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Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2438  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2479  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2520  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2561  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2602  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2639  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2680  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2725  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2766  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2807  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2848  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2889  
Permanent link to this record
 

 
Author Oka, H.; Matsudaira, K.; Takano, Y.; Kasuya, D.; Niiya, M.; Tonosu, J.; Fukushima, M.; Oshima, Y.; Fujii, T.; Tanaka, S.; Inanami, H. url  doi
openurl 
  Title A comparative study of three conservative treatments in patients with lumbar spinal stenosis: lumbar spinal stenosis with acupuncture and physical therapy study (LAP study) Type of Study Journal Article
  Year 2018 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 18 Issue 1 Pages 19  
  Keywords (up) *Acupuncture Therapy; Aged; Conservative Treatment; Female; Humans; Lumbar Vertebrae/*physiopathology; Male; Patient Satisfaction; *Physical Therapy Modalities; Spinal Stenosis/*physiopathology/*therapy; Acupuncture; Conservative management; Exercise; Lumbar spinal stenosis; Medication; Zurich claudication questionnaire  
  Abstract BACKGROUND: Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparative trial of three types of conservative management (medication with acetaminophen, exercise, and acupuncture) in Japanese patients with LSS. METHODS: Patients with L5 root radiculopathy associated with LSS who visited our hospital for surgical treatment were enrolled between December 2011 and January 2014. In this open-label study, patients were assigned to three treatment groups (medication, exercise, acupuncture) according to the visit time. The primary outcomes were Zurich claudication questionnaire (ZCQ) scores before and after 4 weeks of treatment. Least square mean analysis was used to assess the following dependent variables in the treatment groups: changes in symptom severity and physical function scores of the ZCQ and the ZCQ score of patient's satisfaction after treatment. RESULTS: Thirty-eight, 40, and 41 patients were allocated to the medication, exercise, and acupuncture groups, respectively. No patient underwent surgical treatment during the study period. The symptom severity scores of the ZCQ improved significantly after treatment in the medication (p = 0.048), exercise (p = 0.003), and acupuncture (p = 0.04) groups. The physical function score improved significantly in the acupuncture group (p = 0.045) but not in the medication (p = 0.20) and exercise (p = 0.29) groups. The mean reduction in the ZCQ score for physical function was significantly greater for acupuncture than for exercise. The mean ZCQ score for treatment satisfaction was significantly greater for acupuncture than for medication. CONCLUSIONS: Acupuncture was significantly more effective than physical exercise according to the physical function score of the ZCQ and than medication according to the satisfaction score. The present study provides new important information that will aid decision making in LSS treatment. TRIAL REGISTRATION: This study was registered with the UMIN Clinical Trials Registry ( UMIN000006957 ).  
  Address Department of Orthopedic Surgery, Iwai Orthopaedic Medical Hospital, Tokyo, Japan  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29351748; PMCID:PMC5775532 Approved no  
  Call Number OCOM @ refbase @ Serial 2930  
Permanent link to this record
 

 
Author Elden, H.; Ostgaard, H. C.; Fagevik-Olsen, M.; Ladfors, L.; Hagberg, H. url  openurl
  Title Treatments of pelvic girdle pain in pregnant women: adverse effects of standard treatment, acupuncture and stabilising exercises on the pregnancy, mother, delivery and the fetus/ neonate Type of Study RCT
  Year 2008 Publication BMC complementary and alternative medicine [electronic resource] Abbreviated Journal BMC Complement Altern Med  
  Volume 8 Issue 1 Pages 34-  
  Keywords (up) Acu + Usual Care Versus > 1 Control; Adverse Effects; Analgesia; Delivery, Obstetric; Exercise; Pain; RCT; TCM Acupuncture Style; Women's Health; Usual Care Control, Multimodality; Semi-Individualized Acupuncture Protocol; Traditional Diagnosis Based Point Selection; Restricted Modalities, Acupuncture + Other; AcuTrials; CAM Control  
  Abstract ABSTRACT: BACKGROUND: Previous publications indicate that acupuncture is efficient for the treatment of pelvic girdle pain, PGP, in pregnant women. However, the use of acupuncture for PGP is rare due to insufficient documentation of adverse effects of this treatment in this specific condition. The aim of the present work was to assess adverse effects of acupuncture on the pregnancy, mother, delivery and the fetus/ neonate in comparison with women that received stabilising exercises as adjunct to standard treatment or standard treatment alone. METHODS: In all, 386 women with PGP entered this controlled, single-blind trial. They were randomly assigned to standard treatment plus acupuncture (n=125), standard treatment plus specific stabilising exercises (n=131) or to standard treatment alone (n=130) for 6 weeks. Acupuncture that may be considered strong was used and treatment was started as early as in the second trimester of pregnancy. Adverse effects were recorded during treatment and throughout the pregnancy. Influence on the fetus was measured with cardiotocography (CTG) before-during and after 43 acupuncture sessions in 43 women. A standardised computerized method to analyze the CTG reading numerically (Oxford 8000, Oxford, England) was used. After treatment, the women rated their overall experience of the treatment and listed adverse events if any in a questionnaire. Data of analgesia and oxytocin augmentation during labour, duration of labour, frequency of preterm birth, operative delivery, Apgar score, cord-blood gas/ acid base balance and birth weight were also recorded. RESULTS: There were no serious adverse events after any of the treatments. Minor adverse events were common in the acupuncture group but women rated acupuncture favourably even despite this. The computerized or visually assessed CTG analyses of antenatal recordings in connection with acupuncture were all normal. CONCLUSIONS: This study shows that acupuncture administered with a stimulation that may be considered strong led to minor adverse complaints from the mothers but had no observable severe adverse influences on the pregnancy, mother, delivery or the fetus/ neonate  
  Address  
  Publisher
  Language Number of Treatments 12  
  Treatment Follow-up 1 Week Frequency >1/WK Number of Participants 386  
  Time in Treatment 6 Weeks Condition Pelvic Girdle Pain
  Disease Category Adverse Effects OCSI Score  
  Notes Approved no  
  Call Number Serial 287  
Permanent link to this record
 

 
Author Shiue, H.-S.; Lee, Y.-S.; Tsai, C.-N.; Chang, H.-H. url  doi
openurl 
  Title Treatment of allergic rhinitis with acupoint herbal plaster: an oligonucleotide chip analysis Type of Study Journal Article
  Year 2016 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 16 Issue 1 Pages 436  
  Keywords (up) Acupoint herbal plaster; Allergic rhinitis; Oligonucleotide chip  
  Abstract BACKGROUND: Allergic rhinitis is regarded as an imbalanced Th1/Th2 cell-mediated response. The present study used microarray analysis to compare gene expression levels between allergic rhinitis patients before and after a series of acupoint herbal plaster applications. METHODS: In this experimental pilot study, volunteers experiencing sneezing, runny nose, and congestion for more than 9 months in the year following initial diagnoses were included after diagnostic confirmation by otolaryngologists to exclude patients with sinusitis and nasal polyps. Patients with persistent allergic rhinitis each received four acupoint herbal plaster treatments applied using the moxibustion technique. Clinical outcomes were evaluated using the Rhinitis Quality of Life Questionnaire (RQLQ). Peripheral blood samples were analyzed using an ImmunoCAP Phadiatop test, and patients were classified as phadiatop (Ph)-positive or -negative. Microarray results were analyzed for genes that were differentially expressed between (1) Ph-positive and -negative patients treated with herbal plaster; and (2) before and after herbal plaster treatment in the Ph-positive patient group. Unsupervised and supervised methods were used for gene-expression data analysis. RESULTS: Nineteen Ph-positive and four Ph-negative participants with persistent allergic rhinitis were included in the study. RQLQ results indicated that the 19 Ph-positive volunteers experienced improvement in six of seven categories following acupoint herbal plaster treatments, whereas the four Ph-negative participants reported improvement in only two categories. Hierarchical clustering and principle component analysis of the gene expression profiles of Ph-positive and -negative participants indicated the groups exhibited distinct physiological responses to acupoint herbal treatment. Evaluation of gene networks using MetaCore identified that the “Immune responseIL-13 signaling via JAK-STAT” and the “InflammationInterferon signaling” were down- and up-regulated, respectively, among Ph-positive subjects. CONCLUSIONS: In this preliminary study, we find that the IL-13 immune response via JAK-STAT signaling and interferon inflammation signaling were down- and upregulated, respectively, in the Ph-positive group. Further studies are required to verify these pathways in Ph-positive patients, and to determine the mechanism of such pathway dysregulation. TRIAL REGISTRATION: ClinicalTrials.gov: NCT02486159 . Registered 30 Jun 2015.  
  Address Departments of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan. tcmchh55@gmail.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:27814709; PMCID:PMC5097372 Approved no  
  Call Number OCOM @ refbase @ Serial 2116  
Permanent link to this record
 

 
Author Wang, S.; Yang, H.; Zhang, J.; Zhang, B.; Liu, T.; Gan, L.; Zheng, J. url  doi
openurl 
  Title Efficacy and safety assessment of acupuncture and nimodipine to treat mild cognitive impairment after cerebral infarction: a randomized controlled trial Type of Study Journal Article
  Year 2016 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 16 Issue Pages 361  
  Keywords (up) Acupuncture; Cerebral infarction; Mild cognitive impairment; Montreal Cognitive Assessment scale; Nimodipine  
  Abstract BACKGROUND: Cerebral infarction frequently leads to mild cognitive impairment (MCI). Prompt management of MCI can prevent vascular dementia and improve patient outcome. This single center randomized controlled trial aims to investigate the efficacy and safety of acupuncture and nimodipine to treat post-cerebral infarction MCI. METHODS: A total of 126 Chinese patients with post-cerebral infarction MCI recruited from the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine between April 2013 and June 2014 were randomized at 1:1: 1 ratio into nimodipine alone (30 mg/time and 3 times daily), acupuncture alone (30 min/time, 6 times/week), and nimodipine + acupuncture groups. The treatments were 3 months. Cognitive function was evaluated using Montreal Cognitive Assessment (MoCA) scale at enrollment interview, at the end of 3-month therapy, and at the post-treatment 3-month follow-up. RESULTS: The per-protocol set included 39, 40, and 40 patients from nimodipine alone, acupuncture alone, and the combination group, respectively, was analyzed. Intra-group comparison revealed that MoCA score at the follow-up improved significantly by 15.8 +/- 10.9, 20.9 +/- 13.8 %, and 30.2 +/- 19.7 % compared with the baseline MoCA for nimodipine alone, acupuncture alone, and the combination group, respectively. Inter-group comparison demonstrated that the combination therapy improved MoCA score (5.5 +/- 2.2) at significantly higher extent than nimodipine alone (3.1 +/- 1.8) and acupuncture alone (4.3 +/- 2.3) at the follow-up (All P < 0.05), and significantly higher proportion of patients in acupuncture alone group (80 %) and the combination therapy group (90 %) than in nimodipine alone group (56.4 %) showed >/=12 % MoCA score improvement compared with the baseline MoCA (All P < 0.05). No adverse event was reported during the study. CONCLUSION: Acupuncture may be used as an additional therapy to conventional pharmacological treatment to further improve the clinical outcomes of patients with post-cerebral infarction MCI. TRIAL REGISTRATION: The study was registered at the Chinese Clinical Trial Registry ( http://www.chictr.org.cn/ , Unique Identifier: ChiCTR-IOR-15007366 ). The date of registration is November 4, 2015.  
  Address Department of Acupuncture, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. jgzheng2008@163.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:27623621; PMCID:PMC5022140 Approved no  
  Call Number OCOM @ refbase @ Serial 2155  
Permanent link to this record
 

 
Author Qin, Z.; Zang, Z.; Wu, J.; Zhou, J.; Liu, Z. url  doi
openurl 
  Title Efficacy of acupuncture for chronic prostatitis/chronic pelvic pain syndromes: study protocol for a randomized, sham acupuncture-controlled trial Type of Study Journal Article
  Year 2016 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 16 Issue 1 Pages 440  
  Keywords (up) Acupuncture; Chronic prostatitis/chronic pelvic pain syndrome; Efficacy; Randomized controlled trial  
  Abstract BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) affects many adult men worldwide. The currently available therapies offer little or no proven benefit for CP/CPPS. We designed this study to assess the efficacy of acupuncture therapy for the treatment of CP/CPPS. METHODS: This study is designed as a randomized, sham acupuncture-controlled trial. We will compare patients with CP/CPPS in an acupuncture group and a sham acupuncture group. Sixty-eight patients will be randomly allocated to receive acupuncture or sham acupuncture. The treatments will consist of 30-min sessions, three times weekly, for 8 weeks. The primary outcome measure is change in the weekly mean National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) total score from baseline through the 8-week treatment period. Secondary measures include the NIH-CPSI subscale scores, the total International Prostate Symptom Score (IPSS), patients' response rate, and patient satisfaction after treatment. We will also assess changes in the NIH-CPSI total score from baseline at the 20th and 32nd week of follow-up. DISCUSSION: This is a randomized, sham-controlled trial of acupuncture treatment for CP/CPPS. The results of this trial will provide more evidence on whether acupuncture is efficacious for treating CP/CPPS. TRIAL REGISTRATION: Clinical Trials.gov NCT02588274.  
  Address Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China. liuzhishun@aliyun.com  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:27821109; PMCID:PMC5100285 Approved no  
  Call Number OCOM @ refbase @ Serial 2114  
Permanent link to this record
 

 
Author Kim, N.; Yang, B.; Lee, T.; Kwon, S. url  openurl
  Title An economic analysis of usual care and acupuncture collaborative treatment on chronic low back pain: a Markov model decision analysis Type of Study Systematic Review
  Year 2010 Publication BMC complementary and alternative medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 10 Issue Pages 74-  
  Keywords (up) Acupuncture; Systematic Review; Back Pain; Low Back Pain, Chronic; AcuTrials; Cost Effectiveness; Cost-Benefit Analysis  
  Abstract BACKGROUND: The collaborative treatment of acupuncture in addition to routine care as an approach for the management of low back pain (LBP) is receiving increasing recognition from both public and professional arenas. In 2010, the Ministry of Health, Welfare and Family Affairs (MOHW) of South Korea approved the practice of doctors and Oriental medical doctors (acupuncture qualified) working together in the same facility and offering collaborative treatment at the same time for the same disease. However, there is little more than anecdotal evidence on the health and economic implications of this current practice. Therefore, the objective of this study is to examine the effectiveness and costs of acupuncture in addition to routine care in the treatment of chronic LBP patients in South Korea. METHODS: The Markov model was developed to synthesise evidence on both costs and outcomes for patients with chronic LBP. We conducted the base case analysis, univariate and probabilistic sensitivity analyses, and also performed the value of information analysis for future researches. Model parameters were sourced from systematic review of both alternatives, simple bibliographic reviews of relevant articles published in English or Korean, and statistical analyses of the 2005 and 2007 Korean National Health and Nutrition Survey (KNHNS) data. The analyses were based on the societal perspective over a five year time horizon using a 5% discount rate. RESULTS: In the base case, collaborative treatment resulted in better outcomes, but at a relatively high cost. Overall, the incremental cost-effectiveness ratio of a collaborative practice was 3,421,394 KRW (Korean rate Won) per QALY (Quality adjusted life year) (2,895.80 USD per QALY). Univariate sensitivity analysis of indirect non-medical costs did not affect the preference order of the strategies. Probabilistic sensitivity analysis revealed that if the threshold was over 3,260,000 KRW per QALY (2,759.20 USD per QALY), the probability for cost-effectiveness of a collaborative practice would exceed 50%. At 20,000,000 KRW per QALY, which is recommended using per capita gross domestic product (GDP) as the threshold, the probability would be 72.3%. CONCLUSIONS: On the basis of our findings, acupuncture collaborative therapy for patients with chronic LBP may be cost-effective if the usual threshold is applied. Further empirical studies are required to overcome the limitations of uncertainties and improve the precision of the results.  
  Address Seoul National University, Graduate School of Public Health, Seoul, South Korea. drkim@wonkwang.ac.kr  
  Publisher
  Language Number of Treatments  
  Treatment Follow-up N/A Frequency N/A Number of Participants  
  Time in Treatment N/A Condition Low Back Pain
  Disease Category Back Pain OCSI Score  
  Notes Approved no  
  Call Number Serial 578  
Permanent link to this record
 

 
Author Yang, M.; Li, X.; Liu, S.; Li, Z.; Xue, M.; Gao, D.; Li, X.; Yang, S. url  doi
openurl 
  Title Meta-analysis of acupuncture for relieving non-organic dyspeptic symptoms suggestive of diabetic gastroparesis Type of Study Systematic Review
  Year 2013 Publication BMC complementary and alternative medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 13 Issue 311 Pages 1-12  
  Keywords (up) AcuTrials; Diabetes Mellitus; Gastroparesis; Acupuncture; Electroacupuncture; Systematic Review; Warming Needle  
  Abstract BACKGROUND: Acupuncture is widely used to treat diabetic patients with dyspeptic symptoms suggestive of gastroparesis in China. We conducted this systematic review of randomized controlled trials (RCTs) to evaluate the efficacy of acupuncture for diabetic gastroparesis (DGP). METHODS: We searched PubMed, EMbase, Cochrane Central Register of Controlled Trials (CENTRAL) and four Chinese databases including China National Knowledge Infrastructure (CNKI), VIP Database for Chinese Technical Periodicals, Chinese Biomedical Literature Database (CBM) and WanFang Data up to January 2013 without language restriction. Eligible RCTs were designed to examine the efficacy of acupuncture in improving dyspeptic symptoms and gastric emptying in DGP. Risk of bias, study design and outcomes were extracted from trials. Relative risk (RR) was calculated for dichotomous data. Mean difference (MD) and standardized mean difference (SMD) were selected for continuous data to pool the overall effect. RESULTS: We searched 744 studies, among which 14 RCTs were considered eligible. Overall, acupuncture treatment had a high response rate than controls (RR, 1.20 [95% confidence interval (CI), 1.12 to 1.29], P < 0.00001), and significantly improved dyspeptic symptoms compared with the control group. There was no difference in solid gastric emptying between acupuncture and control. Acupuncture improved single dyspeptic symptom such as nausea and vomiting, loss of appetite and stomach fullness. Most studies were in unclear and high risk of bias and with small sample size (median = 62). The majority of the RCTs reported positive effect of acupuncture in improving dyspeptic symptoms. CONCLUSIONS: The results suggested that acupuncture might be effective to improve dyspeptic symptoms in DGP, while a definite conclusion about whether acupuncture was effective for DGP could not be drawn due to the low quality of trials and possibility of publication bias. Further large-scale, high-quality randomized clinical trials are needed to validate this claim and translate this result to clinical practice.  
  Address Xiamen Diabetes Institute, Xiamen, China  
  Publisher
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition Gastroparesis
  Disease Category Diabetes Mellitus OCSI Score  
  Notes Approved no  
  Call Number Serial 1369  
Permanent link to this record
 

 
Author Ursini, T.; Tontodonati, M.; Manzoli, L.; Polilli, E.; Rebuzzi, C.; Congedo, G.; Di Profio, S.; Toro, P. M.; Consorte, A.; Placido, G.; Lagana, S.; D'Amario, C.; Granchelli, C.; Parruti, G.; Pippa, L. url  openurl
  Title Acupuncture for the treatment of severe acute pain in herpes zoster: results of a nested, open-label, randomized trial in the VZV Pain Study Type of Study RCT
  Year 2011 Publication BMC complementary and alternative medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 11 Issue 46 Pages 1-8  
  Keywords (up) AcuTrials; Pain; RCT; Nervous System Diseases; Herpes Zoster; Acu Versus Usual Care; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Usual Care Control, Pharmaceutical  
  Abstract BACKGROUND: Data on the potential efficacy of acupuncture (AC) in controlling intense or very intense pain in patients with Herpes Zoster (HZ) has not been so far adequately assessed in comparison with standard pharmacological treatment (ST) by a controlled trial design. METHODS: Within the VZV Pescara study, pain was assessed in HZ patients on a Visual Analogue Scale (VAS) and by the McGill Pain Questionnaire (MPQ) both at the beginning and at the end of treatment. Response rates, mean changes in pain intensity, differences in total pain burden with an area-under-the-curve (AUC) method over a 1-year follow-up and differences in the incidence of Post-Herpetic Neuralgia (PHN) were evaluated. RESULTS: One hundred and two patients were randomized to receive either AC (n = 52) or ST (n = 50) for 4 weeks. Groups were comparable regarding age, sex, pain intensity at presentation and missed antiviral prescription. Both interventions were largely effective. No significant differences were observed in response rates (81.6% vs 89.2%, p = 0.8), mean reduction of VAS (4.1 +/- 2.3 vs 4.9 +/- 1.9, p = 0.12) and MPQ scores (1.3 +/- 0.9 vs 1.3 +/- 0.9, p = 0.9), incidence of PHN after 3 months (48.4% vs 46.8%, p = 0.5), and mean AUC during follow-up (199 +/- 136 vs 173 +/- 141, p = 0.4). No serious treatment-related adverse event was observed in both groups. CONCLUSIONS: This controlled and randomized trial provides the first evidence of a potential role of AC for the treatment of acute herpetic pain. TRIAL REGISTRATION: ChiCTR-TRC-10001146.  
  Address Infectious Diseases Unit, Pescara General Hospital, Pescara, Italy. parruti@tin.it; CN – VZV Pain Study Group  
  Publisher
  Language Number of Treatments 8  
  Treatment Follow-up 52 Weeks Frequency >1/WK Number of Participants 102  
  Time in Treatment 4 Weeks Condition Pain
  Disease Category Pain OCSI Score  
  Notes Approved no  
  Call Number Serial 1190  
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