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Author (up) Wang, Y.-Y.; Li, X.-X.; Liu, J.-P.; Luo, H.; Ma, L.-X.; Alraek, T. url  doi
  Title Traditional Chinese medicine for chronic fatigue syndrome: A systematic review of randomized clinical trials Type of Study Journal Article
  Year 2014 Publication Complementary Therapies in Medicine Abbreviated Journal Complement Ther Med  
  Volume 22 Issue 4 Pages 826-833  
  Keywords Fatigue Syndrome, Chronic -- Therapy; Medicine, Chinese Traditional -- Methods; Acupuncture; Clinical Trials; Drugs, Chinese Herbal -- Therapeutic Use; Human; Professional Practice, Evidence-Based; Quality of Life; Systematic Review  
  Abstract BACKGROUND: There is no curative treatment for chronic fatigue syndrome (CFS). Traditional Chinese medicine (TCM) is widely used in the treatment of CFS in China. OBJECTIVE: To evaluate the effectiveness and safety of TCM for CFS. METHODS: The protocol of this review is registered at PROSPERO. We searched six main databases for randomized clinical trials (RCTs) on TCM for CFS from their inception to September 2013. The Cochrane risk of bias tool was used to assess the methodological quality. We used RevMan 5.1 to synthesize the results. RESULTS: 23 RCTs involving 1776 participants were identified. The risk of bias of the included studies was high. The types of TCM interventions varied, including Chinese herbal medicine, acupuncture, qigong, moxibustion, and acupoint application. The results of meta-analyses and several individual studies showed that TCM alone or in combination with other interventions significantly alleviated fatigue symptoms as measured by Chalder's fatigue scale, fatigue severity scale, fatigue assessment instrument by Joseph E. Schwartz, Bell's fatigue scale, and guiding principle of clinical research on new drugs of TCM for fatigue symptom. There was no enough evidence that TCM could improve the quality of life for CFS patients. The included studies did not report serious adverse events. CONCLUSIONS: TCM appears to be effective to alleviate the fatigue symptom for people with CFS. However, due to the high risk of bias of the included studies, larger, well-designed studies are needed to confirm the potential benefit in the future.  
  Address The National Research Center in Complementary and Alternative Medicine, NAFKAM, Department of Community Medicine, Faculty of Health Science, UiT The Arctic University of Norway, 9037 Tromsø, Norway. Electronic address:  
  Publisher Elsevier B.V.
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 103841765. Language: English. Entry Date: 20150501. Revision Date: 20150710. Publication Type: Journal Article; research; systematic review. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. NLM UID: 9308777. Approved no  
  Call Number OCOM @ refbase @ 103841765 Serial 2377  
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