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Author (up) Grant, S.; Kandrack, R.; Motala, A.; Shanman, R.; Booth, M.; Miles, J.; Sorbero, M.; Hempel, S. url  doi
  Title Acupuncture for substance use disorders: A systematic review and meta-analysis Type of Study Systematic Review
  Year 2016 Publication Drug and Alcohol Dependence Abbreviated Journal Drug Alcohol Depend  
  Volume 163 Issue Pages 1-15  
  Keywords AcuTrials; Systematic Review; Substance-Related Disorders; Drug Addiction; Substance Abuse; Acupuncture  
  Abstract BACKGROUND: This systematic review aims to estimate the effects of acupuncture for adults with substance use disorders (SUDs). METHODS: We searched 7 electronic databases and bibliographies of previous studies to identify eligible randomized trials. Two independent reviewers screened citations, extracted data, and assessed risks of bias. We performed random effects meta-analyses. We assessed quality of evidence using the GRADE approach. RESULTS: We included 41 studies with 5,227 participants. No significant differences were observed between acupuncture and comparators (passive controls, sham acupuncture, treatment as usual, and active interventions) at post-intervention for relapse (SMD -0.12; 95%CI -0.46 to 0.22; 10 RCTs), frequency of substance use (SMD -0.27; -2.67 to 2.13; 2 RCTs), quantity of substance use (SMD 0.01; -0.40 to 0.43; 3 RCTs), and treatment dropout (OR 0.82; 0.63 to 1.09; 22 RCTs). We identified a significant difference in favor of acupuncture versus comparators for withdrawal/craving at post-intervention (SMD -0.57, -0.93 to -0.20; 20 RCTs), but we identified evidence of publication bias. We also identified a significant difference in favor of acupuncture versus comparators for anxiety at post-intervention (SMD -0.74, -1.15 to -0.33; 6 RCTs). Results for withdrawal/craving and anxiety symptoms were not significant at longer follow-up. Safety data (12 RCTs) suggests little risk of serious adverse events, though participants may experience slight bleeding or pain at needle insertion sites. CONCLUSIONS: Available evidence suggests no consistent differences between acupuncture and comparators for substance use. Results in favor of acupuncture for withdrawal/craving and anxiety symptoms are limited by low quality bodies of evidence.  
  Address RAND, 1776 Main Street, P.O. Box 2138, Santa Monica, CA 90407-2138, USA  
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition Substance-Related Disorders
  Disease Category Substance-Related Disorders OCSI Score  
  Notes PMID:26968093 Approved yes  
  Call Number OCOM @ refbase @ Serial 2067  
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