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Author (up) Walker, J.; Sawhney, A.; Holm Hansen, C.; Ahmed, S.; Martin, P.; Symeonides, S.; Murray, G.; Sharpe, M. url  doi
  Title Treatment of depression in adults with cancer: a systematic review of randomized controlled trials Type of Study Journal Article
  Year 2014 Publication Psychological Medicine Abbreviated Journal Psychol Med  
  Volume 44 Issue 5 Pages 897-907  
  Keywords Depression -- Therapy; Cancer Patients; Depression -- Drug Therapy; Human; Systematic Review; Medline; Embase; Psycinfo; Cochrane Library; Antidepressive Agents -- Therapeutic Use; Adult; Sample Size; Antidepressive Agents -- Adverse Effects; Acupuncture; Funding Source  
  Abstract Background. Depression is a leading cause of disease burden worldwide and is especially problematic in people with chronic diseases, including cancer. Although depression can be effectively treated in the general population using antidepressant medication and psychological treatments, these treatments may have different benefits and harms in cancer patients. Previous reviews have not adequately addressed this topic. We therefore aimed to determine which, if any, treatments are effective for patients with diagnoses of both cancer and depression. Method. We conducted a systematic review of relevant randomized controlled trials identified through searches of Medline, EMBASE, PsycINFO and The Cochrane Central Register of Controlled Trials (CENTRAL). Results. Seven relatively small trials met the selection criteria. These provided some evidence that antidepressant medication, given alone or in combination with a psychological treatment, may be effective. We found no good evidence for psychological treatments given alone or for any other forms of treatment. Conclusions. There is very limited evidence from clinical trials to guide the treatment of cancer patients with a diagnosis of depression, especially for psychological treatments. High quality trials of treatments for depression in patients with cancer are urgently needed.  
  Address University of Edinburgh Centre for Population Health Sciences, Edinburgh, UK  
  Publisher Cambridge University Press
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 107899460. Language: English. Entry Date: 20140403. Revision Date: 20150712. Publication Type: Journal Article; research; systematic review; tables/charts. Journal Subset: Biomedical; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice; Psychiatry/Psychology. Grant Information: This work was funded by the charity Cancer Research UK (grant no. C5547/A7375).. NLM UID: 1254142. Approved no  
  Call Number OCOM @ refbase @ 107899460 Serial 2394  
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