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Author Liu, B.-P.; Wang, Y.-T.; Chen, S.-da
Title Effect of acupuncture on clinical symptoms and laboratory indicators for chronic prostatitis/chronic pelvic pain syndrome: a systematic review and meta-analysis Type of Study Journal Article
Year 2016 Publication International Urology and Nephrology Abbreviated Journal Int Urol Nephrol
Volume 48 Issue 12 Pages 1977-1991
Keywords Acupuncture; Chronic pelvic pain syndrome; Chronic prostatitis; Meta-analysis; Review
Abstract OBJECTIVES: To systematically review the efficacy and safety of acupuncture for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). METHODS: PubMed, Cochrane library Central, Web of Science, Wang-fang Database, and CNKI were searched from their inception to June 30, 2016. Data of acupuncture for CP/CPPS following randomized controlled trials (RCTs) was included. The data were analyzed using the Cochrane Collaboration Review Manager. The primary data were the National Institute of Health-Chronic Prostatitis Index (NIH-CPSI) score at the end of follow-up. RESULTS: Ten RCTs were enrolled. Acupuncture was superior to the control in NIH-CPSI (MD -3.98, [95 % CI -5.78 to -2.19]; P < 0.0001) and response rate (RR 4.12, [95 % CI 1.67-10.18]; P = 0.002). Acupuncture was superior to sham acupuncture on NIH-CPSI, response rate, pain, urinary, and quality of life (QOL). Standard medication was inferior to acupuncture in terms of NIH-CPSI (MD -3.08, [95 % CI -5.57 to -0.60]; P = 0.02) and response rate (RR 2.03, [95 % CI 1.04-3.97]; P = 0.04), but standard medication was superior to acupuncture on improving urinary symptoms. There was no significant difference in the adverse events. Acupuncture/acupuncture plus standard medication significantly down-regulated IL-1beta compared with standard medication in prostatic fluid. CONCLUSION: Acupuncture treating CP/CPPS is effective and safe. The effects of acupuncture on NIH-CPSI, response rate, pain symptoms, and QOF were superior to the control, but standard medication significantly improved urinary symptoms compared with acupuncture. Acupuncture can decrease the IL-1beta in prostatic fluid for CP/CPPS.
Address The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China
Language English Number of Treatments
Treatment Follow-up Frequency Number of Participants
Time in Treatment Condition
Disease Category OCSI Score
Notes PMID:27590134 Approved no
Call Number OCOM @ refbase @ Serial 2205
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