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Author Itoh, K.; Itoh, S.; Katsumi, Y.; Kitakoji, H. url  openurl
  Title (up) A pilot study on using acupuncture and transcutaneous electrical nerve stimulation to treat chronic non-specific low back pain Type of Study RCT
  Year 2009 Publication Complement Abbreviated Journal Complement  
  Volume 15 Issue 1 Pages 22-25  
  Keywords TENS; CAM Control; Acu Versus > 1 Control; Acupuncture; AcuTrials; Back Pain; Low Back Pain, Chronic; Fixed Acupuncture Protocol; Low Back Pain; Pain; Pilot Study; RCT; Restricted Modalities, Acupuncture + Other; Restricted Modalities, Acupuncture Only; TCM Acupuncture Style; TENS; Transcutaneous Electric Nerve Stimulation  
  Abstract OBJECTIVE: The present study tests whether a combined treatment of acupuncture and transcutaneous electrical nerve stimulation (TENS) is more effective than acupuncture or TENS alone for treating chronic low back pain (LBP). METHODS: Thirty-two patients with chronic LBP were randomly allocated to four groups. The acupuncture group (ACP) received only acupuncture treatment at selected acupoints for low back pain; the TENS group (TENS) received only TENS treatment at pain areas; the acupuncture and TENS group (A&T) received both acupuncture and TENS treatments; the control group (CT) received topical poultice (only when necessary). Each group received specific weekly treatment five times during the study. Outcome measures were pain intensity in terms of visual analogue scale (VAS) and QOL of low back in terms of Roland-Morris Disability Questionnaire (RDQ). RESULTS: The ACP, TENS and A&T groups all reported lower VAS and RDQ scores. Significant reduction in pain intensity (P<0.008) and significant improvement in QOL (P<0.008) were shown in the A&T group. CONCLUSION: Combined acupuncture and TENS treatment is effective in pain relief and QOL of low back improvement for the sampled patients suffering from chronic LBP  
  Address Department of Clinical Acupuncture and Moxibustion, Meiji University of Integrative Medicine, Kyoto 629-0392, Japan  
  Publisher
  Language Number of Treatments 5  
  Treatment Follow-up 10 Weeks Frequency 1/WK Number of Participants 32  
  Time in Treatment 5 Weeks Condition Low Back Pain, Chronic
  Disease Category Back Pain OCSI Score  
  Notes Approved no  
  Call Number Serial 507  
Permanent link to this record
 

 
Author Ritenbaugh, C.; Hammerschlag, R.; Calabrese, C.; Mist, S.; Aickin, M.; Sutherland, E.; Leben, J.; DeBar, L.; Elder, C.; Dworkin, S. F. url  openurl
  Title (up) A pilot whole systems clinical trial of traditional chinese medicine and naturopathic medicine for the treatment of temporomandibular disorders Type of Study RCT
  Year 2008 Publication Abbreviated Journal J Altern Complement Med  
  Volume 14 Issue 5 Pages 475-487  
  Keywords CAM Control; Acu Versus > 1 Control; Acupuncture; AcuTrials; Facial Pain; Herbal Formula; Manualized Acupuncture Protocol; Massage; Naturopathy; Pain; Pilot Study; RCT; Restricted Modalities, Acupuncture + Other; Usual Care Control, Multimodality; TCM Acupuncture Style; Temporomandibular Joint Disorders; Temporomandibular Joint Dysfunction Syndrome; Traditional Diagnosis Based Point Selection; Tuina; Stomatognathic Diseases; TMD; TMJ  
  Abstract OBJECTIVES: To assess the feasibility and acceptability of studying whole systems of Traditional Chinese Medicine (TCM) and Naturopathic medicine (NM) in the treatment of temporomandibular disorders (TMD), and to determine whether there is indication to support further research. DESIGN: A pilot study using a randomized controlled clinical trial design of whole system TCM and NM versus state-of-the-art specialty care (SC). SETTING/LOCATION: Kaiser Permanente Northwest (KPNW), and practitioner offices in Portland, Oregon. SUBJECTS: One hundred and sixty (160) women 25-55 years of age attending a KPNW TMD specialty clinic. INTERVENTIONS: Whole system TCM and NM, and KPNW TMD clinic SC; the intervention protocols were designed to model the individually tailored type of community care offered in alternative medicine practices in Portland and in the KPNW TMD clinic, using protocols that enhanced similarities among practitioners within each system and permitted full descriptions of the treatments provided. OUTCOME MEASURES: TMD was ascertained using the Research Diagnostic Criteria/TMD; outcomes were self-reported worst and average facial pain and interference with activities (scaled 0-10 where 10 is worst). RESULTS: Of 948 consecutive eligible patients, 160 were randomized to one of three arms; 128 provided endpoint data. TCM and NM demonstrated significantly greater in-treatment reductions for worst facial pain compared to SC (adjusted regression analysis; higher negative values indicate greater improvement, = -1.11 +/- 0.43, p = 0.010 and -1.02 +/- 0.45, p = 0.025 for TCM and NM, respectively, compared to SC) and at 3 months post-treatment (-1.07 +/- 0.51, p = 0.037 and -1.27 +/- 0.54, p = 0.019 for TCM and NM versus SC, respectively). Additionally, TCM provided significantly greater decreases in average pain than SC; NM provided significantly greater decreases than SC or TCM in TMD-related psychosocial interference. CONCLUSIONS: These alternative medicine approaches each resulted in significantly greater reduction of pain and psychosocial interference than SC. Further research on the potential benefits of traditional whole systems of medicine for TMD appears warranted  
  Address Department of Family and Community Medicine, The University of Arizona, Tucson, AZ 85719, USA. ritenbau@email.arizona.edu  
  Publisher
  Language Number of Treatments 19  
  Treatment Follow-up 24 Weeks Frequency >1/WK Number of Participants 160  
  Time in Treatment 14 Weeks Condition Temporomandibular Joint Dysfunction Syndrome
  Disease Category Stomatognathic Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 993  
Permanent link to this record
 

 
Author Chen, S.; Zhang, B.; Wang, L. openurl 
  Title (up) A Preliminary Comparision of the Analgesic Time-Effect Regularity Between Single-Acupoint and Multi-Acupoint Acupuncture in Primary Dysmenorrhea Patients Type of Study RCT
  Year 2010 Publication International Journal of Clinical Acupuncture Abbreviated Journal Int J Clin Acupunct  
  Volume 19 Issue 3 Pages 97-99  
  Keywords AcuTrials; RCT; Menstruation Disturbances; Dysmenorrhea; Acu Versus CAM Control; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; CAM Control; Acu Versus Acu  
  Abstract  
  Address  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up N/A Frequency N/A Number of Participants 20  
  Time in Treatment 1 Day Condition Dysmennorhea
  Disease Category Menstruation Disturbances OCSI Score  
  Notes Approved no  
  Call Number Serial 146  
Permanent link to this record
 

 
Author Kwong, E. Y.; Yiu, E. M. url  openurl
  Title (up) A preliminary study of the effect of acupuncture on emotional stress in female dysphonic speakers Type of Study RCT
  Year 2010 Publication Journal of voice : official journal of the Voice Foundation Abbreviated Journal J Voice  
  Volume 24 Issue 6 Pages 719-723  
  Keywords Mental Disorders; Stress, Psychological; RCT; AcuTrials; Pilot Study; Acu Versus Sham; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Sham Control; Non Penetrating Sham, Mechanical; Verum Acupoint Control; Dysphonia; Voice Disorders  
  Abstract This study investigated the effect of acupuncture on emotional stress in subjects with phonotraumatic injuries. This study used a prospective randomized, placebo-controlled group design. The independent variable included the types of acupuncture (genuine vs sham) and the sampling time points (two pre-needling, one in the midway of needling, and two post-needling measurements). The dependent variable was the concentration of cortisol obtained from subjects' saliva samples. Eighteen female subjects with phonotraumatic injuries were randomized to receive either genuine or sham acupuncture at the same acupoints during a 30-minute session. Saliva samples were collected from each subject at 10 minutes pre-needling, immediately pre-needling, mid-needling, immediately postneedling, and 10 minutes post-needling time points. The findings suggested that the subjects' salivary cortisol concentration did not reduce after acupuncture, and thus, acupuncture may not be able to reduce the emotional stress level in female dysphonic speakers.  
  Address Division of Speech &amp; Hearing Sciences, Voice Research Laboratory, The University of Hong Kong, Sai Ying Pun, Hong Kong. jasperek@graduate.hku.uk  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up N/A Frequency N/A Number of Participants 18  
  Time in Treatment 1 Day Condition Stress, Psychological
  Disease Category Mental Disorders OCSI Score  
  Notes Approved no  
  Call Number Serial 614  
Permanent link to this record
 

 
Author Itoh, K.; Okada, K.; Kawakita, K. openurl 
  Title (up) A proposed experimental model of myofascial trigger points in human muscle after slow eccentric exercise Type of Study Journal Article
  Year 2004 Publication Acupuncture in medicine : journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 22 Issue 1 Pages 2-12; discussion 12-3  
  Keywords Nrct; Healthy Subjects  
  Abstract BACKGROUND: The purpose of this study was to develop an experimental model of myofascial trigger points to investigate their pathophysiology. METHODS: Fifteen healthy volunteers who gave informed consent underwent repetitive eccentric exercise of the third finger of one hand (0.1 Hz repetitions, three sets at five minute intervals) until exhaustion. Physical examination, pressure pain threshold, and electrical pain threshold of the skin, fascia and muscle were measured immediately afterwards and for seven days. Needle electromyogram (EMG) was also recorded in a subgroup of participants. RESULTS: Pressure pain thresholds decreased to a minimum on the second day after the exercise, then gradually returned to baseline values by the seventh day. On the second day, a ropy band was palpated in the exercised forearm muscle and the electrical pain threshold of the fascia at the palpable band was the lowest among the measured loci and tissues. Needle EMG activity accompanied with dull pain sensation was recorded only when the electrode was located on or near the fascia of the palpable band on the second day of exercise. CONCLUSION: These results suggest that eccentric exercise may yield a useful model for the investigation of the myofascial trigger points and/or acupuncture points. The sensitised nociceptors at the fascia of the palpable band might be a possible candidate for the localised tender region.  
  Address Meiji University of Oriental Medicine, Kyoto, Japan.  
  Publisher
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category Healthy Subjects OCSI Score  
  Notes Date of Input: 9/29/2015; Date Modified: 9/29/2015; Availability: --In File--; Priority: Normal; Meiji University of Oriental Medicine, Kyoto, Japan.; eng; Web: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15077932 Approved no  
  Call Number OCOM @ refbase @ Serial 1816  
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Author Tong, F. M.; Chow, S. K.; Chan, P. Y.; Wong, A. K.; Wan, S. S.; Ng, R. K.; Chan, G.; Chan, W. S.; Ng, A.; Law, C. K. url  openurl
  Title (up) A prospective randomised controlled study on efficacies of acupuncture and steroid in treatment of idiopathic peripheral facial paralysis Type of Study RCT
  Year 2009 Publication Acupuncture in medicine : journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 27 Issue 4 Pages 169-173  
  Keywords AcuTrials; RCT; Cranial Nerve Diseases; Bell Palsy; Facial Paralysis; Acu Versus > 1 Control; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Usual Care Control, Pharmaceutical; Usual Care Control, Educational  
  Abstract OBJECTIVE: A randomised controlled trial was undertaken to evaluate the efficacy of acupuncture in comparison with steroid in treatment of idiopathic peripheral facial paralysis (Bell's palsy). METHODS: A total of 119 patients attending Ear, Nose and Throat Clinic of Pamela Youde Nethersole Eastern Hospital from February 2003 to December 2005 were randomly allocated to groups of acupuncture, steroid and control (conventional expectant treatment). There were 53 in the steroid group, 28 in the acupuncture group and 38 in the control group. Patients were assessed weekly by blinded assessors, using the House-Brackmann facial nerve grading system. RESULTS: The efficacy of treatment in three groups was compared, in terms of degree of recovery and speed of recovery. Intention-to-treat analyses were performed. Results were analysed with SPSS software. Distribution of initial grade on presentation was analysed with the Pearson chi-square test and showed uneven distribution in the three groups in the intention-to-treat analysis. The overall improvement (grade 3 or better) was 86.9% in the steroid group, 96.4% in the acupuncture group and 89.5% in the control group respectively. However, the difference in degree of recovery and speed of recovery in the three groups was not statistically significant. CONCLUSION: The efficacies of acupuncture, steroid and conventional expectant treatment (natural course of recovery) in idiopathic peripheral facial palsy (Bell's palsy) in the study were the same with respect to the degree of recovery and speed of recovery.  
  Address Department of ENT, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, PR China; tongfm@yahoo.com.  
  Publisher
  Language Number of Treatments 18  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants 119  
  Time in Treatment 6 Weeks Condition Bell Palsy
  Disease Category Cranial Nerve Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 1169  
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Author Dieterle, S.; Li, C.; Greb, R.; Bartzsch, F.; Hatzmann, W.; Huang, D. url  openurl
  Title (up) A prospective randomized placebo-controlled study of the effect of acupuncture in infertile patients with severe oligoasthenozoospermia Type of Study RCT
  Year 2009 Publication Abbreviated Journal Fertil Steril  
  Volume Issue Pages -  
  Keywords Infertility, Male; Oligoasthenozoospermia; RCT; Sperm Concentration; Sperm Morphology; Sperm Motility; Sperm Quality; Genital Diseases, Male; Acu Versus Sham; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; Sham Control; Non Penetrating Sham, Mechanical; Verum Acupoint Control; AcuTrials  
  Abstract In this first prospective, randomized, single-blind, placebo-controlled study, 28 infertile patients with severe oligoasthenozoospermia received acupuncture according to the principles of traditional Chinese medicine (TCM) and 29 infertile patients received placebo acupuncture. A significantly higher percentage of motile sperm (World Health Organization categories A-C), but no effect on sperm concentration, was found after acupuncture compared with placebo acupuncture  
  Address Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Witten/Herdecke, Dortmund, Germany; Infertility Center Dortmund, Dortmund, Germany  
  Publisher
  Language Number of Treatments 12  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants 28  
  Time in Treatment 6 Weeks Condition Infertility, Male
  Disease Category Genital Diseases, Male OCSI Score  
  Notes Approved no  
  Call Number Serial 246  
Permanent link to this record
 

 
Author Wedenberg, K.; Moen, B.; Norling, A. url  openurl
  Title (up) A prospective randomized study comparing acupuncture with physiotherapy for low-back and pelvic pain in pregnancy Type of Study RCT
  Year 2000 Publication Acta obstetricia et gynecologica Scandinavica Abbreviated Journal Acta Obstet Gynecol Scand  
  Volume 79 Issue 5 Pages 331-335  
  Keywords Acu Versus Usual Care; Acupuncture; AcuTrials; Auricular Acupuncture; Low Back Pain; Pain; Pelvic Pain; Physical Therapy; RCT; Restricted Modalities, Acupuncture Only; Semi-Individualized Acupuncture Protocol; Usual Care Control, Physical; Traditional Diagnosis Based Point Selection; Women's Health; Pregnancy Complications  
  Abstract BACKGROUND: The aim of this study was to describe the effects of acupuncture in the treatment of low-back and pelvic pain during pregnancy and compare it with physiotherapy. METHODS: Sixty pregnant women were allotted to acupuncture or physiotherapy. The women estimated the severity of their pain using a visual analog scale (VAS) from 0 to 10 and disability in performing twelve common daily activities using a disability-rating index (DRI) from 0 to 10. RESULTS: In the acupuncture group all 30 women completed the study (two exclusions), in the physiotherapy group only 18. Before treatment the two study groups were rather similar with respect to pain and disability. After treatment the mean morning VAS had declined from 3.4 to 0.9 (p<0.01) in the acupuncture group and from 3.7 to 2.3 (NS) in the physiotherapy group. The corresponding evening values had declined from 7.4 to 1.7 (p<0.01) and 6.6 to 4.5 (p<0.01), respectively. The mean VAS values were lower after acupuncture than after physiotherapy both in the morning (p=0.02) and in the evening (p<0.01). After treatment also the mean DRI values had decreased significantly in the acupuncture group for 11 of 12 activities and the values were significantly lower for all activities than in the physiotherapy group where no significant changes had taken place. Overall satisfaction was good in both groups. There were no serious adverse events in any of the patients. CONCLUSIONS: Acupuncture relieved pain and diminished disability in low-back pain during pregnancy better than physiotherapy  
  Address Department of Obstetrics and Gynecology, Vrinnevi Hospital, Norrkoping, Sweden  
  Publisher
  Language Number of Treatments 10  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants 60  
  Time in Treatment 4 Weeks Condition Pelvic Pain
  Disease Category Pregnancy Complications OCSI Score 56  
  Notes Approved no  
  Call Number Serial 1279  
Permanent link to this record
 

 
Author Stener-Victorin, E.; Waldenstrom, U.; Nilsson, L.; Wikland, M.; Janson, P. O. url  openurl
  Title (up) A prospective randomized study of electro-acupuncture versus alfentanil as anaesthesia during oocyte aspiration in in-vitro fertilization Type of Study RCT
  Year 1999 Publication Abbreviated Journal Hum Reprod  
  Volume 14 Issue 10 Pages 2480-2484  
  Keywords Abdominal Pain; Acu Versus Usual Care; Acupuncture; AcuTrials; Anesthesia and Analgesia; Aspiration; Electroacupuncture; Embryo Transfer; Fixed Acupuncture Protocol; In Vitro Fertilization; Nausea; Pain; Pregnancy Rate; RCT; Restricted Modalities, Acupuncture Only; Stress, Psychological; Women's Health; Usual Care Control, Pharmaceutical; Reproductive Techniques, Assisted; IVF; Fertilization In Vitro  
  Abstract The aim of the present study was to evaluate the anaesthetic effect during oocyte aspiration of a paracervical block (PCB) in combination with either electro-acupuncture (EA) or intravenous alfentanil. In all, 150 women undergoing in-vitro fertilization (IVF) and embryo transfer were randomized to receive either EA plus PCB or alfentanil plus PCB. Visual analogue scales (VAS) were used to evaluate subjective experiences during oocyte aspiration, and IVF outcome parameters were recorded. No differences in pain directly related to oocyte aspiration, adequacy of anaesthesia during oocyte aspiration, abdominal pain, or degree of nausea were found between the two groups in the VAS ratings. Before oocyte aspiration, the level of stress was significantly higher in the EA group than in the alfentanil group (P < 0.05), and the EA group experienced discomfort for a significantly longer period during oocyte aspiration (P < 0. 01). Compared with the alfentanil group, the EA group had a significantly higher implantation rate (P < 0.05), pregnancy rate (P < 0.05), and take home baby rate (P < 0.05) per embryo transfer. In conclusion, EA has been shown to be as good an anaesthetic method as alfentanil during oocyte aspiration, and we suggest that EA may be a good alternative to conventional anaesthesia during oocyte aspiration  
  Address Department of Obstetrics and Gynaecology, Goteborg University, SE-413 45 Goteborg, Sweden  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up N/A Frequency N/A Number of Participants 150  
  Time in Treatment 1 Day Condition Fertilization In Vitro
  Disease Category Reproductive Techniques, Assisted OCSI Score 58  
  Notes Approved no  
  Call Number Serial 1109  
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Author Johnstone, P. A.; Bloom, T. L.; Niemtzow, R. C.; Crain, D.; Riffenburgh, R. H.; Amling, C. L. url  openurl
  Title (up) A Prospective, Randomized Pilot Trial of Acupuncture of the Kidney-Bladder Distinct Meridian for Lower Urinary Tract Symptoms Type of Study RCT
  Year 2003 Publication The Journal of urology Abbreviated Journal J Urol  
  Volume 169 Issue 3 Pages 1037-1039  
  Keywords Acu Versus > 1 Control; Acupuncture; AcuTrials; Electroacupuncture; Fixed Acupuncture Protocol; Penetrating Sham; Genital Diseases, Male; No Treatment Control; RCT; Restricted Modalities, Acupuncture Only; Sham Acupoint Control; Sham Control; TCM Acupuncture Style; Urinary Tract Infection; Urination Disorders; Urologic Diseases; Wait-List Control; Standard Needling Depth  
  Abstract PURPOSE We performed a pilot trial to assess the response of lower urinary tract symptoms and prostate specific antigen (PSA) to acupuncture in a population of patients biopsy negative for prostate cancer.MATERIALS AND METHODS A total of 30 patients were randomly assigned to 1 of 3 study groups, including observation for 3 months with 6 blood samples for PSA at set intervals, 9 sessions of acupuncture in 3 months to points of the kidney-bladder distinct meridian expected to treat the prostate with 6 blood samples for PSA at set intervals and 9 sessions of acupuncture in 3 months to points not expected to treat the prostate with 6 blood samples for PSA at set intervals. The effect of acupuncture on lower urinary tract symptoms was assessed monthly using the International Prostate Symptom Score.RESULTS Trend analysis (repeated measures ANOVA) revealed no significant changes in the 3-month period in the randomized arms. Statistical analysis showed p = 0.063 for the International Prostate Symptom Score, p = 0.945 for PSA and p = 0.37 for the free-to-total PSA ratio.CONCLUSIONS Acupuncture to the kidney-bladder distinct meridian neither relieves lower urinary tract symptoms nor impacts PSA  
  Address  
  Publisher
  Language Number of Treatments 9  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants 30  
  Time in Treatment 12 Weeks Condition Urinary Tract Infection
  Disease Category Urologic Diseases OCSI Score 60  
  Notes Approved no  
  Call Number Serial 537  
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Author Garvey, T. A.; Marks, M. R.; Wiesel, S. W. url  openurl
  Title (up) A prospective, randomized, double-blind evaluation of trigger-point injection therapy for low-back pain Type of Study RCT
  Year 1989 Publication Spine Abbreviated Journal Spine (Phila Pa 1976)  
  Volume 14 Issue 9 Pages 962-964  
  Keywords RCT; AcuTrials; Back Pain; Low Back Pain, Acute; Acu Versus > 1 Control; Acupuncture; Acupressure; Trigger Point Acupuncture Style; Symptom Based Point Selection; Restricted Modalities, Acupuncture Only; Usual Care Control, Pharmaceutical; Pain; CAM Control; Individualized Acupuncture Protocol  
  Abstract The efficacy of trigger-point injection therapy in treatment of low-back strain was evaluated in a prospective, randomized, double-blind study. The patient population consisted of 63 individuals with low-back strain. Patients with this diagnosis had nonradiating low-back pain, normal neurologic examination, absence of tension signs, and lumbosacral roentgenograms interpreted as being within normal limits. They were treated conservatively for 4 weeks before entering the study. Injection therapy was of four different types: lidocaine, lidocaine combined with a steroid, acupuncture, and vapocoolant spray with acupressure. Results indicated that therapy without injected medication (63% improvement rate) was at least as effective as therapy with drug injection (42% improvement rate), at a P value of 0.09. Trigger-point therapy seems to be a useful adjunct in treatment of low-back strain. The injected substance apparently is not the critical factor, since direct mechanical stimulus to the trigger-point seems to give symptomatic relief equal to that of treatment with various types of injected medication.  
  Address Department of Orthopaedic Surgery, George Washington University Medical Center, Washington, D.C.  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up 2 Weeks Frequency N/A Number of Participants 63  
  Time in Treatment 1 Day Condition Low Back Pain, Acute
  Disease Category Back Pain OCSI Score  
  Notes Approved no  
  Call Number Serial 365  
Permanent link to this record
 

 
Author Ning Wang; Sheng-Feng Lu; Hui Chen; Jian-Fei Wang; Shu-Ping Fu; Chen-Jun Hu; Yi Yang; Fan-Rong Liang; Bing-Mei Zhu url  doi
openurl 
  Title (up) A protocol of histone modification-based mechanistic study of acupuncture in patients with stable angina pectoris Type of Study Journal Article
  Year 2015 Publication BMC Complementary & Alternative Medicine Abbreviated Journal Bmc Complement Altern Med  
  Volume 15 Issue 1 Pages 1-11  
  Keywords Electroacupuncture; Angina, Stable -- Therapy; Proteins -- Metabolism; Protocols; Human; Randomized Controlled Trials; Double-Blind Studies; Random Assignment; Patient Selection; Adult; Middle Age; Aged; Aged, 80 and Over; Male; Female; Polymerase Chain Reaction; Descriptive Statistics; Kruskal-Wallis Test; Chi Square Test; Paired T-Tests; Wilcoxon Signed Rank Test; Confidence Intervals; Scales; Fisher's Exact Test; Correlation Coefficient; China; Funding Source  
  Abstract Background: Angina pectoris (Angina) is a medical condition related to myocardial ischemia. Although acupuncture has been widely accepted as a clinical approach for angina, there is no sufficient evidence of its effectiveness against this syndrome, and its mechanisms have not yet been well elucidated. We develop this protocol to confirm the clinical efficacy of electro-acupuncture on stable angina pectoris by needling on acupoint Neiguan (PC6). Furthermore, we employ high-throughput sequencing technology to investigate the gene expression profiling and determine involvement of histone modifications in the regulation of genes after electro-acupuncture treatment. Methods/Design: A randomized, controlled, double-blinded (assessor and patients) trial will be carried out. Sixty participants will be randomly assigned to two acupuncture treatment groups and one control group in a 1:1:1 ratio. Participants in acupuncture groups will receive 12 sessions of electro-acupuncture treatment across 4 weeks, followed by a 12-week randomization period. The acupuncture groups are divided into Neiguan (PC6) on Pericardium Meridian of Hand-jueyin or a non-acupoint. The primary clinical measure of effect is the frequency of angina attacks between these groups for four weeks after randomization. RNAs are extracted from peripheral neutrophils collected from all participants on day 0, day 30, and week 16, and are processed to RNA-Seq. We then investigate profiles of histone modifications by ChIP-Seq, for H3 Lysine 4 (H3K4me) and acetylation of H3 Lysine 27 (H3K27ac), in the presence or absence of acupuncture treatment. Discussion: This study determines the efficacy and mechanisms of electro-acupuncture on stable angina pectoris. We focus on effectiveness of acupuncture on alleviating symptoms of myocardial ischemia and the gene regulation and the chromatin remodeling marks, including H3K4me1, H3K4me2, and H3K27ac, which could be key factors for regulating gene expressions caused by electro-acupuncture treatment at Neiguan. This is the first genome-wide study of electro-acupuncture treatment in angina patients, and will provide valuable information for future studies in the fields of acupuncture and its underlying mechanisms. Fourteen patients have been recruited since recruitment opened in November of 2012. This study is scheduled to end in November of 2014.  
  Address School of Acupuncture and Tuina, Chengdu University of Traditiona Chinese Medicine, 610075 Chengdu, Sichuan, China  
  Publisher BioMed Central
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 109830838. Language: English. Entry Date: 20150721. Revision Date: 20150923. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Instrumentation: Self-Rating Depression Scale (SDS); Self-rating Anxiety Scale (SAS). Grant Information: The trial is sponsored and financially supported by (973 Program, No. 2012CB518501) the Ministry of Science and Technology of China.. NLM UID: 101088661. Approved no  
  Call Number OCOM @ refbase @ 109830838 Serial 2305  
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Author Jakes, D.; Kirk, R.; Muir, L. url  doi
openurl 
  Title (up) A Qualitative Systematic Review of Patients' Experiences of Acupuncture Type of Study Journal Article
  Year 2014 Publication Journal of Alternative & Complementary Medicine Abbreviated Journal J Altern Complement Med  
  Volume 20 Issue 9 Pages 663-671  
  Keywords Acupuncture; Patient Attitudes; Health Beliefs; Human; New Zealand; Professional Practice, Evidence-Based; Systematic Review; Qualitative Studies -- Evaluation; Alternative Therapies; CINAHL Database; PubMed; Medline; Psycinfo; Quantitative Studies -- Evaluation; Research Methodology -- Evaluation; Study Design -- Evaluation; Scales; Thematic Analysis; Decision Making, Patient; Treatment Outcomes; Descriptive Statistics; Validity; Patient Satisfaction; Educational Status; Diagnosis -- Methods; Health Care Delivery; Communication; Professional-Patient Relations; Sensation; Quality of Life  
  Abstract Objectives: To present the results of a systematic review of studies on acupuncture patients' health beliefs and treatment experiences. Search strategy: The search was conducted using CINAHL, PubMed, Ovid MEDLINE, ISI Web of Science, and PsychINFO for qualitative and mixed-methods studies expressing the voice of acupuncture patients. Reference lists of relevant articles were also searched. The review was restricted to studies published in English. Data collection and analysis: Study selection, quality appraisal, and data extraction were performed sequentially. Quality was appraised using the Joanna Briggs Institute Qualitative Assessment and Review Instrument, and the Dedoose mixed methods tool was used in data management and analysis. Results: Four overarching themes were identified: reasons for using acupuncture, treatment experiences, treatment outcomes, and therapeutic model. Conclusions: Patients' reasons for using acupuncture are diverse and include dissatisfaction with conventional medicine and attraction to holistic and empowering models of healthcare. Treatment is thought to relieve symptoms of the presenting concern and a range of other effects that improve well-being. This review highlights the need to improve understanding of patients' health-seeking behaviors and how individually meaningful treatment outcomes may be understood and assessed, particularly within complementary and alternative medicine.  
  Address  
  Publisher Mary Ann Liebert, Inc.
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 103889722. Language: English. Entry Date: 20140909. Revision Date: 20150901. Publication Type: Journal Article; research; systematic review; tables/charts. Journal Subset: Alternative/Complementary Therapies; Editorial Board Reviewed; Expert Peer Reviewed; Peer Reviewed; USA. Special Interest: Evidence-Based Practice. Instrumentation: Joanna Briggs Institute Qualitative Assessment and Review Instrument. NLM UID: 9508124. Approved no  
  Call Number OCOM @ refbase @ 103889722 Serial 2348  
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Author Ratcliffe, J.; Thomas, K. J.; MacPherson, H.; Brazier, J. url  openurl
  Title (up) A randomised controlled trial of acupuncture care for persistent low back pain: cost effectiveness analysis Type of Study RCT
  Year 2006 Publication Abbreviated Journal BMJ  
  Volume 333 Issue 7569 Pages 626-  
  Keywords Acu + Usual Care Versus Usual Care; Acupuncture; AcuTrials; Back Pain; Low Back Pain, Chronic; Cost Effectiveness; Individualized Acupuncture Protocol; Low Back Pain; Pain; RCT; Restricted Modalities, Acupuncture Only; Usual Care Control, Unspecified; TCM Acupuncture Style; Traditional Diagnosis Based Point Selection; Back Pain  
  Abstract OBJECTIVE: To evaluate the cost effectiveness of acupuncture in the management of persistent non-specific low back pain. DESIGN: Cost effectiveness analysis of a randomised controlled trial. SETTING: Three private acupuncture clinics and 18 general practices in York, England. PARTICIPANTS: 241 adults aged 18-65 with non-specific low back pain of 4-52 weeks' duration. INTERVENTIONS: Ten individualised acupuncture treatments over three months from acupuncturists trained in traditional Chinese medicine (n = 160) or usual care only (n = 81). MAIN OUTCOME MEASURE: Incremental cost per quality adjusted life year (QALY) gained over two years. RESULTS: Total costs to the United Kingdom's health service during the two year study period were higher on average for the acupuncture group (460 pounds sterling; 673 euros; 859 dollars) than for the usual care group (345 pounds sterling) because of the costs associated with initial treatment. The mean incremental health gain from acupuncture at 12 months was 0.012 QALYs (95% confidence interval -0.033 to 0.058) and at 24 months was 0.027 QALYs (-0.056 to 0.110), leading to a base case estimate of 4241 pounds sterling per QALY gained. This result was robust to sensitivity analysis. The probabilistic sensitivity analysis showed acupuncture to have a more than 90% chance of being cost effective at a pound20 000 cost per QALY threshold. CONCLUSION: A short course of traditional acupuncture for persistent non-specific low back pain in primary care confers a modest health benefit for minor extra cost to the NHS compared with usual care. Acupuncture care for low back pain seems to be cost effective in the longer term. TRIAL REGISTRATION: ISRCTN80764175 [controlled-trials.com]  
  Address School of Health and Related Research, University of Sheffield. j.ratcliffe@sheffield.ac.uk  
  Publisher
  Language Number of Treatments 10  
  Treatment Follow-up 104 Weeks Frequency <1/WK Number of Participants 241  
  Time in Treatment 12 Weeks Condition Low Back Pain, Chronic
  Disease Category Back Pain OCSI Score  
  Notes Approved no  
  Call Number Serial 975  
Permanent link to this record
 

 
Author Fogarty, S.; Stojanovska, L.; Harris, D.; Zaslawski, C.; Mathai, M.L.; McAinch, A.J. url  doi
openurl 
  Title (up) A randomised cross-over pilot study investigating the use of acupuncture to promote weight loss and mental health in overweight and obese individuals participating in a weight loss program Type of Study Journal Article
  Year 2015 Publication Eating & Weight Disorders Abbreviated Journal Eat Weight Disord  
  Volume 20 Issue 3 Pages 379-387  
  Keywords  
  Abstract Background: Acupuncture is widely used as an alternative modality for weight loss. Despite its increasing use, few acupuncture studies have evaluated the effect of a weight loss program on the mental health of obese/overweight participants and none have looked at the effect on those with eating, weight and shape concerns.Objectives: To investigate the feasibility of conducting an acupuncture study involving overweight or obese individuals undertaking a weight loss program with particular reference to those with eating concerns.Methods: Thirty-five overweight/obese males and females participated in a single-blinded randomised cross-over study. The two intervention phases were: (1) nutritional counselling plus Traditional Chinese Medicine (TCM) acupuncture and (2) nutritional counselling plus sham acupuncture.Outcome Measures: This study evaluates the feasibility and practicalities of the study including recruitment, retention, adverse events, effectiveness for defining eating and weight concerns, study design and statistics for power calculations.Conclusion: The outcome measures, the recruitment of those with eating and weight concerns and the acceptability of the intervention demonstrate a larger trial investigating the use of acupuncture for weight loss in those who have elevated eating and weight concerns is feasible.  
  Address  
  Publisher Springer Science & Business Media B.V.
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 109638538. Language: English. Entry Date: 20150923. Revision Date: 20160603. Publication Type: journal article; research; randomized controlled trial. Journal Subset: Biomedical; Blind Peer Reviewed; Continental Europe; Editorial Board Reviewed; Europe; Expert Peer Reviewed; Peer Reviewed. Special Interest: Nutrition. NLM UID: 9707113. Approved no  
  Call Number OCOM @ refbase @ 109638538 Serial 2306  
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Author Ortiz, M.; Witt, C.M.; Binting, S.; Helmreich, C.; Hummelsberger, J.; Pfab, F.; Wullinger, M.; Irnich, D.; Linde, K.; Niggemann, B.; Willich, S.N.; Brinkhaus, B. url  doi
openurl 
  Title (up) A randomised multicentre trial of acupuncture in patients with seasonal allergic rhinitis – trial intervention including physician and treatment characteristics Type of Study Journal Article
  Year 2014 Publication BMC Complementary & Alternative Medicine Abbreviated Journal Bmc Complement Altern Med  
  Volume 14 Issue 1 Pages 1-19  
  Keywords Rhinitis, Allergic, Seasonal -- Prevention and Control; Acupuncture -- Utilization; Human; Multicenter Studies; Randomized Controlled Trials; Questionnaires; Descriptive Statistics; Female; Male; Middle Age; Adult; Medicine, Chinese Traditional; Data Analysis Software; Acupuncture Points; Physicians; Funding Source  
  Abstract  
  Address Department of Pediatrics, Division of Pneumonology and Immunology, Charité-Universitätsmedizin, Berlin, Germany  
  Publisher BioMed Central
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 103934197. Language: English. Entry Date: 20140423. Revision Date: 20150710. Publication Type: Journal Article; research; tables/charts; randomized controlled trial. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Expert Peer Reviewed; Peer Reviewed; UK & Ireland. Grant Information: This study was funded by a grant from the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) Grant No. WI 957/16-1.. NLM UID: 101088661. Approved no  
  Call Number OCOM @ refbase @ 103934197 Serial 2384  
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Author Mao, J. J.; Xie, S. X.; Farrar, J. T.; Stricker, C. T.; Bowman, M. A.; Bruner, D.; DeMichele, A. url  doi
openurl 
  Title (up) A randomised trial of electro-acupuncture for arthralgia related to aromatase inhibitor use Type of Study RCT
  Year 2014 Publication European journal of cancer (Oxford, England : 1990) Abbreviated Journal Eur J Cancer  
  Volume 50 Issue 2 Pages 267-276  
  Keywords Neoplasms; Breast Neoplasms; Chemotherapy Side Effects; Pain; Arthralgia; Musculoskeletal Diseases; RCT; Acu Versus > 1 Control; Electroacupuncture; TCM Acupuncture Style; Semi-Individualized Acupuncture Protocol; Symptom Based Point Selection; Wait List Control; Sham Control; Non Penetrating Sham, Electrical; Sham Acupoint Control; Manualized Acupuncture Protocol; Manualized Acupuncture Protocol  
  Abstract BACKGROUND: Arthralgia is a common and debilitating side-effect experienced by breast cancer patients receiving aromatase inhibitors (AIs) and often results in premature drug discontinuation. METHODS: We conducted a randomised controlled trial of electro-acupuncture (EA) as compared to waitlist control (WLC) and sham acupuncture (SA) in postmenopausal women with breast cancer who self-reported arthralgia attributable to AIs. Acupuncturists performed 10 EA/SA treatments over 8 weeks using a manualised protocol with 2 Hz electro-stimulation delivered by a TENS unit. Acupuncturists administered SA using Streitberger (non-penetrating) needles at non-traditional acupuncture points without electro-stimulation. The primary end-point was pain severity by Brief Pain Inventory (BPI) between EA and WLC at Week 8; durability of response at Week 12 and comparison of EA to SA were secondary aims. FINDINGS: Of the 67 randomly assigned patients, mean reduction in pain severity was greater in the EA group than in the WLC group at Week 8 (-2.2 versus -0.2, p=0.0004) and at Week 12 (-2.4 versus -0.2, p<0.0001). Pain-related interference measured by BPI also improved in the EA group compared to the WLC group at both Week 8 (-2.0 versus 0.2, p=0.0006) and Week 12 (-2.1 versus -0.1, p=0.0034). SA produced a magnitude of change in pain severity and pain-related interference at Week 8 (-2.3, -1.5 respectively) and Week 12 (-1.7, -1.3 respectively) similar to that of EA. Participants in both EA and SA groups reported few minor adverse events. INTERPRETATIONS: Compared to usual care, EA produced clinically important and durable improvement in arthralgia related to AIs in breast cancer patients, and SA had a similar effect. Both EA and SA were safe.  
  Address Department of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, PA, United States; Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, Perelman School  
  Publisher
  Language Number of Treatments 10  
  Treatment Follow-up 12 Weeks Frequency >1/WK Number of Participants 67  
  Time in Treatment 8 Weeks Condition Arthralgia
  Disease Category Pain OCSI Score  
  Notes Approved no  
  Call Number Serial 824  
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Author Wang, K.; Bugge, J.; Bugge, S. url  openurl
  Title (up) A randomised, placebo-controlled trial of manual and electrical acupuncture for the treatment of tinnitus Type of Study RCT
  Year 2010 Publication Complementary therapies in medicine Abbreviated Journal Complement Ther Med  
  Volume 18 Issue 6 Pages 249-255  
  Keywords AcuTrials; Ear Diseases; Tinnitus; RCT; Acu Versus > 1 Control; Acupuncture; Electroacupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities, Acupuncture Only; CAM Control; Acu Versus Acu; Sham Control; Non Penetrating Sham, Mechanical; Verum Acupoint Control  
  Abstract The aim of this study was to examine the effects of manual/electrical acupuncture treatment on tinnitus in a randomised, single-blinded, placebo-controlled design. Fifty patients (46 males, 4 females) suffering from tinnitus were investigated. The patients were randomly assigned to three groups: a manual acupuncture group (MA), an electrical acupuncture group (EA), and a placebo group (PL). The frequency of tinnitus occurrence, tinnitus intensity, and reduction of life quality were recorded before treatment (Baseline), after 6 treatments (After-Treatment), and 1 month after the completion of treatment (1-Month-After). Standard audiometric tests were conducted on each patient at Baseline and After-Treatment. The patients also provided an overall subjective evaluation of treatment effectiveness at each stage. Eight to ten acupoints were selected at each treatment by an experienced acupuncturist. Six treatments were performed, each separated by an interval of 1 week. Analysis of variance and t-tests were used to statistically compare the data. The frequency of tinnitus occurrence and the tinnitus loudness were significantly decreased After-Treatment compared with Baseline in the EA group (P<0.009). Life quality was improved After-Treatment and at 1-Month-After compared with Baseline in both MA and EA groups (P<0.038). However, no significant differences were detected among the three groups (P>0.079). The audiogram did not show any significant changes after treatment in either group (P>0.091). The overall subjective evaluation indicated significant improvements After-Treatment compared with Baseline in both MA and EA groups (P<0.011). Furthermore, After-Treatment subjective evaluation was significantly better in the EA group compared with either the MA or PL group (P<0.011). These results indicate that there is no statistically significant differential effect of manual or electrical acupuncture on tinnitus treatment efficacy, however, electrical acupuncture does confer some relative advantages.  
  Address Center for Sensory-Motor Interaction, Orofacial Pain Laboratory, Aalborg University, Fredrik Bajers Vej 7 D-3, DK-9220 Aalborg, Denmark. kelun@smi.auc.dk  
  Publisher
  Language Number of Treatments 6  
  Treatment Follow-up 4 Weeks Frequency 1/WK Number of Participants 50  
  Time in Treatment 6 Weeks Condition Tinnitus
  Disease Category Ear Diseases OCSI Score  
  Notes Approved no  
  Call Number Serial 1246  
Permanent link to this record
 

 
Author Kvist, L. J.; Louise Hall-Lord, M.; Rydhstroem, H.; Wilde, Larsson B. url  openurl
  Title (up) A randomised-controlled trial in Sweden of acupuncture and care interventions for the relief of inflammatory symptoms of the breast during lactation Type of Study RCT
  Year 2006 Publication Abbreviated Journal Midwifery  
  Volume Issue Pages -  
  Keywords CAM Control; Acu + Usual Care Versus > 1 Control; Acupuncture; AcuTrials; Fixed Acupuncture Protocol; Pain; RCT; Restricted Modalities, Acupuncture Only; Usual Care Control, Multimodality; Unspecified Acupuncture Style; Women's Health; Pregnancy Complications  
  Abstract OBJECTIVES: to further compare acupuncture treatment and care interventions for the relief of inflammatory symptoms of the breast during lactation and to investigate the relationship between bacteria in the breast milk and clinical signs and symptoms. DESIGN: randomised, non-blinded, controlled trial of acupuncture and care interventions. SETTING: a midwife-led breast feeding clinic in Sweden. PARTICIPANTS: 205 mothers with 210 cases of inflammatory symptoms of the breast during lactation agreed to participate. The mothers were randomly assigned to one of three treatment groups, two of which included acupuncture among the care interventions and one without acupuncture. All groups were given essential care. Protocols, which included scales for erythema, breast tension and pain, were maintained for each day of contact with the breast feeding clinic. A Severity Index (SI) for each mother and each day was created by adding together the scores on the erythema, breast tension and pain scales. The range of the SI was 0 (least severe) to 19 (most severe). FINDINGS: no significant difference was found in numbers of mothers in the treatment groups, with the lowest possible score for severity of symptoms on contact days 3, 4 or 5. No statistically significant differences were found between the treatment groups for number of contact days needed until the mother felt well enough to discontinue contact with the breast feeding clinic or for number of mothers prescribed antibiotics. Significant differences were found in the mean SI scores on contact days 3 and 4 between the non-acupuncture group and the two acupuncture groups. Mothers with less favourable outcomes (6 contact days, n=61) were, at first contact with the midwife, more often given advice on correction of the baby's attachment to the breast. An obstetrician was called to examine 20% of the mothers, and antibiotic treatment was prescribed for 15% of the study population. The presence of Group B streptococci in the breast milk was related to less favourable outcomes. KEY CONCLUSIONS AND IMPLICATIONS FOR PRACTICE: if acupuncture treatment is acceptable to the mother, this, together with care interventions such as correction of breast feeding position and babies' attachment to the breast, might be a more expedient and less invasive choice of treatment than the use of oxytocin nasal spray. Midwives, nurses or medical practitioners with specialist competence in breast feeding should be the primary care providers for mothers with inflammatory symptoms of the breast during lactation. The use of antibiotics for inflammatory symptoms of the breast should be closely monitored in order to help the global community reduce resistance development among bacterial pathogens  
  Address Department of Obstetrics and Gynaecology, Floor 2, Helsingborg Hospital, Helsingborg, SE-251 87 Sweden; Faculty of Social and Life Sciences, Karlstad University, Sweden  
  Publisher
  Language Number of Treatments 1  
  Treatment Follow-up 5 Days Frequency N/A Number of Participants 205  
  Time in Treatment 1 Day Condition Mastitis
  Disease Category Pregnancy Complications OCSI Score  
  Notes Approved no  
  Call Number Serial 607  
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Author Bao, Y. H.; Feng, W.; zhu, G.; Zou, C.; Gong, Y.; Ji, C.; Li, J. openurl 
  Title (up) A Randomized and Comparative Study on Vascular Dementia Treated by Needling Remaining at Head Points Type of Study RCT
  Year 2006 Publication Abbreviated Journal EastWest  
  Volume 4 Issue 1 Pages 12-17  
  Keywords CAM Control; Acu Versus > 1 Control; AcuTrials; Dementia; Electroacupuncture; Fixed Acupuncture Protocol; RCT; RCT; Restricted Modalities, Acupuncture Only; Scalp Acupuncture; Scalp Electroacupuncture; Usual Care Control, Pharmaceutical; TCM Acupuncture Style; Dementia, Vascular  
  Abstract  
  Address  
  Publisher
  Language Number of Treatments 40  
  Treatment Follow-up N/A Frequency >1/WK Number of Participants 60  
  Time in Treatment 8 Weeks Condition Dementia, Vascular
  Disease Category Mental Disorders OCSI Score 54  
  Notes Approved no  
  Call Number Serial 62  
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