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Author (up) Manber, R.; Schnyer, R. N.; Allen, J. J.; Rush, A. J.; Blasey, C. M. url  openurl
  Title Acupuncture: a promising treatment for depression during pregnancy Type of Study RCT
  Year 2004 Publication Abbreviated Journal J Affect Disord  
  Volume 83 Issue 1 Pages 89-95  
  Keywords CAM Control; Acu Versus > 1 Control; Acupuncture; AcuTrials; Depression; Depressive Disorder; Individualized Acupuncture Protocol; Penetrating Sham; Massage; Non Specific Acupoint Control; RCT; Restricted Modalities, Acupuncture Only; Sham Control; Standard Needling Depth; TCM Acupuncture Style; Traditional Diagnosis Based Point Selection; Women's Health; Depression, Postpartum; Pregnancy Complications  
  Abstract BACKGROUND: Few medically acceptable treatments for depression during pregnancy are available. The aim of this randomized controlled pilot study was to determine whether acupuncture holds promise as a treatment for depression during pregnancy. METHODS: Sixty-one pregnant women with major depressive disorder and a 17-item Hamilton Rating Scale for Depression (HRSD(17)) score >/=14 were randomly assigned to one of three treatments, delivered over 8 weeks: an active acupuncture (SPEC, N=20), an active control acupuncture (NSPEC, N=21), and massage (MSSG, N=20). Acupuncture treatments were standardized, but individually tailored, and were provided in a double-blind fashion. Responders to acute phase treatment (HRSD(17) score<14 and >/=50% reduction from baseline) continued the treatment they were initially randomized to until 10 weeks postpartum. RESULTS: Response rates at the end of the acute phase were statistically significantly higher for SPEC (69%) than for MSSG (32%), with an intermediate NSPEC response rate (47%). The SPEC group also exhibited a significantly higher average rate of reduction in BDI scores from baseline to the end of the first month of treatment than the MSSG group. Responders to the acute phase of all treatments combined had significantly lower depression scores at 10 weeks postpartum than nonresponders. LIMITATIONS: Generalizability is limited by the small sample and its relative homogeneity. CONCLUSION: Acupuncture holds promise for the treatment of depression during pregnancy  
  Address Department of Psychiatry and Behavioral Sciences, Stanford University. 401, Quarry Rd., Stanford, CA 94305, United States  
  Publisher
  Language Number of Treatments 24  
  Treatment Follow-up 2 Weeks Frequency >1/WK Number of Participants 61  
  Time in Treatment 16 Weeks Condition Depression, Postpartum
  Disease Category Pregnancy Complications OCSI Score 68  
  Notes Approved no  
  Call Number Serial 813  
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