toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
   print

Deprecated: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in /home/acutrialsocom/public_html/refbase-ocom/includes/include.inc.php on line 5275
  Records Links
Author So, E. W.; Ng, E. H.; Wong, Y. Y.; Lau, E. Y.; Yeung, W. S.; Ho, P. C. url  openurl
  Title A randomized double blind comparison of real and placebo acupuncture in IVF treatment Type of Study RCT
  Year 2008 Publication Abbreviated Journal Hum Reprod  
  Volume Issue Pages -  
  Keywords Acu Versus Sham; Acupuncture; AcuTrials; Anxiety; Embryo Transfer; Fixed Acupuncture Protocol; Infertility, Female; IVF; Non Penetrating Sham, Mechanical; RCT; Restricted Modalities, Acupuncture Only; Sham Control; TCM Acupuncture Style; Verum Acupoint Control; Women's Health; Reproductive Techniques, Assisted; In Vitro Fertilization; Fertilization In Vitro  
  Abstract BACKGROUND Acupuncture has been used during IVF treatment as it may improve outcome, however, there are concerns about the true efficacy of this approach. This randomized double blind study aimed to compare real acupuncture with placebo acupuncture in patients undergoing IVF treatment. METHODS On the day of embryo transfer (ET), 370 patients were randomly allocated to either real or placebo acupuncture according to a computer-generated randomization list in sealed opaque envelopes. They received 25 min of real or placebo acupuncture before and after ET. The endometrial and subendometrial vascularity, serum cortisol concentration and the anxiety level were evaluated before and after real and placebo acupuncture. RESULTS The overall pregnancy rate was significantly higher in the placebo acupuncture group than that in the real acupuncture group (55.1 versus 43.8%, respectively, P = 0.038; Common odds ratio 1.578 95% confidence interval 1.047-2.378). No significant differences were found in rates of ongoing pregnancy and live birth between the two groups. Reduction of endometrial and subendometrial vascularity, serum cortisol concentration and the anxiety level were observed following both real and placebo acupuncture, although there were no significant differences in the changes in all these indices between the two groups. CONCLUSIONS Placebo acupuncture was associated with a significantly higher overall pregnancy rate when compared with real acupuncture. Placebo acupuncture may not be inert. Trial registered with HKClinicalTrials.com: number HKCTR-236  
  Address Department of Obstetrics and Gynaecology, The University of Hong Kong, Hong Kong Special Administrative Region, Pokfulam Road, Hong Kong, People's Republic of China  
  Publisher
  Language Number of Treatments 2  
  Treatment Follow-up N/A Frequency N/A Number of Participants (down) 370  
  Time in Treatment 1 Day Condition Fertilization In Vitro
  Disease Category Reproductive Techniques, Assisted OCSI Score  
  Notes Approved no  
  Call Number Serial 1083  
Permanent link to this record
 

 
Author Smith, C. A.; Crowther, C. A.; Collins, C. T.; Coyle, M. E. url  openurl
  Title Acupuncture to Induce Labor: A Randomized Controlled Trial Type of Study RCT
  Year 2008 Publication Obstetrics and gynecology Abbreviated Journal Obstet Gynecol  
  Volume 112 Issue 5 Pages 1067-1074  
  Keywords Acu Versus Sham; Acupuncture; AcuTrials; Fixed Acupuncture Protocol; Labor, Induced; Penetrating Sham; Near Verum Acupoint Control; RCT; Restricted Modalities, Acupuncture Only; Sham Control; Standard Needling Depth; TCM Acupuncture Style; Women's Health; Obstetric Surgical Procedures  
  Abstract OBJECTIVE: To estimate the clinical effectiveness of acupuncture to induce labor. METHODS: This study was a randomized controlled trial of acupuncture compared with sham acupuncture. Women who were scheduled for a postterm induction with a singleton pregnancy and cephalic presentation were eligible for the study. Women received two acupuncture or sham acupuncture sessions over a 2-day period before the planned medical/pharmacological induction. The principal primary outcomes related to the need for induction methods and time from the administration of the intervention to delivery. RESULTS: Three hundred sixty-four women were randomly assigned to the trial (treatment n=181 and control n=183). Women did not differ in their need for induction methods between groups: prostaglandin induction: relative risk (RR) 1.20, 95% confidence interval (CI) 0.96-1.51, P=.11; artificial rupture of membranes only: RR 0.93, 95% CI 0.72-1.20, P=.57; oxytocin only: RR 0.89, 95% CI 0.60-1.32, P=.55; artificial rupture of membranes plus oxytocin: RR 0.87, 95% CI 0.57-1.33, P=.52; prostaglandins, artificial rupture of membranes, and oxytocin: RR 0.84, 95% CI 0.37-1.91, P=.68. The median time from acupuncture to delivery was 68.6 hours (interquartile range 53.9-79.5) compared with 65 hours (interquartile range 49.3-76.3) for women in the control group. CONCLUSION: Two sessions of manual acupuncture, using local and distal acupuncture points, administered 2 days before a scheduled induction of labor did not reduce the need for induction methods or the duration of labor for women with a postterm pregnancy. CLINICAL TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry, www.anzctr.org.au, ACTRN12606000494538 LEVEL OF EVIDENCE: I  
  Address School of Paediatrics and Reproductive Health, the Department of Maternal Fetal Medicine, Discipline of Obstetrics and Gynaecology, and the Faculty of Health Sciences, Women's and Children's Health Research Institute, the University of Adelaide, Adel  
  Publisher
  Language Number of Treatments 2  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants (down) 364  
  Time in Treatment 1 Week Condition Labor, Induced
  Disease Category Obstetric Surgical Procedures OCSI Score  
  Notes Approved no  
  Call Number Serial 1065  
Permanent link to this record
 

 
Author Long, W. j.; Zhang, Q. m.; Wang, S. M. openurl 
  Title Ear acupuncture of epidemic parotitis: analysis of 362 cases Type of Study RCT
  Year 2000 Publication International Journal of Clinical Acupuncture Abbreviated Journal Int J Clin Acupunct  
  Volume 11 Issue 4 Pages 335-338  
  Keywords CAM Control; Acu Versus CAM Control; AcuTrials; Auricular Acupuncture; Herbal Formula; Herbal Formula; Parotitis; RCT; Restricted Modalities, Acupuncture Only; Semi-Individualized Acupuncture Protocol; TCM Acupuncture Style; Traditional Diagnosis Based Point Selection; Stomatognathic Diseases  
  Abstract  
  Address  
  Publisher
  Language Number of Treatments  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants (down) 362  
  Time in Treatment N/A Condition Parotitis
  Disease Category Stomatognathic Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 769  
Permanent link to this record
 

 
Author Lin, Q.; Li, X.; Han, J.; Leng, J. url  openurl
  Title Electro-acupuncture treatment for the upper segment ureterolithiasis under B-ultrasonography Type of Study RCT
  Year 2005 Publication Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine Abbreviated Journal J Tradit Chin Med  
  Volume 25 Issue 1 Pages 13-15  
  Keywords CAM Control; Acu Versus > 1 Control; Acupuncture; AcuTrials; Electroacupuncture; Herbal Formula; Herbal Formula; RCT; Restricted Modalities, Acupuncture + Other; Individualized Acupuncture Protocol; Usual Care Control, Pharmaceutical; Symptom Based Point Selection; TCM Acupuncture Style; Ureterolithiasis; Urinary Calculi; Urinary Stones; Urologic Diseases; Restricted Modalities, Acupuncture Only; Acu Versus Acu  
  Abstract In order to explore the effects of the local strong stimulation generated by electro-acupuncture for treatment of the upper segment ureterolithiasis, a controlled study was carried out among the treatment group (electro-acupuncture with strong stimulation), the control group I (medication) and the control group II (conventional acupuncture). The results showed that the differences in the cure rate and the total effective rate between the treatment group and the two control groups were significant in statistical analysis (P<0.05 and P<0.01 respectively). This indicates that better therapeutic effects can be obtained by the local strong stimulation generated by electro-acupuncture for treatment of the upper segment ureterolithiasis  
  Address TCM Department of the Rizhao Municipal People's Hospital, Rizhao Shandong 276800, China  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up N/A Frequency N/A Number of Participants (down) 360  
  Time in Treatment 1 Condition Ureterolithiasis
  Disease Category Urologic Diseases OCSI Score 46  
  Notes Approved no  
  Call Number Serial 719  
Permanent link to this record
 

 
Author Reinhold, T.; Brinkhaus, B.; Willich, S. N.; Witt, C. url  doi
openurl 
  Title Acupuncture in Patients Suffering from Allergic Asthma: Is It Worth Additional Costs? Type of Study
  Year 2013 Publication Journal of alternative and complementary medicine (New York, N.Y.) Abbreviated Journal J Altern Complement Med  
  Volume 20 Issue 3 Pages 169-177  
  Keywords AcuTrials; RCT; Respiratory Tract Diseases; Asthma; Acu Versus Wait List; Acupuncture; Unspecified Acupuncture Style; Individualized Acupuncture Protocol; Symptom Based Point Selection; Restricted Modalities, Acupuncture Only; Wait List Control; Cost Effectiveness  
  Abstract Objectives: Acupuncture is increasingly used in patients with allergic asthma, but there is a lack of evidence on the cost-benefit relationship of this treatment. The aim of this study was to assess economic aspects of additional acupuncture treatment in patients with allergic bronchial asthma compared to patients receiving routine care alone. Design, subjects, intervention, outcome measures: In a randomized controlled trial, patients with allergic bronchial asthma were either allocated to a group receiving acupuncture immediately or a waiting-list control group. Both groups were free to use routine care treatment. The resource consumption, costs, and health-related quality of life were evaluated at baseline, and after 3 and 6 months by using statutory health insurance information and standardized questionnaires. Main economic outcome parameters were direct and indirect cost differences during the study period and the incremental cost-effectiveness ratio (ICER) of acupuncture treatment. Results: Three hundred and six (306) patients (159 acupuncture; 147 controls) were included (mean age 46.5+/-13.11 years, female 57.2%) and were comparable at baseline. Acupuncture treatment was associated with significantly higher costs compared to control patients (overall costs: euro860.76 [95% confidence interval (CI) 705.04-1016.47] versus euro518.80 [95% CI 356.66-680.93]; p=0.003; asthma-related costs: euro517.52 [95% CI 485.63-549.40] versus euro144.87 [95% CI 111.70-178.05]; p<0.001). These additional costs seem essentially driven by acupuncture costs themselves (euro378.40 [95% CI 367.10-389.69]). However, acupuncture was associated with superior effectiveness in terms of quality-adjusted life years (QALYs). Resulting ICER lay between euro23,231 (overall) and euro25,315 (diagnosis-specific) per additional QALY. When using German acupuncture prices of year 2012, the ICER would improve to euro12.810 (overall) versus euro14,911 (diagnosis-specific) per QALY gained. Conclusions: Treating patients who have allergic bronchial asthma with acupuncture in addition to routine care resulted in additional costs and better effects in terms of patients' quality of life. Acupuncture therefore seems to be a useful and cost-effective add-on treatment.  
  Address Institute for Social Medicine, Epidemiology and Health Economics, Charite-University Medical Center, Berlin, Germany .  
  Publisher
  Language Number of Treatments 12  
  Treatment Follow-up 12 Weeks Frequency 1/WK Number of Participants (down) 357  
  Time in Treatment 12 Weeks Condition Asthma
  Disease Category Respiratory Tract Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 981  
Permanent link to this record
 

 
Author Foster, N. E.; Thomas, E.; Barlas, P.; Hill, J. C.; Young, J.; Mason, E.; Hay, E. M. url  openurl
  Title Acupuncture as an adjunct to exercise based physiotherapy for osteoarthritis of the knee: randomised controlled trial Type of Study RCT
  Year 2007 Publication BMJ : British medical journal / British Medical Association Abbreviated Journal BMJ  
  Volume 335 Issue 7617 Pages 436-  
  Keywords Acu Versus > 1 Control; Acupuncture; AcuTrials; Arthritis; Exercise; Non Penetrating Sham, Mechanical; Osteoarthritis, Knee; Pain; Physical Therapy; RCT; Restricted Modalities, Acupuncture Only; Semi-Individualized Acupuncture Protocol; Sham Control; Symptom Based Point Selection; TCM Acupuncture Style; Verum Acupoint Control  
  Abstract OBJECTIVE: To investigate the benefit of adding acupuncture to a course of advice and exercise delivered by physiotherapists for pain reduction in patients with osteoarthritis of the knee. DESIGN: Multicentre, randomised controlled trial. SETTING: 37 physiotherapy centres accepting primary care patients referred from general practitioners in the Midlands, United Kingdom. PARTICIPANTS: 352 adults aged 50 or more with a clinical diagnosis of knee osteoarthritis. INTERVENTIONS: Advice and exercise (n=116), advice and exercise plus true acupuncture (n=117), and advice and exercise plus non-penetrating acupuncture (n=119). MAIN OUTCOME MEASURES: The primary outcome was change in scores on the Western Ontario and McMaster Universities osteoarthritis index pain subscale at six months. Secondary outcomes included function, pain intensity, and unpleasantness of pain at two weeks, six weeks, six months, and 12 months. RESULTS: Follow-up rate at six months was 94%. The mean (SD) baseline pain score was 9.2 (3.8). At six months mean reductions in pain were 2.28 (3.8) for advice and exercise, 2.32 (3.6) for advice and exercise plus true acupuncture, and 2.53 (4.2) for advice and exercise plus non-penetrating acupuncture. Mean differences in change scores between advice and exercise alone and each acupuncture group were 0.08 (95% confidence interval -1.0 to 0.9) for advice and exercise plus true acupuncture and 0.25 (-0.8 to 1.3) for advice and exercise plus non-penetrating acupuncture. Similar non-significant differences were seen at other follow-up points. Compared with advice and exercise alone there were small, statistically significant improvements in pain intensity and unpleasantness at two and six weeks for true acupuncture and at all follow-up points for non-penetrating acupuncture. CONCLUSION: The addition of acupuncture to a course of advice and exercise for osteoarthritis of the knee delivered by physiotherapists provided no additional improvement in pain scores. Small benefits in pain intensity and unpleasantness were observed in both acupuncture groups, making it unlikely that this was due to acupuncture needling effects. TRIAL REGISTRATION: Current Controlled Trials ISRCTN88597683 [controlled-trials.com]  
  Address Primary Care Musculoskeletal Research Centre, Keele University, Stafford ST5 5BG. n.foster@keele.ac.uk  
  Publisher
  Language Number of Treatments 6  
  Treatment Follow-up 52 Weeks Frequency >1/WK Number of Participants (down) 352  
  Time in Treatment 3 Weeks Condition Osteoarthritis, Knee
  Disease Category Arthritis OCSI Score  
  Notes Approved no  
  Call Number Serial 333  
Permanent link to this record
 

 
Author Foster, N. E.; Thomas, E.; Hill, J. C.; Hay, E. M. url  openurl
  Title The relationship between patient and practitioner expectations and preferences and clinical outcomes in a trial of exercise and acupuncture for knee osteoarthritis Type of Study RCT
  Year 2009 Publication European journal of pain : EJP Abbreviated Journal Eur J Pain  
  Volume Issue Pages -  
  Keywords Acu Versus > 1 Control; Acupuncture; Miscellaneous; Non Penetrating Sham, Mechanical; Osteoarthritis, Knee; Patient-Practitioner Relationship; RCT; Sham Control; Usual Care Control, Educational; Usual Care Control, Physical; Verum Acupoint Control; AcuTrials; Arthritis  
  Abstract We investigated the relationship between patient and therapist preferences and expectations and clinical outcomes in a trial of exercise and acupuncture for clinical knee osteoarthritis. 352 Patients were randomised to advice and exercise or advice and exercise plus true or non-penetrating acupuncture. Before randomisation, patients recorded their general outcome expectations, treatment-specific preferences and expectations. Clinical outcome was (a) change scores on the Western Ontario and McMaster Osteoarthritis Index (WOMAC) and (b) treatment response according to the OMERACT-OARSI criteria. Physiotherapists recorded their treatment expectations and preferences for each patient following an assessment prior to randomisation. We investigated the relationship between (a) patient, (b) therapist and (c) matched patient-therapist preferences and expectations on clinical outcomes using univariate and multivariate analyses. There was no significant relationship between patients' treatment preferences and clinical outcomes at 6 or 12months nor between patients' expectations and pain (WOMAC) at 6 or 12months. Using our secondary outcome (OMERART-OARSI), those who received the treatment for which they had high expectations of benefit were almost twice as likely to be classified as a treatment responder at 6months (odds ratio (OR) 1.7 (95% Confidence Interval 1.06, 2.79)) and 12months (OR) 1.9 (1.13, 3.13). Therapists' preferences and expectations for individual patients did not add further explanation of outcomes. There was no evidence of a relationship between patients' treatment preferences or expectations and pain reduction. We found weak evidence, from secondary outcomes, that patients' expectations, both general and treatment-specific, are related to clinical outcome from exercise and acupuncture  
  Address Arthritis Research Campaign National Primary Care Centre, Primary Care Sciences, Keele University, Keele, Staffordshire ST5 5BG, United Kingdom  
  Publisher
  Language Number of Treatments  
  Treatment Follow-up 52 Weeks Frequency N/A Number of Participants (down) 352  
  Time in Treatment N/A Condition Osteoarthritis, Knee
  Disease Category Arthritis OCSI Score  
  Notes Approved no  
  Call Number Serial 334  
Permanent link to this record
 

 
Author Whitehurst, D. G.; Bryan, S.; Hay, E. M.; Thomas, E.; Young, J.; Foster, N. E. url  openurl
  Title Cost-Effectiveness of Acupuncture Care as an Adjunct to Exercise-Based Physical Therapy for Osteoarthritis of the Knee Type of Study RCT
  Year 2011 Publication Physical therapy Abbreviated Journal Phys Ther  
  Volume Issue Pages -  
  Keywords AcuTrials; Arthritis; Osteoarthritis, Knee; RCT; Acu + Usual Care Versus > 1 Control; Acupuncture; TCM Acupuncture Style; Semi-Individualized Acupuncture Protocol; Sham Control; Non Penetrating Sham, Mechanical; Verum Acupoint Control; Knee Pain; Usual Care Control, Multimodality; Restricted Modalities, Acupuncture Only; Symptom Based Point Selection  
  Abstract Background The delivery of acupuncture alongside mainstream interventions and the cost-effectiveness of “alternative” treatments remain areas of controversy. Objective The aim of this study was to assess the cost-utility of adding acupuncture to a course of advice and exercise delivered by UK National Health Service (NHS) physical therapists to people with osteoarthritis of the knee. Design A cost-utility analysis was performed alongside a randomized controlled trial. METHODS: A total of 352 adults (aged 50 years or older) were randomly assigned to receive 1 of 3 interventions. The primary analysis focused on participants receiving advice and exercise (AE) or advice and exercise plus true acupuncture (AE+TA). A secondary analysis considered participants receiving advice and exercise plus nonpenetrating acupuncture (AE+NPA). The main outcome measures were quality-adjusted life years (QALYs), measured by the EQ-5D, and UK NHS costs. RESULTS: were expressed as the incremental cost per QALY gained over 12 months. Sensitivity analyses included a broader cost perspective to incorporate private out-of-pocket costs. Results NHS costs were higher for AE+TA ( pound314 [British pounds sterling]) than for AE alone ( pound229), and the difference in mean QALYs favored AE+TA (mean difference=0.022). The base-case cost per QALY gained was pound3,889; this value was associated with a 77% probability that AE+TA would be more cost-effective than AE at a threshold of pound20,000 per QALY. Cost-utility data for AE+NPA provided cost-effectiveness estimates similar to those for AE+TA. Limitations As with all trial-based economic evaluations, caution should be exercised when generalizing results beyond the study perspectives. CONCLUSIONS:/b&gt; A package of AE+TA delivered by NHS physical therapists provided a cost-effective use of health care resources despite an associated increase in costs. However, the economic benefits could not be attributed to the penetrating nature of conventional acupuncture; therefore, further research regarding the mechanisms of acupuncture is needed. An analysis of alternative cost perspectives suggested that the results are generalizable to other health care settings.  
  Address Centre for Clinical Epidemiology and Evaluation (C2E2), Vancouver Coastal Health Research Institute, 7th Floor, 828 West 10th Ave, Vancouver, British Columbia, V5Z 1M9 Canada. Dr Whitehurst also is Honorary Research Fellow, Arthritis Research UK Prim  
  Publisher
  Language Number of Treatments 6  
  Treatment Follow-up 48 Weeks Frequency 1/WK Number of Participants (down) 352  
  Time in Treatment 6 Weeks Condition Osteoarthritis, Knee
  Disease Category Arthritis OCSI Score  
  Notes Approved no  
  Call Number Serial 1304  
Permanent link to this record
 

 
Author Ma, W.; Bai, W.; Lin, C.; Zhou, P.; Xia, L.; Zhao, C.; Hao, Y.; Ma, H.; Liu, X.; Wang, J.; Yuan, H.; Xie, Y.; Lu, A. url  openurl
  Title Effects of Sanyinjiao (SP6) with electroacupuncture on labour pain in women during labour Type of Study RCT
  Year 2011 Publication Complementary therapies in medicine Abbreviated Journal Complement Ther Med  
  Volume 1/1/1970 Issue Pages S13-8  
  Keywords AcuTrials; Labor, Obstetric; Analgesia; RCT; Acu Versus > 1 Control; Electroacupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Sham Control; Non Penetrating Sham, Electrical; Verum Acupoint Control; No Treatment Control; Labor Pain; Women's Health  
  Abstract OBJECTIVE: To evaluate the effects of Sanyinjiao (SP6) with electroacupuncture on labour pain in women during the labour process. METHODS: A total of 350 women in labour from three centres were randomly divided into the electroacupuncture group (acupuncture group), the sham electroacupuncture group (sham group) and the control group. Women in labour in the electroacupuncture group received the electroacupuncture on the point Sanyinjiao (SP6). The analgesic effect was self-rated by women in labour, using visual analogue scale (VAS). The duration and paralysis time of uterine contraction, uterine contraction regularity, degree of cervical extension, presentation of foetal descent, the condition of intra-partum haemorrhage and postpartum haemorrhage, labour manner, lochia, involution of uterus, milk secretion, neonate Apgar Score and neonate body height and weight were also measured. All data were analysed with Statistical Package for Social Sciences (SPSS) 12.0. RESULTS: Labour pain scores from women in the acupuncture group were less than in the control group at needle retaining at 30min, 2 and 4h after needle withdrawal. Other evaluated indices did not show significant differences among the three groups. No adverse events were observed during the labour process. CONCLUSION: SP6 with electroacupuncture could be an effective way for decreasing labour pain.  
  Address Beijing University of Chinese Medical Sciences, Beijing 100029, China. mawenzhu@163bj.com  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up N/A Frequency N/A Number of Participants (down) 350  
  Time in Treatment 1 Day Condition Analgesia
  Disease Category Labor, Obstetric OCSI Score  
  Notes Approved no  
  Call Number Serial 792  
Permanent link to this record
 

 
Author Wang, C.; Wu, Z.; Li, N.; Zhao, Y.; Tian, F.; Zhou, X.; Wang, Z. doi  openurl
  Title Clinical curative effect of electric acupuncture on acute cerebral infarction: a randomized controlled multicenter trial Type of Study RCT
  Year 2014 Publication J Tradit Chin Med Abbreviated Journal  
  Volume 34 Issue 6 Pages 635-640  
  Keywords RCT; Stroke; Acu + Usual Care Versus Usual Care; Electroacupuncture; TCM Acupuncture Style; Usual Care Control; Nervous System Diseases  
  Abstract OBJECTIVE: To examine whether electric acupuncture can improve the daily life of patients with ischemic cerebral apoplexy at acute stage. METHODS: A stratified-block randomized controlled multicenter trial was designed for this study. Totally 340 patients with acute ischemic cerebral apoplexy were randomly divided into an electric acupuncture group and a control group. In the electric acupuncture group, 170 patients were treated with electric acupuncture and routine therapy, and 170 patients in the control group with routine therapy alone. Major indexes for judging curative effect were Barthel index at 3- and 6- months follow-up visits and number of re-hospitalized patients. Minor indexes for judging curative effect were change in the score for nervous dysfunction at 4 and 12 weeks follow-up visits and number of patients persisting in rehabilitation treatment with acupuncture during follow-up visit. RESULTS: Baseline data at the time of case selection between the two groups were similar. The odds ratio (OR) was 0.92, and the 95% confidence interval (CI) was 0.49-1.73 in disabled rate and 0.73 and 0.51-1.05 in the number of re-hospitalized patients in the electric acupuncture group at 6-month follow up visit compared with the control group. There was no difference in the score for nervous dysfunction at the end of 12-week follow-up visit between the two groups. The score for nervous dysfunction at the end of 4-week treatment in the electric acupuncture group was significantly higher than that in the control group (P < 0.05). The number of patients discharged from hospital who persisted in rehabilitation treatment with acupuncture in the acupuncture group was significantly higher than that in the control group. CONCLUSION: Using electric acupuncture to treat patients with acute ischemic cerebral apoplexy can effectively improve the nervous dysfunction scores after 4-week treatment and their ability to deal with daily life after 6-month follow-up visit. Systematic treatment with acupuncture may also reduce the number of patients with secondary apoplexy.  
  Address  
  Publisher
  Language Number of Treatments  
  Treatment Follow-up 24 Frequency Number of Participants (down) 340  
  Time in Treatment Condition Stroke
  Disease Category Stroke OCSI Score  
  Notes Date of Input: 4/7/2015; Date Modified: 6/9/2015; Availability: --In File--; Priority: Normal; Stroke; eng; Web: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=25618965 Approved no  
  Call Number OCOM @ refbase @ Serial 1707  
Permanent link to this record
 

 
Author Xu, S. B.; Huang, B.; Zhang, C. Y.; Du, P.; Yuan, Q.; Bi, G. J.; Zhang, G. B.; Xie, M. J.; Luo, X.; Huang, G. Y.; Wang, W. url  doi
openurl 
  Title Effectiveness of strengthened stimulation during acupuncture for the treatment of Bell palsy: a randomized controlled trial Type of Study RCT
  Year 2013 Publication CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne Abbreviated Journal CMAJ  
  Volume 185 Issue 6 Pages 473-479  
  Keywords AcuTrials; Cranial Nerve Diseases; Bell Palsy; RCT; Acu Versus Acu; CAM Control; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only  
  Abstract BACKGROUND: The traditional Chinese theory of acupuncture emphasizes that the intensity of acupuncture must reach a threshold to generate de qi, which is necessary to achieve the best therapeutic effect. De qi is an internal compound sensation of soreness, tingling, fullness, aching, cool, warmth and heaviness, and a radiating sensation at and around the acupoints. However, the notion that de qi must be achieved for maximum benefit has not been confirmed by modern scientific evidence. METHODS: We performed a prospective multicentre randomized controlled trial involving patients with Bell palsy. Patients were randomly assigned to the de qi (n = 167) or control (n = 171) group. Both groups received acupuncture: in the de qi group, the needles were manipulated manually until de qi was reached, whereas in the control group, the needles were inserted without any manipulation. All patients received prednisone as a basic treatment. The primary outcome was facial nerve function at month 6. We also assessed disability and quality of life 6 months after randomization. RESULTS: After 6 months, patients in the de qi group had better facial function (adjusted odds ratio [OR] 4.16, 95% confidence interval [CI] 2.23-7.78), better disability assessment (differences of least squares means 9.80, 95% CI 6.29-13.30) and better quality of life (differences of least squares means 29.86, 95% CI 22.33-37.38). Logistic regression analysis showed a positive effect of the de qi score on facial-nerve function (adjusted OR 1.07, 95% CI 1.04-1.09). INTERPRETATION: Among patients with Bell palsy, acupuncture with strong stimulation that elicited de qi had a greater therapeutic effect, and stronger intensity of de qi was associated with the better therapeutic effects. Trial registration: Clinicaltrials.gov no. NCT00685789.  
  Address  
  Publisher
  Language Number of Treatments 20  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants (down) 338  
  Time in Treatment 4 Weeks Condition Bell Palsy
  Disease Category Cranial Nerve Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 1350  
Permanent link to this record
 

 
Author Coulon, C.; Poleszczuk, M.; Paty-Montaigne, M. H.; Gascard, C.; Gay, C.; Houfflin-Debarge, V.; Subtil, D. url  doi
openurl 
  Title Version of breech fetuses by moxibustion with acupuncture: a randomized controlled trial Type of Study RCT
  Year 2014 Publication Obstetrics and gynecology Abbreviated Journal Obstet Gynecol  
  Volume 124 Issue 1 Pages 32-39  
  Keywords RCT; Pregnancy Complications; Breech Presentation; Acu Versus Sham; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture + Other; Indirect Moxibustion; Moxa; Sham Control; Non Penetrating Sham, Laser; Verum Acupoint Control  
  Abstract OBJECTIVE: To assess the efficacy of moxibustion (heating of the acupuncture needle with an igniting charcoal moxa stick) with acupuncture for version of breech presentations after 33 4/7 weeks of gestation to reduce their rate at 37 weeks of gestation and at delivery. METHODS: This was a randomized placebo-controlled single-blind trial including 328 pregnant women recruited in a university hospital center between 33 4/7 and 35 4/7 weeks of gestation. Moxibustion with acupuncture or inactivated laser (placebo) treatment was applied to point BL 67 for six sessions. The principal endpoint was the percentage of fetuses in breech presentation at 37 2/7 weeks of gestation. RESULTS: The study included 328 women randomized into two groups: moxibustion with acupuncture (n=164) or placebo (n=164). The percentage of fetuses in breech presentation at 37 2/7 weeks of gestation was not significantly different in both groups (72.0 in the moxibustion with acupuncture group compared with 63.4% in the placebo group, relative risk 1.13, 95% confidence interval 0.98-1.32, P=.10). CONCLUSION: Treatment by moxibustion with acupuncture was not effective in correcting breech presentation in the third trimester of pregnancy. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT01487590.  
  Address Hopital Jeanne de Flandre, Universite Lille II, Faculte de medecine Henri Warembourg, Universite Lille 2, UPRES Lille Nord de France, and EA2694, UDSL, University Lille Nord de France, Lille, France.  
  Publisher
  Language Number of Treatments 6  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants (down) 328  
  Time in Treatment 2 Weeks Condition Breech Presentation
  Disease Category Pregnancy Complications OCSI Score  
  Notes Approved no  
  Call Number Serial 209  
Permanent link to this record
 

 
Author Wang, C.; Li, S. openurl 
  Title Clinical study on treatment of knee osteoarthritis with combined acupuncture and medication Type of Study RCT
  Year 2009 Publication Journal of Acupuncture and Tuina Science Abbreviated Journal J Acupunct Tuina Sci  
  Volume 7 Issue 6 Pages 354-356  
  Keywords AcuTrials; RCT; Arthritis; Osteoarthritis, Knee; Acu Versus CAM Control; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture + Other; CAM Control; Herbal Formula  
  Abstract OBJECTIVE: To observe the effect of treatment for proliferative knee osteoarthritis (KOA) using combined acupuncture and medicated compression. METHOD: All 328 cases were randomized into an observation and control group, 164 cases in each. Combined acupuncture and medicated compression were adopted in the observation group, while oral administration of Zhui Feng Tou Gu Wan (Wind-Removing and Bone-Penetrating Pills) were adopted in the control group. The clinical effects in the two groups were evaluated 40 days after the treatment. RESULTS: There were significant differences in both marked and total effective rates (P<0.05). CONCLUSION: Combined acupuncture and medicated compression can obtain better effect for KOA than oral administration of the Wind-removing and Bone-Penetrating Pills.  
  Address  
  Publisher
  Language Number of Treatments 20  
  Treatment Follow-up 6 Weeks Frequency >1/WK Number of Participants (down) 328  
  Time in Treatment 6 Weeks Condition Osteoarthritis, Knee
  Disease Category Arthritis OCSI Score  
  Notes Approved no  
  Call Number Serial 1235  
Permanent link to this record
 

 
Author Yang, X.; Xu, S.; Wei. J. openurl 
  Title External Application of Chinese Medicine following Tapping Using a Plum-blossom Needle for Allergic Rhinitis. Type of Study RCT
  Year 2010 Publication Journal of Acupuncture and Tuina Science Abbreviated Journal J Acupunct Tuina Sci  
  Volume 8 Issue 2 Pages 98-101  
  Keywords Respiratory Tract Diseases; Rhinitis, Allergic; Allergies; RCT; Semi-Individualized Acupuncture Protocol; Symptom Based Point Selection; Acu Versus > 1 Control; CAM Control; Herbal Formula; Plum-Blossom; TCM Acupuncture Style; AcuTrials; Acupuncture  
  Abstract Objecitve: To observe the clinical efficacy of external application of Chinese medicine following tapping using a plum-blossom needle for allergic rhinitis. Methods: All 328 cases were randomized into an observation group of 206 cases, Chinese medicine group of 70 cases and point application group of 52 cases. Results: The differences between the observation and CHinese medicine groups (P<0.01) and between the observation and point application group )P<0.05) were both of statistical meaning. The cases in the observation obtained the best effect, the point application group obtained a moderate effect and the Chinese medicne group obtained the least effect. A younger age and an increased number of treatment s contributed to a btter effect. Conclusion:External application of Chinese medicine following tapping using a plum-blossom needle is safge and effective of allergic rhinitis.  
  Address Hospital of Laigang Group Co., Ltd., Laiwu, Shandong 271126 P.R. China  
  Publisher
  Language Number of Treatments 3  
  Treatment Follow-up N/A Frequency <1/WK Number of Participants (down) 328  
  Time in Treatment 4 Weeks Condition Rhinitis, Allergic
  Disease Category Respiratory Tract Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 1372  
Permanent link to this record
 

 
Author Kawakita, K.; Shichidou, T.; Inoue, E.; Nabeta, T.; Kitakouji, H.; Aizawa, S.; Nishida, A.; Yamaguchi, N.; Takahashi, N.; Yano, T.; Tanzawa, S. url  openurl
  Title Preventive and curative effects of acupuncture on the common cold: a multicentre randomized controlled trial in Japan Type of Study RCT
  Year 2004 Publication Complementary therapies in medicine Abbreviated Journal Complement Ther Med  
  Volume 12 Issue 4 Pages 181-188  
  Keywords Acu Versus No Treatment; Acupuncture; AcuTrials; Common Cold; Japanese Acupuncture Style; No Treatment Control; RCT; Respiratory Tract Diseases; Fixed Acupuncture Protocol  
  Abstract OBJECTIVE:: To determine the preventive and curative effects of manual acupuncture on the symptoms of the common cold. METHOD:: Students and staff in five Japanese acupuncture schools (n=326) were randomly allocated to acupuncture and no-treatment control groups. A specific needling point (Y point) on the neck was used bilaterally. Fine acupuncture needles were gently manipulated for 15s, evoking de qi sensation. Acupuncture treatments were performed four times during the 2-week experimental period with a 2-week follow-up period. A common cold diary was scored daily for 4 weeks, and a common cold questionnaire was scored before each acupuncture treatment and twice at weekly intervals. A reliability test for the questionnaire was performed on the last day of recording. RESULTS:: Five of the 326 subjects who were recruited dropped out. The diary score in the acupuncture group tended to decrease after treatment, but the difference between groups was not significant (Kaplan-Meier survival analysis, log rank test P=0.53, Cox regression analysis, P>0.05). Statistically significantly fewer symptoms were reported in the questionnaire by the acupuncture group than control group (P=0.024, general linear model, repeated measure). Significant inter-centre (P<0.001, general linear model) and sex (P=0.027, general linear model) differences were also detected. Reliability tests indicated that the questionnaire with 15 items was sufficiently reliable. No severe adverse event was reported. CONCLUSION:: This is the first report of a multi-centre randomized controlled trial of acupuncture for symptoms of the common cold. A significantly positive effect of acupuncture was demonstrated in the summed questionnaire data, although a highly significant inter-centre difference was observed. Needling on the neck using the Japanese fine needle manipulating technique was shown to be effective and safe. The use of acupuncture for symptoms of the common cold symptoms should be considered, although further evidence from placebo controlled RCTs is required  
  Address Japan Acupuncture and Moxibustion Center, 3-44-14 Minami otsuka, Toshima-ku, Tokyo 170-0005, Japan  
  Publisher
  Language Number of Treatments 4  
  Treatment Follow-up 2 Weeks Frequency >1/WK Number of Participants (down) 326  
  Time in Treatment 2 Weeks Condition Common Cold
  Disease Category Respiratory Tract Diseases OCSI Score 62  
  Notes Approved no  
  Call Number Serial 558  
Permanent link to this record
 

 
Author Dos Santos Maciel, L.Y.; Dos Santos Leite, P.M.; Neto, M.L.P.; Mendonca, A.C.R.; de Araujo, C.C.A.; da Hora Santos Souza, J.; DeSantana, J.M. url  doi
openurl 
  Title Comparison of the placebo effect between different non-penetrating acupuncture devices and real acupuncture in healthy subjects: a randomized clinical trial Type of Study RCT
  Year 2016 Publication BMC Complementary and Alternative Medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 16 Issue 1 Pages 518  
  Keywords AcuTrials; RCT; Healthy Subjects; Acupuncture; Placebo; Acu Versus > 1 Control; Fixed Acupuncture Protocol; Acupuncture Only; Sham Control; Non Penetrating Sham, Mechanical; Verum Acupoint Control  
  Abstract BACKGROUND: Several studies have used placebo acupuncture methods in recent years as a way for blinding therapeutic effect of acupuncture, however placebo method selection has not followed enough methodological criteria to the point of stabilishing a consensus of what should be the best method to be used. This study aimed to evaluate the effectiveness of three different placebo acupuncture methods for blinding applied in healthy subjects. METHODS: This study was approved by the Ethics Committee of the Federal University of Sergipe with the number 47193015.5.0000.5546 and all individuals participating in the study signed a free and informed consent. For this study, 321 healthy volunteers were randomly divided into seven groups using the abdominal point stomach (ST) 25 and seven groups using the lumbar point bladder (Bl) 52 for stimulation. For real acupuncture procedure, three different methods of placebo acupuncture plus a mix between real acupuncture and placebo applied in the same individual, totaling fourteen groups in this study. Outcome assessments were performed before and immediately after applying the technique. Investigator who assessed variables had no knowledgement about the method was applied. Identification, weight and height were measured before puncture by using. At the end, subjects were asked if they believed they were receiving real or placebo acupuncture. RESULTS: There was no significant difference between groups for the perception about the type o stimulation (wheter real or placebo puncture). Percentage of subjects who reported to have received real acupuncture in the abdominal point was 69.56% in real group, 86.95% in group Park Sham, 82.60% in needle + foam, 91.30% in insertion and removal, 78.26% in real + Park Sham, 86.36% in real + needle and foam, 86.95% in real + insertion and removal, and for the lumbar point was 86.36% in real group, 86.95% in group Park Sham, 69.56% in needle + foam, 72% in insertion and removal, 86.95% in real + Park Sham, 81.81% in real + needle and foam and 78.26% in real + insertion and removal. CONCLUSION: All placebo acupuncture methods proposed in this study were equally effective for bliding the study participants using either abdominal or lumbar acupoints, and none of the placebo methods presented benefit compared to the other to be used in future clinical trials. ETHICS COMMITTEE: Federal University of Sergipe (UFS), number of approval: 47193015.5.0000.5546 TRIAL REGISTRATION: ensaiosclinicos.gov.br RBR-3w2p32 Registered in 28th January 2016.  
  Address Professor of the Department of Physical Therapy and Post Graduate Programs in Health Sciences and Physiological Sciences, Federal University of Sergipe, Rua Claudio Batista, s/n. Bairro Santo Antonio, CEP 49060-100, Aracaju, Sergipe, Brasil. desantana@pq.cnpq.br  
  Publisher
  Language English Number of Treatments 1  
  Treatment Follow-up Frequency N/A Number of Participants (down) 321  
  Time in Treatment 1 Day Condition Healthy Subjects
  Disease Category Healthy Subjects OCSI Score  
  Notes PMID:27978834; PMCID:PMC5159982 Approved yes  
  Call Number OCOM @ refbase @ Serial 2190  
Permanent link to this record
 

 
Author Konefal, J.; Duncan, R.; Clemence, C. url  openurl
  Title The impact of the addition of an acupuncture treatment program to an existing metro-Dade County outpatient substance abuse treatment facility Type of Study RCT
  Year 1994 Publication Journal of addictive diseases Abbreviated Journal J Addict Dis  
  Volume 13 Issue 3 Pages 71-99  
  Keywords Acu Versus > 1 Control; AcuTrials; Drug Addiction; Auricular Acupuncture; Counseling; Group Acupuncture Style; NADA Protocol Acupuncture Style; RCT; Restricted Modalities, Acupuncture Only; Semi-Individualized Acupuncture Protocol; Usual Care Control, Educational; Substance Abuse; Symptom Based Point Selection; Substance-Related Disorders  
  Abstract There are several varieties of treatment facilities and modalities for dealing with substance abuse. In this study, the addition of acupuncture treatments to the usual care program at an existing county-based substance abuse treatment clinic was tested. Men and women who voluntarily attended the clinic or who were remanded by the court to attend were randomized to receive usual care, usual care plus frequent urine testing, or usual care plus frequent urine testing and acupuncture treatments. Clients who received acupuncture treatments in addition to the usual care and frequent urine testing became clean (as measured by negative urine tests) in 57% of the time required for the frequent urine testing group. Difficulties experienced included low counselor compliance with the protocol and a high drop-out rate, indicating that further research is necessary; however, this study demonstrates that acupuncture can be a feasible and effective addition to existing drug treatment programs  
  Address Department of Psychiatry, University of Miami School of Medicine, FL 33136, USA  
  Publisher
  Language Number of Treatments 48  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants (down) 304  
  Time in Treatment 16 Weeks Condition Substance-Related Disorders
  Disease Category Substance-Related Disorders OCSI Score  
  Notes Approved no  
  Call Number Serial 595  
Permanent link to this record
 

 
Author Vixner, L.; Schytt, E.; Stener-Victorin, E.; Waldenstrom, U.; Pettersson, H.; Martensson, L. B. url  doi
openurl 
  Title Acupuncture with manual and electrical stimulation for labour pain: a longitudinal randomised controlled trial Type of Study RCT
  Year 2014 Publication BMC complementary and alternative medicine Abbreviated Journal BMC Complement Altern Med  
  Volume 14 Issue 187 Pages -  
  Keywords RCT; Pain; Labor Pain; Acu + Usual Care Versus > 1 Control; Acupuncture; Electroacupuncture; TCM Acupuncture Style; Semi-Individualized Acupuncture Protocol; Symptom Based Point Selection; Restricted Modalities, Acupuncture Only; CAM Control; Acu Versus Acu; Usual Care Control, Pharmaceutical; Pregnancy  
  Abstract BACKGROUND: Acupuncture is commonly used to reduce pain during labour despite contradictory results. The aim of this study is to evaluate the effectiveness of acupuncture with manual stimulation and acupuncture with combined manual and electrical stimulation (electro-acupuncture) compared with standard care in reducing labour pain. Our hypothesis was that both acupuncture stimulation techniques were more effective than standard care, and that electro-acupuncture was most effective. METHODS: A longitudinal randomised controlled trial. The recruitment of participants took place at the admission to the labour ward between November 2008 and October 2011 at two Swedish hospitals . 303 nulliparous women with normal pregnancies were randomised to: 40 minutes of manual acupuncture (MA), electro-acupuncture (EA), or standard care without acupuncture (SC). Primary outcome: labour pain, assessed by Visual Analogue Scale (VAS). Secondary outcomes: relaxation, use of obstetric pain relief during labour and post-partum assessments of labour pain. The sample size calculation was based on the primary outcome and a difference of 15 mm on VAS was regarded as clinically relevant, this gave 101 in each group, including a total of 303 women. RESULTS: Mean estimated pain scores on VAS (SC: 69.0, MA: 66.4 and EA: 68.5), adjusted for: treatment, age, education, and time from baseline, with no interactions did not differ between the groups (SC vs MA: mean difference 2.6, 95% confidence interval [CI] -1.7-6.9 and SC vs EA: mean difference 0.6 [95% CI] -3.6-4.8). Fewer number of women in the EA group used epidural analgesia (46%) than women in the MA group (61%) and SC group (70%) (EA vs SC: odds ratio [OR] 0.35; [95% CI] 0.19-0.67). CONCLUSIONS: Acupuncture does not reduce women's experience of labour pain, neither with manual stimulation nor with combined manual and electrical stimulation. However, fewer women in the EA group used epidural analgesia thus indicating that the effect of acupuncture with electrical stimulation may be underestimated. These findings were obtained in a context with free access to other forms of pain relief. TRIAL REGISTRATION: ClinicalTrials.gov: NCT01197950.  
  Address Department of Women's and Children's Health, Division of Reproductive Health, Karolinska Institutet, Retzius vag 13A, 171 77 Stockholm, Sweden. linda.vixner@ki.se.  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up N/A Frequency N/A Number of Participants (down) 303  
  Time in Treatment 1 Day Condition Labor Pain
  Disease Category Pain OCSI Score  
  Notes Approved no  
  Call Number Serial 1222  
Permanent link to this record
 

 
Author Linde, K.; Streng, A.; Hoppe, A.; Brinkhaus, B.; Witt, C. M.; Hammes, M.; Irnich, D.; Hummelsberger, J.; Willich, S. N.; Melchart, D. url  openurl
  Title Treatment in a Randomized Multicenter Trial of Acupuncture for Migraine (ART Migraine) Type of Study RCT
  Year 2006 Publication Abbreviated Journal Forsch Komplementmed  
  Volume 13 Issue 2 Pages 101-108  
  Keywords CAM Control; Acu Versus > 1 Control; Acupuncture; AcuTrials; Headache Disorders; Penetrating Sham; Migraine; RCT; Restricted Modalities, Acupuncture Only; Semi-Individualized Acupuncture Protocol; Superficial Needling Depth; Sham Control; Traditional Diagnosis Based Point Selection; TCM Acupuncture Style; Verum Acupoint Control; Wait-List Control  
  Abstract Background: This paper aims to describe the characteristics of physicians and interventions of a large, multicenter randomized trial of acupuncture for migraine (ART Migraine) in order to enable acupuncturists to assess the study interventions. Patients and Methods: 302 patients suffering from migraine were randomized to 12 sessions of semi-standardized acupuncture (6 predefined basic points, recommendations for optional individual choice of additional points given), standardized minimal acupuncture (superficial needling of at least 5 of 10 predefined, distant non-acupuncture points) or a waiting list. 30 physicians trained and experienced in acupuncture from 18 centers in Germany participated in the trial. Results: The median duration of acupuncture training of trial physicians was 500 h (range 140-1350). Physicians had acupuncture experience for 10 (<1 to 25) years and had treated 200 (60 to >1000) patients with acupuncture in the year preceding trial participation. The 6 basic points were needled in 76-93% of sessions. Compliance with treatment instructions varied considerably among centers in the acupuncture group. In contrast, compliance with the minimal acupuncture protocol was very good. 6 of the 30 physicians stated that they would have treated patients somewhat differently outside the trial, 1 completely differently. The trial found a significant effect of those treated with acupuncture compared to those on the waiting list for treatment, but minimal acupuncture was as effective as acupuncture. Conclusions: The treatment protocols for acupuncture and minimal acupuncture in ART Migraine appeared an adequate compromise in the specific situation and for the predefined purposes. However, a relevant minority of participating physicians would have treated patients differently outside the trial  
  Address Centre for Complementary Medicine Research, Department of Internal Medicine II, Technical University of Munich, Germany  
  Publisher
  Language Number of Treatments 12  
  Treatment Follow-up 12 Weeks Frequency >1/WK Number of Participants (down) 302  
  Time in Treatment 8 Weeks Condition Migraine
  Disease Category Headache Disorders OCSI Score  
  Notes Approved no  
  Call Number Serial 727  
Permanent link to this record
 

 
Author Linde, K.; Streng, A.; Jurgens, S.; Hoppe, A.; Brinkhaus, B.; Witt, C.; Wagenpfeil, S.; Pfaffenrath, V.; Hammes, M. G.; Weidenhammer, W.; Willich, S. N.; Melchart, D. url  openurl
  Title Acupuncture for patients with migraine: a randomized controlled trial Type of Study RCT
  Year 2005 Publication Abbreviated Journal JAMA  
  Volume 293 Issue 17 Pages 2118-2125  
  Keywords Acu Versus > 1 Control; Acupuncture; AcuTrials; Penetrating Sham; Migraine; Pain; RCT; Restricted Modalities, Acupuncture Only; Semi-Individualized Acupuncture Protocol; Superficial Needling Depth; Sham Acupoint Control; Sham Control; Symptom Based Point Selection; TCM Acupuncture Style; Wait-List Control; Headache Disorders;  
  Abstract CONTEXT: Acupuncture is widely used to prevent migraine attacks, but the available evidence of its benefit is scarce. OBJECTIVE: To investigate the effectiveness of acupuncture compared with sham acupuncture and with no acupuncture in patients with migraine. DESIGN, SETTING, AND PATIENTS: Three-group, randomized, controlled trial (April 2002-January 2003) involving 302 patients (88% women), mean (SD) age of 43 (11) years, with migraine headaches, based on International Headache Society criteria. Patients were treated at 18 outpatient centers in Germany. INTERVENTIONS: Acupuncture, sham acupuncture, or waiting list control. Acupuncture and sham acupuncture were administered by specialized physicians and consisted of 12 sessions per patient over 8 weeks. Patients completed headache diaries from 4 weeks before to 12 weeks after randomization and from week 21 to 24 after randomization. MAIN OUTCOME MEASURES: Difference in headache days of moderate or severe intensity between the 4 weeks before and weeks 9 to 12 after randomization. RESULTS: Between baseline and weeks 9 to 12, the mean (SD) number of days with headache of moderate or severe intensity decreased by 2.2 (2.7) days from a baseline of 5.2 (2.5) days in the acupuncture group compared with a decrease to 2.2 (2.7) days from a baseline of 5.0 (2.4) days in the sham acupuncture group, and by 0.8 (2.0) days from a baseline if 5.4 (3.0) days in the waiting list group. No difference was detected between the acupuncture and the sham acupuncture groups (0.0 days, 95% confidence interval, -0.7 to 0.7 days; P = .96) while there was a difference between the acupuncture group compared with the waiting list group (1.4 days; 95% confidence interval; 0.8-2.1 days; P<.001). The proportion of responders (reduction in headache days by at least 50%) was 51% in the acupuncture group, 53% in the sham acupuncture group, and 15% in the waiting list group. CONCLUSION: Acupuncture was no more effective than sham acupuncture in reducing migraine headaches although both interventions were more effective than a waiting list control  
  Address Centre for Complementary Medicine Research, Department of Internal Medicine II, Technische Universitat Munchen, Munich, Germany. Klaus.Linde@lrz.tu-muenchen.de  
  Publisher
  Language Number of Treatments 12  
  Treatment Follow-up 16 Weeks Frequency >1/WK Number of Participants (down) 302  
  Time in Treatment 8 Weeks Condition Migraine
  Disease Category Headache Disorders OCSI Score 90  
  Notes Approved no  
  Call Number Serial 729  
Permanent link to this record
Select All    Deselect All
 |   | 
Details
   print

Save Citations:
Export Records: