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Author (up) Noda, Y.; Izuno, T.; Tsuchiya, Y.; Hayasaka, S.; Matsumoto, K.; Murakami, H.; Ito, A.; Shinse, Y.; Suzuki, A.; Nakamura, M. url  doi
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  Title Acupuncture-induced changes of vagal function in patients with depression: A preliminary sham-controlled study with press needles Type of Study Journal Article
  Year 2015 Publication Complementary Therapies in Clinical Practice Abbreviated Journal Complement Ther Clin Pract  
  Volume 21 Issue 3 Pages 193-200  
  Keywords AcuTrials; Mental Disorders; Depressive Disorder; NRCT; Acupuncture; Acu Versus Sham; Press Tacks; Japanese Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Sham Control; Non Penetrating Sham, Mechanical; Sham Acupoint Control; Press Needles; Press Needle Acupuncture  
  Abstract To study the biological effects of acupuncture on depression, we hypothesized that acupuncture will exert its antidepressant effect through a bottom-up neuromodulation of the autonomic dysfunction in depression. The participants received press needle (PN) acupuncture for 72 h continuously in a sham-controlled design. Psychological assessments and Holter electrocardiography were performed before and after PN acupuncture. We evaluated their autonomic functions through the heart rate variability (HRV). As a result, following PN acupuncture participants showed significant improvement in the Beck's Depression Inventory scores (P = 0.031), systolic/diastolic blood pressures (P = 0.002/P = 0.011), and coefficient of variation of the R-R interval (P < 0.0001), compared to sham PN. The present findings showed PN acupuncture induced alterations in vagal function, blood pressure, and Beck's Depression Inventory scores. It was suggested that vagal stabilization effect by acupuncture may be associated with the therapeutic mechanism in depression.  
  Address Kanagawa Psychiatric Center, 2-5-1 Serigaya, Kohnan-ku, Yokohama, Kanagawa, 233-0006, Japan. Electronic address: motoaki@motoaki.com  
  Publisher
  Language English Number of Treatments 3  
  Treatment Follow-up 3 Days Frequency >1/WK Number of Participants 42  
  Time in Treatment 3 Days Condition Depressive Disorder
  Disease Category Mental Disorders OCSI Score  
  Notes PMID:26256139 Approved yes  
  Call Number OCOM @ refbase @ Serial 2028  
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