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Author Jo, J.; Lee, Y.J.; Lee, H. url  doi
openurl 
  Title Effectiveness of Acupuncture for Primary Ovarian Insufficiency: A Systematic Review and Meta-Analysis Type of Study Systematic Review
  Year 2015 Publication Evidence-Based Complementary and Alternative Medicine : ECAM Abbreviated Journal Evid Based Complement Alternat Med  
  Volume 2015 Issue Pages 842180  
  Keywords AcuTrials; Systematic Review; Climacteric; Menopause; Acupuncture; Women's Health; Gynecology; Genital Diseases, Female; POI; Primary Ovarian Insufficiency  
  Abstract Objective. This systematic review aimed to assess current evidence from randomized controlled trials (RCTs) on the effects of acupuncture for patients with primary ovarian insufficiency (POI). Methods. We searched twelve databases to identify relevant studies published before July 2014. The outcomes were serum follicle-stimulating hormone (FSH) levels and resumption of menstruation. Two reviewers independently assessed the risk of bias using the Cochrane's tool, extracted the results, and evaluated the overall level of the evidence using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. Results. Eight RCTs were selected. Acupuncture significantly lowered serum FSH levels and more women receiving acupuncture reported resumption of menses. However, the results should be interpreted with caution due to a small number of participants, high risk of bias for blinding, and likely publication bias. The level of evidence for FSH level and resumption of menses were assessed as “low” using GRADE. Conclusion. The current evidence on acupuncture for POI is insufficient to draw a firm conclusion due to scarcity of studies with a low risk of bias and likely publication bias. Further rigorously designed and conducted studies are needed to confirm the effectiveness and safety of acupuncture in patients with POI.  
  Address (up) Acupuncture and Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition Primary Ovarian Insufficiency
  Disease Category Genital Diseases, Female OCSI Score  
  Notes PMID:26089949; PMCID:PMC4451156 Approved yes  
  Call Number OCOM @ refbase @ Serial 1959  
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