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Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2955
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2914
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2873
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2832
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2791
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2750
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2686
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2645
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2627
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2586
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2545
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2504
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2018 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume 19 Issue 1 Pages 39-58
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2463
Permanent link to this record
 

 
Author Grant, S.; Colaiaco, B.; Motala, A.; Shanman, R.; Sorbero, M.; Hempel, S.
Title Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis Type of Study Journal Article
Year 2017 Publication Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD) Abbreviated Journal J Trauma Dissociation
Volume Issue Pages 1-20
Keywords Alternative medicine; complementary medicine; meta-analysis; posttraumatic stress disorder; systematic review
Abstract Acupuncture has been suggested as a treatment for posttraumatic stress disorder (PTSD), yet its clinical effects are unclear. This review aims to estimate effects of acupuncture on PTSD symptoms, depressive symptoms, anxiety symptoms, and sleep quality for adults with PTSD. We searched 10 databases in January 2016 to identify eligible randomized controlled trials (RCTs). We performed random effects meta-analyses and examined quality of the body of evidence (QoE) using the GRADE approach to rate confidence in meta-analytic effect estimates. Seven RCTs with 709 participants met inclusion criteria. We identified very low QoE indicating significant differences favoring acupuncture (versus any comparator) at post-intervention on PTSD symptoms (standardized mean difference [SMD] = -0.80, 95% confidence interval [CI] [-1.59, -0.01], 6 RCTs), and low QoE at longer follow-up on PTSD (SMD = -0.46, 95% CI [-0.85, -0.06], 4 RCTs) and depressive symptoms (SMD = -0.56; 95% CI [-0.88, -0.23], 4 RCTs). No significant differences were observed between acupuncture and comparators at post-intervention for depressive symptoms (SMD = -0.58, 95% CI [-1.18, 0.01], 6 RCTs, very low QoE), anxiety symptoms (SMD = -0.82, 95% CI [-2.16, 0.53], 4 RCTs, very low QoE), and sleep quality (SMD = -0.46, 95% CI [-3.95, 3.03], 2 RCTs, low QoE). Safety data (7 RCTs) suggest little risk of serious adverse events, though some participants experienced minor/moderate pain, superficial bleeding, and hematoma at needle insertion sites. To increase confidence in findings, sufficiently powered replication trials are needed that measure all relevant clinical outcomes and dedicate study resources to minimizing participant attrition.
Address a RAND Corporation , Santa Monica , California , USA
Publisher
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:28151093 Approved no
Call Number OCOM @ refbase @ Serial 2214
Permanent link to this record