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Author Liu, H.; Chen, L.; Zhang, Z.; Geng, G.; Chen, W.; Dong, H.; Chen, L.; Zhan, S.; Li, T. url  doi
openurl 
  Title Effectiveness and safety of acupuncture combined with Madopar for Parkinson's disease: a systematic review with meta-analysis Type of Study Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 404-412  
  Keywords Acupuncture Therapy/*mortality; Benserazide/*therapeutic use; Combined Modality Therapy; Dopamine Agents/*therapeutic use; Drug Combinations; Humans; Levodopa/*therapeutic use; Randomized Controlled Trials as Topic; Treatment Outcome; acupuncture; complementary medicine; neurology; parkinson's disease; systematic reviews  
  Abstract OBJECTIVE: To evaluate the effectiveness and safety of acupuncture combined with Madopar for the treatment of Parkinson's disease (PD), compared to the use of Madopar alone. METHODS: A systematic search was carried out for randomised controlled trials (RCTs) of acupuncture and Madopar for the treatment of PD published between April 1995 and April 2015. The primary outcome was total effectiveness rate and secondary outcomes included Unified Parkinson's Disease Rating Scale (UPDRS) scores. Data were pooled and analysed with RevMan 5.3. Results were expressed as relative ratio (RR) with 95% confidence interval (CIs). RESULTS: Finally, 11 RCTs with 831 subjects were included. Meta-analyses showed that acupuncture combined with Madopar for the treatment of PD can significantly improve the clinical effectiveness compared with Madopar alone (RR=1.28, 95% CI 1.18 to 1.38, P<0.001). It was also found that acupuncture combined with Madopar significantly improved the UPDRS II (SMD=-1.00, 95% CI -1.71 to -0.29, P=0.006) and UPDRS I-IV total summed scores (SMD=-1.15, 95% CI -1.63 to -0.67, P<0.001) but not UPDRS I (SMD=-0.37, 95% CI -0.77 to 0.02, P=0.06), UPDRS III (SMD=-0.93, 95% CI -2.28 to 0.41, P=0.17) or UPDRS IV (SMD=-0.78, 95% CI -2.24 to 0.68, P=0.30) scores. Accordingly, acupuncture combined with Madopar appeared to have a positive effect on activities of daily life and the general condition of patients with PD, but was not better than Madopar alone for the treatment of mental activity, behaviour, mood and motor disability. In the safety evaluation, it was found that acupuncture combined with Madopar was associated with significantly fewer adverse effects including gastrointestinal reactions (RR=0.38, 95% CI 0.23 to 0.65, P<0.001), on-off phenomena (RR=0.27, 95% CI 0.11 to 0.66, P=0.004) and mental disorders (RR=0.24, 95% CI 0.06 to 0.92, P=0.04) but did not significantly reduce dyskinesia (RR=0.64, 95% CI 0.35 to 1.16, P=0.14). CONCLUSION: Acupuncture combined with Madopar appears, to some extent, to improve clinical effectiveness and safety in the treatment of PD, compared with Madopar alone. This conclusion must be considered cautiously, given the quality of most of the studies included was low. Therefore, more high-quality, multicentre, prospective, RCTs with large sample sizes are needed to further clarify the effect of acupuncture combined with Madopar for PD.  
  Address Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants (down)  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29180347 Approved no  
  Call Number OCOM @ refbase @ Serial 2485  
Permanent link to this record
 

 
Author Stein, D.J. url  doi
openurl 
  Title Massage Acupuncture, Moxibustion, and Other Forms of Complementary and Alternative Medicine in Inflammatory Bowel Disease Type of Study Journal Article
  Year 2017 Publication Gastroenterology Clinics of North America Abbreviated Journal Gastroenterol Clin North Am  
  Volume 46 Issue 4 Pages 875-880  
  Keywords Acupuncture; Complementary and alternative therapy; Crohn disease; Massage; Moxibustion; Ulcerative colitis  
  Abstract Complementary and alternative medicine is frequently used by inflammatory bowel disease (IBD) patients; most common are massage, acupuncture, and moxibustion therapy. Massage therapy is poorly studied in IBD patients; therefore, its benefits remain unknown. Acupuncture and moxibustion therapy have been shown to improve inflammation and symptoms in animal and human studies. However, current clinical trials of acupuncture and moxibustion are of insufficient quality to recommend them as alternative therapy. Nonetheless, because these therapies seem generally to be safe, they may have a role as complementary to conventional therapy.  
  Address Division of Gastroenterology and Hepatology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address: dstein@mcw.edu  
  Publisher
  Language English Number of Treatments  
  Treatment Follow-up Frequency Number of Participants (down)  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes PMID:29173528 Approved no  
  Call Number OCOM @ refbase @ Serial 2486  
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Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
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  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2487  
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Author Namazi, N.; Khodamoradi, K.; Larijani, B.; Ayati, M.H. url  doi
openurl 
  Title Is laser acupuncture an effective complementary therapy for obesity management? A systematic review of clinical trials Type of Study Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 452-459  
  Keywords Acupuncture Therapy/*methods; Adult; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Laser Therapy/*methods; Male; Obesity/surgery/*therapy; Obesity Management/*methods; *Weight Loss; appetite; fat accumulation; laser acupuncture; obesity  
  Abstract BACKGROUND: Complementary therapies may increase the success rate of weight loss via a calorie-restricted diet. Acupuncture is a popular complementary therapy for obesity management. To our knowledge, no studies have summarised the effects of laser acupuncture (LA) on obesity. OBJECTIVE: To evaluate the efficacy of LA, in particular with respect to its impact on anthropometric features and appetite in obese adults, by conducting a systematic review of previous clinical trials. METHODS: We searched PubMed/Medline, Scopus, Web of Science, the Cochrane Library, Embase and Google Scholar electronic databases for papers published through October 2016. All clinical trials in English containing either anthropometric indices or appetite parameters were included. Two reviewers independently examined studies based on a predefined form for data extraction and the Jadad scale for quality assessment in order to minimise bias throughout the evaluation. RESULTS: After screening the papers, seven clinical trials met the criteria and were included in the systematic review. Positive effects of LA therapy were seen in body weight (n=3), body mass index (n=5), waist circumference (n=4), hip circumference (n=3), waist to hip ratio (n=4) and % fat mass (n=3). Appetite parameters were reported in one study, which showed that LA can reduce appetite and increase the sensation of feeling full. CONCLUSION: Although some studies have indicated beneficial effects for LA on obesity, the lack of evidence with high methodological quality made it impossible to reach a definitive conclusion about the efficacy of LA for obesity management. Further high-quality, randomised, sham-controlled clinical trials with a larger sample size are needed to shed light on the efficacy of LA for obesity management and weight maintenance.  
  Address School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran  
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  Notes PMID:29074473 Approved no  
  Call Number OCOM @ refbase @ Serial 2488  
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Author Yang, X.; Liu, Y.; Liu, B.; He, L.; Liu, Z.; Yan, Y.; Liu, J.; Liu, B. url  doi
openurl 
  Title Factors related to acupuncture response in patients with chronic severe functional constipation: Secondary analysis of a randomized controlled trial Type of Study
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 11 Pages e0187723  
  Keywords *Acupuncture Therapy; Constipation/*physiopathology/*therapy; Demography; Electroacupuncture; Female; Humans; Logistic Models; Male; Middle Aged; Treatment Outcome  
  Abstract BACKGROUND: Acupuncture has been demonstrated to be effective and safe for chronic severe functional constipation (CSFC). However, which patients with CSFC will have a better response to acupuncture remains unclear. OBJECTIVE: To explore factors related to acupuncture response in patients with CSFC. METHODS: We performed a secondary analysis of a previous multicenter randomized controlled trial consisting of a 2-week run-in period, 8-week treatment, and 12-week follow-up without treatment in which patients with CSFC were randomly allocated to an electroacupuncture group or a sham electroacupuncture group. Responders were defined as participants with an increase of at least one complete spontaneous bowel movement (CSBM) in week 20 compared with the baseline period. The CSBM responder rate in both groups was described, and the baseline characteristics of participants potentially related to acupuncture response were mainly analyzed using logistic regression analysis with bootstrapping techniques. RESULTS: A total of 1021 participants were analyzed in this study, of whom 516 (50.5%) were classified as responders. The CSBM responder rate in week 20 was significantly greater in the electroacupuncture group than in the sham electroacupuncture group (62.9% vs. 37.9%, respectively; P<0.001). Both age and comorbidity were negatively associated with clinical response: with every one-year increase in age, the likelihood of clinical response was reduced by 1.2% (OR 0.988, 95%CI 0.980 to 0.996; P = 0.005), and patients with comorbidities were approximately 42% less likely to respond to treatment (OR 0.581, 95%CI 0.248 to 0.914; P = 0.001). CONCLUSION: CSFC patients with increasing age and comorbidity may be less likely to respond to acupuncture. These findings contribute to guiding clinical practice in terms of pretreatment patient selection. Further research is needed to confirm the association.  
  Address Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China  
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  Notes PMID:29166673; PMCID:PMC5699843 Approved no  
  Call Number OCOM @ refbase @ Serial 2489  
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Author Chavez, L.M.; Huang, S.-S.; MacDonald, I.; Lin, J.-G.; Lee, Y.-C.; Chen, Y.-H. url  doi
openurl 
  Title Mechanisms of Acupuncture Therapy in Ischemic Stroke Rehabilitation: A Literature Review of Basic Studies Type of Study Journal Article
  Year 2017 Publication International Journal of Molecular Sciences Abbreviated Journal Int J Mol Sci  
  Volume 18 Issue 11 Pages  
  Keywords acupuncture; basic research; cerebral ischemia; rehabilitation; stroke  
  Abstract Acupuncture is recommended by the World Health Organization (WHO) as an alternative and complementary strategy for stroke treatment and for improving stroke care. Clinical trial and meta-analysis findings have demonstrated the efficacy of acupuncture in improving balance function, reducing spasticity, and increasing muscle strength and general well-being post-stroke. The mechanisms underlying the beneficial effects of acupuncture in stroke rehabilitation remain unclear. The aim of this study was to conduct a literature review, summarize the current known mechanisms in ischemic stroke rehabilitation through acupuncture and electroacupuncture (EA) therapy, and to detail the frequently used acupoints implicated in these effects. The evidence in this review indicates that five major different mechanisms are involved in the beneficial effects of acupuncture/EA on ischemic stroke rehabilitation: (1) Promotion of neurogenesis and cell proliferation in the central nervous system (CNS); (2) Regulation of cerebral blood flow in the ischemic area; (3) Anti-apoptosis in the ischemic area; (4) Regulation of neurochemicals; and, (5) Improvement of impaired long-term potentiation (LTP) and memory after stroke. The most frequently used acupoints in basic studies include Baihui (GV20), Zusanli (ST36), Quchi (LI11), Shuigou (GV26), Dazhui (GV14), and Hegu (LI4). Our findings show that acupuncture exerts a beneficial effect on ischemic stroke through modulation of different mechanisms originating in the CNS.  
  Address Department of Photonics and Communication Engineering, Asia University, Taichung 41354, Taiwan. yihungchen@mail.cmu.edu.tw  
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  Notes PMID:29143805; PMCID:PMC5713240 Approved no  
  Call Number OCOM @ refbase @ Serial 2490  
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Author Seo, S.Y.; Lee, K.-B.; Shin, J.-S.; Lee, J.; Kim, M.-R.; Ha, I.-H.; Ko, Y.; Lee, Y.J. url  doi
openurl 
  Title Effectiveness of Acupuncture and Electroacupuncture for Chronic Neck Pain: A Systematic Review and Meta-Analysis Type of Study
  Year 2017 Publication The American Journal of Chinese Medicine Abbreviated Journal Am J Chin Med  
  Volume 45 Issue 8 Pages 1573-1595  
  Keywords *Acupuncture Therapy; Chronic Disease; Databases, Bibliographic; *Electroacupuncture; Humans; Neck Pain/*therapy; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome; Acupuncture; Effectiveness; Electroacupuncture; Meta-Analysis; Review; Safety; Systematic Review  
  Abstract The aim of this systematic review was to assess evidence from randomized controlled trials (RCTs) on the effectiveness and safety of acupuncture and electroacupuncture in patients with chronic neck pain. We searched nine databases including Chinese, Japanese and Korean databases through 30 July 2016. The participants were adults with chronic neck pain and were treated with acupuncture or electroacupuncture. Eligible trials were those with intervention groups receiving acupuncture and electroacupuncture with or without active control, and control groups receiving other conventional treatments such as physical therapy or medication. Outcomes included pain intensity, disability, quality of life (QoL) and adverse effects. For statistical pooling, the standardized mean difference (SMD) and its 95% confidence interval (CI) were calculated using a fixed-effects model. Sixteen RCTs were selected. The comparison of the sole acupuncture group and the active control group did not come out with a significant difference in pain (SMD 0.24, 95% CI [Formula: see text]0.27-0.75), disability (SMD 0.51, 95% CI [Formula: see text]0.01-1.02), or QoL (SMD [Formula: see text]0.37, 95% CI [Formula: see text]1.09-0.35), showing a similar effectiveness of acupuncture with active control. When acupuncture was added into the control group, the acupuncture add-on group showed significantly higher relief of pain in studies with unclear allocation concealment (SMD [Formula: see text]1.78, 95% CI [Formula: see text]2.08-[Formula: see text]1.48), but did not show significant relief of pain in studies with good allocation concealment (SMD [Formula: see text]0.07, 95% CI [Formula: see text]0.26-0.12). Significant relief of pain was observed when the sole electroacupuncture group was compared to the control group or electroacupuncture was added onto the active control group, but a lot of the results were evaluated to have low level of evidence, making it difficult to draw clear conclusions. In the result reporting adverse effects, no serious outcome of adverse event was confirmed. Acupuncture and conventional medicine for chronic neck pain have similar effectiveness on pain and disability when compared solely between the two of them. When acupuncture was added onto conventional treatment it relieved pain better, and electroacupuncture relieved pain even more. It is difficult to draw conclusion because the included studies have a high risk of bias and imprecision. Therefore better designed large-scale studies are needed in the future.  
  Address dagger Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul, Republic of Korea  
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  Language English Number of Treatments  
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  Time in Treatment Condition
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  Notes PMID:29121797 Approved no  
  Call Number OCOM @ refbase @ Serial 2492  
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Author Zhang, Q.; Yue, J.; Golianu, B.; Sun, Z.; Lu, Y. url  doi
openurl 
  Title Updated systematic review and meta-analysis of acupuncture for chronic knee pain Type of Study Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 392-403  
  Keywords *Acupuncture Therapy; Arthralgia/*therapy; Humans; Osteoarthritis, Knee/*therapy; Pain Management; Pain Measurement; Research Design; Treatment Outcome; acupuncture; auricular acupuncture; electroacupuncture; pain management; pain research  
  Abstract OBJECTIVE: To assess the effectiveness and safety of acupuncture for the treatment of chronic knee pain (CKP). METHODS: We searched the MEDLINE, EMBASE, Cochrane CENTERAL, CINAHL and four Chinese medical databases from their inception to June 2017. We included randomised controlled trials of acupuncture as the sole treatment or as an adjunctive treatment for CKP. The primary outcome was pain intensity measured by visual analogue scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale and 11-point numeric rating scale. Secondary outcome measurements included the 36-Item Short Form Health Survey and adverse events. The quality of all included studies was evaluated using the Cochrane risk-of-bias criteria and the STRICTA (Standards for Reporting Interventions in Controlled Trials of Acupuncture) checklist. RESULTS: Nineteen trials were included in this systematic review. Of these, data from 17 studies were available for analysis. Regarding the effectiveness of acupuncture alone or combined with other treatment, the results of the meta-analysis showed that acupuncture was associated with significantly reduced CKP at 12 weeks on WOMAC pain subscale (mean difference (MD) -1.12, 95% confidence interval (CI) -1.98 to -0.26, I(2)=62%, 3 trials, 608 participants) and VAS (MD -10.56, 95% CI -17.69 to -3.44, I(2)=0%, 2 trials, 145 patients). As for safety, no difference was found between the acupuncture and control groups (risk ratio 1.08, 95% CI 0.54 to 2.17, I(2)=29%). CONCLUSION: From this systematic review, we conclude that acupuncture may be effective at relieving CKP 12 weeks after acupuncture administration, based on the current evidence and our protocol. However, given the heterogeneity and methodological limitations of the included trials, we are currently unable to draw any strong conclusions regarding the effectiveness of acupuncture for chronic knee pain. In addition, we found that acupuncture appears to have a satisfactory safety profile, although further studies with larger numbers of participants are needed to confirm the safety of this technique. STRENGTHS: Systematic review without language restrictions. LIMITATIONS: Only a few high-quality and consistent trials could be included in this review.  
  Address Department of Biomedical Data Science, Stanford University, Stanford, California, USA  
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  Notes PMID:29117967 Approved no  
  Call Number OCOM @ refbase @ Serial 2493  
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Author Liang, Y.; Lenon, G.B.; Yang, A.W.H. url  doi
openurl 
  Title Acupressure for respiratory allergic diseases: a systematic review of randomised controlled trials Type of Study Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 413-420  
  Keywords Acupressure; Acupuncture Points; Acupuncture Therapy/*methods; Asthma/complications/*therapy; Humans; Randomized Controlled Trials as Topic; Rhinitis, Allergic/complications/*therapy; Chinese medicine; acupuncture; allergic rhinitis; asthma; hay fever  
  Abstract OBJECTIVE: To evaluate the effects and safety of acupressure for the management of respiratory allergic diseases by systematically reviewing randomised controlled trials (RCTs). METHODS: A total of 13 electronic English and Chinese databases were searched until July 2017. Two authors extracted data and evaluated risk of bias independently. Review Manager V.5.3 was employed for data analysis. RESULTS: The literature search identified 186 papers, of which only four of met the inclusion criteria: two for allergic rhinitis (AR) and two for asthma. High and unclear risk of bias existed across all the included studies. The findings demonstrated that acupressure greater effects on the relief of nasal symptoms of AR compared with 1% ephedrine nasal drop plus thermal therapy. With either Western medicine or Chinese herbal medicine as a cointervention, one study indicated that acupressure plus salbutamol was led to a significantly greater improvement of pulmonary function for patients with asthma compared with salbutamol only. However, the remaining two studies indentified no significant differences in any outcome measures between the two groups. CONCLUSIONS: No reliable conclusions regarding the effects of acupressure on AR and asthma could be drawn by this review due to the small number of available trials with significant heterogeneity of study design and high/unclear risk of bias. Further, more rigorously designed RCTs are needed. Acupressure seems safe for symptomatic relief of AR and asthma, although larger studies are required to be able to robustly confirm its safety. TRIAL REGISTRATION NUMBER: ACTRN12617001106325; Pre-results.  
  Address Discipline of Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia  
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  Notes PMID:29113981 Approved no  
  Call Number OCOM @ refbase @ Serial 2494  
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Author Liu, T.; Yu, J.-N.; Cao, B.-Y.; Peng, Y.-Y.; Chen, Y.-P.; Zhang, L. url  openurl
  Title Acupuncture for Primary Dysmenorrhea: A Meta-analysis of Randomized Controlled Trials Type of Study Journal Article
  Year 2017 Publication Alternative Therapies in Health and Medicine Abbreviated Journal Altern Ther Health Med  
  Volume Issue Pages  
  Keywords  
  Abstract Context * Primary dysmenorrhea (PD) is one of the most common complaints among young women. Acupuncture has been widely applied as a therapeutic modality in China and abroad for PD; however, the evidence for its benefits is still not convincing. Objective * The study intended to conduct a systematic review of randomized, controlled trials (RCTs) to evaluate the evidence regarding the use of acupuncture in treating PD. Design * The research team retrieved reports for RCTs published in 7 databases from their inception to March 2016, with no language restrictions: PubMed, Medline, Embase, the Cochrane Central Register of Controlled Trials, the Chinese National Knowledge Infrastructure database, the Chinese Biomedical database, and the Wanfang database. Setting * The study was conducted at the Beijing University of Traditional Chinese Medicine (Beijing, China). Participants * Participants in the reviewed studies were women aged 14 to 49 y who had received a diagnosis of PD in the absence of any visible pelvic pathology. Interventions * The types of acupuncture included traditional acupuncture, electroacupuncture, ear acupuncture, scalp acupuncture, superficial acupuncture, electrosuperficial acupuncture, wrist-ankle acupuncture, and abdominal acupuncture. Outcome Measures * The primary outcome was pain relief measured using a visual analogue scale (VAS), a verbal rating scale (VRS), or a numerical rating scale (NRS). The secondary outcomes included (1) overall improvement as measured by the short-form McGill pain questionnaire or symptom scale based on the Clinical Study Guideline for New Developed Chinese Medicine, (2) menstrual distress as measured by the Menstrual Distress Questionnaire, (3) quality of life as measured by a validated scale (eg, the short-form 36), and (4) adverse effects. Results * Twenty-three trials enrolling a total of 2770 patients were included in the review. Overall, most trials were of poor quality. Among the trials, only 6 were evaluated as having a low risk of bias, 3 of which indicated that acupuncture was statistically more effective than sham acupuncture-mean difference (MD), -3.51; 95% confidence interval (CI), -5.27 to -1.75; P < .0001; I(2), 0%-or no treatment-MD, -21.95; 95% CI, -25.45 to -18.45; P < .00001; I(2), 0%-on the VAS (0 to 100 mm). Acupuncture also showed superiority to the control arms on the VRS, the NRS, and the McGill pain questionnaire, but those findings had been influenced by methodological flaws. Conclusions * The available evidence suggests that acupuncture may be effective for PD and justifies future high-quality studies.  
  Address  
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  Notes PMID:29112942 Approved no  
  Call Number OCOM @ refbase @ Serial 2495  
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Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
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  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2498  
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Author Zhang, R.-Q.; Tan, J.; Li, F.-Y.; Ma, Y.-H.; Han, L.-X.; Yang, X.-L. url  doi
openurl 
  Title Acupuncture for the treatment of obesity in adults: a systematic review and meta-analysis Type of Study Journal Article
  Year 2017 Publication Postgraduate Medical Journal Abbreviated Journal Postgrad Med J  
  Volume 93 Issue 1106 Pages 743-751  
  Keywords Meta-analysis; Rct; acupuncture; obesity; treatment  
  Abstract OBJECTIVE: Meta-analysis was used to assess the clinical efficacy of acupuncture treatment for simple obesity and to provide evidence-based medical data for treating obesity with acupuncture. METHODS: A comprehensive search of studies on MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and Chinese databases (Wan Fang,CNKI and VIP) from 1 January 1915 through 30 November 2015 (MEDLINE search updated through 31 December 2015) was performed. We included only randomised controlled trials (RCTs) that used acupuncture and sham acupuncture to treat simple obesity. The effect of acupuncture on simple obesity was measured using body mass index (BMI), body fat mass (BFM), waist circumference (WC), hip circumference (HC), and body weight (BW). The Jadad scale was used to assess methodological quality. The random effects model was used in the pooled analysis to adjust for the heterogeneity of the included studies, and funnel plots were used to examine publication bias. The differences between treatment groups were reported as mean differences (MD). RESULTS: Eleven RCTs were selected after all relevant literature from the electronic databases had been screened. There were 338 and 305 participants in the acupuncture and sham acupuncture groups, respectively. Auricular and electro acupuncture were both able to reduce BMI in obese patients (MD 0.47 kg/m(2), 95% CI 0.35 to 0.58, p<0.001; MD 0.50 kg/m(2), 95% CI 0.38 to 0.62, p<0.001). BFM change after acupuncture treatment compared with sham treatment was statistically significant (MD 0.66 kg, 95% CI 0.51 to 0.80, p<0.001). There were also significant differences in WC and HC between the acupuncture and sham acupuncture groups (MDwc2.02 cm, 95% CI 0.21 to 3.83, p=0.03; MDHC2.74 cm, 95% CI 1.21 to 4.27, p=0.0004). BW was not statistically significantly different between the acupuncture and sham acupuncture groups (MD 0.60 kg, 95% CI -0.20 to 1.39, p=0.14). Begg's test and funnel plots showed that the potential publication bias of the included studies was very slight (p>0.05). CONCLUSION: Acupuncture for simple obesity appeared to be an effective treatment, but more studies on the safety of acupuncture used to treat simple obesity are required.  
  Address Institute of Endemic Diseases of School of Public Health, Xi'an Jiaotong University Health Science Center, Key Laboratory of Trace Elements and Endemic Diseases of the National Health and Family Planning Commission, Xi'an 710061, Shaanxi, China  
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  Notes PMID:28689171 Approved no  
  Call Number OCOM @ refbase @ Serial 2500  
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Author Yeh, M.-L.; Ko, S.-H.; Wang, M.-H.; Chi, C.-C.; Chung, Y.-C. url  doi
openurl 
  Title Acupuncture-Related Techniques for Psoriasis: A Systematic Review with Pairwise and Network Meta-Analyses of Randomized Controlled Trials Type of Study Journal Article
  Year 2017 Publication Journal of Alternative and Complementary Medicine (New York, N.Y.) Abbreviated Journal J Altern Complement Med  
  Volume 23 Issue 12 Pages 930-940  
  Keywords Acupressure/*methods; Acupuncture Points; Acupuncture Therapy/*methods; Humans; Network Meta-Analysis; Psoriasis/*therapy; Randomized Controlled Trials as Topic/statistics & numerical data; acupoint stimulation; acupressure; acupuncture; bloodletting; catgut embedding; network meta-analysis; pairwise meta-analysis; psoriasis; systematic review  
  Abstract OBJECTIVE: There has be a large body of evidence on the pharmacological treatments for psoriasis, but whether nonpharmacological interventions are effective in managing psoriasis remains largely unclear. This systematic review conducted pairwise and network meta-analyses to determine the effects of acupuncture-related techniques on acupoint stimulation for the treatment of psoriasis and to determine the order of effectiveness of these remedies. METHODS: This study searched the following databases from inception to March 15, 2016: Medline, PubMed, Cochrane Central Register of Controlled Trials, EBSCO (including Academic Search Premier, American Doctoral Dissertations, and CINAHL), Airiti Library, and China National Knowledge Infrastructure. Randomized controlled trials (RCTs) on the effects of acupuncture-related techniques on acupoint stimulation as intervention for psoriasis were independently reviewed by two researchers. RESULTS: A total of 13 RCTs with 1,060 participants were included. The methodological quality of included studies was not rigorous. Acupoint stimulation, compared with nonacupoint stimulation, had a significant treatment for psoriasis. However, the most common adverse events were thirst and dry mouth. Subgroup analysis was further done to confirm that the short-term treatment effect was superior to that of the long-term effect in treating psoriasis. Network meta-analysis identified acupressure or acupoint catgut embedding, compared with medication, and had a significant effect for improving psoriasis. It was noted that acupressure was the most effective treatment. CONCLUSIONS: Acupuncture-related techniques could be considered as an alternative or adjuvant therapy for psoriasis in short term, especially of acupressure and acupoint catgut embedding. This study recommends further well-designed, methodologically rigorous, and more head-to-head randomized trials to explore the effects of acupuncture-related techniques for treating psoriasis.  
  Address 5 Department of Nursing, Yuanpei University of Medical Technology , Hsinchu, Taiwan, Republic of China  
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  Notes PMID:28628749 Approved no  
  Call Number OCOM @ refbase @ Serial 2501  
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Author Cai, Y.; Zhang, C.S.; Liu, S.; Wen, Z.; Zhang, A.L.; Guo, X.; Lu, C.; Xue, C.C. url  doi
openurl 
  Title Electroacupuncture for Poststroke Spasticity: A Systematic Review and Meta-Analysis Type of Study Journal Article
  Year 2017 Publication Archives of Physical Medicine and Rehabilitation Abbreviated Journal Arch Phys Med Rehabil  
  Volume 98 Issue 12 Pages 2578-2589.e4  
  Keywords Electroacupuncture/*methods; Humans; Muscle Spasticity/*rehabilitation; Stroke Rehabilitation/*methods; Upper Extremity; *Acupuncture; *Meta-Analysis; *Muscle spasticity; *Rehabilitation; *Stroke  
  Abstract OBJECTIVE: To evaluate the effects and safety of electroacupuncture (EA) for stroke patients with spasticity. DATA SOURCES: Five English databases (PubMed, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine Database) and 4 Chinese databases (Chinese Biomedical Database, Chinese National Knowledge Infrastructure, Chongqing VIP Database, Wanfang Database) were searched from their inception to September 2016. STUDY SELECTION: Randomized controlled trials were included if they measured spasticity with the Modified Ashworth Scale (MAS) in stroke patients and investigated the add-on effects of electroacupuncture to routine pharmacotherapy and rehabilitation therapies. DATA EXTRACTION: Information on patients, study design, treatment details and outcomes assessing spasticity severity, motor function, and activities of daily living was extracted. DATA SYNTHESIS: In total, 22 trials involving 1425 participants met the search criteria and were included. The estimated add-on effects of EA to reduce spasticity in the upper limbs as measured by the MAS (standardized mean difference [SMD]=-.57; 95% confidence interval [CI], -.84 to -.29), and to improve overall motor function as measured by the Fugl-Meyer Assessment of Sensorimotor Recovery (mean difference [MD]=10.60; 95% CI, 8.67-12.53) were significant. Significant add-on effects of EA were also shown for spasticity in the lower limbs, lower-limb motor function, and activities of daily living ([SMD=-.88; 95% CI, -1.42 to -.35;], [MD=4.42; 95% CI, .06-8.78], and [MD=6.85; 95% CI, 3.64-10.05], respectively), although with high heterogeneity. For upper-limb motor function, no significant add-on effects of EA were found. CONCLUSIONS: EA combined with conventional routine care has the potential of reducing spasticity in the upper and lower limbs and improving overall and lower extremity motor function and activities of daily living for patients with spasticity, within 180 days poststroke. Further studies of high methodological and reporting quality are needed to confirm the effects and safety of EA, and to explore the adequate and optimal protocol of EA for poststroke spasticity, incorporating a group of comprehensive outcome measures in different populations.  
  Address China-Australia International Research Centre for Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia; Guangdong Provincial Hospital of Chinese Medicine (The Second Affiliated Hospital of Guangzhou University of Chinese Medicine), Guangdong Provincial Academy of Chinese Medical Sciences, and The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China. Electronic address: charlie.xue@rmit.edu.au  
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  Notes PMID:28455191 Approved no  
  Call Number OCOM @ refbase @ Serial 2502  
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Author Criado, M.B.; Santos, M.J.; Machado, J.; Goncalves, A.M.; Greten, H.J. url  doi
openurl 
  Title Effects of Acupuncture on Gait of Patients with Multiple Sclerosis Type of Study
  Year 2017 Publication Journal of Alternative and Complementary Medicine (New York, N.Y.) Abbreviated Journal J Altern Complement Med  
  Volume 23 Issue 11 Pages 852-857  
  Keywords *Acupuncture Therapy; Adult; Female; Gait/*physiology; Humans; Male; Middle Aged; Multiple Sclerosis/*physiopathology/*therapy; acupuncture; gait dysfunction; multiple sclerosis  
  Abstract BACKGROUND: Multiple sclerosis is considered a complex and heterogeneous disease. Approximately 85% of patients with multiple sclerosis indicate impaired gait as one of the major limitations in their daily life. Acupuncture studies found a reduction of spasticity and improvement of fatigue and imbalance in patients with multiple sclerosis, but there is a lack of studies regarding gait. DESIGN: We designed a study of acupuncture treatment, according to the Heidelberg model of Traditional Chinese Medicine (TCM), to investigate if acupuncture can be a useful therapeutic strategy in patients with gait impairment in multiple sclerosis of relapsing-remitting type. The sample consisted of 20 individuals with diagnosis of multiple sclerosis of relapsing-remitting type. Gait impairment was evaluated by the 25-foot walk test. RESULTS: The results showed differences in time to walk 25 feet following true acupuncture. In contrast, there was no difference in time to walk 25 feet following sham acupuncture. When using true acupuncture, 95% of cases showed an improvement in 25-foot walk test, compared with 45% when sham acupuncture was done. CONCLUSIONS: Our study protocol provides evidence that acupuncture treatment can be an attractive option for patients with multiple sclerosis, with gait impairment.  
  Address 4 Heidelberg School of Chinese Medicine , Heidelberg, Germany  
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  Notes PMID:28410453 Approved no  
  Call Number OCOM @ refbase @ Serial 2503  
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Author Liu, Y.-H.; Dong, G.-T.; Ye, Y.; Zheng, J.-B.; Zhang, Y.; Lin, H.-S.; Wang, X.-Q. url  doi
openurl 
  Title Effectiveness of Acupuncture for Early Recovery of Bowel Function in Cancer: A Systematic Review and Meta-Analysis Type of Study Journal Article
  Year 2017 Publication Evidence-Based Complementary and Alternative Medicine : ECAM Abbreviated Journal Evid Based Complement Alternat Med  
  Volume 2017 Issue Pages 2504021  
  Keywords  
  Abstract Objectives: The aim of this study was to evaluate the effects of acupuncture therapy to reduce the duration of postoperative ileus (POI) and to enhance bowel function in cancer patients. Methods: A systematic search of electronic databases for studies published from inception until January 2017 was carried out from six databases. Randomized controlled trials (RCTs) involving the use of acupuncture and acupressure for POI and bowel function in cancer patients were identified. Outcomes were extracted from each study and pooled to determine the risk ratio and standardized mean difference. Results: 10 RCTs involving 776 cancer patients were included. Compared with control groups (no acupuncture, sham acupuncture, and other active therapies), acupuncture was associated with shorter time to first flatus and time to first defecation. A subgroup analysis revealed that manual acupuncture was more effective on the time to first flatus and the time to first defecation; electroacupuncture was better in reducing the length of hospital stay. Compared with control groups (sham or no acupressure), acupressure was associated with shorter time to first flatus. However, GRADE approach indicated a low quality of evidence. Conclusions: Acupuncture and acupressure showed large effect size with significantly poor or inferior quality of included trials for enhancing bowel function in cancer patients after surgery. Further well-powered evidence is needed.  
  Address Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053, China  
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  Notes PMID:29422935; PMCID:PMC5750515 Approved no  
  Call Number OCOM @ refbase @ Serial 2512  
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Author Guo, T.; Chen, Z.; Tai, X.; Liu, Z.; Zhu, M. url  doi
openurl 
  Title Space-time acupuncture for intractable cough after lupus nephropathy: A case report and literature review Type of Study Journal Article
  Year 2017 Publication Medicine Abbreviated Journal Medicine (Baltimore)  
  Volume 96 Issue 51 Pages e9309  
  Keywords *Acupuncture Therapy; Chronic Disease; Cough/*therapy; Fatigue/therapy; Female; Humans; Low Back Pain/therapy; Lupus Nephritis/*complications; Middle Aged  
  Abstract RATIONALE: Some intractable chronic cough remains a common complaint for seeking medical care. Unexplained cough in lupus nephropathy patient is rare and therapeutic options are limited. PATIENT CONCERNS: A 57 year-old woman with a 7-year history of lupus nephropathy. She has suffered from chronic cough for 3 years accompanied with chronic low back pain and fatigue, as the conventional therapy cannot relieve the symptoms. DIAGNOSES: The woman is diagnosed as intractable cough after lupus nephropathy. INTERVENTIONS: 9 times space-time acupuncture (STA) treatment was performed. OUTCOMES: The cough, as well as other uncomfortable symptoms like chronic low-back pain and fatigue have resolved, and no relapse for one year follow-up. LESSONS: STA may be an effective therapy to treat intractable chronic cough.  
  Address Curie Medical School,Universityof Paris, Paris, France  
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  Notes PMID:29390501; PMCID:PMC5758203 Approved no  
  Call Number OCOM @ refbase @ Serial 2515  
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Author Yu, S.-Y.; Lv, Z.-T.; Zhang, Q.; Yang, S.; Wu, X.; Hu, Y.-P.; Zeng, F.; Liang, F.-R.; Yang, J. url  doi
openurl 
  Title Electroacupuncture is Beneficial for Primary Dysmenorrhea: The Evidence from Meta-Analysis of Randomized Controlled Trials Type of Study Journal Article
  Year 2017 Publication Evidence-Based Complementary and Alternative Medicine : ECAM Abbreviated Journal Evid Based Complement Alternat Med  
  Volume 2017 Issue Pages 1791258  
  Keywords  
  Abstract Electroacupuncture (EA) is considered to be a promising alternative therapy to relieve the menstrual pain for primary dysmenorrhea (PD), but the conclusion is controversial. Here, we conducted a systematic review and meta-analysis specifically to evaluate the clinical efficacy from randomized controlled trials (RCTs) on the use of EA in patients with PD. PubMed, Embase, ISI Web of Science, CENTRAL, CNKI, and Wanfang were searched to identify RCTs that evaluated the effectiveness of EA for PD. The outcome measurements included visual analogue scale (VAS), verbal rating scale (VRS), COX retrospective symptom scale (RSS), and the curative rate. Nine RCTs with high risk of bias were included for meta-analysis. The combined VAS 30 minutes after the completion of intervention favoured EA at SP6 when compared with EA at GB39, nonacupoints, and waiting-list groups. EA was superior to pharmacological treatment when the treatment duration lasted for three menstrual cycles, evidenced by significantly higher curative rate. No statistically significant differences between EA at SP6 and control groups were found regarding the VRS, RSS-COX1, and RSS-COX2. The findings of our study suggested that EA can provide considerable immediate analgesia effect for PD. Additional studies with rigorous design and larger sample sizes are needed.  
  Address The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China  
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  Notes PMID:29358960; PMCID:PMC5735637 Approved no  
  Call Number OCOM @ refbase @ Serial 2518  
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Author Abo Almaali, H.M.M.; Gelewkhan, A.; Mahdi, Z.A.A. url  doi
openurl 
  Title Analysis of Evidence-Based Autism Symptoms Enhancement by Acupuncture Type of Study Journal Article
  Year 2017 Publication Journal of Acupuncture and Meridian Studies Abbreviated Journal J Acupunct Meridian Stud  
  Volume 10 Issue 6 Pages 375-384  
  Keywords acupuncture; autism; clinical trials; meta-analysis  
  Abstract Autism is considered as a complex developmental disability that appears during the first two years of life. It is considered as a neurological disorder that affects brain function leading to impaired development in social interaction and communication skills. Some clinical trials demonstrated that certain acupuncture points play relatively significant role in improving both signs and symptoms of this disease. Owing to limited information available about acupuncture point's combination and protocols, the present study aimed to explore the most frequently used acupuncture points and their channels for children with autism. Thirteen articles about autism enhancement were selected from 2007 to 2015. Acupoints and their channels used in these articles were analyzed according to usage frequencies. The present study identified the following main channels that contribute to autism symptoms enhancement along with the corresponding points' frequencies: Governing Vessel channel (12), Gall bladder channel (9), Kidney channel (8), Pericardium channel (7), Extra points channel (7), Liver channel (7), Heart channel (6), Conception vessel channel (6), and Bladder channel (6). On the other hand, the frequency of each corresponding acupuncture points are EX-HN1 (5), GV-17 (4), PC-6 (4), LR-3 (3), KI-3 (3), HT-7 (3), Lu-9 (3), GV-20 (2), GV-24 (2), GV-24.5 (2), GB-13(2), GB-19 (2), KI-4 (2), LR-4 (2), ST-36 (2), SP-3 (2), SP-6 (2). In conclusion, the consensus is that both channels and points may have an important role in autism symptoms enhancement. Based on the present study, the specific channels and points selection and stimulation types need further investigation through clinical trials.  
  Address Ahl-Albait University, College of Pharmacy, Kerbala, Iraq  
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  Notes PMID:29275793 Approved no  
  Call Number OCOM @ refbase @ Serial 2521  
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Author Han, S.-Y.; Hong, Z.-Y.; Xie, Y.-H.; Zhao, Y.; Xu, X. url  doi
openurl 
  Title Therapeutic effect of Chinese herbal medicines for post stroke recovery: A traditional and network meta-analysis Type of Study
  Year 2017 Publication Medicine Abbreviated Journal Medicine (Baltimore)  
  Volume 96 Issue 49 Pages e8830  
  Keywords Adult; Aged; Aged, 80 and over; Drugs, Chinese Herbal/*therapeutic use; Female; Humans; Male; Middle Aged; Network Meta-Analysis; Phytotherapy/*methods; Randomized Controlled Trials as Topic; Stroke/*drug therapy; Stroke Rehabilitation/*methods; Treatment Outcome  
  Abstract BACKGROUND: Stroke is a condition with high morbidity and mortality, and 75% of stroke survivors lose their ability to work. Stroke is a burden to the family and society. The purpose of this study was to evaluate the effectiveness of Chinese herbal patent medicines in the treatment of patients after the acute phase of a stroke. METHODS: We searched the following databases through August 2016: PubMed, Embase, Cochrane library, China Knowledge Resource Integrated Database (CNKI), China Science Periodical Database (CSPD), and China Biology Medicine disc (CBMdisc) for studies that evaluated Chinese herbal patent medicines for post stroke recovery. A random-effect model was used to pool therapeutic effects of Chinese herbal patent medicines on stroke recovery. Network meta-analysis was used to rank the treatment for each Chinese herbal patent medicine. RESULTS: In our meta-analysis, we evaluated 28 trials that included 2780 patients. Chinese herbal patent medicines were effective in promoting recovery after stroke (OR, 3.03; 95% CI: 2.53-3.64; P < .001). Chinese herbal patent medicines significantly improved neurological function defect scores when compared with the controls (standard mean difference [SMD], -0.89; 95% CI, -1.44 to -0.35; P = .001). Chinese herbal patent medicines significantly improved the Barthel index (SMD, 0.73; 95% CI, 0.53-0.94; P < .001) and the Fugl-Meyer assessment scores (SMD, 0.60; 95% CI, 0.34-0.86; P < .001). In the network analysis, MLC601, Shuxuetong, and BuchangNaoxintong were most likely to improve stroke recovery in patients without acupuncture. Additionally, Mailuoning, Xuesaitong, BuchangNaoxintong were the patented Chinese herbal medicines most likely to improve stroke recovery when combined with acupuncture. CONCLUSIONS: Our research suggests that the Chinese herbal patent medicines were effective for stroke recovery. The most effective treatments for stroke recovery were MLC601, Shuxuetong, and BuchangNaoxintong. However, to clarify the specific effective ingredients of Chinese herbal medicines, a well-designed study is warranted.  
  Address Department of Internal Medicine, Shanghai Fengxian District Chinese Medicine Hospital, Shanghai, China  
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  Notes PMID:29245245; PMCID:PMC5728860 Approved no  
  Call Number OCOM @ refbase @ Serial 2522  
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