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Author (up) Jimin Park; Hyun Soo Kim; Seung Min Lee; Kanghyun Yoon; Woo-shik Kim; Jong Shin Woo; Sanghoon Lee; Jin-Bae Kim; Weon Kim url  doi
  Title Acupuncture Antiarrhythmic Effects on Drug Refractory Persistent Atrial Fibrillation: Study Protocol for a Randomized, Controlled Trial Type of Study Journal Article
  Year 2015 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evid Based Complement Altern Med  
  Volume Issue Pages 1-6  
  Keywords Acupuncture -- Methods; Atrial Fibrillation -- Prevention and Control; Human; Randomized Controlled Trials; Prospective Studies; Random Assignment; Atrial Fibrillation -- Drug Therapy; Antiarrhythmia Agents -- Therapeutic Use; Echocardiography, Transesophageal; Multicenter Studies; South Korea; Risk Assessment; Electrocardiography; Sample Size; Descriptive Statistics; T-Tests; Mann-Whitney U Test; Chi Square Test; Fisher's Exact Test; Kaplan-Meier Estimator; Cox Proportional Hazards Model; Regression; Data Analysis Software; Clinical Assessment Tools; Funding Source  
  Abstract Background. Atrial fibrillation (AF) is the most common form of arrhythmia. Several trials have suggested that acupuncture may prevent AF. However, the efficacy of acupuncture for AF prevention has not been well investigated. Therefore, we designed a prospective, two-parallel-armed, participant and assessor blinded, randomized, sham-controlled clinical trial to investigate acupuncture in persistent AF (ACU-AF). Methods. A total of 80 participants will be randomly assigned to active acupuncture or sham acupuncture groups in a 1 : 1 ratio. Both groups will take the same antiarrhythmic medication during the study period. Patients will receive 10 sessions of acupuncture treatment once a week for 10 weeks. The primary endpoint is AF recurrence rate. Secondary endpoints are left atrium (LA) and left atrial appendage (LAA) changes in function and volume, and inflammatory biomarker changes. Ethics. This study protocol was approved by the institutional review boards (IRBs) of Kyung Hee University Hospital (number 1335-04). This trial is registered with NCT02110537.  
  Address Division of Cardiology, Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea  
  Publisher Hindawi Limited
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 108824781. Language: English. Entry Date: 20170222. Revision Date: 20170222. Publication Type: journal article; pictorial; research; tables/charts; randomized controlled trial. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice. Grant Information: This study is supported by grants from the Korean Government(Ministry of Health) (no. HI13C0580).. NLM UID: 101215021. Approved no  
  Call Number OCOM @ refbase @ 108824781 Serial 2323  
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