Publication American Journal of Translational Research Abbreviated Journal Am J Transl Res  
  Volume 8 Issue 9 Pages 3995-4002  
  Keywords Osteoarthritis; acupuncture therapy; cartilage; magnetic resonance imaging; physiotherapy  
  Abstract As two major non-operative methods, physiotherapy and acupuncture have been proved to be safe and effective in osteoarthritis (OA) treatment. However, only a little study focused on functions of both methods on cartilage repairing. The main goal of this research is to prove and compare effectiveness of acupuncture and physiotherapy on OA, and to explore their possible efficacy on cartilage repairing. One hundred knees of 50 participants with knee osteoarthritis (KOA) were randomly divided into acupuncture group and physiotherapy group. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used to evaluate the motor function of knee joints, followed by MRI scanning to measure T2 values in ten cartilage sub-regions in tibiofemoral joints. Significant lower scores of total WOMAC and three subscales on the 4th weekend were observed in both groups than those of the baseline (P < 0.01). For acupuncture group, scores of total WOMAC and three subscales for pain, stiffness and physical function on 4th weekend were significantly lower than those of the physiotherapy group (P < 0.01 and P < 0.05). T2 values in anterior medial tibial sub-region (MTa) and anterior lateral tibial sub-region (LTa) were significantly lower in acupuncture group on 4th weekend than those of the baseline (P < 0.05). No significant difference in T2 values was detected in physiotherapy group. These results indicate that acupuncture represents certain clinical effect on KOA which is superior compared with physiotherapy, and hint the possible roles of acupuncture in promoting cartilage repairing.  
  Address Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences Beijing, China  
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  Notes PMID:27725880; PMCID:PMC5040698 Approved no  
  Call Number OCOM @ refbase @ Serial 2141  
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