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Author (up) Forbes, A.; Jackson, S.; Walter, C.; Quraishi, S.; Jacyna, M.; Pitcher, M. url  openurl
  Title Acupuncture for irritable bowel syndrome: A blinded placebo-controlled trial Type of Study RCT
  Year 2005 Publication Abbreviated Journal World J Gastroenterol  
  Volume 11 Issue 26 Pages 4040-4044  
  Keywords Acu Versus Sham; Acupuncture; AcuTrials; Gastrointestinal Diseases; Individualized Acupuncture Protocol; Penetrating Sham; Irritable Bowel Syndrome; RCT; Restricted Modalities, Acupuncture Only; Sham Acupoint Control; Sham Control; TCM Acupuncture Style; Traditional Diagnosis Based Point Selection; IBS  
  Abstract AIM: Irritable bowel syndrome (IBS) is a common disorder and many patients fail to find adequate relief from conventional therapies for their symptoms. This study tests the claim that acupuncture is effective for a majority of these patients. METHODS: A prospective, blinded, sham acupuncture-controlled trial of traditional Chinese acupuncture was performed at a single postgraduate teaching hospital in Europe. Sixty patients with well-established IBS were recruited. The blinded comparator was sham acupuncture administered by the second of two acupuncturists who alone was aware of the randomization, and who otherwise followed the prescription of the first. The primary end-point was a defined fall in the symptom score at 13 wk (by intention to treat). The prior expectation was a 30% placebo response, and a response rate of 70% from acupuncture, for which the study was adequately powered. RESULTS: Patients in treated and sham groups improved significantly during the study-mean improvement in scores being equal (minus 1.9) and significant for both (P<0.05; one-tailed t test). There was a small numeric but non-significant difference between the response rate in patients receiving acupuncture (40.7%) and sham treatment (31.2%). Several secondary end-points marginally favored active treatment, but an improved symptom score of any degree of magnitude occurred more often with sham therapy (65.6% vs 59.2%). For no criterion was statistical significance approached. CONCLUSION: Traditional Chinese acupuncture is relatively ineffective in IBS in the European hospital setting, and the magnitude of any effect appears insufficient to warrant investment in acupuncture services  
  Address St Mark's Hospital, Watford Road, Harrow HA1 3UJ, United Kingdom. lastair.forbes@ic.ac.uk  
  Publisher
  Language Number of Treatments 10  
  Treatment Follow-up 2 Weeks Frequency 1/WK Number of Participants 59  
  Time in Treatment 10 Weeks Condition Irritable Bowel Syndrome
  Disease Category Gastrointestinal Diseases OCSI Score 72  
  Notes Approved no  
  Call Number Serial 331  
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