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Author (up) Chai, Q.; Fei, Y.; Cao, H.; Wang, C.; Tian, J.; Liu, J. url  doi
  Title Acupuncture for melasma in women: a systematic review of randomised controlled trials Type of Study Systematic Review
  Year 2015 Publication Acupuncture in medicine : journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 33 Issue Pages 254-261  
  Keywords Acupuncture; Systematic Review; Skin Diseases; Melanosis; Melasma; Chloasma; Freckles; Women's Health  
  Abstract BACKGROUND: Melasma is a common facial skin disorder seen in women. Manual acupuncture (MA) is widely used alone or in combination with conventional treatments for melasma in China. OBJECTIVES: To assess the effectiveness and safety of MA for melasma, and explore the range of treatments applied. METHODS: Six databases were searched systematically for randomised controlled trials (RCTs) on acupuncture for melasma in women up to November 2014. RevMan software was used for data analysis. The Cochrane tool of Risk of Bias was used to assess the methodological quality of the RCTs. RESULTS: Eight RCTs involving 587 women were included. Seven studies used the encircling needling method, four studies used the quick needling method and four studies used intensive needle manipulations. Five studies provided individualised acupuncture treatments. Points used with highest frequency were SP6, ST36 and SP10. MA was compared with oral tranexamic acid, vitamin C and E, vitamin C and tamoxifen, topical 20% azelaic acid, hydroquinone, vitamin A and no treatment. Studies were too heterogeneous to conduct a meta-analysis. For global outcome measures, seven trials showed that MA groups were significantly better than the conventional treatments either with a better cure rate or with a better combined cure rate and markedly effective rate, and one trial did not (MA vs vitamin A). No acupuncture-related adverse events were reported. CONCLUSIONS: MA appeared to be beneficial and safe for women with melasma, but insufficient evidence was found to reach conclusions. The encircling needling method, the quick needling method, intensive needle manipulations and individualised points' selection were widely used. Well-designed trials are required. TRIAL REGISTRATION NUMBER: PROSPERO Systematic review registration: CRD42013006396.  
  Address Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China  
  Publisher Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition Melanosis
  Disease Category Skin Diseases OCSI Score  
  Notes Approved yes  
  Call Number OCOM @ refbase @ Serial 1600  
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