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Author (up) Huang, M. I.; Nir, Y.; Chen, B.; Schnyer, R.; Manber, R. url  openurl
  Title A randomized controlled pilot study of acupuncture for postmenopausal hot flashes: effect on nocturnal hot flashes and sleep quality Type of Study RCT
  Year 2006 Publication Fertility and sterility Abbreviated Journal Fertil Steril  
  Volume 86 Issue 3 Pages 700-710  
  Keywords Acu Versus Sham; Acupuncture; AcuTrials; Hot Flashes; Manualized Acupuncture Protocol; Non Penetrating Sham, Mechanical; Perimenopause; Pilot Study; Postmenopause; RCT; Sham Acupoint Control; Sham Control; Sleep Quality; TCM Acupuncture Style; Traditional Diagnosis Based Point Selection; Women's Health; Restricted Modalities, Acupuncture Only  
  Abstract OBJECTIVE: To assess the effectiveness of acupuncture on postmenopausal nocturnal hot flashes and sleep. DESIGN: Prospective randomized placebo-controlled study. SETTING: Stanford University School of Medicine and private acupuncture offices. INTERVENTION(S): Active or placebo acupuncture was administered for nine sessions over seven weeks. MAIN OUTCOME MEASURE(S): Severity and frequency of nocturnal hot flashes from daily diaries and Pittsburgh Sleep Quality Index (PSQI). PATIENT(S): Twenty-nine postmenopausal women experiencing at least seven moderate to severe hot flashes daily, with E(2) <18 pg/mL and FSH 30.0-110.0 IU/L. RESULT(S): Nocturnal hot-flash severity significantly decreased in the active acupuncture group (28%) compared with the placebo group (6%), P=.017. The frequency of nocturnal hot flashes also decreased in the active group (47%, P=.001), though it was not significantly different from the placebo group (24%, P=.170; effect size = 0.65). Treatment did not differentially influence sleep; however, correlations between improvements in PSQI and reductions in nocturnal hot flash severity and frequency were significant (P<.026). CONCLUSION(S): Acupuncture significantly reduced the severity of nocturnal hot flashes compared with placebo. Given the strength of correlations between improvements in sleep and reductions in nocturnal hot flashes, further exploration is merited  
  Address Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA  
  Language Number of Treatments 9  
  Treatment Follow-up 4 Weeks Frequency >1/WK Number of Participants 29  
  Time in Treatment 7 Weeks Condition Hot Flashes
  Disease Category Climacteric OCSI Score 83  
  Notes Approved no  
  Call Number Serial 476  
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