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Author (up) Bokmand, S.; Flyger, H.
Title Acupuncture relieves menopausal discomfort in breast cancer patients: a prospective, double blinded, randomized study Type of Study RCT
Year 2013 Publication Breast (Edinburgh, Scotland) Abbreviated Journal Breast
Volume 22 Issue 3 Pages 320-323
Keywords AcuTrials; Climacteric; Menopause; RCT; Acu Versus > 1 Control; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Sham Control; Penetrating Sham; Superficial Needling Depth; Near Verum Acupoint Control; Breast Cancer; Neoplasms; Women's Health; Postmenopause; Hot Flashes; Cancer
Abstract BACKGROUND: This study evaluates the effect of acupuncture on hot flashes and disturbed night sleep in patients treated for breast cancer. The effect of acupuncture was tested against a sham-acupuncture group and a no-treatment control group. Plasma estradiol was measured to rule out this as cause of effect. Side effects of the treatment were registered. METHODS: We randomized 94 women into the study: 31 had acupuncture, 29 had sham acupuncture and 34 had no treatment. FINDINGS: In the acupuncture group, 16 patients (52%) experienced a significant effect on hot flashes compared with seven patients (24%) in the sham group (p < 0.05). The effect came after the second acupuncture session and lasted for at least 12 weeks after last treatment. A statistically significant positive effect was seen on sleep in the acupuncture group compared with the sham-acupuncture and no-treatment groups. The effect was not correlated with increased levels of plasma estradiol. No side effects of acupuncture were registered. INTERPRETATION: We find that acupuncture significantly relieves hot flashes and sleep disturbances and is a good and safe treatment in women treated for breast cancer.
Address Department of Breast Surgery, Vejle Hospital, Denmark. sbok0003@heh.regionh.dk
Language Number of Treatments 5
Treatment Follow-up 12 Weeks Frequency 1/WK Number of Participants 94
Time in Treatment 5 Weeks Condition Menopause
Disease Category Climacteric OCSI Score
Notes Approved no
Call Number Serial 82
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