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Author Shin, J.; Park, H. url  doi
openurl 
  Title Effects of Auricular Acupressure on Constipation in Patients With Breast Cancer Receiving Chemotherapy: A Randomized Control Trial Type of Study Journal Article
  Year 2018 Publication Western Journal of Nursing Research Abbreviated Journal West J Nurs Res  
  Volume 40 Issue 1 Pages 67-83  
  Keywords Acupressure/*methods; Acupuncture, Ear/*methods; Adult; Breast Neoplasms/*drug therapy; Constipation/*chemically induced/etiology/*therapy; Female; Humans; Middle Aged; Quality of Life; Republic of Korea; *auricular acupressure; *breast cancer; *chemotherapy; *constipation; *nursing intervention  
  Abstract The purpose was to examine the effects of auricular acupressure to relieve constipation in patients with breast cancer who were undergoing chemotherapy. Participants were 52 patients with breast cancer receiving chemotherapy at E University Hospital, Seoul, Korea, randomized into two groups of equal size. For the experimental group, auricular acupressure was applied to seven auricular acupoints for 6 weeks using vaccaria seeds, whereas the control group received the usual care. Constipation-assessment scores of the experimental group were significantly lower compared with the control group ( p < .001). Stool-form scores of the experimental group were significantly higher compared with the control group ( p = .003). Patient Assessment of Constipation-Quality of Life scores of the experimental group were significantly lower compared with the control group ( p < .001). Auricular acupressure was effective at relieving constipation in patients with breast cancer receiving chemotherapy. Auricular acupressure was also a safe and acceptable nursing intervention.  
  Address 1 Ewha Womans University, Seoul, Republic of Korea  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:27903827 Approved no  
  Call Number OCOM @ refbase @ Serial 2956  
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S. url  doi
openurl 
  Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
  Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation  
  Volume 19 Issue 1 Pages 39-58  
  Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review  
  Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.  
  Address a RAND Corporation , Santa Monica , California , USA  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28151093 Approved no  
  Call Number OCOM @ refbase @ Serial 2955  
Permanent link to this record
 

 
Author Criado, M.B.; Santos, M.J.; Machado, J.; Goncalves, A.M.; Greten, H.J. url  doi
openurl 
  Title Effects of Acupuncture on Gait of Patients with Multiple Sclerosis Type of Study
  Year 2017 Publication Journal of Alternative and Complementary Medicine (New York, N.Y.) Abbreviated Journal J Altern Complement Med  
  Volume 23 Issue 11 Pages 852-857  
  Keywords *Acupuncture Therapy; Adult; Female; Gait/*physiology; Humans; Male; Middle Aged; Multiple Sclerosis/*physiopathology/*therapy; acupuncture; gait dysfunction; multiple sclerosis  
  Abstract BACKGROUND: Multiple sclerosis is considered a complex and heterogeneous disease. Approximately 85% of patients with multiple sclerosis indicate impaired gait as one of the major limitations in their daily life. Acupuncture studies found a reduction of spasticity and improvement of fatigue and imbalance in patients with multiple sclerosis, but there is a lack of studies regarding gait. DESIGN: We designed a study of acupuncture treatment, according to the Heidelberg model of Traditional Chinese Medicine (TCM), to investigate if acupuncture can be a useful therapeutic strategy in patients with gait impairment in multiple sclerosis of relapsing-remitting type. The sample consisted of 20 individuals with diagnosis of multiple sclerosis of relapsing-remitting type. Gait impairment was evaluated by the 25-foot walk test. RESULTS: The results showed differences in time to walk 25 feet following true acupuncture. In contrast, there was no difference in time to walk 25 feet following sham acupuncture. When using true acupuncture, 95% of cases showed an improvement in 25-foot walk test, compared with 45% when sham acupuncture was done. CONCLUSIONS: Our study protocol provides evidence that acupuncture treatment can be an attractive option for patients with multiple sclerosis, with gait impairment.  
  Address 4 Heidelberg School of Chinese Medicine , Heidelberg, Germany  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28410453 Approved no  
  Call Number OCOM @ refbase @ Serial 2954  
Permanent link to this record
 

 
Author Cai, Y.; Zhang, C.S.; Liu, S.; Wen, Z.; Zhang, A.L.; Guo, X.; Lu, C.; Xue, C.C. url  doi
openurl 
  Title Electroacupuncture for Poststroke Spasticity: A Systematic Review and Meta-Analysis Type of Study Journal Article
  Year 2017 Publication Archives of Physical Medicine and Rehabilitation Abbreviated Journal Arch Phys Med Rehabil  
  Volume 98 Issue 12 Pages 2578-2589.e4  
  Keywords Electroacupuncture/*methods; Humans; Muscle Spasticity/*rehabilitation; Stroke Rehabilitation/*methods; Upper Extremity; *Acupuncture; *Meta-Analysis; *Muscle spasticity; *Rehabilitation; *Stroke  
  Abstract OBJECTIVE: To evaluate the effects and safety of electroacupuncture (EA) for stroke patients with spasticity. DATA SOURCES: Five English databases (PubMed, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database) and 4 Chinese databases (Chinese Biomedical Database, Chinese National Knowledge Infrastructure, Chongqing VIP Database, Wanfang Database) were searched from their inception to September 2016. STUDY SELECTION: Randomized controlled trials were included if they measured spasticity with the Modified Ashworth Scale (MAS) in stroke patients and investigated the add-on effects of electroacupuncture to routine pharmacotherapy and rehabilitation therapies. DATA EXTRACTION: Information on patients, study design, treatment details and outcomes assessing spasticity severity, motor function, and activities of daily living was extracted. DATA SYNTHESIS: In total, 22 trials involving 1425 participants met the search criteria and were included. The estimated add-on effects of EA to reduce spasticity in the upper limbs as measured by the MAS (standardized mean difference [SMD]=-.57; 95% confidence interval [CI], -.84 to -.29), and to improve overall motor function as measured by the Fugl-Meyer Assessment of Sensorimotor Recovery (mean difference [MD]=10.60; 95% CI, 8.67-12.53) were significant. Significant add-on effects of EA were also shown for spasticity in the lower limbs, lower-limb motor function, and activities of daily living ([SMD=-.88; 95% CI, -1.42 to -.35;], [MD=4.42; 95% CI, .06-8.78], and [MD=6.85; 95% CI, 3.64-10.05], respectively), although with high heterogeneity. For upper-limb motor function, no significant add-on effects of EA were found. CONCLUSIONS: EA combined with conventional routine care has the potential of reducing spasticity in the upper and lower limbs and improving overall and lower extremity motor function and activities of daily living for patients with spasticity, within 180 days poststroke. Further studies of high methodological and reporting quality are needed to confirm the effects and safety of EA, and to explore the adequate and optimal protocol of EA for poststroke spasticity, incorporating a group of comprehensive outcome measures in different populations.  
  Address China-Australia International Research Centre for Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia; Guangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Chinese Medicine), Guangdong Provincial Academy of Chinese Medical Sciences, and The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China. Electronic address: charlie.xue@rmit.edu.au  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28455191 Approved no  
  Call Number OCOM @ refbase @ Serial 2953  
Permanent link to this record
 

 
Author Yeh, M.-L.; Ko, S.-H.; Wang, M.-H.; Chi, C.-C.; Chung, Y.-C. url  doi
openurl 
  Title Acupuncture-Related Techniques for Psoriasis: A Systematic Review with Pairwise and Network Meta-Analyses of Randomized Controlled Trials Type of Study Journal Article
  Year 2017 Publication Journal of Alternative and Complementary Medicine (New York, N.Y.) Abbreviated Journal J Altern Complement Med  
  Volume 23 Issue 12 Pages 930-940  
  Keywords Acupressure/*methods; Acupuncture Points; Acupuncture Therapy/*methods; Humans; Network Meta-Analysis; Psoriasis/*therapy; Randomized Controlled Trials as Topic/statistics & numerical data; acupoint stimulation; acupressure; acupuncture; bloodletting; catgut embedding; network meta-analysis; pairwise meta-analysis; psoriasis; systematic review  
  Abstract OBJECTIVE: There has be a large body of evidence on the pharmacological treatments for psoriasis, but whether nonpharmacological interventions are effective in managing psoriasis remains largely unclear. This systematic review conducted pairwise and network meta-analyses to determine the effects of acupuncture-related techniques on acupoint stimulation for the treatment of psoriasis and to determine the order of effectiveness of these remedies. METHODS: This study searched the following databases from inception to March 15, 2016: Medline, PubMed, Cochrane Central Register of Controlled Trials, EBSCO (including Academic Search Premier, American Doctoral Dissertations, and CINAHL), Airiti Library, and China National Knowledge Infrastructure. Randomized controlled trials (RCTs) on the effects of acupuncture-related techniques on acupoint stimulation as intervention for psoriasis were independently reviewed by two researchers. RESULTS: A total of 13 RCTs with 1,060 participants were included. The methodological quality of included studies was not rigorous. Acupoint stimulation, compared with nonacupoint stimulation, had a significant treatment for psoriasis. However, the most common adverse events were thirst and dry mouth. Subgroup analysis was further done to confirm that the short-term treatment effect was superior to that of the long-term effect in treating psoriasis. Network meta-analysis identified acupressure or acupoint catgut embedding, compared with medication, and had a significant effect for improving psoriasis. It was noted that acupressure was the most effective treatment. CONCLUSIONS: Acupuncture-related techniques could be considered as an alternative or adjuvant therapy for psoriasis in short term, especially of acupressure and acupoint catgut embedding. This study recommends further well-designed, methodologically rigorous, and more head-to-head randomized trials to explore the effects of acupuncture-related techniques for treating psoriasis.  
  Address 5 Department of Nursing, Yuanpei University of Medical Technology , Hsinchu, Taiwan, Republic of China  
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  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28628749 Approved no  
  Call Number OCOM @ refbase @ Serial 2952  
Permanent link to this record
 

 
Author Zhang, R.-Q.; Tan, J.; Li, F.-Y.; Ma, Y.-H.; Han, L.-X.; Yang, X.-L. url  doi
openurl 
  Title Acupuncture for the treatment of obesity in adults: a systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication Postgraduate Medical Journal Abbreviated Journal Postgrad Med J  
  Volume 93 Issue 1106 Pages 743-751  
  Keywords Meta-analysis; Rct; acupuncture; obesity; treatment  
  Abstract OBJECTIVE: Meta-analysis was used to assess the clinical efficacy of acupuncture treatment for simple obesity and to provide evidence-based medical data for treating obesity with acupuncture. METHODS: A comprehensive search of studies on MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and Chinese databases (Wan Fang,CNKI and VIP) from 1 January 1915 through 30 November 2015 (MEDLINE search updated through 31 December 2015) was performed. We included only randomised controlled trials (RCTs) that used acupuncture and sham acupuncture to treat simple obesity. The effect of acupuncture on simple obesity was measured using body mass index (BMI), body fat mass (BFM), waist circumference (WC), hip circumference (HC), and body weight (BW). The Jadad scale was used to assess methodological quality. The random effects model was used in the pooled analysis to adjust for the heterogeneity of the included studies, and funnel plots were used to examine publication bias. The differences between treatment groups were reported as mean differences (MD). RESULTS: Eleven RCTs were selected after all relevant literature from the electronic databases had been screened. There were 338 and 305 participants in the acupuncture and sham acupuncture groups, respectively. Auricular and electro acupuncture were both able to reduce BMI in obese patients (MD 0.47 kg/m(2), 95% CI 0.35 to 0.58, p<0.001; MD 0.50 kg/m(2), 95% CI 0.38 to 0.62, p<0.001). BFM change after acupuncture treatment compared with sham treatment was statistically significant (MD 0.66 kg, 95% CI 0.51 to 0.80, p<0.001). There were also significant differences in WC and HC between the acupuncture and sham acupuncture groups (MDwc2.02 cm, 95% CI 0.21 to 3.83, p=0.03; MDHC2.74 cm, 95% CI 1.21 to 4.27, p=0.0004). BW was not statistically significantly different between the acupuncture and sham acupuncture groups (MD 0.60 kg, 95% CI -0.20 to 1.39, p=0.14). Begg's test and funnel plots showed that the potential publication bias of the included studies was very slight (p>0.05). CONCLUSION: Acupuncture for simple obesity appeared to be an effective treatment, but more studies on the safety of acupuncture used to treat simple obesity are required.  
  Address Institute of Endemic Diseases of School of Public Health, Xi'an Jiaotong University Health Science Center, Key Laboratory of Trace Elements and Endemic Diseases of the National Health and Family Planning Commission, Xi'an 710061, Shaanxi, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28689171 Approved no  
  Call Number OCOM @ refbase @ Serial 2951  
Permanent link to this record
 

 
Author Liu, L.; Huang, Q.-M.; Liu, Q.-G.; Thitham, N.; Li, L.-H.; Ma, Y.-T.; Zhao, J.-M. url  doi
openurl 
  Title Evidence for Dry Needling in the Management of Myofascial Trigger Points Associated With Low Back Pain: A Systematic Review and Meta-Analysis Type of Study Journal Article
  Year 2018 Publication Archives of Physical Medicine and Rehabilitation Abbreviated Journal Arch Phys Med Rehabil  
  Volume 99 Issue 1 Pages 144-152.e2  
  Keywords Combined Modality Therapy; *Complementary Therapies; Humans; Low Back Pain/complications/*therapy; Myofascial Pain Syndromes/complications/*therapy; Needles; Pain Measurement; Randomized Controlled Trials as Topic; *Trigger Points; *Low back pain; *Meta-analysis [publication type]; *Needles; *Randomized controlled trial as topic; *Rehabilitation; *Trigger points  
  Abstract OBJECTIVE: To evaluate the current evidence of the effectiveness of dry needling of myofascial trigger points (MTrPs) associated with low back pain (LBP). DATA SOURCES: PubMed, Ovid, EBSCO, ScienceDirect, Web of Science, Cochrane Library, CINAHL, and China National Knowledge Infrastructure databases were searched until January 2017. STUDY SELECTION: Randomized controlled trials (RCTs) that used dry needling as the main treatment and included participants diagnosed with LBP with the presence of MTrPs were included. DATA EXTRACTION: Two reviewers independently screened articles, scored methodologic quality, and extracted data. The primary outcomes were pain intensity and functional disability at postintervention and follow-up. DATA SYNTHESIS: A total of 11 RCTs involving 802 patients were included in the meta-analysis. Results suggested that compared with other treatments, dry needling of MTrPs was more effective in alleviating the intensity of LBP (standardized mean difference [SMD], -1.06; 95% confidence interval [CI], -1.77 to -0.36; P=.003) and functional disability (SMD, -0.76; 95% CI, -1.46 to -0.06; P=.03); however, the significant effects of dry needling plus other treatments on pain intensity could be superior to dry needling alone for LBP at postintervention (SMD, 0.83; 95% CI, 0.55-1.11; P<.00001). CONCLUSIONS: Moderate evidence showed that dry needling of MTrPs, especially if associated with other therapies, could be recommended to relieve the intensity of LBP at postintervention; however, the clinical superiority of dry needling in improving functional disability and its follow-up effects still remains unclear.  
  Address Department of Sport Medicine and the Center of Rehabilitation, School of Sport Science, Shanghai University of Sport, Shanghai, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28690077 Approved no  
  Call Number OCOM @ refbase @ Serial 2950  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
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  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2949  
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Author Cho, S.-Y.; Lee, Y.-E.; Doo, K.-H.; Lee, J.-H.; Jung, W.-S.; Moon, S.-K.; Park, J.-M.; Ko, C.-N.; Kim, H.; Rhee, H.Y.; Park, H.-J.; Park, S.-U. url  doi
openurl 
  Title Efficacy of Combined Treatment with Acupuncture and Bee Venom Acupuncture as an Adjunctive Treatment for Parkinson's Disease Type of Study
  Year 2018 Publication Journal of Alternative and Complementary Medicine (New York, N.Y.) Abbreviated Journal J Altern Complement Med  
  Volume 24 Issue 1 Pages 25-32  
  Keywords *Acupuncture Therapy; Aged; Bee Venoms/*therapeutic use; Female; Humans; Male; Middle Aged; Parkinson Disease/*therapy; Treatment Outcome; Parkinson's disease; acupuncture; bee venom acupuncture  
  Abstract OBJECTIVE: The aim of this study was to evaluate the efficacy of acupuncture and bee venom acupuncture (BVA) for idiopathic Parkinson's disease (IPD) through a sham-controlled trial. We also investigated whether there is a sustained therapeutic effect by completing follow-up assessments after treatment completion. DESIGN: A single center, double-blind, three-armed randomized controlled trial. SETTINGS/LOCATION: This study was performed at a university hospital in Seoul, Republic of Korea. SUBJECTS: Seventy-three (73) patients with IPD were the subjects. They were randomly assigned to the active treatment group, sham treatment group, or conventional treatment group. INTERVENTIONS: The active treatment group received acupuncture and BVA and the sham group received sham acupuncture and normal saline injections, twice a week for 12 weeks. The conventional treatment group maintained anti-parkinsonian drugs without additional intervention. OUTCOME MEASURES: The Unified Parkinson's Disease Rating Scale (UPDRS) part II and part III score, postural instability and gait disturbance (PIGD) score, gait speed and number, Parkinson's Disease Quality of Life Questionnaire, Beck Depression Inventory, and postural stability at baseline and at 12, 16, and 20 weeks. RESULTS: Sixty-three (63) patients provided a complete data of assessments, including a final follow-up. After 12 weeks of treatment, a significant difference was observed between the active treatment group and the conventional treatment group. After the end of the treatment, the treatment effects were maintained significantly in the active treatment group only. CONCLUSIONS: It is suggested that the combined treatment of acupuncture and BVA might be safe and useful adjunctive treatment for patients with IPD.  
  Address 2 Stroke and Neurological Disorders Center, Kyung Hee University Hospital at Gangdong , Seoul, Republic of Korea  
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  Notes PMID:28753030 Approved no  
  Call Number OCOM @ refbase @ Serial 2948  
Permanent link to this record
 

 
Author Zhang, B.; Zhu, Y.; Jiang, C.; Li, C.; Li, Y.; Bai, Y.; Wu, Y. url  doi
openurl 
  Title Effects of Transcutaneous Electrical Acupoint Stimulation on Motor Functions and Self-Care Ability in Children with Cerebral Palsy Type of Study
  Year 2018 Publication Journal of Alternative and Complementary Medicine (New York, N.Y.) Abbreviated Journal J Altern Complement Med  
  Volume 24 Issue 1 Pages 55-61  
  Keywords *Acupuncture Points; Cerebral Palsy/*physiopathology/*therapy; Child, Preschool; Female; Humans; Male; Motor Skills/*physiology; Self Care/*methods; *Transcutaneous Electric Nerve Stimulation; cerebral palsy; motor function; self-care; transcutaneous electrical acupoint stimulation  
  Abstract OBJECTIVES: To observe the effects of transcutaneous electrical acupoint stimulation (TEAS) in improving motor functions and self-care abilities in children with cerebral palsy in their early childhood. DESIGN: A preliminary, prospective, cohort study. SETTINGS/LOCATION: Multicenter. SUBJECTS: Children aged 2-6 years old. INTERVENTIONS: Twenty-three children were included in the study and randomly assigned to a control group ([CG] N = 11) or a therapeutic group ([TG] N = 12). In the TG, children were treated with TEAS (Shousanli [LI10] and Waiguan [SJ5]) plus the exercise therapy, while in the control group, they were treated with sham TEAS plus exercise therapy. Therapies were performed five days per week for eight weeks. OUTCOME MEASURES: The Gross Motor Function Measure (GMFM) and the Functional Independent Measurement for children (WeeFIM) were used to evaluate motor functions and self-care abilities before and after the therapies. RESULTS: Greater improvements were observed in the TG concerning all the measurements, although without statistical differences. The increments of the GMFM score and the WeeFIM motor, self-care and total scores were 36.08 +/- 18.34 (26%), 16.17 +/- 8.21 (33%), 7.67 +/- 3.42 (40%) and 20.33 +/- 10.08 (28%) in the TG, while 22.73 +/- 16.54 (17%), 9.09 +/- 9.43 (19%), 5.64 +/- 6.73 (29%) and 12.82 +/- 11.77 (18%) in the CG, respectively. No statistically significant correlations were shown between functional improvements and the demographics in the TG or the CG. The GMFM improvement was not statistically correlated with the improvements of the WeeFIM motor, self-care or total scores. However, the WeeFIM motor, self-care and total score were significantly positively correlated with one another in both groups (P < 0.01). No adverse effect was recorded during the study. CONCLUSION: TEAS may be effective in improving motor functions and self-care abilities in children with cerebral palsy, in addition to conventional exercise therapy. Larger samples are required to confirm the efficacies.  
  Address Department of Rehabilitation Medicine, Huashan Hospital, Fudan University , Shanghai, People's Republic of China  
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  Notes PMID:28767271 Approved no  
  Call Number OCOM @ refbase @ Serial 2947  
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Author Liu, T.; Yu, J.-N.; Cao, B.-Y.; Peng, Y.-Y.; Chen, Y.-P.; Zhang, L. url  openurl
  Title Acupuncture for Primary Dysmenorrhea: A Meta-analysis of Randomized Controlled Trials Type of Study Journal Article
  Year 2017 Publication Alternative Therapies in Health and Medicine Abbreviated Journal Altern Ther Health Med  
  Volume Issue Pages  
  Keywords  
  Abstract Context * Primary dysmenorrhea (PD) is one of the most common complaints among young women. Acupuncture has been widely applied as a therapeutic modality in China and abroad for PD; however, the evidence for its benefits is still not convincing. Objective * The study intended to conduct a systematic review of randomized, controlled trials (RCTs) to evaluate the evidence regarding the use of acupuncture in treating PD. Design * The research team retrieved reports for RCTs published in 7 databases from their inception to March 2016, with no language restrictions: PubMed, Medline, Embase, the Cochrane Central Register of Controlled Trials, the Chinese National Knowledge Infrastructure database, the Chinese Biomedical database, and the Wanfang database. Setting * The study was conducted at the Beijing University of Traditional Chinese Medicine (Beijing, China). Participants * Participants in the reviewed studies were women aged 14 to 49 y who had received a diagnosis of PD in the absence of any visible pelvic pathology. Interventions * The types of acupuncture included traditional acupuncture, electroacupuncture, ear acupuncture, scalp acupuncture, superficial acupuncture, electrosuperficial acupuncture, wrist-ankle acupuncture, and abdominal acupuncture. Outcome Measures * The primary outcome was pain relief measured using a visual analogue scale (VAS), a verbal rating scale (VRS), or a numerical rating scale (NRS). The secondary outcomes included (1) overall improvement as measured by the short-form McGill pain questionnaire or symptom scale based on the Clinical Study Guideline for New Developed Chinese Medicine, (2) menstrual distress as measured by the Menstrual Distress Questionnaire, (3) quality of life as measured by a validated scale (eg, the short-form 36), and (4) adverse effects. Results * Twenty-three trials enrolling a total of 2770 patients were included in the review. Overall, most trials were of poor quality. Among the trials, only 6 were evaluated as having a low risk of bias, 3 of which indicated that acupuncture was statistically more effective than sham acupuncture-mean difference (MD), -3.51; 95% confidence interval (CI), -5.27 to -1.75; P < .0001; I(2), 0%-or no treatment-MD, -21.95; 95% CI, -25.45 to -18.45; P < .00001; I(2), 0%-on the VAS (0 to 100 mm). Acupuncture also showed superiority to the control arms on the VRS, the NRS, and the McGill pain questionnaire, but those findings had been influenced by methodological flaws. Conclusions * The available evidence suggests that acupuncture may be effective for PD and justifies future high-quality studies.  
  Address  
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  Notes PMID:29112942 Approved no  
  Call Number OCOM @ refbase @ Serial 2946  
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Author Liang, Y.; Lenon, G.B.; Yang, A.W.H. url  doi
openurl 
  Title Acupressure for respiratory allergic diseases: a systematic review of randomised controlled trials Type of Study Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 413-420  
  Keywords Acupressure; Acupuncture Points; Acupuncture Therapy/*methods; Asthma/complications/*therapy; Humans; Randomized Controlled Trials as Topic; Rhinitis, Allergic/complications/*therapy; Chinese medicine; acupuncture; allergic rhinitis; asthma; hay fever  
  Abstract OBJECTIVE: To evaluate the effects and safety of acupressure for the management of respiratory allergic diseases by systematically reviewing randomised controlled trials (RCTs). METHODS: A total of 13 electronic English and Chinese databases were searched until July 2017. Two authors extracted data and evaluated risk of bias independently. Review Manager V.5.3 was employed for data analysis. RESULTS: The literature search identified 186 papers, of which only four of met the inclusion criteria: two for allergic rhinitis (AR) and two for asthma. High and unclear risk of bias existed across all the included studies. The findings demonstrated that acupressure greater effects on the relief of nasal symptoms of AR compared with 1% ephedrine nasal drop plus thermal therapy. With either Western medicine or Chinese herbal medicine as a cointervention, one study indicated that acupressure plus salbutamol was led to a significantly greater improvement of pulmonary function for patients with asthma compared with salbutamol only. However, the remaining two studies indentified no significant differences in any outcome measures between the two groups. CONCLUSIONS: No reliable conclusions regarding the effects of acupressure on AR and asthma could be drawn by this review due to the small number of available trials with significant heterogeneity of study design and high/unclear risk of bias. Further, more rigorously designed RCTs are needed. Acupressure seems safe for symptomatic relief of AR and asthma, although larger studies are required to be able to robustly confirm its safety. TRIAL REGISTRATION NUMBER: ACTRN12617001106325; Pre-results.  
  Address Discipline of Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia  
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  Notes PMID:29113981 Approved no  
  Call Number OCOM @ refbase @ Serial 2945  
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Author Zhang, Q.; Yue, J.; Golianu, B.; Sun, Z.; Lu, Y. url  doi
openurl 
  Title Updated systematic review and meta-analysis of acupuncture for chronic knee pain Type of Study Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 392-403  
  Keywords *Acupuncture Therapy; Arthralgia/*therapy; Humans; Osteoarthritis, Knee/*therapy; Pain Management; Pain Measurement; Research Design; Treatment Outcome; acupuncture; auricular acupuncture; electroacupuncture; pain management; pain research  
  Abstract OBJECTIVE: To assess the effectiveness and safety of acupuncture for the treatment of chronic knee pain (CKP). METHODS: We searched the MEDLINE, EMBASE, Cochrane CENTERAL, CINAHL and four Chinese medical databases from their inception to June 2017. We included randomised controlled trials of acupuncture as the sole treatment or as an adjunctive treatment for CKP. The primary outcome was pain intensity measured by visual analogue scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale and 11-point numeric rating scale. Secondary outcome measurements included the 36-Item Short Form Health Survey and adverse events. The quality of all included studies was evaluated using the Cochrane risk-of-bias criteria and the STRICTA (Standards for Reporting Interventions in Controlled Trials of Acupuncture) checklist. RESULTS: Nineteen trials were included in this systematic review. Of these, data from 17 studies were available for analysis. Regarding the effectiveness of acupuncture alone or combined with other treatment, the results of the meta-analysis showed that acupuncture was associated with significantly reduced CKP at 12 weeks on WOMAC pain subscale (mean difference (MD) -1.12, 95% confidence interval (CI) -1.98 to -0.26, I(2)=62%, 3 trials, 608 participants) and VAS (MD -10.56, 95% CI -17.69 to -3.44, I(2)=0%, 2 trials, 145 patients). As for safety, no difference was found between the acupuncture and control groups (risk ratio 1.08, 95% CI 0.54 to 2.17, I(2)=29%). CONCLUSION: From this systematic review, we conclude that acupuncture may be effective at relieving CKP 12 weeks after acupuncture administration, based on the current evidence and our protocol. However, given the heterogeneity and methodological limitations of the included trials, we are currently unable to draw any strong conclusions regarding the effectiveness of acupuncture for chronic knee pain. In addition, we found that acupuncture appears to have a satisfactory safety profile, although further studies with larger numbers of participants are needed to confirm the safety of this technique. STRENGTHS: Systematic review without language restrictions. LIMITATIONS: Only a few high-quality and consistent trials could be included in this review.  
  Address Department of Biomedical Data Science, Stanford University, Stanford, California, USA  
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  Notes PMID:29117967 Approved no  
  Call Number OCOM @ refbase @ Serial 2944  
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Author Seo, S.Y.; Lee, K.-B.; Shin, J.-S.; Lee, J.; Kim, M.-R.; Ha, I.-H.; Ko, Y.; Lee, Y.J. url  doi
openurl 
  Title Effectiveness of Acupuncture and Electroacupuncture for Chronic Neck Pain: A Systematic Review and Meta-Analysis Type of Study
  Year 2017 Publication The American Journal of Chinese Medicine Abbreviated Journal Am J Chin Med  
  Volume 45 Issue 8 Pages 1573-1595  
  Keywords *Acupuncture Therapy; Chronic Disease; Databases, Bibliographic; *Electroacupuncture; Humans; Neck Pain/*therapy; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome; Acupuncture; Effectiveness; Electroacupuncture; Meta-Analysis; Review; Safety; Systematic Review  
  Abstract The aim of this systematic review was to assess evidence from randomized controlled trials (RCTs) on the effectiveness and safety of acupuncture and electroacupuncture in patients with chronic neck pain. We searched nine databases including Chinese, Japanese and Korean databases through 30 July 2016. The participants were adults with chronic neck pain and were treated with acupuncture or electroacupuncture. Eligible trials were those with intervention groups receiving acupuncture and electroacupuncture with or without active control, and control groups receiving other conventional treatments such as physical therapy or medication. Outcomes included pain intensity, disability, quality of life (QoL) and adverse effects. For statistical pooling, the standardized mean difference (SMD) and its 95% confidence interval (CI) were calculated using a fixed-effects model. Sixteen RCTs were selected. The comparison of the sole acupuncture group and the active control group did not come out with a significant difference in pain (SMD 0.24, 95% CI [Formula: see text]0.27-0.75), disability (SMD 0.51, 95% CI [Formula: see text]0.01-1.02), or QoL (SMD [Formula: see text]0.37, 95% CI [Formula: see text]1.09-0.35), showing a similar effectiveness of acupuncture with active control. When acupuncture was added into the control group, the acupuncture add-on group showed significantly higher relief of pain in studies with unclear allocation concealment (SMD [Formula: see text]1.78, 95% CI [Formula: see text]2.08-[Formula: see text]1.48), but did not show significant relief of pain in studies with good allocation concealment (SMD [Formula: see text]0.07, 95% CI [Formula: see text]0.26-0.12). Significant relief of pain was observed when the sole electroacupuncture group was compared to the control group or electroacupuncture was added onto the active control group, but a lot of the results were evaluated to have low level of evidence, making it difficult to draw clear conclusions. In the result reporting adverse effects, no serious outcome of adverse event was confirmed. Acupuncture and conventional medicine for chronic neck pain have similar effectiveness on pain and disability when compared solely between the two of them. When acupuncture was added onto conventional treatment it relieved pain better, and electroacupuncture relieved pain even more. It is difficult to draw conclusion because the included studies have a high risk of bias and imprecision. Therefore better designed large-scale studies are needed in the future.  
  Address dagger Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul, Republic of Korea  
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  Notes PMID:29121797 Approved no  
  Call Number OCOM @ refbase @ Serial 2943  
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Author Zhang, Y.; Lin, L.; Li, H.; Hu, Y.; Tian, L. url  doi
openurl 
  Title Effects of acupuncture on cancer-related fatigue: a meta-analysis Type of Study Journal Article
  Year 2018 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 26 Issue 2 Pages 415-425  
  Keywords Acupuncture; Cancer-related fatigue; Meta-analysis  
  Abstract PURPOSE: This study was designed to critically evaluate the effect of acupuncture on cancer-related fatigue (CRF). METHODS: Seven databases (Cochrane Library, Embase, Medline, Web of Science, CBM, Wanfang, and CNKI) were systematically reviewed from inception to November 2016 for randomized controlled trials (RCTs). Two reviewers critically and independently assessed the risk of bias using Cochrane Collaboration criteria and extracted correlated data using the designed form. All analyses were performed with Review Manager 5. RESULTS: Ten RCTs, including 1327 patients (acupuncture, 733; control, 594), meeting the inclusion criteria for the meta-analysis were identified. Acupuncture had a marked effect on fatigue in cancer patients, regardless of concurrent anti-cancer treatment, particularly among breast cancer patients. The meta-analysis also indicated that acupuncture could significantly mitigate CRF compared with sham acupuncture or usual care. Acupuncture for 20-30 min/session three times/week for two or three weeks, twice weekly for two weeks and weekly for six weeks, and weekly for six weeks had substantial effects on CRF. Six RCTs reported the occurrence of adverse events, whereas five reported none. The remaining study reported some manageable events, including spot bleeding and bruising. CONCLUSIONS: Acupuncture is effective for CRF management and should be recommended as a beneficial alternative therapy for CRF patients, particularly for breast cancer patients and those currently undergoing anti-cancer treatment.  
  Address The First Affiliated Hospital of Soochow University, P.O. Box 102, Suzhou, China. tianlisz@suda.edu.cn  
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  Notes PMID:29128952 Approved no  
  Call Number OCOM @ refbase @ Serial 2942  
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Author Chavez, L.M.; Huang, S.-S.; MacDonald, I.; Lin, J.-G.; Lee, Y.-C.; Chen, Y.-H. url  doi
openurl 
  Title Mechanisms of Acupuncture Therapy in Ischemic Stroke Rehabilitation: A Literature Review of Basic Studies Type of Study Journal Article
  Year 2017 Publication International Journal of Molecular Sciences Abbreviated Journal Int J Mol Sci  
  Volume 18 Issue 11 Pages  
  Keywords acupuncture; basic research; cerebral ischemia; rehabilitation; stroke  
  Abstract Acupuncture is recommended by the World Health Organization (WHO) as an alternative and complementary strategy for stroke treatment and for improving stroke care. Clinical trial and meta-analysis findings have demonstrated the efficacy of acupuncture in improving balance function, reducing spasticity, and increasing muscle strength and general well-being post-stroke. The mechanisms underlying the beneficial effects of acupuncture in stroke rehabilitation remain unclear. The aim of this study was to conduct a literature review, summarize the current known mechanisms in ischemic stroke rehabilitation through acupuncture and electroacupuncture (EA) therapy, and to detail the frequently used acupoints implicated in these effects. The evidence in this review indicates that five major different mechanisms are involved in the beneficial effects of acupuncture/EA on ischemic stroke rehabilitation: (1) Promotion of neurogenesis and cell proliferation in the central nervous system (CNS); (2) Regulation of cerebral blood flow in the ischemic area; (3) Anti-apoptosis in the ischemic area; (4) Regulation of neurochemicals; and, (5) Improvement of impaired long-term potentiation (LTP) and memory after stroke. The most frequently used acupoints in basic studies include Baihui (GV20), Zusanli (ST36), Quchi (LI11), Shuigou (GV26), Dazhui (GV14), and Hegu (LI4). Our findings show that acupuncture exerts a beneficial effect on ischemic stroke through modulation of different mechanisms originating in the CNS.  
  Address Department of Photonics and Communication Engineering, Asia University, Taichung 41354, Taiwan. yihungchen@mail.cmu.edu.tw  
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  Notes PMID:29143805; PMCID:PMC5713240 Approved no  
  Call Number OCOM @ refbase @ Serial 2941  
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Author Yang, X.; Liu, Y.; Liu, B.; He, L.; Liu, Z.; Yan, Y.; Liu, J.; Liu, B. url  doi
openurl 
  Title Factors related to acupuncture response in patients with chronic severe functional constipation: Secondary analysis of a randomized controlled trial Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 11 Pages e0187723  
  Keywords *Acupuncture Therapy; Constipation/*physiopathology/*therapy; Demography; Electroacupuncture; Female; Humans; Logistic Models; Male; Middle Aged; Treatment Outcome  
  Abstract BACKGROUND: Acupuncture has been demonstrated to be effective and safe for chronic severe functional constipation (CSFC). However, which patients with CSFC will have a better response to acupuncture remains unclear. OBJECTIVE: To explore factors related to acupuncture response in patients with CSFC. METHODS: We performed a secondary analysis of a previous multicenter randomized controlled trial consisting of a 2-week run-in period, 8-week treatment, and 12-week follow-up without treatment in which patients with CSFC were randomly allocated to an electroacupuncture group or a sham electroacupuncture group. Responders were defined as participants with an increase of at least one complete spontaneous bowel movement (CSBM) in week 20 compared with the baseline period. The CSBM responder rate in both groups was described, and the baseline characteristics of participants potentially related to acupuncture response were mainly analyzed using logistic regression analysis with bootstrapping techniques. RESULTS: A total of 1021 participants were analyzed in this study, of whom 516 (50.5%) were classified as responders. The CSBM responder rate in week 20 was significantly greater in the electroacupuncture group than in the sham electroacupuncture group (62.9% vs. 37.9%, respectively; P<0.001). Both age and comorbidity were negatively associated with clinical response: with every one-year increase in age, the likelihood of clinical response was reduced by 1.2% (OR 0.988, 95%CI 0.980 to 0.996; P = 0.005), and patients with comorbidities were approximately 42% less likely to respond to treatment (OR 0.581, 95%CI 0.248 to 0.914; P = 0.001). CONCLUSION: CSFC patients with increasing age and comorbidity may be less likely to respond to acupuncture. These findings contribute to guiding clinical practice in terms of pretreatment patient selection. Further research is needed to confirm the association.  
  Address Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China  
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  Notes PMID:29166673; PMCID:PMC5699843 Approved no  
  Call Number OCOM @ refbase @ Serial 2940  
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Author Namazi, N.; Khodamoradi, K.; Larijani, B.; Ayati, M.H. url  doi
openurl 
  Title Is laser acupuncture an effective complementary therapy for obesity management? A systematic review of clinical trials Type of Study Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 452-459  
  Keywords Acupuncture Therapy/*methods; Adult; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Laser Therapy/*methods; Male; Obesity/surgery/*therapy; Obesity Management/*methods; *Weight Loss; appetite; fat accumulation; laser acupuncture; obesity  
  Abstract BACKGROUND: Complementary therapies may increase the success rate of weight loss via a calorie-restricted diet. Acupuncture is a popular complementary therapy for obesity management. To our knowledge, no studies have summarised the effects of laser acupuncture (LA) on obesity. OBJECTIVE: To evaluate the efficacy of LA, in particular with respect to its impact on anthropometric features and appetite in obese adults, by conducting a systematic review of previous clinical trials. METHODS: We searched PubMed/Medline, Scopus, Web of Science, the Cochrane Library, Embase and Google Scholar electronic databases for papers published through October 2016. All clinical trials in English containing either anthropometric indices or appetite parameters were included. Two reviewers independently examined studies based on a predefined form for data extraction and the Jadad scale for quality assessment in order to minimise bias throughout the evaluation. RESULTS: After screening the papers, seven clinical trials met the criteria and were included in the systematic review. Positive effects of LA therapy were seen in body weight (n=3), body mass index (n=5), waist circumference (n=4), hip circumference (n=3), waist to hip ratio (n=4) and % fat mass (n=3). Appetite parameters were reported in one study, which showed that LA can reduce appetite and increase the sensation of feeling full. CONCLUSION: Although some studies have indicated beneficial effects for LA on obesity, the lack of evidence with high methodological quality made it impossible to reach a definitive conclusion about the efficacy of LA for obesity management. Further high-quality, randomised, sham-controlled clinical trials with a larger sample size are needed to shed light on the efficacy of LA for obesity management and weight maintenance.  
  Address School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran  
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  Notes PMID:29074473 Approved no  
  Call Number OCOM @ refbase @ Serial 2939  
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Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
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  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2938  
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Author Stein, D.J. url  doi
openurl 
  Title Massage Acupuncture, Moxibustion, and Other Forms of Complementary and Alternative Medicine in Inflammatory Bowel Disease Type of Study Journal Article
  Year 2017 Publication Gastroenterology Clinics of North America Abbreviated Journal Gastroenterol Clin North Am  
  Volume 46 Issue 4 Pages 875-880  
  Keywords Acupuncture; Complementary and alternative therapy; Crohn disease; Massage; Moxibustion; Ulcerative colitis  
  Abstract Complementary and alternative medicine is frequently used by inflammatory bowel disease (IBD) patients; most common are massage, acupuncture, and moxibustion therapy. Massage therapy is poorly studied in IBD patients; therefore, its benefits remain unknown. Acupuncture and moxibustion therapy have been shown to improve inflammation and symptoms in animal and human studies. However, current clinical trials of acupuncture and moxibustion are of insufficient quality to recommend them as alternative therapy. Nonetheless, because these therapies seem generally to be safe, they may have a role as complementary to conventional therapy.  
  Address Division of Gastroenterology and Hepatology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address: dstein@mcw.edu  
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  Notes PMID:29173528 Approved no  
  Call Number OCOM @ refbase @ Serial 2937  
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