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Author Zhuang, L.; Yang, Z.; Zeng, X.; Zhua, X.; Chen, Z.; Liu, L.; Meng, Z. url  openurl
  Title The Preventive and Therapeutic Effect of Acupuncture for Radiation-Induced Xerostomia in Patients With Head and Neck Cancer: A Systematic Review Type of Study Systematic Review
  Year 2012 Publication Integrative cancer therapies Abbreviated Journal Integr Cancer Ther  
  Volume Issue Pages -  
  Keywords AcuTrials; Systematic Review; Neoplasms; Xerostomia; Acupuncture; Dry Mouth; Cancer  
  Abstract (up) Background. METHODS: Some studies suggest that acupuncture may be beneficial. Objectives. The authors evaluated the preventive and therapeutic effect of acupuncture for radiation-induced xerostomia among patients with head and neck cancer. Methods. PUBMED, EMBASE, Cochrane Library, CBM, CAJD, Wan Fang database, and VIP Database for Chinese Technical Periodicals were electronically searched, in conjunction with further manual search for relevant articles. Studies that met the inclusion criteria were systematically evaluated. RESULTS: Three randomized controlled trials (RCTs) investigating the therapeutic effect of acupuncture were included. One RCT on the preventive effect of acupuncture was found. Because of the considerable variation among included studies, meta-analysis was not possible. Two included RCTs used placebo controls, and both observed significant improvement in the salivary flow rates between acupuncture and control groups. However, no significant differences were found. Three included RCTs suggested that acupuncture for radiation-induced xerostomia can improve patients' subjective symptoms. The only study evaluating the preventive effect of acupuncture for radiation-induced xerostomia showed positive changes in salivary flow rates (both unstimulated and stimulated) and dry mouth -related symptoms. Acupuncture treatment was well tolerated by all patients and no severe adverse effects were seen. CONCLUSIONS: Insufficient evidence is available to judge whether acupuncture is safe and whether it is effective in preventing or treating radiation-induced xerostomia. Significant research remains to be done before acupuncture can be recommended for routine use in radiation-induced xerostomia.  
  Address Fudan University Shanghai Cancer Center, Shanghai, China; Shanghai Medical College, Fudan University, Shanghai, China.  
  Publisher
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition Xerostomia
  Disease Category Neoplasms OCSI Score  
  Notes Approved no  
  Call Number Serial 1495  
Permanent link to this record
 

 
Author Liu, B.; Chen, J.; Wang, J.; Liu, X.; Duan, X.; Shang, X.; Long, Y.; Chen, Z.; Li, X.; Huang, Y.; He, Y. openurl 
  Title Altered small-world efficiency of brain functional networks in acupuncture at ST36: a functional MRI study Type of Study RCT
  Year 2012 Publication Public Library of Science One Abbreviated Journal PLoS One  
  Volume 7 Issue 6 Pages e39342, 1-13  
  Keywords AcuTrials; Healthy Subjects; RCT; Acu Versus Sham; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Sham Control; Penetrating Sham; Mechanical; Near Verum Acupoint Control; fMRI; Functional MRI  
  Abstract (up) BACKGROUND: Acupuncture in humans can produce clinical effects via the central nervous system. However, the neural substrates of acupuncture's effects remain largely unknown. RESULTS: We utilized functional MRI to investigate the topological efficiency of brain functional networks in eighteen healthy young adults who were scanned before and after acupuncture at the ST36 acupoints (ACUP) and its sham point (SHAM). Whole-brain functional networks were constructed by thresholding temporal correlations matrices of ninety brain regions, followed by a graph theory-based analysis. We showed that brain functional networks exhibited small-world attributes (high local and global efficiency) regardless of the order of acupuncture and stimulus points, a finding compatible with previous studies of brain functional networks. Furthermore, the brain networks had increased local efficiency after ACUP stimulation but there were no significant differences after SHAM, indicating a specificity of acupuncture point in coordinating local information flow over the whole brain. Moreover, significant (P<0.05, corrected by false discovery rate approach) effects of only acupuncture point were detected on nodal degree of the left hippocampus (higher nodal degree at ACUP as compared to SHAM). Using an uncorrected P<0.05, point-related effects were also observed in the anterior cingulate cortex, frontal and occipital regions while stimulation-related effects in various brain regions of frontal, parietal and occipital cortex regions. In addition, we found that several limbic and subcortical brain regions exhibited point- and stimulation-related alterations in their regional homogeneity (P<0.05, uncorrected). CONCLUSIONS: Our results suggest that acupuncture modulates topological organization of whole-brain functional brain networks and the modulation has point specificity. These findings provide new insights into neuronal mechanism of acupuncture from the perspective of functional integration. Further studies would be interesting to apply network analysis approaches to study the effects of acupuncture treatments on brain disorders.  
  Address Department of Radiology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangdong, China. lbgdhtcm@163.com  
  Publisher
  Language Number of Treatments 2  
  Treatment Follow-up N/A Frequency 1/WK Number of Participants 18  
  Time in Treatment 2 Weeks Condition Healthy Subjects
  Disease Category Healthy Subjects OCSI Score  
  Notes Date of Input: 6/25/2015; Date Modified: 10/1/2015; Priority: Normal; Department of Radiology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangdong, China. lbgdhtcm@163.com; eng; Web: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=22761766 Approved yes  
  Call Number OCOM @ refbase @ Serial 1830  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2457  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2498  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2539  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2580  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2621  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2660  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2701  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2744  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2785  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2826  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2867  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2908  
Permanent link to this record
 

 
Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract (up) BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2949  
Permanent link to this record
 

 
Author Shen, Y.; Liu, L.; Chiang, J.S.; Meng, Z.; Garcia, M.K.; Chen, Z.; Peng, H.; Bei, W.; Zhao, Q.; Spelman, A.R.; Cohen, L. openurl 
  Title Randomized, placebo-controlled trial of K1 acupoint acustimulation to prevent cisplatin-induced or oxaliplatin-induced nausea Type of Study Journal Article
  Year 2015 Publication Cancer Abbreviated Journal  
  Volume 121 Issue 1 Pages 84-92  
  Keywords AcuTrials; Neoplasms; Chemotherapy Side Effects; Nausea; Cancer; Antineoplastic Agents; Liver Cancer; Acu + Usual Care Versus Sham + Usual Care; Transcutaneous Electrical Nerve Stimulation; Tens; TCM Acupuncture Style; Fixed Acupuncture Protocol; Sham Control; Non Penetrating Sham, Electrical; Sham Acupoint Control; Rct  
  Abstract (up) BACKGROUND: Greater than 70% of patients with cancer experience chemotherapy-induced nausea and vomiting. In the current study, the authors examined the effects of electrostimulation of the K1 acupoint located on the sole of the foot because it is believed to have the potential to control chemotherapy-induced nausea and vomiting. METHODS: In this trial, 103 patients diagnosed with primary or metastatic liver cancer were recruited before transcatheter arterial infusion (TAI) of cisplatin or oxaliplatin and randomized to either group A (51 patients who were treated with the antiemetic tropisetron and acustimulation at the K1 acupoint for 20 minutes approximately 1 to 2 hours before TAI on the first day and then daily for the subsequent 5 days) or group B (52 patients who were treated with tropisetron and electrostimulation at a placebo point on the heel). The rate, intensity, and duration of nausea and vomiting were collected at baseline and then daily for 5 days after TAI. Quality of life was assessed daily using the MD Anderson Symptom Inventory and the EuroQoL scale. RESULTS: No differences were found between groups A and B with regard to the incidence and degree of nausea or vomiting on day 1 or the following 5 days. Patients in group A had better EuroQoL scores compared with patients in group B (72.83 in group A vs 65.94 in group B; P =.04) on day 4 but not on the other days. No group differences were noted at any time point for MD Anderson Symptom Inventory scores. CONCLUSIONS: Electrostimulation of K1 combined with antiemetics did not result in initial prevention of cisplatin-induced or oxaliplatin-induced nausea or vomiting.  
  Address Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.  
  Publisher (c) 2014 American Cancer Society.
  Language Number of Treatments 6  
  Treatment Follow-up 5 Days Frequency >1/WK Number of Participants 103  
  Time in Treatment 1 Week Condition Chemotherapy side-effects
  Disease Category Neoplasms OCSI Score  
  Notes Date of Input: 4/7/2015; Date Modified: 5/7/2015; Availability: --In File--; Priority: Normal; Chemotherapy Side Effects; Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.; eng; Web: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=25204437 Approved no  
  Call Number OCOM @ refbase @ Serial 1690  
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Author Guo, T.; Chen, X.; Wu, X.; Shan, E.; Jin, Y.; Tai, X.; Liu, Z.; Zhu, B.; Yuan, K.; Chen, Z. url  doi
openurl 
  Title Acupuncture for osteoporosis: a systematic review protocol Type of Study
  Year 2016 Publication Systematic Reviews Abbreviated Journal Syst Rev  
  Volume 5 Issue 1 Pages 161  
  Keywords  
  Abstract (up) BACKGROUND: Osteoporosis is a global high prevalence of chronic metabolic disease with serious disability-adjusted life years losing. Acupuncture is used to treat osteoporosis broadly in China and other countries although the evidence on effectiveness cannot give a certain answer. The aim of this systematic review protocol is to appraise the efficacy and safety of acupuncture for osteoporosis. METHODS: A literature search of randomized controlled trials focusing on acupuncture for osteoporosis will be performed in the databases of Medline, Cochrane Library, Web of Science, EBASE, Springer, WHO International Clinical Trials Registry Platform (ICTRP), China National Knowledge Infrastructure (CNKI), Wan fang, Chinese Biomedical Literature Database (CBM), Chinese Scientific Journal Database (VIP), and other possible resources with a valid search strategy. Outcomes of pain, bone mineral density, fracture, mortality, improvement proportion, biochemical indicators, quality of life, adverse event, and other valid will be extracted and merged for quantitative analysis using Review Manager software (V.5.3.5) or descriptive analysis correspondingly. DISCUSSION: This is the first systematic review to estimate the effect of acupuncture on osteoporosis, and the result may provide evidence to clinical doctor. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016037829.  
  Address School of Acupuncture-Tuina and Rehabilitation, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan Province, China. 0871czk@sina.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:27653783; PMCID:PMC5031268 Approved no  
  Call Number OCOM @ refbase @ Serial 2152  
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Author Yin, X.; Xu, J.; Dong, B.; Ma, J.; Chen, Z.; Yin, P.; Wu, J.; Zhu, B.; Cao, Y.; Zheng, H.; Lao, L.; Xu, S. url  openurl
  Title Efficacy and Safety of Electroacupuncture on Treating Depression Related Sleep Disorders: Study Protocol of a Randomized Controlled Trial Type of Study Journal Article
  Year 2016 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evidence-based Complementary & Alternative Medicine (eCAM)  
  Volume Issue Pages 1-7  
  Keywords INSOMNIA -- Treatment; SLEEP disorders -- Treatment; MENTAL depression; Electroacupuncture; HAMILTON Depression Inventory; RESEARCH -- Methodology; PATIENTS -- Safety measures; SELF-report inventories; RANDOMIZED controlled trials  
  Abstract (up) Copyright of Evidence-based Complementary & Alternative Medicine (eCAM) is the property of Hindawi Publishing Corporation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)  
  Address  
  Publisher Hindawi Publishing Corporation
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 120459154; Source Information: 12/29/2016, p1; Subject Term: INSOMNIA -- Treatment; Subject Term: SLEEP disorders -- Treatment; Subject Term: MENTAL depression; Subject Term: ELECTROACUPUNCTURE; Subject Term: HAMILTON Depression Inventory; Subject Term: RESEARCH -- Methodology; Subject Term: PATIENTS -- Safety measures; Subject Term: SELF-report inventories; Subject Term: RANDOMIZED controlled trials; Subject Term: ; Number of Pages: 7p; ; Illustrations: 1 Diagram, 2 Charts; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2254  
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Author Lei, H.; Chen, X.; Liu, S.; Chen, Z. url  openurl
  Title Effect of Electroacupuncture on Visceral and Hepatic Fat in Women with Abdominal Obesity: A Randomized Controlled Study Based on Magnetic Resonance Imaging Type of Study Journal Article
  Year 2017 Publication Journal of Alternative & Complementary Medicine Abbreviated Journal Journal of Alternative & Complementary Medicine  
  Volume 23 Issue 4 Pages 285-294  
  Keywords OBESITY -- Treatment; FATTY liver -- Prevention; ACUPUNCTURE points; ADIPOSE tissues; ALTERNATIVE medicine; Anthropometry; HUMAN body composition; CLINICAL trials; Electroacupuncture; LONGITUDINAL method; MAGNETIC resonance imaging; Mathematics; PROBABILITY theory; RESEARCH -- Finance; SAMPLING (Statistics); Statistics; T-test (Statistics); WOMEN -- Health; DATA analysis; BODY mass index; RANDOMIZED controlled trials; PRE-tests & post-tests; DATA analysis -- Software; WAIST circumference; DESCRIPTIVE statistics; ABDOMINAL adipose tissue; MANN Whitney U Test; China  
  Abstract (up) Copyright of Journal of Alternative & Complementary Medicine is the property of Mary Ann Liebert, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)  
  Address  
  Publisher
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 122401275; Source Information: Apr2017, Vol. 23 Issue 4, p285; Subject Term: OBESITY -- Treatment; Subject Term: FATTY liver -- Prevention; Subject Term: ACUPUNCTURE points; Subject Term: ADIPOSE tissues; Subject Term: ALTERNATIVE medicine; Subject Term: ANTHROPOMETRY; Subject Term: HUMAN body composition; Subject Term: CLINICAL trials; Subject Term: ELECTROACUPUNCTURE; Subject Term: LONGITUDINAL method; Subject Term: MAGNETIC resonance imaging; Subject Term: MATHEMATICS; Subject Term: PROBABILITY theory; Subject Term: RESEARCH -- Finance; Subject Term: SAMPLING (Statistics); Subject Term: STATISTICS; Subject Term: T-test (Statistics); Subject Term: WOMEN -- Health; Subject Term: DATA analysis; Subject Term: BODY mass index; Subject Term: RANDOMIZED controlled trials; Subject Term: PRE-tests & post-tests; Subject Term: DATA analysis -- Software; Subject Term: WAIST circumference; Subject Term: DESCRIPTIVE statistics; Subject Term: ABDOMINAL adipose tissue; Subject Term: MANN Whitney U Test; Subject Term: ; Geographic Subject: CHINA; Geographic Subject: ; Number of Pages: 10p; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2251  
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Author Zhou, J.; Wu, Z.; Chen, Z.; Zhao, X.; Hu, J.; Jiao, Y.; Li, G.; Pang, Li url  doi
openurl 
  Title Clinical effect of acupuncture on endemic skeletal fluorosis: a randomized controlled trial Type of Study RCT
  Year 2013 Publication Evidence-based complementary and alternative medicine : eCAM Abbreviated Journal Evid Based Complement Alternat Med  
  Volume 2013 Issue Pages 1-5  
  Keywords AcuTrials; Stomatognathic Diseases; Fluorosis, Dental; Skeletal Fluorosis; RCT; Acu Versus Usual Care; Acupuncture; TCM Acupuncture Style; Semi-Individualized Acupuncture Protocol; Usual Care Control, Pharmaceutical; Traditional Diagnosis Based Point Selection; Symptom Based Point Selection; Restricted Modalities, Acupuncture Only; Electroacupuncture; Arthralgia  
  Abstract (up) Objective. To evaluate the effect of acupuncture on endemic skeletal fluorosis (ESF) through the randomized controlled trial. Methods. Ninety-nine cases were divided into the treatment group (68 cases) and the control group (31 cases) randomly. Normal acupuncture combined with electroacupuncture was used in treatment group, while Caltrate with vitamin D tablets were applied in control group. After 2 courses, the VAS, urinary fluoride, serum calcium, and serum phosphate were evaluated before and after treatment. Results. Both of these two methods could relieve pain effectively and the effect of acupuncture was better (P < 0.05). In treatment group, the content of urinary fluoride after treatment was higher than before (P < 0.05), while the content of serum calcium and phosphate was lower (P < 0.05). Conclusion. The effect of acupuncture on relieving pain and promoting discharge of urinary fluoride is better than that of western medicine. Acupuncture can reduce the content of serum calcium and phosphate.  
  Address Acupuncture and Moxibustion Institute of China Academy of Chinese Medical Science, Beijing 100700, China  
  Publisher
  Language Number of Treatments 24  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants 99  
  Time in Treatment 8 Weeks Condition Fluorosis, Dental
  Disease Category Stomatognathic Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 1481  
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