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Author (up) Wyon, Y.; Wijma, K.; Nedstrand, E.; Hammar, M. url  openurl
  Title A comparison of acupuncture and oral estradiol treatment of vasomotor symptoms in postmenopausal women Type of Study RCT
  Year 2004 Publication Abbreviated Journal Climacteric  
  Volume 7 Issue 2 Pages 153-164  
  Keywords CAM Control; Acu Versus > 1 Control; AcuTrials; Electroacupuncture; Hot Flashes; Penetrating Sham; Near Verum Acupoint Control; RCT; Relaxation Techniques; Restricted Modalities, Acupuncture Only; Superficial Needling Depth; Usual Care Control, Pharmaceutical; Usual Care Control, Physical; Fixed Acupuncture Protocol; TCM Acupuncture Style; Women's Health; Climacteric; Postmenopause  
  Abstract OBJECTIVE: To compare the effects of electro-acupuncture with oral estradiol and superficial needle insertion on hot flushes in postmenopausal women. MATERIAL AND METHODS: Forty-five postmenopausal women with vasomotor symptoms were randomized to electro-acupuncture, superficial needle insertion or oral estradiol treatment during 12 weeks, with 6 months' follow-up. The number and severity of flushes were registered daily and the Kupperman index and a general estimate of climacteric symptoms were completed before, during and after therapy. RESULTS: In the electro-acupuncture group, the mean number of flushes/24 h decreased from 7.3 to 3.5 (ANOVA, p < 0.001). Eleven of the 15 women had at least a 50% decrease in number of flushes (with a mean decrease of 82%). Superficial needle insertion decreased the number of flushes/24 h from 8.1 to 3.8 (p < 0.001). In seven out of 13 women, the number of flushes decreased by at least 50% (mean decrease 83%). In the estrogen group, the number of flushes decreased from 8.4 to 0.8 (p < 0.001). The decrease in number of flushes persisted during the 24-week follow-up period in all treatment groups. The Kupperman index and the general climacteric symptom score decreased, and remained unchanged 24 weeks after treatment in all groups (p < 0.001). Electro-acupuncture decreased the number of flushes/24 h significantly over time, but not to the same extent as the estrogen treatment. No significant difference in effect was found between electro-acupuncture and the superficial needle insertion. CONCLUSION: We suggest that acupuncture is a viable alternative treatment of vasomotor symptoms in postmenopausal women and cannot recommend superficial needle insertion as an inactive control treatment  
  Address Faculty of Health Sciences, University Hospital, Linkoping, Sweden  
  Language Number of Treatments 14  
  Treatment Follow-up 24 Weeks Frequency 1/WK Number of Participants 45  
  Time in Treatment 12 Weeks Condition Hot Flashes
  Disease Category Climacteric OCSI Score 68  
  Notes Approved no  
  Call Number Serial 1337  
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