||Objective: to observe the curative effect of Tranquilizing Mind Acupuncture treatment for insomnia. Methods: 70 patients with insomnia were randomly divided into the treatment group and the control group. In the treatment group (n = 35), patients were assigned to Tranquilizing Mind acupuncture treatment while in the control group (n = 35), patients were administered with Estazolam. Results: according to the symptom scores, the total effective rate was 97.14 and 94.28% in the treatment and control groups, respectively; according to the Pittsburgh Sleep Quality Index (PSQI) deduction rate, the total effective rate of the treatment group and the control group was 94.28 and 91.42%, respectively; in comparison, the treatment group was more effective in improving sleep quality than the control group (P < 0.05). Conclusion: Tranquilizing Mind Acupuncture Treatment displayed satisfied curative effect for insomnia.