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Author Li, P.; Qiu, T.; Qin, C.
Title Efficacy of Acupuncture for Bell's Palsy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Type of Study Systematic Review
Year 2015 Publication PloS one Abbreviated Journal PLoS One
Volume 10 Issue 5 Pages e0121880
Keywords Systematic Review; Cranial Nerve Diseases; Bell Palsy; Bell's Palsy; Acupuncture
Abstract Acupuncture has emerged as an alternative therapy for Bell's palsy in both adults and children. However, the use of acupuncture is controversial. We conducted a systematic review and meta-analysis to assess the efficacy of acupuncture for Bell's palsy. We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials, irrespective of any language restrictions. Randomized controlled trials comparing acupuncture with other therapies for Bell's palsy in adults or children were included. Fourteen randomized controlled trials involving 1541 individuals were included in this meta-analysis. Significant association was observed in acupuncture with a higher effective response rate for Bell's palsy (relative risk, 1.14; 95% confidence interval, 1.04-1.25; P = 0.005) but there was a heterogeneity among the studies (I2 = 87%). An assessment of the included studies revealed a high risk of bias in methodological quality. An evaluation of the incidence of complications was not available, owing to incomplete data. Acupuncture seems to be an effective therapy for Bell's palsy, but there was insufficient evidence to support the efficacy and safety of acupuncture. However, the results should be interpreted cautiously, because of the poor quality and heterogeneity of the included studies.
Address Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:25974022; PMCID:PMC4431843 Approved no
Call Number OCOM @ refbase @ Serial 2046
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Author Li, P.; Qiu, T.; Qin, C.
Title Efficacy of Acupuncture for Bell's Palsy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Type of Study Journal Article
Year 2015 Publication PLoS One Abbreviated Journal
Volume 10 Issue 5 Pages e0121880
Keywords
Abstract Acupuncture has emerged as an alternative therapy for Bell's palsy in both adults and children. However, the use of acupuncture is controversial. We conducted a systematic review and meta-analysis to assess the efficacy of acupuncture for Bell's palsy. We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials, irrespective of any language restrictions. Randomized controlled trials comparing acupuncture with other therapies for Bell's palsy in adults or children were included. Fourteen randomized controlled trials involving 1541 individuals were included in this meta-analysis. Significant association was observed in acupuncture with a higher effective response rate for Bell's palsy (relative risk, 1.14; 95% confidence interval, 1.04-1.25; P = 0.005) but there was a heterogeneity among the studies (I2 = 87%). An assessment of the included studies revealed a high risk of bias in methodological quality. An evaluation of the incidence of complications was not available, owing to incomplete data. Acupuncture seems to be an effective therapy for Bell's palsy, but there was insufficient evidence to support the efficacy and safety of acupuncture. However, the results should be interpreted cautiously, because of the poor quality and heterogeneity of the included studies.
Address Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China
Publisher
Language Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category New Articles to Enter OCSI Score
Notes Date of Input: 6/23/2015; Date Modified: 7/7/2015; Availability: --In File--; Priority: Normal; Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China; eng; Web: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=25974022 Approved no
Call Number OCOM @ refbase @ Serial 1608
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Author Chen, N.; Zhou, M.; He, L.; Zhou, D.; Li, N.
Title Acupuncture for Bell's palsy Type of Study Systematic Review
Year 2010 Publication Cochrane database of systematic reviews (Online) Abbreviated Journal Cochrane Database Syst Rev
Volume Issue 8 Pages -
Keywords AcuTrials; Systematic Review; Cranial Nerve Diseases; Bell Palsy; Acupuncture; Nervous System Diseases; Facial Paralysis; Bell's Palsy
Abstract BACKGROUND: Bell's palsy or idiopathic facial palsy is an acute facial paralysis due to inflammation of the facial nerve. A number of studies published in China have suggested acupuncture is beneficial for facial palsy. OBJECTIVES: The objective of this review was to examine the efficacy of acupuncture in hastening recovery and reducing long-term morbidity from Bell's palsy. SEARCH STRATEGY: We updated the searches of the Cochrane Neuromuscular Disease Group Trials Specialized Register (24 May 2010), The Cochrane Central Register of Controlled Trials (CENTRAL) (Issue 2, 2010), MEDLINE (January 1966 to May 2010), EMBASE (January 1980 to May 2010), AMED (January 1985 to May 2010), LILACS (from January 1982 to May 2010) and the Chinese Biomedical Retrieval System (January 1978 to May 2010) for randomised controlled trials using 'Bell's palsy' and its synonyms, 'idiopathic facial paralysis' or 'facial palsy' as well as search terms including 'acupuncture'. Chinese journals in which we thought we might find randomised controlled trials relevant to our study were handsearched. We reviewed the bibliographies of the randomised trials and contacted the authors and known experts in the field to identify additional published or unpublished data. SELECTION CRITERIA: We included all randomised controlled trials involving acupuncture by needle insertion in the treatment of Bell's palsy irrespective of any language restrictions. DATA COLLECTION AND ANALYSIS: Two review authors identified potential articles from the literature search, extracted data and assessed quality of each trial independently. All disagreements were resolved by discussion between the review authors. MAIN RESULTS: The literature search and handsearching identified 49 potentially relevant articles. Of these, six RCTs were included involving 537 participants with Bell's palsy. Two more possible trials were identified in the update than the previous version of this systematic review, but both were excluded because they were not real RCTs. Of the six included trials, five used acupuncture while the other one used acupuncture combined with drugs. No trial reported on the outcomes specified for this review. Harmful side effects were not reported in any of the trials. Poor quality caused by flaws in study design or reporting (including uncertain method of randomisation, allocation concealment and blinding) and clinical differences between trials prevented reliable conclusions about the efficacy of acupuncture. AUTHORS' CONCLUSIONS: The quality of the included trials was inadequate to allow any conclusion about the efficacy of acupuncture. More research with high quality trials is needed.
Address Department of Neurology, West China Hospital, Sichuan University, Wai Nan Guo Xue Xiang #37, Chengdu, Sichuan, China, 610041.
Publisher
Language Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition Bell Palsy
Disease Category Cranial Nerve Diseases OCSI Score
Notes Approved yes
Call Number Serial 145
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Author Zhou, M.; He, L.; Zhou, D.; Wu, B.; Li, N.; Kong, S.; Zhang, D.; Li, Q.; Yang, J.; Zhang, X.
Title Acupuncture for Bell's Palsy Type of Study Systematic Review
Year 2009 Publication Abbreviated Journal J Altern Complement Med
Volume Issue Pages -
Keywords Acupuncture; AcuTrials; Bell Palsy; Facial Paralysis; Systematic Review; Cranial Nerve Diseases; Nervous System Diseases
Abstract Abstract Objectives: The objectives of this study were to examine the efficacy of acupuncture in hastening recovery and reducing long-term morbidity from Bell's palsy. Methods: We searched the Cochrane Neuromuscular Disease Group Trials Register, MEDLINE((R)) (January 1966-April 2006), EMBASE (January 1980-April 2006), LILACS (January 1982-April 2006), and the Chinese Biomedical Retrieval System (January 1978-April 2006) for randomized controlled trials using “Bell's palsy” and its synonyms, “idiopathic facial paralysis” or “facial palsy” as well as search terms including “acupuncture.” Chinese journals in which we thought we might find randomized controlled trials or controlled clinical trials relevant to our study were hand searched. We reviewed the bibliographies of the randomized trials and contacted the authors and known experts in the field to identify additional published or unpublished data. We included all randomized or quasi-randomized controlled trials involving acupuncture in the treatment of Bell's palsy, irrespective of any language restrictions. Two review authors identified potential articles from the literature search and extracted data independently using a data extraction form. The assessment of methodological quality included allocation concealment, patient blinding, differences at baseline of the experimental groups, and completeness of follow-up. Two (2) review authors assessed quality independently. All disagreements were resolved by discussion between the review authors. Results: Six (6) studies including a total of 537 participants met the inclusion criteria. Five (5) of them used acupuncture while another one used acupuncture combined with drugs. No trials reported on the outcomes specified for this review. Harmful side-effects were not reported in any of the trials. Flaws in study design or reporting (particularly uncertain allocation concealment and substantial loss to follow-up) and clinical differences between trials prevented conclusions about the efficacy of acupuncture. Conclusions: The quality of the included trials was inadequate to allow any conclusion about the efficacy of acupuncture. More research with high-quality trials is needed
Address Neurology Department, West China Hospital, Sichuan University , Chengdu, China
Publisher
Language Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition Bell Palsy
Disease Category Cranial Nerve Diseases OCSI Score
Notes Approved no
Call Number Serial 1483
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Author Kim, J. I.; Lee, M. S.; Choi, T. Y.; Lee, H.; Kwon, H. J.
Title Acupuncture for Bell's palsy: A systematic review and meta-analysis Type of Study Systematic Review
Year 2012 Publication Chinese journal of integrative medicine Abbreviated Journal Chin J Integr Med
Volume 18 Issue 1 Pages 48-55
Keywords Systematic Review; Cranial Nerve Diseases; Bell Palsy; AcuTrials; Acupuncture
Abstract OBJECTIVE: To assess the clinical evidence for and against acupuncture as a treatment for Bell's palsy. METHODS: We conducted a literature search of 15 databases from their inception to December 2010 without language restrictions. We included all randomized clinical trials (RCTs) regardless of their controls. Methodological quality was evaluated using the Cochrane risk of bias assessment tool. RESULTS: Of the 3 474 articles, only eight RCTs met our inclusion criteria. Four RCTs tested the effects of acupuncture against drug therapy on disease response rate. The meta-analysis of these data showed significant improvements in the acupuncture group [n=463, risk ratio (RR)=1.07, 95% CI: 1.02 to 1.13; P=0.006, I(2)=0%]. Six RCTs tested the effects of acupuncture plus drug therapy versus drug therapy alone. The meta-analysis of this set of RCTs also showed the favorable effects of acupuncture on disease response rate (n=512, RR=1.11, 95% CI: 1.05 to 1.17; P=0.001, I(2)=13%). CONCLUSIONS: The evidence supporting the effectiveness of acupuncture for treating Bell's palsy is limited. The number and quality of trials are too low to form firm conclusions. Further rigorous RCTs are warranted but need to overcome the many limitations of the current evidence.
Address Department of Acupuncture and Moxibustion, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Publisher
Language Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition Bell Palsy
Disease Category Cranial Nerve Diseases OCSI Score
Notes Approved no
Call Number Serial 571
Permanent link to this record
 

 
Author He, L.; Zhou, D.; Wu, B.; Li, N.; Zhou, M.
Title Acupuncture for Bell's palsy Type of Study Systematic Review
Year 2004 Publication Abbreviated Journal Cochrane Database Syst Rev
Volume 1 Issue Pages CD002914-
Keywords Acupuncture; AcuTrials; Bell Palsy; Facial Paralysis; Meta-Analysis; Systematic Review; Cranial Nerve Diseases; Nervous System Diseases
Abstract BACKGROUND: Bell's palsy or idiopathic facial palsy is an acute facial paralysis due to inflammation of the facial nerve. A number of studies published in China have suggested acupuncture is beneficial for facial palsy. OBJECTIVES: The objective of this review was to examine the efficacy of acupuncture in hastening recovery and reducing long-term morbidity from Bell's palsy. SEARCH STRATEGY: We searched the Cochrane Neuromuscular Disease Group Register, MEDLINE (January 1966 to December 2002), EMBASE (January 1980 to December 2002), LILACS (from January 1982 to December 2002) and the Chinese Biomedical Retrieval System (January 1978 to December 2002) for randomised controlled trials using 'Bell's palsy' and its synonyms, 'idiopathic facial paralysis' or 'facial palsy' as well as search terms including 'acupuncture'. Chinese journals in which we thought we might find randomised controlled trials or controlled clinical trials relevant to our study were handsearched. We reviewed the bibliographies of the randomised trials and contacted the authors and known experts in the field to identify additional published or unpublished data. SELECTION CRITERIA: We included all randomised or quasi-randomised controlled trials involving acupuncture in the treatment of Bell's palsy irrespective of any language restrictions. DATA COLLECTION AND ANALYSIS: Two reviewers identified potential articles from the literature search and extracted data independently using a data extraction form. The assessment of methodological quality included allocation concealment, patient blinding, differences at baseline of the experimental groups and completeness of follow-up. Two reviewers assessed quality independently. All disagreements were resolved by discussion between the reviewers. MAIN RESULTS: Three studies including a total of 238 patients met the inclusion criteria. Two of them used acupuncture while the third used acupuncture combined with drugs. No trials reported on the outcomes specified for this review.Three included studies showed that the therapeutic effect of acupuncture alone was superior to that of medication or that acupuncture combined with medication was better than medication alone. Harmful side-effects were not reported in any of the trials. Flaws in study design or reporting (particularly uncertain allocation concealment and substantial loss to follow-up) and clinical differences between trials prevented a meta-analysis. REVIEWER'S CONCLUSIONS: The quality of the included trials was inadequate to allow any conclusion about the efficacy of acupuncture. More research with high quality trials is needed
Address Department of Neurology, First University Hospital, West China University of Medical Sciences, Chengdu 610041, Sichuan, CHINA
Publisher
Language Number of Treatments
Treatment Follow-up N/A Frequency N/A Number of Participants
Time in Treatment N/A Condition Bell Palsy
Disease Category Cranial Nerve Diseases OCSI Score
Notes Approved no
Call Number Serial 445
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