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Author (up) Joos, S.; Schott, C.; Zou, H.; Daniel, V.; Martin, E. url  openurl
  Title Immunomodulatory effects of acupuncture in the treatment of allergic asthma: a randomized controlled study Type of Study RCT
  Year 2000 Publication The journal of alternative and complementary medicine : research on paradigm, practice, and policy Abbreviated Journal J Altern Complement Med  
  Volume 6 Issue 6 Pages 519-525  
  Keywords Acu Versus Sham; Acupuncture; AcuTrials; Asthma; Penetrating Sham; Lung Diseases; Non Specific Acupoint Control; RCT; Respiratory Tract Diseases; Restricted Modalities, Acupuncture Only; Semi-Individualized Acupuncture Protocol; Superficial Needling Depth; Sham Control; TCM Acupuncture Style; Traditional Diagnosis Based Point Selection; Allergies  
  Abstract OBJECTIVE: According to Traditional Chinese Medicine (TCM) acupuncture is a suitable treatment for complex chronic diseases such as bronchial asthma. In a randomized, controlled study we investigated immunologic effects of Chinese acupuncture on patients with allergic asthma. PATIENTS AND METHODS: The effects of acupuncture treatment given according to the principles of TCM (TCM group, n = 20) were compared with those of acupuncture treatment using points not specific for asthma (control group, n = 18). All patients were treated 12 times for 30 minutes over a time period of 4 weeks. Patients' general well-being and several peripheral blood parameters (eosinophils, lymphocyte subpopulations, cytokines, in vitro lymphocyte proliferation) were determined before and after acupuncture treatment. RESULTS: In the TCM group, significantly more patients indicated an improvement in general well-being (79% in the TCM group versus 47% in the control group; p = 0.049) after acupuncture treatment. The following changes were found in the TCM group: within the lymphocyte subpopulations the CD3+ cells (p = 0.005) and CD4+ cells (p = 0.014) increased significantly. There were also significant changes in cytokine concentrations: interleukin (IL)-6 (p = 0.026) and IL-10 (p = 0.001) decreased whereas IL-8 (p = 0.050) rose significantly. Additionally, the in vitro lymphocyte proliferation rate increased significantly (p = 0.035) while the number of eosinophils decreased from 4.4% to 3.3% after acupuncture (p > 0.05). The control group, however, showed no significant changes apart from an increase in the CD4+ cells (p = 0.012). CONCLUSION: The results imply that asthma patients benefit from acupuncture treatment given in addition to conventional therapy. Furthermore, acupuncture performed in accordance with the principles of TCM showed significant immune-modulating effects  
  Address Department of Anaesthetics, University of Heidelberg, Germany. s.joos@gmx.de  
  Publisher
  Language Number of Treatments 12  
  Treatment Follow-up 3 Days Frequency >1/WK Number of Participants 38  
  Time in Treatment 4 Weeks Condition Asthma
  Disease Category Respiratory Tract Diseases OCSI Score 72  
  Notes Approved no  
  Call Number Serial 539  
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