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Author (up) Deng, G.; Wong, W. D.; Guillem, J.; Chan, Y.; Affuso, T.; Yeung, K. S.; Coleton, M.; Sjoberg, D.; Vickers, A.; Cassileth, B. url  doi
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  Title A Phase II, Randomized, Controlled Trial of Acupuncture for Reduction of Postcolectomy Ileus Type of Study RCT
  Year 2013 Publication Annals of surgical oncology Abbreviated Journal Ann Surg Oncol  
  Volume 20 Issue 4 Pages 1164-1169  
  Keywords AcuTrials; RCT; Gastrointestinal Diseases; Ileus; Acu + Usual Care Versus Sham + Usual Care; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Acupuncture; Electroacupuncture; Sham Control; Non Penetrating Sham, Mechanical; Non Penetrating Sham, Electrical; Verum Acupoint Control; Ileus, Postoperative; Colectomy  
  Abstract PURPOSE: Postoperative ileus (POI) prolongs hospital stay and increases risk of postoperative complications. We conducted a randomized, sham-controlled trial to evaluate whether acupuncture reduces POI more effectively than sham acupuncture. METHODS: Colon cancer patients undergoing elective colectomy were randomized to receive 30 min of true or sham acupuncture twice daily during their first 3 postoperative days. GI-3 (the later of the following two events: time that the patient first tolerated solid food, AND time that the patient first passed flatus OR a bowel movement) and GI-2 (the later of the following two events: time patient first tolerated solid food AND time patient first passed a bowel movement) were determined. Pain, nausea, vomiting, and use of pain medications were evaluated daily for the first 3 postoperative days. RESULTS: Ninety patients were randomized. Eighty-one received the allocated intervention: 39 in the true acupuncture group and 42 in the sham acupuncture group, all evaluated for the primary endpoint. The mean time to GI-3 was 149 h [standard deviation (SD) 71 h] and 146 (SD 62 h) after surgery for the acupuncture group and the sham acupuncture group (difference between means -2 h; 95 % confidence interval -31, 26; p = 0.9). No significant differences were found between groups for secondary endpoints. CONCLUSIONS: True acupuncture as provided in this study did not reduce POI more significantly than sham acupuncture. The study was limited by a standard deviation much larger than expected, suggesting that a study with a larger sample size might be required.  
  Address Integrative Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA, dengg@mskcc.org.  
  Publisher
  Language Number of Treatments 6  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants 90  
  Time in Treatment 1 Week Condition Ileus
  Disease Category Gastrointestinal Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 235  
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