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Author (up) Tianjun Wang; Lingling Wang; Wenjian Tao; Li Chen url  doi
  Title Acupuncture combined with an antidepressant for patients with depression in hospital: a pragmatic randomised controlled trial Type of Study Journal Article
  Year 2014 Publication Acupuncture in Medicine Abbreviated Journal Acupuncture Med  
  Volume 32 Issue 4 Pages 308-312  
  Keywords Acupuncture -- Evaluation; Combined Modality Therapy -- Evaluation; Depression -- Therapy; Treatment Outcomes; Hospitalization; Serotonin Uptake Inhibitors -- Therapeutic Use; Randomized Controlled Trials; Human; Middle Age; Adult; Data Analysis Software; Scales; Analysis of Variance; Aged; Confidence Intervals; Descriptive Statistics; Funding Source; Male; Female  
  Abstract Objective To assess the effectiveness of acupuncture combined with selective serotonin reuptake inhibitors (SSRIs) for patients with depression in hospital using a pragmatic randomised controlled trial. Methods 76 patients with depression were randomly divided into two groups (randomisation ratio 2:1 for treatment and control groups (CGs), respectively) and 71 patients completed the study. The 45 patients in the treatment group (TG) underwent acupuncture and received an SSRI and the 26 patients in the CG received an SSRI only. The 17-item Hamilton Depression Rating Scale (HDRS-17) was used to quantitatively assess patients after 1, 2, 4 and 6 weeks of treatment. Results The mean (SD) baseline total HDRS scores were 22.2 (0.60) and 22.1 (0.33) in the TG and CG, respectively. After the first week of treatment the HDRS score for the TG was reduced to 15.6 (0.81), significantly different from the score of 18.3 (0.55) for the CG, p<0.05. This significant difference was maintained to the end of the 6-week treatment period, when HDRS scores had fallen to 6.3 (0.49) and 8.2 (0.35) for the TG and CG, respectively. Conclusions Acupuncture combined with an SSRI showed a statistically significant benefit for patients with depression in hospital over the 6-week period compared with SSRIs alone. This reduction in symptoms started in the first week and continued throughout the 6 weeks of treatment.  
  Address Jiangsu Traditional Chinese Medicine Hospital, Nanjing, China  
  Publisher BMJ Publishing Group
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 103988637. Language: English. Entry Date: 20140815. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Grant Information: Opening Projects from the Laboratory of Acupuncture-Medicine, Nanjing University of Chinese Medicine (No JKA200505).. NLM UID: 9304117. Approved no  
  Call Number OCOM @ refbase @ 103988637 Serial 2355  
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