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Author (up) Huang, M. I.; Nir, Y.; Chen, B.; Schnyer, R.; Manber, R. url  openurl
  Title A randomized controlled pilot study of acupuncture for postmenopausal hot flashes: effect on nocturnal hot flashes and sleep quality Type of Study RCT
  Year 2006 Publication Fertility and sterility Abbreviated Journal Fertil Steril  
  Volume 86 Issue 3 Pages 700-710  
  Keywords Acu Versus Sham; Acupuncture; AcuTrials; Hot Flashes; Manualized Acupuncture Protocol; Non Penetrating Sham, Mechanical; Perimenopause; Pilot Study; Postmenopause; RCT; Sham Acupoint Control; Sham Control; Sleep Quality; TCM Acupuncture Style; Traditional Diagnosis Based Point Selection; Women's Health; Restricted Modalities, Acupuncture Only  
  Abstract OBJECTIVE: To assess the effectiveness of acupuncture on postmenopausal nocturnal hot flashes and sleep. DESIGN: Prospective randomized placebo-controlled study. SETTING: Stanford University School of Medicine and private acupuncture offices. INTERVENTION(S): Active or placebo acupuncture was administered for nine sessions over seven weeks. MAIN OUTCOME MEASURE(S): Severity and frequency of nocturnal hot flashes from daily diaries and Pittsburgh Sleep Quality Index (PSQI). PATIENT(S): Twenty-nine postmenopausal women experiencing at least seven moderate to severe hot flashes daily, with E(2) <18 pg/mL and FSH 30.0-110.0 IU/L. RESULT(S): Nocturnal hot-flash severity significantly decreased in the active acupuncture group (28%) compared with the placebo group (6%), P=.017. The frequency of nocturnal hot flashes also decreased in the active group (47%, P=.001), though it was not significantly different from the placebo group (24%, P=.170; effect size = 0.65). Treatment did not differentially influence sleep; however, correlations between improvements in PSQI and reductions in nocturnal hot flash severity and frequency were significant (P<.026). CONCLUSION(S): Acupuncture significantly reduced the severity of nocturnal hot flashes compared with placebo. Given the strength of correlations between improvements in sleep and reductions in nocturnal hot flashes, further exploration is merited  
  Address Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA  
  Publisher
  Language Number of Treatments 9  
  Treatment Follow-up 4 Weeks Frequency >1/WK Number of Participants 29  
  Time in Treatment 7 Weeks Condition Hot Flashes
  Disease Category Climacteric OCSI Score 83  
  Notes Approved no  
  Call Number Serial 476  
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Author (up) Nir, Y.; Huang, M. I.; Schnyer, R.; Chen, B.; Manber, R. url  openurl
  Title Acupuncture for postmenopausal hot flashes Type of Study RCT
  Year 2006 Publication Abbreviated Journal Maturitas  
  Volume Issue Pages -  
  Keywords Acu Versus Sham; Acupuncture; AcuTrials; Hot Flashes; Semi-Individualized Acupuncture Protocol; Menopause; Non Penetrating Sham, Mechanical; Pilot Study; RCT; Sham Acupoint Control; Sham Control; TCM Acupuncture Style; Traditional Diagnosis Based Point Selection; Women's Health; Climacteric; Postmenopause; Restricted Modalities, Acupuncture Only  
  Abstract OBJECTIVE: To determine whether individually tailored acupuncture is an effective treatment option for reducing postmenopausal hot flashes and improving quality of life. METHODS: In a randomized, placebo-controlled pilot study, 29 postmenopausal participants averaging at least seven moderate to severe hot flashes per 24h, with a baseline estradiol concentration of less than 50pg/mL and a normal TSH level, were randomized to receive 7 weeks (nine treatment sessions) of either active acupuncture or placebo acupuncture (placebo needles that did not penetrate the skin at sham acupuncture points). Participants recorded hot flashes in logs that were reported daily. Global indices of the severity and frequency of hot flashes were derived from the participants' daily logs. RESULTS: Participants receiving the active treatment had a greater reduction in hot flash severity (24.5+/-30.7%) compared to those receiving placebo (4.4+/-17.1%, P=0.042). Within group repeated measures analyses of variance revealed a significant reduction in hot flash severity in the active (P=0.042), but not in the placebo treatment group (P=0.15). Although there was no significant group difference in the reduction of hot flash frequency between the active (42.4+/-32.2%) and placebo groups (32.0+/-26.5%; P>/=0.352), within group repeated measures analyses of variance revealed that the reduction was statistically significant in both groups (P</=0.001). CONCLUSIONS: Standardized, individually tailored acupuncture treatment was associated with significantly greater decrease in the severity, but not the frequency, of hot flashes, in symptomatic postmenopausal women when compared to placebo acupuncture of equal duration. Future, larger scale, studies are needed  
  Address Stanford University School of Medicine, United States  
  Publisher
  Language Number of Treatments 9  
  Treatment Follow-up 5 Weeks Frequency >1/WK Number of Participants 29  
  Time in Treatment 7 Weeks Condition Hot Flashes
  Disease Category Climacteric OCSI Score 70  
  Notes Approved no  
  Call Number Serial 913  
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