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Author Tong Lin; Lan Gong; Xiaoxu Liu; Xiaopeng Ma
Title (up) Fourier-Domain Optical Coherence Tomography for Monitoring the Lower Tear Meniscus in Dry Eye after Acupuncture Treatment Type of Study RCT
Year 2015 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evid Based Complement Altern Med
Volume 2015 Issue Pages 1-10
Keywords AcuTrials; RCT; Eye Diseases; Dry Eye Syndromes; Lipid Tear Deficiency; Sjogren Syndrome; Acu Versus Usual Care; Acupuncture; TCM Acupuncture Style; Fixed Acupuncture Protocol; Restricted Modalities; Acupuncture Only; Usual Care Control; Pharmaceutical
Abstract Dry eye is highly prevalent and has a significant impact on quality of life. Acupuncture was found to be effective to treat dry eye. However, little was known about the effect of acupuncture on different subtypes of dry eye. The objective of this study was to investigate the applicability of tear meniscus assessment by Fourier-domain optical coherence tomography in the evaluation of acupuncture treatment response in dry eye patients and to explore the effect of acupuncture on different subtypes of dry eye compared with artificial tear treatment. A total of 108 dry eye patients were randomized into acupuncture or artificial tear group. Each group was divided into three subgroups including lipid tear deficiency (LTD), Sj¨ogren syndrome dry eye (SSDE), and non-Sj¨ogren syndrome dry eye (Non-SSDE) for data analysis. After 4-week treatment, the low tear meniscus parameters including tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA) in the acupuncture group increased significantly for the LTD and Non-SSDE subgroups compared with both the baseline and the control groups (all P values < 0.05), but not for the SSDE. Acupuncture provided a measurable improvement of the tear meniscus dimensions for the Non-SSDE and LTD patients, but not for the SSDE patients.
Address Department of Ophthalmology, Eye & ENT Hospital of Fudan University, No. 83 Fenyang Road, Shanghai 200031, China
Publisher Hindawi Limited
Language Number of Treatments 12
Treatment Follow-up 6 Weeks Frequency >1/WK Number of Participants 108
Time in Treatment 4 Weeks Condition Dry Eye Syndromes
Disease Category Eye Diseases OCSI Score
Notes Approved no
Call Number OCOM @ refbase @ Serial 2332
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