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Author (up) Ntritsou, V.; Mavrommatis, C.; Kostoglou, C.; Dimitriadis, G.; Tziris, N.; Zagka, P.; Vasilakos, D. url  doi
openurl 
  Title Effect of perioperative electroacupuncture as an adjunctive therapy on postoperative analgesia with tramadol and ketamine in prostatectomy: a randomised sham-controlled single-blind trial Type of Study Journal Article
  Year 2014 Publication Acupuncture in Medicine Abbreviated Journal Acupuncture Med  
  Volume 32 Issue 3 Pages 215-222  
  Keywords Prostatectomy, Radical -- Methods; Perioperative Care; Postoperative Pain; Analgesia -- Methods; Combined Modality Therapy; Electroacupuncture -- Methods; Tramadol -- Administration and Dosage; Ketamine -- Administration and Dosage; Outcome Assessment; Human; Randomized Controlled Trials; Patient Satisfaction; Adverse Drug Event; Double-Blind Studies; Placebos; Descriptive Statistics; Random Assignment; McGill Pain Questionnaire; Questionnaires; State-Trait Anxiety Inventory; Male; Middle Age; Aged; Power Analysis; Chi Square Test; Confidence Intervals; Data Analysis Software; Summated Rating Scaling  
  Abstract Objectives: To study the analgesic effect of electroacupuncture (EA) as perioperative adjunctive therapy added to a systemic analgesic strategy (including tramadol and ketamine) for postoperative pain, opioid-related side effects and patient satisfaction. Methods: In a sham-controlled participant- and observer-blinded trial, 75 patients undergoing radical prostatectomy were randomly assigned to two groups: (1) EA (n=37; tramadol+ketamine +EA) and (2) control (n=38; tramadol+ketamine). EA (100 Hz frequency) was applied at LI4 bilaterally during the closure of the abdominal walls and EA (4 Hz) was applied at ST36 and LI4 bilaterally immediately after extubation. The control group had sham acupuncture without penetration or stimulation. The following outcomes were evaluated: postoperative pain using the Numerical Rating Scale (NRS) and McGill Scale (SFMPQ), mechanical pain thresholds using algometer application close to the wound, cortisol measurements, rescue analgesia, Spielberger State Trait Anxiety Inventory (STAI Y-6 item), patient satisfaction and opioid side effects. Results: Pain scores on the NRS and SFMPQ were significantly lower and electronic pressure algometer measurements were significantly higher in the EA group than in the control group (p<0.001) at all assessments. In the EA group a significant decrease in rescue analgesia was observed at 45 min (p<0.001) and a significant decrease in cortisol levels was also observed (p<0.05). Patients expressed satisfaction with the analgesia, especially in the EA group (p<0.01). Significant delays in the start of bowel movements were observed in the control group at 45 min (p<0.001) and 2 h (p<0.05). Conclusions: Adding EA perioperatively should be considered an option as part of a multimodal analgesic strategy.  
  Address Department of Anaesthesiology and Intensive Care, University Hospital of Thessaloniki “Ahepa”, Thessaloniki, Greece  
  Publisher BMJ Publishing Group
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 103977176. Language: English. Entry Date: 20140725. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Commentary: Usichenko T. I., Streitberger K. Perioperative acupuncture: why are we not using it? (ACUPUNCTURE MED) Jun2014; 32 (3): 212-214. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Instrumentation: State-Trait Anxiety Inventory (STAI) (Spielberger); Numeric Pain Rating Scale (NPRS); McGill Pain Questionnaire; Present Pain Intensity Scale (PPI). NLM UID: 9304117. Approved no  
  Call Number OCOM @ refbase @ 103977176 Serial 2365  
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Author (up) Ntritsou, V.; Mavrommatis, C.; Kostoglou, C.; Dimitriadis, G.; Tziris, N.; Zagka, P.; Vasilakos, D. url  doi
openurl 
  Title Effect of perioperative electroacupuncture as an adjunctive therapy on postoperative analgesia with tramadol and ketamine in prostatectomy: a randomised sham-controlled single-blind trial Type of Study RCT
  Year 2014 Publication Acupuncture in medicine : journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 32 Issue Pages 215-222  
  Keywords Anesthesia and Analgesia; Pain, Postoperative; RCT; Acu + Usual Care Versus Sham + Usual Care; Electroacupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Sham Control; Non Penetrating Sham, Electrical; Verum Acupoint Control; Pain, Perioperative  
  Abstract OBJECTIVES: To study the analgesic effect of electroacupuncture (EA) as perioperative adjunctive therapy added to a systemic analgesic strategy (including tramadol and ketamine) for postoperative pain, opioid-related side effects and patient satisfaction. METHODS: In a sham-controlled participant- and observer-blinded trial, 75 patients undergoing radical prostatectomy were randomly assigned to two groups: (1) EA (n=37; tramadol+ketamine+EA) and (2) control (n=38; tramadol+ketamine). EA (100 Hz frequency) was applied at LI4 bilaterally during the closure of the abdominal walls and EA (4 Hz) was applied at ST36 and LI4 bilaterally immediately after extubation. The control group had sham acupuncture without penetration or stimulation. The following outcomes were evaluated: postoperative pain using the Numerical Rating Scale (NRS) and McGill Scale (SFMPQ), mechanical pain thresholds using algometer application close to the wound, cortisol measurements, rescue analgesia, Spielberger State Trait Anxiety Inventory (STAI Y-6 item), patient satisfaction and opioid side effects. RESULTS: Pain scores on the NRS and SFMPQ were significantly lower and electronic pressure algometer measurements were significantly higher in the EA group than in the control group (p<0.001) at all assessments. In the EA group a significant decrease in rescue analgesia was observed at 45 min (p<0.001) and a significant decrease in cortisol levels was also observed (p<0.05). Patients expressed satisfaction with the analgesia, especially in the EA group (p<0.01). Significant delays in the start of bowel movements were observed in the control group at 45 min (p<0.001) and 2 h (p<0.05). CONCLUSIONS: Adding EA perioperatively should be considered an option as part of a multimodal analgesic strategy.  
  Address Department of Anaesthesiology, General Hospital of Thessaloniki “G. Gennimatas”, , Thessaloniki, Greece.  
  Publisher
  Language Number of Treatments 2  
  Treatment Follow-up N/A Frequency N/A Number of Participants 75  
  Time in Treatment 1 Day Condition Pain, Postoperative
  Disease Category Anesthesia and Analgesia OCSI Score  
  Notes Approved no  
  Call Number Serial 916  
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