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  Records Links
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2487  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2528  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2569  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2610  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2666  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2707  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2733  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2774  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2815  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2856  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2897  
Permanent link to this record
 

 
Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages (down) e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2938  
Permanent link to this record
 

 
Author Essex, H.; Parrott, S.; Atkin, K.; Ballard, K.; Bland, M.; Eldred, J.; Hewitt, C.; Hopton, A.; Keding, A.; Lansdown, H.; Richmond, S.; Tilbrook, H.; Torgerson, D.; Watt, I.; Wenham, A.; Woodman, J.; MacPherson, H. url  doi
openurl 
  Title An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS) Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 12 Pages (down) e0178918  
  Keywords Acupuncture/economics/*methods; Age Factors; Chronic Pain/*therapy; *Cost-Benefit Analysis; Female; Humans; Male; *Movement; Musculoskeletal Manipulations/economics/*methods; Neck Pain/*therapy; Primary Health Care  
  Abstract OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). RESULTS: In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were pound451 for acupuncture and pound667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = pound18,767/QALY bootstrapped 95% CI pound4,426 to pound74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of pound20,000/QALY ( pound25,101/QALY bootstrapped 95% CI – pound150,208 to pound248,697) but may be at pound30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. CONCLUSIONS: In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.  
  Address Department of Health Sciences, University of York, York, United Kingdom  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29211741; PMCID:PMC5718562 Approved no  
  Call Number OCOM @ refbase @ Serial 2441  
Permanent link to this record
 

 
Author Essex, H.; Parrott, S.; Atkin, K.; Ballard, K.; Bland, M.; Eldred, J.; Hewitt, C.; Hopton, A.; Keding, A.; Lansdown, H.; Richmond, S.; Tilbrook, H.; Torgerson, D.; Watt, I.; Wenham, A.; Woodman, J.; MacPherson, H. url  doi
openurl 
  Title An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS) Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 12 Pages (down) e0178918  
  Keywords Acupuncture/economics/*methods; Age Factors; Chronic Pain/*therapy; *Cost-Benefit Analysis; Female; Humans; Male; *Movement; Musculoskeletal Manipulations/economics/*methods; Neck Pain/*therapy; Primary Health Care  
  Abstract OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). RESULTS: In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were pound451 for acupuncture and pound667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = pound18,767/QALY bootstrapped 95% CI pound4,426 to pound74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of pound20,000/QALY ( pound25,101/QALY bootstrapped 95% CI – pound150,208 to pound248,697) but may be at pound30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. CONCLUSIONS: In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.  
  Address Department of Health Sciences, University of York, York, United Kingdom  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29211741; PMCID:PMC5718562 Approved no  
  Call Number OCOM @ refbase @ Serial 2482  
Permanent link to this record
 

 
Author Essex, H.; Parrott, S.; Atkin, K.; Ballard, K.; Bland, M.; Eldred, J.; Hewitt, C.; Hopton, A.; Keding, A.; Lansdown, H.; Richmond, S.; Tilbrook, H.; Torgerson, D.; Watt, I.; Wenham, A.; Woodman, J.; MacPherson, H. url  doi
openurl 
  Title An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS) Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 12 Pages (down) e0178918  
  Keywords Acupuncture/economics/*methods; Age Factors; Chronic Pain/*therapy; *Cost-Benefit Analysis; Female; Humans; Male; *Movement; Musculoskeletal Manipulations/economics/*methods; Neck Pain/*therapy; Primary Health Care  
  Abstract OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). RESULTS: In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were pound451 for acupuncture and pound667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = pound18,767/QALY bootstrapped 95% CI pound4,426 to pound74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of pound20,000/QALY ( pound25,101/QALY bootstrapped 95% CI – pound150,208 to pound248,697) but may be at pound30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. CONCLUSIONS: In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.  
  Address Department of Health Sciences, University of York, York, United Kingdom  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29211741; PMCID:PMC5718562 Approved no  
  Call Number OCOM @ refbase @ Serial 2523  
Permanent link to this record
 

 
Author Essex, H.; Parrott, S.; Atkin, K.; Ballard, K.; Bland, M.; Eldred, J.; Hewitt, C.; Hopton, A.; Keding, A.; Lansdown, H.; Richmond, S.; Tilbrook, H.; Torgerson, D.; Watt, I.; Wenham, A.; Woodman, J.; MacPherson, H. url  doi
openurl 
  Title An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS) Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 12 Pages (down) e0178918  
  Keywords Acupuncture/economics/*methods; Age Factors; Chronic Pain/*therapy; *Cost-Benefit Analysis; Female; Humans; Male; *Movement; Musculoskeletal Manipulations/economics/*methods; Neck Pain/*therapy; Primary Health Care  
  Abstract OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). RESULTS: In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were pound451 for acupuncture and pound667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = pound18,767/QALY bootstrapped 95% CI pound4,426 to pound74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of pound20,000/QALY ( pound25,101/QALY bootstrapped 95% CI – pound150,208 to pound248,697) but may be at pound30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. CONCLUSIONS: In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.  
  Address Department of Health Sciences, University of York, York, United Kingdom  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29211741; PMCID:PMC5718562 Approved no  
  Call Number OCOM @ refbase @ Serial 2564  
Permanent link to this record
 

 
Author Essex, H.; Parrott, S.; Atkin, K.; Ballard, K.; Bland, M.; Eldred, J.; Hewitt, C.; Hopton, A.; Keding, A.; Lansdown, H.; Richmond, S.; Tilbrook, H.; Torgerson, D.; Watt, I.; Wenham, A.; Woodman, J.; MacPherson, H. url  doi
openurl 
  Title An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS) Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 12 Pages (down) e0178918  
  Keywords Acupuncture/economics/*methods; Age Factors; Chronic Pain/*therapy; *Cost-Benefit Analysis; Female; Humans; Male; *Movement; Musculoskeletal Manipulations/economics/*methods; Neck Pain/*therapy; Primary Health Care  
  Abstract OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). RESULTS: In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were pound451 for acupuncture and pound667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = pound18,767/QALY bootstrapped 95% CI pound4,426 to pound74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of pound20,000/QALY ( pound25,101/QALY bootstrapped 95% CI – pound150,208 to pound248,697) but may be at pound30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. CONCLUSIONS: In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.  
  Address Department of Health Sciences, University of York, York, United Kingdom  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29211741; PMCID:PMC5718562 Approved no  
  Call Number OCOM @ refbase @ Serial 2605  
Permanent link to this record
 

 
Author Essex, H.; Parrott, S.; Atkin, K.; Ballard, K.; Bland, M.; Eldred, J.; Hewitt, C.; Hopton, A.; Keding, A.; Lansdown, H.; Richmond, S.; Tilbrook, H.; Torgerson, D.; Watt, I.; Wenham, A.; Woodman, J.; MacPherson, H. url  doi
openurl 
  Title An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS) Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 12 Pages (down) e0178918  
  Keywords Acupuncture/economics/*methods; Age Factors; Chronic Pain/*therapy; *Cost-Benefit Analysis; Female; Humans; Male; *Movement; Musculoskeletal Manipulations/economics/*methods; Neck Pain/*therapy; Primary Health Care  
  Abstract OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). RESULTS: In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were pound451 for acupuncture and pound667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = pound18,767/QALY bootstrapped 95% CI pound4,426 to pound74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of pound20,000/QALY ( pound25,101/QALY bootstrapped 95% CI – pound150,208 to pound248,697) but may be at pound30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. CONCLUSIONS: In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.  
  Address Department of Health Sciences, University of York, York, United Kingdom  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29211741; PMCID:PMC5718562 Approved no  
  Call Number OCOM @ refbase @ Serial 2647  
Permanent link to this record
 

 
Author Essex, H.; Parrott, S.; Atkin, K.; Ballard, K.; Bland, M.; Eldred, J.; Hewitt, C.; Hopton, A.; Keding, A.; Lansdown, H.; Richmond, S.; Tilbrook, H.; Torgerson, D.; Watt, I.; Wenham, A.; Woodman, J.; MacPherson, H. url  doi
openurl 
  Title An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS) Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 12 Pages (down) e0178918  
  Keywords Acupuncture/economics/*methods; Age Factors; Chronic Pain/*therapy; *Cost-Benefit Analysis; Female; Humans; Male; *Movement; Musculoskeletal Manipulations/economics/*methods; Neck Pain/*therapy; Primary Health Care  
  Abstract OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). RESULTS: In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were pound451 for acupuncture and pound667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = pound18,767/QALY bootstrapped 95% CI pound4,426 to pound74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of pound20,000/QALY ( pound25,101/QALY bootstrapped 95% CI – pound150,208 to pound248,697) but may be at pound30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. CONCLUSIONS: In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.  
  Address Department of Health Sciences, University of York, York, United Kingdom  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29211741; PMCID:PMC5718562 Approved no  
  Call Number OCOM @ refbase @ Serial 2688  
Permanent link to this record
 

 
Author Essex, H.; Parrott, S.; Atkin, K.; Ballard, K.; Bland, M.; Eldred, J.; Hewitt, C.; Hopton, A.; Keding, A.; Lansdown, H.; Richmond, S.; Tilbrook, H.; Torgerson, D.; Watt, I.; Wenham, A.; Woodman, J.; MacPherson, H. url  doi
openurl 
  Title An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS) Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 12 Pages (down) e0178918  
  Keywords Acupuncture/economics/*methods; Age Factors; Chronic Pain/*therapy; *Cost-Benefit Analysis; Female; Humans; Male; *Movement; Musculoskeletal Manipulations/economics/*methods; Neck Pain/*therapy; Primary Health Care  
  Abstract OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). RESULTS: In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were pound451 for acupuncture and pound667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = pound18,767/QALY bootstrapped 95% CI pound4,426 to pound74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of pound20,000/QALY ( pound25,101/QALY bootstrapped 95% CI – pound150,208 to pound248,697) but may be at pound30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. CONCLUSIONS: In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.  
  Address Department of Health Sciences, University of York, York, United Kingdom  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29211741; PMCID:PMC5718562 Approved no  
  Call Number OCOM @ refbase @ Serial 2728  
Permanent link to this record
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