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Author (up) Molassiotis, A.; Bardy, J.; Finnegan-John, J.; Mackereth, P.; Ryder, W. D.; Filshie, J.; Ream, E.; Eaton, D.; Richardson, A. url  doi
  Title A randomized, controlled trial of acupuncture self-needling as maintenance therapy for cancer-related fatigue after therapist-delivered acupuncture Type of Study RCT
  Year 2013 Publication Annals of oncology : official journal of the European Society for Medical Oncology / ESMO Abbreviated Journal Ann Oncol  
  Volume Issue Pages -  
  Keywords AcuTrials; RCT; Fatigue; Neoplasms; Acu Versus > 1 Control; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture + Other; CAM Control; Acu Versus Acu; No Treatment Control; Breast Cancer; Cancer  
  Abstract Background: Maintenance acupuncture is advocated by clinicians after successful clinic-based acupuncture. We aimed to assess the effectiveness of maintenance acupuncture in the management of cancer-related fatigue (CRF); treatment delivered by therapists or self-acupuncture/self-needling was compared with no maintenance treatment. Methods: Breast cancer patients who participated in a randomized trial of acupuncture for CRF management (reported elsewhere) were re-randomized to receive an additional four acupuncturist-delivered weekly sessions; four self-administered weekly acupuncture sessions (self-needling); or no acupuncture. Primary outcome was general fatigue (Multidimensional Fatigue Inventory). Mood, quality of life and safety were also assessed. Results: In total, 197 patients were re-randomized, with 65 to therapist-delivered sessions, 67 to self-acupuncture/self-needling and 65 to no further acupuncture. Primary outcome scores were equivalent between the therapist-delivered acupuncture and self-acupuncture (P > 0.05). A non-significant trend in improving fatigue was observed at the end of 4 weeks in the combined acupuncture arms (P = 0.07). There was no impact on mood or quality of life of the further acupuncture sessions at 18 weeks beyond the improvement observed in initial trial. Conclusion: Self-acupuncture is an acceptable, feasible and safe maintenance treatment for patients with CRF. However, overall, maintenance acupuncture did not yield important improvements beyond those observed after an initial clinic-based course of acupuncture.Trial Registration numberNCT00957112.  
  Address School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK.  
  Language Number of Treatments 10  
  Treatment Follow-up N/A Frequency 1/WK Number of Participants 197  
  Time in Treatment 10 Weeks Condition Fatigue
  Disease Category Neoplasms OCSI Score  
  Notes Approved no  
  Call Number Serial 881  
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