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Author (up) Zheng, Y.; Zhang, J.; Wang, Y.; Wang, Y.; Lan, Y.; Qu, S.; Tang, C.; Huang, Y. url  doi
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  Title Acupuncture Decreases Blood Pressure Related to Hypothalamus Functional Connectivity with Frontal Lobe, Cerebellum, and Insula: A Study of Instantaneous and Short-Term Acupuncture Treatment in Essential Hypertension Type of Study Journal Article
  Year 2016 Publication Evidence-Based Complementary and Alternative Medicine : ECAM Abbreviated Journal Evid Based Complement Alternat Med  
  Volume 2016 Issue Pages 6908710  
  Keywords  
  Abstract The therapeutic effects of acupuncture in decreasing blood pressure are ambiguous and underlying acupuncture in hypertension treatment has not been investigated. Our objective was to observe the change of quality of life and compare the differences in brain functional connectivity by investigating instantaneous and short-term acupuncture treatment in essential hypertension patients. A total of 30 patients were randomly divided into the LR3 group and sham acupoint group. Subjects received resting-state fMRI among preacupuncture, postinstantaneous, and short-term acupuncture treatment in two groups. Hypothalamus was selected as the seed point to analyze the changes in connectivity. We found three kinds of results: (1) There was statistical difference in systolic blood pressure in LR3 group after the short-term treatment and before acupuncture. (2) Compared with sham acupoint, acupuncture at LR3 instantaneous effects in the functional connectivity with seed points was more concentrated in the frontal lobe. (3) Compared with instantaneous effects, acupuncture LR3 short-term effects in the functional connectivity with seed points had more regions in frontal lobe, cerebellum, and insula. These brain areas constituted a neural network structure with specific functions that could explain the mechanism of therapy in hypertension patients by LR3 acupoint.  
  Address School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:27688791; PMCID:PMC5027048 Approved no  
  Call Number OCOM @ refbase @ Serial 2147  
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