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Author Zhang, F.; Yu, X.; Xiao, H. url  openurl
  Title Cardioprotection of Electroacupuncture for Enhanced Recovery after Surgery on Patients Undergoing Heart Valve Replacement with Cardiopulmonary Bypass: A Randomized Control Clinical Trial Type of Study (up) Journal Article
  Year 2017 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evidence-based Complementary & Alternative Medicine (eCAM)  
  Volume Issue Pages 1-10  
  Keywords HEART valves -- Surgery; CONVALESCENCE -- Evaluation; ACUPUNCTURE points; CARDIOPULMONARY bypass; Electroacupuncture; CARDIAC surgery; REIMPLANTATION (Surgery); RANDOMIZED controlled trials  
  Abstract Copyright of Evidence-based Complementary & Alternative Medicine (eCAM) is the property of Hindawi Publishing Corporation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)  
  Address  
  Publisher Hindawi Publishing Corporation
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 121302083; Source Information: 2/16/2017, p1; Subject Term: HEART valves -- Surgery; Subject Term: CONVALESCENCE -- Evaluation; Subject Term: ACUPUNCTURE points; Subject Term: CARDIOPULMONARY bypass; Subject Term: ELECTROACUPUNCTURE; Subject Term: CARDIAC surgery; Subject Term: REIMPLANTATION (Surgery); Subject Term: RANDOMIZED controlled trials; Subject Term: ; Number of Pages: 10p; ; Illustrations: 2 Diagrams, 4 Charts, 3 Graphs; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2248  
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Author Xiao Wu; Cuihong Zheng; Xiaohu Xu; Pei Ding; Fan Xiong; Man Tian; Ying Wang; Haoxu Dong; Mingmin Zhang; Wei Wang; Shabei Xu; Minjie Xie; Guangying Huang url  openurl
  Title Electroacupuncture for Functional Constipation: A Multicenter, Randomized, Control Trial Type of Study (up) Journal Article
  Year 2017 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evidence-based Complementary & Alternative Medicine (eCAM)  
  Volume Issue Pages 1-10  
  Keywords CONSTIPATION -- Treatment; Constipation; Defecation; Electroacupuncture; GASTROINTESTINAL agents; MEDICAL cooperation; ORAL medication; PATIENT satisfaction; QUALITY of life; Research; SAMPLING (Statistics); RANDOMIZED controlled trials; TREATMENT effectiveness  
  Abstract Background and Aim. To investigate the efficacy and safety of electroacupuncture (EA) with different current intensities for functional constipation (FC) and to assess whether the effects of EA with different current intensities are superior to the mosapride. Methods. Patients with FC were randomly divided into low current intensity group (LCI), high current intensity group (HCI), and mosapride group (MC). The primary outcome was three or more spontaneous bowel movements (SBMs) per week and an increase of one or more SBMs from baseline during at least 3 of the 4 weeks. Results. The primary outcome was reached by 53.45%, 66.15%, and 52.24% of the patients who received LCI, HCI, and mosapride, respectively. EA can significantly improve the weekly SBMs and stool consistency and reduce straining severity ( p < 0.0001, all). HCI improved the quality of life better than mosapride ( p < 0.05) and reduced the proportion of severe constipation more than LCI and mosapride ( p < 0.05, both). Conclusions. EA is effective and safe at both current intensities for FC; therapeutic effects of LCI and HCI are not superior to mosapride. EA is superior to mosapride in improving patients’ life quality and satisfaction level of treatment; EA has fewer adverse events than mosapride.  
  Address  
  Publisher Hindawi Publishing Corporation
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 121086632; Source Information: 1/31/2017, p1; Subject Term: CONSTIPATION -- Treatment; Subject Term: CONSTIPATION; Subject Term: DEFECATION; Subject Term: ELECTROACUPUNCTURE; Subject Term: GASTROINTESTINAL agents; Subject Term: MEDICAL cooperation; Subject Term: ORAL medication; Subject Term: PATIENT satisfaction; Subject Term: QUALITY of life; Subject Term: RESEARCH; Subject Term: SAMPLING (Statistics); Subject Term: RANDOMIZED controlled trials; Subject Term: TREATMENT effectiveness; Subject Term: ; Number of Pages: 10p; ; Illustrations: 1 Diagram, 5 Charts, 2 Graphs; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2239  
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Author Hou, Z.; Xu, S.; Li, Q.; Cai, L.; Wu, W.; Yu, H.; Chen, H. url  openurl
  Title The Efficacy of Acupuncture for the Treatment of Cervical Vertigo: A Systematic Review and Meta-Analysis Type of Study (up) Journal Article
  Year 2017 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evidence-based Complementary & Alternative Medicine (eCAM)  
  Volume Issue Pages 1-13  
  Keywords VERTIGO treatment; Acupuncture; CEREBRAL circulation; META-analysis; SYSTEMATIC reviews (Medical research)  
  Abstract Copyright of Evidence-based Complementary & Alternative Medicine (eCAM) is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)  
  Address  
  Publisher Hindawi Limited
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 122942529; Source Information: 5/9/2017, p1; Subject Term: VERTIGO treatment; Subject Term: ACUPUNCTURE; Subject Term: CEREBRAL circulation; Subject Term: META-analysis; Subject Term: SYSTEMATIC reviews (Medical research); Subject Term: ; Number of Pages: 13p; ; Illustrations: 2 Diagrams, 11 Charts, 1 Graph; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2259  
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Author Derksen, T.M.E.; Bours, M.J.L.; Mols, F.; Weijenberg, M.P. url  openurl
  Title Lifestyle-Related Factors in the Self-Management of Chemotherapy-Induced Peripheral Neuropathy in Colorectal Cancer: A Systematic Review Type of Study (up) Journal Article
  Year 2017 Publication Evidence-based Complementary & Alternative Medicine (eCAM) Abbreviated Journal Evidence-based Complementary & Alternative Medicine (eCAM)  
  Volume Issue Pages 1-14  
  Keywords ALTERNATIVE medicine; ANTINEOPLASTIC agents; COLON tumors; DIETARY supplements; Exercise; INFORMATION storage & retrieval systems -- Medicine; Medline; PERIPHERAL neuropathy; ONLINE information services; QUALITY of life; RECTUM -- Tumors; HEALTH self-care; SYSTEMATIC reviews (Medical research); Oxaliplatin; Lifestyles  
  Abstract Background. Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect of chemotherapy treatment in colorectal cancer (CRC), negatively affecting the daily functioning and quality of life of CRC patients. Currently, there are no established treatments to prevent or reduce CIPN. The purpose of this systematic review was to identify lifestyle-related factors that can aid in preventing or reducing CIPN, as such factors may promote self-management options for CRC patients suffering from CIPN. Methods. A literature search was conducted through PubMed, Embase, and Google Scholar. Original research articles investigating oxaliplatin-related CIPN in CRC were eligible for inclusion. Results. In total, 22 articles were included, which suggested that dietary supplements, such as antioxidants and herbal extracts, as well as physical exercise and complementary therapies, such as acupuncture, may have beneficial effects on preventing or reducing CIPN symptoms. However, many of the reviewed articles presented various limitations, including small sample sizes and heterogeneity in study design and measurements of CIPN. Conclusions. No strong conclusions can be drawn regarding the role of lifestyle-related factors in the management of CIPN in CRC patients. Certain dietary supplements and physical exercise may be beneficial for the management of CIPN, but further research is warranted.  
  Address  
  Publisher Hindawi Publishing Corporation
  Language Number of Treatments  
  Treatment Follow-up Frequency Number of Participants  
  Time in Treatment Condition
  Disease Category OCSI Score  
  Notes Accession Number: 121885369; Source Information: 3/16/2017, p1; Subject Term: ALTERNATIVE medicine; Subject Term: ANTINEOPLASTIC agents; Subject Term: COLON tumors; Subject Term: DIETARY supplements; Subject Term: EXERCISE; Subject Term: INFORMATION storage & retrieval systems -- Medicine; Subject Term: MEDLINE; Subject Term: PERIPHERAL neuropathy; Subject Term: ONLINE information services; Subject Term: QUALITY of life; Subject Term: RECTUM -- Tumors; Subject Term: HEALTH self-care; Subject Term: SYSTEMATIC reviews (Medical research); Subject Term: OXALIPLATIN; Subject Term: LIFESTYLES; Subject Term: ; Number of Pages: 14p; ; Illustrations: 1 Diagram, 1 Chart; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2283  
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Author Nakamura, S.; Horiuchi, S. url  openurl
  Title Randomized Controlled Trial to Assess the Effectiveness of a Self-Care Program for Pregnant Women for Relieving Hiesho Type of Study (up) Journal Article
  Year 2017 Publication Journal of Alternative & Complementary Medicine Abbreviated Journal Journal of Alternative & Complementary Medicine  
  Volume 23 Issue 1 Pages 53-59  
  Keywords ARM -- Physiology; EXTREMITIES (Anatomy) -- Physiology; LEG -- Physiology; PREGNANCY complications -- Prevention; ACUPUNCTURE points; ANALYSIS of variance; BODY temperature; CHI-squared test; CLINICAL trials; CLOTHING & dress; CONFIDENCE intervals; EXERCISE therapy; MEDICAL thermography; PROBABILITY theory; Questionnaires; RESEARCH -- Finance; SAMPLING (Statistics); SCALE analysis (Psychology); HEALTH self-care; T-test (Statistics); WOMEN -- Health; STATISTICAL power analysis; STATISTICAL significance; SKIN temperature; RANDOMIZED controlled trials; RELATIVE risk (Medicine); PRE-tests & post-tests; DATA analysis -- Software; DESCRIPTIVE statistics; Pregnancy; Japan  
  Abstract Background A group of adults can be identified with chronic non-responding anxiety symptoms who have repeatedly accessed treatments through their GP, such as cognitive behaviour therapy, bibliotherapy and medication, but with no effect. These patients make heavy use of health service resources with no beneficial outcome. This study aims to test the effect of an acupuncture formula of three specific acupuncture points, suggested in a previous pilot study. Method 40 participants from a psychiatry waiting list were randomised into one of two groups: group 1 (n=25) received 10 weeks of acupuncture at PC6, HT7 and LR3, and group 2 was a waiting list control group. The waiting list group (n=15) then received acupuncture. Both groups were followed up for 10 weeks after treatment. The outcome measure was the State and Trait Anxiety Inventory. Results 36 patients completed the study, with two dropouts in each group. State anxiety scores in the acupuncture group decreased from 57.7 (SD 13.1) to 38.8 (12.0); scores in the waiting list control group decreased from 61.5 (11.6) to 60.6 (11.7). The difference was highly significant (p<0.0001). Similar changes were seen for trait anxiety scores. The control group showed similar statistically significant improvements when they received acupuncture. The improvements were maintained after 10 weeks of follow-up in each group. Conclusions Acupuncture is a promising intervention for patients with chronic anxiety symptoms that have proven resistant to other forms of treatment.  
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  Notes Accession Number: 120746245; Source Information: Jan2017, Vol. 23 Issue 1, p53; Subject Term: ARM -- Physiology; Subject Term: EXTREMITIES (Anatomy) -- Physiology; Subject Term: LEG -- Physiology; Subject Term: PREGNANCY complications -- Prevention; Subject Term: ACUPUNCTURE points; Subject Term: ANALYSIS of variance; Subject Term: BODY temperature; Subject Term: CHI-squared test; Subject Term: CLINICAL trials; Subject Term: CLOTHING & dress; Subject Term: CONFIDENCE intervals; Subject Term: EXERCISE therapy; Subject Term: MEDICAL thermography; Subject Term: PROBABILITY theory; Subject Term: QUESTIONNAIRES; Subject Term: RESEARCH -- Finance; Subject Term: SAMPLING (Statistics); Subject Term: SCALE analysis (Psychology); Subject Term: HEALTH self-care; Subject Term: T-test (Statistics); Subject Term: WOMEN -- Health; Subject Term: STATISTICAL power analysis; Subject Term: STATISTICAL significance; Subject Term: SKIN temperature; Subject Term: RANDOMIZED controlled trials; Subject Term: RELATIVE risk (Medicine); Subject Term: PRE-tests & post-tests; Subject Term: DATA analysis -- Software; Subject Term: DESCRIPTIVE statistics; Subject Term: PREGNANCY; Subject Term: ; Geographic Subject: JAPAN; Geographic Subject: ; Number of Pages: 7p; ; Document Type: Article; Approved no  
  Call Number OCOM @ refbase @ Serial 2288  
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Author Liu, Y.-H.; Dong, G.-T.; Ye, Y.; Zheng, J.-B.; Zhang, Y.; Lin, H.-S.; Wang, X.-Q. url  doi
openurl 
  Title Effectiveness of Acupuncture for Early Recovery of Bowel Function in Cancer: A Systematic Review and Meta-Analysis Type of Study (up) Journal Article
  Year 2017 Publication Evidence-Based Complementary and Alternative Medicine : ECAM Abbreviated Journal Evid Based Complement Alternat Med  
  Volume 2017 Issue Pages 2504021  
  Keywords  
  Abstract Objectives: The aim of this study was to evaluate the effects of acupuncture therapy to reduce the duration of postoperative ileus (POI) and to enhance bowel function in cancer patients. Methods: A systematic search of electronic databases for studies published from inception until January 2017 was carried out from six databases. Randomized controlled trials (RCTs) involving the use of acupuncture and acupressure for POI and bowel function in cancer patients were identified. Outcomes were extracted from each study and pooled to determine the risk ratio and standardized mean difference. Results: 10 RCTs involving 776 cancer patients were included. Compared with control groups (no acupuncture, sham acupuncture, and other active therapies), acupuncture was associated with shorter time to first flatus and time to first defecation. A subgroup analysis revealed that manual acupuncture was more effective on the time to first flatus and the time to first defecation; electroacupuncture was better in reducing the length of hospital stay. Compared with control groups (sham or no acupressure), acupressure was associated with shorter time to first flatus. However, GRADE approach indicated a low quality of evidence. Conclusions: Acupuncture and acupressure showed large effect size with significantly poor or inferior quality of included trials for enhancing bowel function in cancer patients after surgery. Further well-powered evidence is needed.  
  Address Department of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053, China  
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  Notes PMID:29422935; PMCID:PMC5750515 Approved no  
  Call Number OCOM @ refbase @ Serial 2430  
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Author Guo, T.; Chen, Z.; Tai, X.; Liu, Z.; Zhu, M. url  doi
openurl 
  Title Space-time acupuncture for intractable cough after lupus nephropathy: A case report and literature review Type of Study (up) Journal Article
  Year 2017 Publication Medicine Abbreviated Journal Medicine (Baltimore)  
  Volume 96 Issue 51 Pages e9309  
  Keywords *Acupuncture Therapy; Chronic Disease; Cough/*therapy; Fatigue/therapy; Female; Humans; Low Back Pain/therapy; Lupus Nephritis/*complications; Middle Aged  
  Abstract RATIONALE: Some intractable chronic cough remains a common complaint for seeking medical care. Unexplained cough in lupus nephropathy patient is rare and therapeutic options are limited. PATIENT CONCERNS: A 57 year-old woman with a 7-year history of lupus nephropathy. She has suffered from chronic cough for 3 years accompanied with chronic low back pain and fatigue, as the conventional therapy cannot relieve the symptoms. DIAGNOSES: The woman is diagnosed as intractable cough after lupus nephropathy. INTERVENTIONS: 9 times space-time acupuncture (STA) treatment was performed. OUTCOMES: The cough, as well as other uncomfortable symptoms like chronic low-back pain and fatigue have resolved, and no relapse for one year follow-up. LESSONS: STA may be an effective therapy to treat intractable chronic cough.  
  Address Curie Medical School,Universityof Paris, Paris, France  
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  Notes PMID:29390501; PMCID:PMC5758203 Approved no  
  Call Number OCOM @ refbase @ Serial 2433  
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Author Yu, S.-Y.; Lv, Z.-T.; Zhang, Q.; Yang, S.; Wu, X.; Hu, Y.-P.; Zeng, F.; Liang, F.-R.; Yang, J. url  doi
openurl 
  Title Electroacupuncture is Beneficial for Primary Dysmenorrhea: The Evidence from Meta-Analysis of Randomized Controlled Trials Type of Study (up) Journal Article
  Year 2017 Publication Evidence-Based Complementary and Alternative Medicine : ECAM Abbreviated Journal Evid Based Complement Alternat Med  
  Volume 2017 Issue Pages 1791258  
  Keywords  
  Abstract Electroacupuncture (EA) is considered to be a promising alternative therapy to relieve the menstrual pain for primary dysmenorrhea (PD), but the conclusion is controversial. Here, we conducted a systematic review and meta-analysis specifically to evaluate the clinical efficacy from randomized controlled trials (RCTs) on the use of EA in patients with PD. PubMed, Embase, ISI Web of Science, CENTRAL, CNKI, and Wanfang were searched to identify RCTs that evaluated the effectiveness of EA for PD. The outcome measurements included visual analogue scale (VAS), verbal rating scale (VRS), COX retrospective symptom scale (RSS), and the curative rate. Nine RCTs with high risk of bias were included for meta-analysis. The combined VAS 30 minutes after the completion of intervention favoured EA at SP6 when compared with EA at GB39, nonacupoints, and waiting-list groups. EA was superior to pharmacological treatment when the treatment duration lasted for three menstrual cycles, evidenced by significantly higher curative rate. No statistically significant differences between EA at SP6 and control groups were found regarding the VRS, RSS-COX1, and RSS-COX2. The findings of our study suggested that EA can provide considerable immediate analgesia effect for PD. Additional studies with rigorous design and larger sample sizes are needed.  
  Address The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China  
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  Notes PMID:29358960; PMCID:PMC5735637 Approved no  
  Call Number OCOM @ refbase @ Serial 2436  
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Author Abo Almaali, H.M.M.; Gelewkhan, A.; Mahdi, Z.A.A. url  doi
openurl 
  Title Analysis of Evidence-Based Autism Symptoms Enhancement by Acupuncture Type of Study (up) Journal Article
  Year 2017 Publication Journal of Acupuncture and Meridian Studies Abbreviated Journal J Acupunct Meridian Stud  
  Volume 10 Issue 6 Pages 375-384  
  Keywords acupuncture; autism; clinical trials; meta-analysis  
  Abstract Autism is considered as a complex developmental disability that appears during the first two years of life. It is considered as a neurological disorder that affects brain function leading to impaired development in social interaction and communication skills. Some clinical trials demonstrated that certain acupuncture points play relatively significant role in improving both signs and symptoms of this disease. Owing to limited information available about acupuncture point's combination and protocols, the present study aimed to explore the most frequently used acupuncture points and their channels for children with autism. Thirteen articles about autism enhancement were selected from 2007 to 2015. Acupoints and their channels used in these articles were analyzed according to usage frequencies. The present study identified the following main channels that contribute to autism symptoms enhancement along with the corresponding points' frequencies: Governing Vessel channel (12), Gall bladder channel (9), Kidney channel (8), Pericardium channel (7), Extra points channel (7), Liver channel (7), Heart channel (6), Conception vessel channel (6), and Bladder channel (6). On the other hand, the frequency of each corresponding acupuncture points are EX-HN1 (5), GV-17 (4), PC-6 (4), LR-3 (3), KI-3 (3), HT-7 (3), Lu-9 (3), GV-20 (2), GV-24 (2), GV-24.5 (2), GB-13(2), GB-19 (2), KI-4 (2), LR-4 (2), ST-36 (2), SP-3 (2), SP-6 (2). In conclusion, the consensus is that both channels and points may have an important role in autism symptoms enhancement. Based on the present study, the specific channels and points selection and stimulation types need further investigation through clinical trials.  
  Address Ahl-Albait University, College of Pharmacy, Kerbala, Iraq  
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  Notes PMID:29275793 Approved no  
  Call Number OCOM @ refbase @ Serial 2439  
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Author Ju, Z.Y.; Wang, K.; Cui, H.S.; Yao, Y.; Liu, S.M.; Zhou, J.; Chen, T.Y.; Xia, J. url  doi
openurl 
  Title Acupuncture for neuropathic pain in adults Type of Study (up) Journal Article
  Year 2017 Publication The Cochrane Database of Systematic Reviews Abbreviated Journal Cochrane Database Syst Rev  
  Volume 12 Issue Pages Cd012057  
  Keywords *Acupuncture Therapy; Adult; Analgesics/therapeutic use; Chronic Pain/*therapy; Drugs, Chinese Herbal/therapeutic use; Humans; Inositol/therapeutic use; Middle Aged; Neuralgia/*therapy; Nimodipine/therapeutic use; Pain Measurement; Quality of Life; Randomized Controlled Trials as Topic; Vitamin B 12/analogs & derivatives/therapeutic use  
  Abstract BACKGROUND: Neuropathic pain may be caused by nerve damage, and is often followed by changes to the central nervous system. Uncertainty remains regarding the effectiveness and safety of acupuncture treatments for neuropathic pain, despite a number of clinical trials being undertaken. OBJECTIVES: To assess the analgesic efficacy and adverse events of acupuncture treatments for chronic neuropathic pain in adults. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase, four Chinese databases, ClinicalTrials.gov and World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) on 14 February 2017. We also cross checked the reference lists of included studies. SELECTION CRITERIA: Randomised controlled trials (RCTs) with treatment duration of eight weeks or longer comparing acupuncture (either given alone or in combination with other therapies) with sham acupuncture, other active therapies, or treatment as usual, for neuropathic pain in adults. We searched for studies of acupuncture based on needle insertion and stimulation of somatic tissues for therapeutic purposes, and we excluded other methods of stimulating acupuncture points without needle insertion. We searched for studies of manual acupuncture, electroacupuncture or other acupuncture techniques used in clinical practice (such as warm needling, fire needling, etc). DATA COLLECTION AND ANALYSIS: We used the standard methodological procedures expected by Cochrane. The primary outcomes were pain intensity and pain relief. The secondary outcomes were any pain-related outcome indicating some improvement, withdrawals, participants experiencing any adverse event, serious adverse events and quality of life. For dichotomous outcomes, we calculated risk ratio (RR) with 95% confidence intervals (CI), and for continuous outcomes we calculated the mean difference (MD) with 95% CI. We also calculated number needed to treat for an additional beneficial outcome (NNTB) where possible. We combined all data using a random-effects model and assessed the quality of evidence using GRADE to generate 'Summary of findings' tables. MAIN RESULTS: We included six studies involving 462 participants with chronic peripheral neuropathic pain (442 completers (251 male), mean ages 52 to 63 years). The included studies recruited 403 participants from China and 59 from the UK. Most studies included a small sample size (fewer than 50 participants per treatment arm) and all studies were at high risk of bias for blinding of participants and personnel. Most studies had unclear risk of bias for sequence generation (four out of six studies), allocation concealment (five out of six) and selective reporting (all included studies). All studies investigated manual acupuncture, and we did not identify any study comparing acupuncture with treatment as usual, nor any study investigating other acupuncture techniques (such as electroacupuncture, warm needling, fire needling).One study compared acupuncture with sham acupuncture. We are uncertain if there is any difference between the two interventions on reducing pain intensity (n = 45; MD -0.4, 95% CI -1.83 to 1.03, very low-quality evidence), and neither group achieved 'no worse than mild pain' (visual analogue scale (VAS, 0-10) average score was 5.8 and 6.2 respectively in the acupuncture and sham acupuncture groups, where 0 = no pain). There was limited data on quality of life, which showed no clear difference between groups. Evidence was not available on pain relief, adverse events or other pre-defined secondary outcomes for this comparison.Three studies compared acupuncture alone versus other therapies (mecobalamin combined with nimodipine, and inositol). Acupuncture may reduce the risk of 'no clinical response' to pain than other therapies (n = 209; RR 0.25, 95% CI 0.12 to 0.51), however, evidence was not available for pain intensity, pain relief, adverse events or any of the other secondary outcomes.Two studies compared acupuncture combined with other active therapies (mecobalamin, and Xiaoke bitong capsule) versus other active therapies used alone. We found that the acupuncture combination group had a lower VAS score for pain intensity (n = 104; MD -1.02, 95% CI -1.09 to -0.95) and improved quality of life (n = 104; MD -2.19, 95% CI -2.39 to -1.99), than those receiving other therapy alone. However, the average VAS score of the acupuncture and control groups was 3.23 and 4.25 respectively, indicating neither group achieved 'no worse than mild pain'. Furthermore, this evidence was from a single study with high risk of bias and a very small sample size. There was no evidence on pain relief and we identified no clear differences between groups on other parameters, including 'no clinical response' to pain and withdrawals. There was no evidence on adverse events.The overall quality of evidence is very low due to study limitations (high risk of performance, detection, and attrition bias, and high risk of bias confounded by small study size) or imprecision. We have limited confidence in the effect estimate and the true effect is likely to be substantially different from the estimated effect. AUTHORS' CONCLUSIONS: Due to the limited data available, there is insufficient evidence to support or refute the use of acupuncture for neuropathic pain in general, or for any specific neuropathic pain condition when compared with sham acupuncture or other active therapies. Five studies are still ongoing and seven studies are awaiting classification due to the unclear treatment duration, and the results of these studies may influence the current findings.  
  Address College of Acumox and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, China  
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  Notes PMID:29197180 Approved no  
  Call Number OCOM @ refbase @ Serial 2442  
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Author Bridgett, R.; Klose, P.; Duffield, R.; Mydock, S.; Lauche, R. url  doi
openurl 
  Title Effects of Cupping Therapy in Amateur and Professional Athletes: Systematic Review of Randomized Controlled Trials Type of Study (up) Journal Article
  Year 2017 Publication Journal of Alternative and Complementary Medicine (New York, N.Y.) Abbreviated Journal J Altern Complement Med  
  Volume Issue Pages  
  Keywords complementary medicine; efficacy; pain; safety; traditional medicine  
  Abstract OBJECTIVE: Despite the recent re-emergence of the process of cupping by athletes, supporting evidence for its efficacy and safety remains scarce. This systematic review aims to summarize the evidence of clinical trials on cupping for athletes. METHODS: SCOPUS, Cochrane Library, PubMed, AMED, and CNKI databases were searched from their inception to December 10, 2016. Randomized controlled trials on cupping therapy with no restriction regarding the technique, or cointerventions, were included, if they measured the effects of cupping compared with any other intervention on health and performance outcomes in professionals, semi-professionals, and leisure athletes. Data extraction and risk of bias assessment using the Cochrane Risk of Bias Tool were conducted independently by two pairs of reviewers. RESULTS: Eleven trials with n = 498 participants from China, the United States, Greece, Iran, and the United Arab Emirates were included, reporting effects on different populations, including soccer, football, and handball players, swimmers, gymnasts, and track and field athletes of both amateur and professional nature. Cupping was applied between 1 and 20 times, in daily or weekly intervals, alone or in combination with, for example, acupuncture. Outcomes varied greatly from symptom intensity, recovery measures, functional measures, serum markers, and experimental outcomes. Cupping was reported as beneficial for perceptions of pain and disability, increased range of motion, and reductions in creatine kinase when compared to mostly untreated control groups. The majority of trials had an unclear or high risk of bias. None of the studies reported safety. CONCLUSIONS: No explicit recommendation for or against the use of cupping for athletes can be made. More studies are necessary for conclusive judgment on the efficacy and safety of cupping in athletes.  
  Address 4 Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), Faculty of Health, University of Technology Sydney , Sydney, NSW, Australia  
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  Notes PMID:29185802 Approved no  
  Call Number OCOM @ refbase @ Serial 2443  
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Author Liu, H.; Chen, L.; Zhang, Z.; Geng, G.; Chen, W.; Dong, H.; Chen, L.; Zhan, S.; Li, T. url  doi
openurl 
  Title Effectiveness and safety of acupuncture combined with Madopar for Parkinson's disease: a systematic review with meta-analysis Type of Study (up) Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 404-412  
  Keywords Acupuncture Therapy/*mortality; Benserazide/*therapeutic use; Combined Modality Therapy; Dopamine Agents/*therapeutic use; Drug Combinations; Humans; Levodopa/*therapeutic use; Randomized Controlled Trials as Topic; Treatment Outcome; acupuncture; complementary medicine; neurology; parkinson's disease; systematic reviews  
  Abstract OBJECTIVE: To evaluate the effectiveness and safety of acupuncture combined with Madopar for the treatment of Parkinson's disease (PD), compared to the use of Madopar alone. METHODS: A systematic search was carried out for randomised controlled trials (RCTs) of acupuncture and Madopar for the treatment of PD published between April 1995 and April 2015. The primary outcome was total effectiveness rate and secondary outcomes included Unified Parkinson's Disease Rating Scale (UPDRS) scores. Data were pooled and analysed with RevMan 5.3. Results were expressed as relative ratio (RR) with 95% confidence interval (CIs). RESULTS: Finally, 11 RCTs with 831 subjects were included. Meta-analyses showed that acupuncture combined with Madopar for the treatment of PD can significantly improve the clinical effectiveness compared with Madopar alone (RR=1.28, 95% CI 1.18 to 1.38, P<0.001). It was also found that acupuncture combined with Madopar significantly improved the UPDRS II (SMD=-1.00, 95% CI -1.71 to -0.29, P=0.006) and UPDRS I-IV total summed scores (SMD=-1.15, 95% CI -1.63 to -0.67, P<0.001) but not UPDRS I (SMD=-0.37, 95% CI -0.77 to 0.02, P=0.06), UPDRS III (SMD=-0.93, 95% CI -2.28 to 0.41, P=0.17) or UPDRS IV (SMD=-0.78, 95% CI -2.24 to 0.68, P=0.30) scores. Accordingly, acupuncture combined with Madopar appeared to have a positive effect on activities of daily life and the general condition of patients with PD, but was not better than Madopar alone for the treatment of mental activity, behaviour, mood and motor disability. In the safety evaluation, it was found that acupuncture combined with Madopar was associated with significantly fewer adverse effects including gastrointestinal reactions (RR=0.38, 95% CI 0.23 to 0.65, P<0.001), on-off phenomena (RR=0.27, 95% CI 0.11 to 0.66, P=0.004) and mental disorders (RR=0.24, 95% CI 0.06 to 0.92, P=0.04) but did not significantly reduce dyskinesia (RR=0.64, 95% CI 0.35 to 1.16, P=0.14). CONCLUSION: Acupuncture combined with Madopar appears, to some extent, to improve clinical effectiveness and safety in the treatment of PD, compared with Madopar alone. This conclusion must be considered cautiously, given the quality of most of the studies included was low. Therefore, more high-quality, multicentre, prospective, RCTs with large sample sizes are needed to further clarify the effect of acupuncture combined with Madopar for PD.  
  Address Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China  
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  Notes PMID:29180347 Approved no  
  Call Number OCOM @ refbase @ Serial 2444  
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Author Stein, D.J. url  doi
openurl 
  Title Massage Acupuncture, Moxibustion, and Other Forms of Complementary and Alternative Medicine in Inflammatory Bowel Disease Type of Study (up) Journal Article
  Year 2017 Publication Gastroenterology Clinics of North America Abbreviated Journal Gastroenterol Clin North Am  
  Volume 46 Issue 4 Pages 875-880  
  Keywords Acupuncture; Complementary and alternative therapy; Crohn disease; Massage; Moxibustion; Ulcerative colitis  
  Abstract Complementary and alternative medicine is frequently used by inflammatory bowel disease (IBD) patients; most common are massage, acupuncture, and moxibustion therapy. Massage therapy is poorly studied in IBD patients; therefore, its benefits remain unknown. Acupuncture and moxibustion therapy have been shown to improve inflammation and symptoms in animal and human studies. However, current clinical trials of acupuncture and moxibustion are of insufficient quality to recommend them as alternative therapy. Nonetheless, because these therapies seem generally to be safe, they may have a role as complementary to conventional therapy.  
  Address Division of Gastroenterology and Hepatology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address: dstein@mcw.edu  
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  Notes PMID:29173528 Approved no  
  Call Number OCOM @ refbase @ Serial 2445  
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Author Xu, Y.; Zhao, W.; Li, T.; Zhao, Y.; Bu, H.; Song, S. url  doi
openurl 
  Title Effects of acupuncture for the treatment of endometriosis-related pain: A systematic review and meta-analysis Type of Study (up) Journal Article
  Year 2017 Publication PloS one Abbreviated Journal PLoS One  
  Volume 12 Issue 10 Pages e0186616  
  Keywords *Acupuncture; Endometriosis/*complications; Female; Humans; Pain Management/*methods; Pain Measurement; Publication Bias  
  Abstract BACKGROUND: Endometriosis is a multifactorial, oestrogen-dependent, inflammatory, gynaecological condition that can result in long-lasting visceral pelvic pain and infertility. Acupuncture could be an effective treatment for endometriosis and may relieve pain. Our aim in the present study was to determine the effectiveness of acupuncture as a treatment for endometriosis-related pain. METHODS: In December 2016, six databases were searched for randomised controlled trials that determined the effectiveness of acupuncture in the treatment of endometriosis-related pain. Ultimately, 10 studies involving 589 patients were included. The main outcomes assessed were variation in pain level, variation in peripheral blood CA-125 level, and clinical effective rate. All analyses were performed using comprehensive meta-analysis statistical software. RESULTS: Of the 10 studies included, only one pilot study used a placebo control and assessed blinding; the rest used various controls (medications and herbs), which were impossible to blind. The sample sizes were small in all studies, ranging from 8 to 36 patients per arm. The mean difference (MD) in pain reduction (pre- minus post-interventional pain level-measured on a 0-10-point scale) between the acupuncture and control groups was 1.36 (95% confidence intervals [CI] = 1.01-1.72, P<0.0001). Acupuncture had a positive effect on peripheral blood CA-125 levels, as compared with the control groups (MD = 5.9, 95% CI = 1.56-10.25, P = 0.008). Similarly, the effect of acupuncture on clinical effective rate was positive, as compared with the control groups (odds ratio = 2.07; 95% CI = 1.24-3.44, P = 0.005). CONCLUSIONS: Few randomised, blinded clinical trials have addressed the efficacy of acupuncture in treating endometriosis-related pain. Nonetheless, the current literature suggests that acupuncture reduces pain and serum CA-125 levels, regardless of the control intervention used. To confirm these findings, additional, blinded studies with proper controls and adequate sample sizes are needed.  
  Address Laboratory of Anatomy, School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China  
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  Notes PMID:29077705; PMCID:PMC5659600 Approved no  
  Call Number OCOM @ refbase @ Serial 2446  
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Author Namazi, N.; Khodamoradi, K.; Larijani, B.; Ayati, M.H. url  doi
openurl 
  Title Is laser acupuncture an effective complementary therapy for obesity management? A systematic review of clinical trials Type of Study (up) Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 452-459  
  Keywords Acupuncture Therapy/*methods; Adult; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Laser Therapy/*methods; Male; Obesity/surgery/*therapy; Obesity Management/*methods; *Weight Loss; appetite; fat accumulation; laser acupuncture; obesity  
  Abstract BACKGROUND: Complementary therapies may increase the success rate of weight loss via a calorie-restricted diet. Acupuncture is a popular complementary therapy for obesity management. To our knowledge, no studies have summarised the effects of laser acupuncture (LA) on obesity. OBJECTIVE: To evaluate the efficacy of LA, in particular with respect to its impact on anthropometric features and appetite in obese adults, by conducting a systematic review of previous clinical trials. METHODS: We searched PubMed/Medline, Scopus, Web of Science, the Cochrane Library, Embase and Google Scholar electronic databases for papers published through October 2016. All clinical trials in English containing either anthropometric indices or appetite parameters were included. Two reviewers independently examined studies based on a predefined form for data extraction and the Jadad scale for quality assessment in order to minimise bias throughout the evaluation. RESULTS: After screening the papers, seven clinical trials met the criteria and were included in the systematic review. Positive effects of LA therapy were seen in body weight (n=3), body mass index (n=5), waist circumference (n=4), hip circumference (n=3), waist to hip ratio (n=4) and % fat mass (n=3). Appetite parameters were reported in one study, which showed that LA can reduce appetite and increase the sensation of feeling full. CONCLUSION: Although some studies have indicated beneficial effects for LA on obesity, the lack of evidence with high methodological quality made it impossible to reach a definitive conclusion about the efficacy of LA for obesity management. Further high-quality, randomised, sham-controlled clinical trials with a larger sample size are needed to shed light on the efficacy of LA for obesity management and weight maintenance.  
  Address School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran  
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  Notes PMID:29074473 Approved no  
  Call Number OCOM @ refbase @ Serial 2447  
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Author Chavez, L.M.; Huang, S.-S.; MacDonald, I.; Lin, J.-G.; Lee, Y.-C.; Chen, Y.-H. url  doi
openurl 
  Title Mechanisms of Acupuncture Therapy in Ischemic Stroke Rehabilitation: A Literature Review of Basic Studies Type of Study (up) Journal Article
  Year 2017 Publication International Journal of Molecular Sciences Abbreviated Journal Int J Mol Sci  
  Volume 18 Issue 11 Pages  
  Keywords acupuncture; basic research; cerebral ischemia; rehabilitation; stroke  
  Abstract Acupuncture is recommended by the World Health Organization (WHO) as an alternative and complementary strategy for stroke treatment and for improving stroke care. Clinical trial and meta-analysis findings have demonstrated the efficacy of acupuncture in improving balance function, reducing spasticity, and increasing muscle strength and general well-being post-stroke. The mechanisms underlying the beneficial effects of acupuncture in stroke rehabilitation remain unclear. The aim of this study was to conduct a literature review, summarize the current known mechanisms in ischemic stroke rehabilitation through acupuncture and electroacupuncture (EA) therapy, and to detail the frequently used acupoints implicated in these effects. The evidence in this review indicates that five major different mechanisms are involved in the beneficial effects of acupuncture/EA on ischemic stroke rehabilitation: (1) Promotion of neurogenesis and cell proliferation in the central nervous system (CNS); (2) Regulation of cerebral blood flow in the ischemic area; (3) Anti-apoptosis in the ischemic area; (4) Regulation of neurochemicals; and, (5) Improvement of impaired long-term potentiation (LTP) and memory after stroke. The most frequently used acupoints in basic studies include Baihui (GV20), Zusanli (ST36), Quchi (LI11), Shuigou (GV26), Dazhui (GV14), and Hegu (LI4). Our findings show that acupuncture exerts a beneficial effect on ischemic stroke through modulation of different mechanisms originating in the CNS.  
  Address Department of Photonics and Communication Engineering, Asia University, Taichung 41354, Taiwan. yihungchen@mail.cmu.edu.tw  
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  Notes PMID:29143805; PMCID:PMC5713240 Approved no  
  Call Number OCOM @ refbase @ Serial 2449  
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Author Zhang, Q.; Yue, J.; Golianu, B.; Sun, Z.; Lu, Y. url  doi
openurl 
  Title Updated systematic review and meta-analysis of acupuncture for chronic knee pain Type of Study (up) Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 392-403  
  Keywords *Acupuncture Therapy; Arthralgia/*therapy; Humans; Osteoarthritis, Knee/*therapy; Pain Management; Pain Measurement; Research Design; Treatment Outcome; acupuncture; auricular acupuncture; electroacupuncture; pain management; pain research  
  Abstract OBJECTIVE: To assess the effectiveness and safety of acupuncture for the treatment of chronic knee pain (CKP). METHODS: We searched the MEDLINE, EMBASE, Cochrane CENTERAL, CINAHL and four Chinese medical databases from their inception to June 2017. We included randomised controlled trials of acupuncture as the sole treatment or as an adjunctive treatment for CKP. The primary outcome was pain intensity measured by visual analogue scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale and 11-point numeric rating scale. Secondary outcome measurements included the 36-Item Short Form Health Survey and adverse events. The quality of all included studies was evaluated using the Cochrane risk-of-bias criteria and the STRICTA (Standards for Reporting Interventions in Controlled Trials of Acupuncture) checklist. RESULTS: Nineteen trials were included in this systematic review. Of these, data from 17 studies were available for analysis. Regarding the effectiveness of acupuncture alone or combined with other treatment, the results of the meta-analysis showed that acupuncture was associated with significantly reduced CKP at 12 weeks on WOMAC pain subscale (mean difference (MD) -1.12, 95% confidence interval (CI) -1.98 to -0.26, I(2)=62%, 3 trials, 608 participants) and VAS (MD -10.56, 95% CI -17.69 to -3.44, I(2)=0%, 2 trials, 145 patients). As for safety, no difference was found between the acupuncture and control groups (risk ratio 1.08, 95% CI 0.54 to 2.17, I(2)=29%). CONCLUSION: From this systematic review, we conclude that acupuncture may be effective at relieving CKP 12 weeks after acupuncture administration, based on the current evidence and our protocol. However, given the heterogeneity and methodological limitations of the included trials, we are currently unable to draw any strong conclusions regarding the effectiveness of acupuncture for chronic knee pain. In addition, we found that acupuncture appears to have a satisfactory safety profile, although further studies with larger numbers of participants are needed to confirm the safety of this technique. STRENGTHS: Systematic review without language restrictions. LIMITATIONS: Only a few high-quality and consistent trials could be included in this review.  
  Address Department of Biomedical Data Science, Stanford University, Stanford, California, USA  
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  Notes PMID:29117967 Approved no  
  Call Number OCOM @ refbase @ Serial 2452  
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Author Liang, Y.; Lenon, G.B.; Yang, A.W.H. url  doi
openurl 
  Title Acupressure for respiratory allergic diseases: a systematic review of randomised controlled trials Type of Study (up) Journal Article
  Year 2017 Publication Acupuncture in Medicine : Journal of the British Medical Acupuncture Society Abbreviated Journal Acupunct Med  
  Volume 35 Issue 6 Pages 413-420  
  Keywords Acupressure; Acupuncture Points; Acupuncture Therapy/*methods; Asthma/complications/*therapy; Humans; Randomized Controlled Trials as Topic; Rhinitis, Allergic/complications/*therapy; Chinese medicine; acupuncture; allergic rhinitis; asthma; hay fever  
  Abstract OBJECTIVE: To evaluate the effects and safety of acupressure for the management of respiratory allergic diseases by systematically reviewing randomised controlled trials (RCTs). METHODS: A total of 13 electronic English and Chinese databases were searched until July 2017. Two authors extracted data and evaluated risk of bias independently. Review Manager V.5.3 was employed for data analysis. RESULTS: The literature search identified 186 papers, of which only four of met the inclusion criteria: two for allergic rhinitis (AR) and two for asthma. High and unclear risk of bias existed across all the included studies. The findings demonstrated that acupressure greater effects on the relief of nasal symptoms of AR compared with 1% ephedrine nasal drop plus thermal therapy. With either Western medicine or Chinese herbal medicine as a cointervention, one study indicated that acupressure plus salbutamol was led to a significantly greater improvement of pulmonary function for patients with asthma compared with salbutamol only. However, the remaining two studies indentified no significant differences in any outcome measures between the two groups. CONCLUSIONS: No reliable conclusions regarding the effects of acupressure on AR and asthma could be drawn by this review due to the small number of available trials with significant heterogeneity of study design and high/unclear risk of bias. Further, more rigorously designed RCTs are needed. Acupressure seems safe for symptomatic relief of AR and asthma, although larger studies are required to be able to robustly confirm its safety. TRIAL REGISTRATION NUMBER: ACTRN12617001106325; Pre-results.  
  Address Discipline of Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia  
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  Notes PMID:29113981 Approved no  
  Call Number OCOM @ refbase @ Serial 2453  
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Author Liu, T.; Yu, J.-N.; Cao, B.-Y.; Peng, Y.-Y.; Chen, Y.-P.; Zhang, L. url  openurl
  Title Acupuncture for Primary Dysmenorrhea: A Meta-analysis of Randomized Controlled Trials Type of Study (up) Journal Article
  Year 2017 Publication Alternative Therapies in Health and Medicine Abbreviated Journal Altern Ther Health Med  
  Volume Issue Pages  
  Keywords  
  Abstract Context * Primary dysmenorrhea (PD) is one of the most common complaints among young women. Acupuncture has been widely applied as a therapeutic modality in China and abroad for PD; however, the evidence for its benefits is still not convincing. Objective * The study intended to conduct a systematic review of randomized, controlled trials (RCTs) to evaluate the evidence regarding the use of acupuncture in treating PD. Design * The research team retrieved reports for RCTs published in 7 databases from their inception to March 2016, with no language restrictions: PubMed, Medline, Embase, the Cochrane Central Register of Controlled Trials, the Chinese National Knowledge Infrastructure database, the Chinese Biomedical database, and the Wanfang database. Setting * The study was conducted at the Beijing University of Traditional Chinese Medicine (Beijing, China). Participants * Participants in the reviewed studies were women aged 14 to 49 y who had received a diagnosis of PD in the absence of any visible pelvic pathology. Interventions * The types of acupuncture included traditional acupuncture, electroacupuncture, ear acupuncture, scalp acupuncture, superficial acupuncture, electrosuperficial acupuncture, wrist-ankle acupuncture, and abdominal acupuncture. Outcome Measures * The primary outcome was pain relief measured using a visual analogue scale (VAS), a verbal rating scale (VRS), or a numerical rating scale (NRS). The secondary outcomes included (1) overall improvement as measured by the short-form McGill pain questionnaire or symptom scale based on the Clinical Study Guideline for New Developed Chinese Medicine, (2) menstrual distress as measured by the Menstrual Distress Questionnaire, (3) quality of life as measured by a validated scale (eg, the short-form 36), and (4) adverse effects. Results * Twenty-three trials enrolling a total of 2770 patients were included in the review. Overall, most trials were of poor quality. Among the trials, only 6 were evaluated as having a low risk of bias, 3 of which indicated that acupuncture was statistically more effective than sham acupuncture-mean difference (MD), -3.51; 95% confidence interval (CI), -5.27 to -1.75; P < .0001; I(2), 0%-or no treatment-MD, -21.95; 95% CI, -25.45 to -18.45; P < .00001; I(2), 0%-on the VAS (0 to 100 mm). Acupuncture also showed superiority to the control arms on the VRS, the NRS, and the McGill pain questionnaire, but those findings had been influenced by methodological flaws. Conclusions * The available evidence suggests that acupuncture may be effective for PD and justifies future high-quality studies.  
  Address  
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  Notes PMID:29112942 Approved no  
  Call Number OCOM @ refbase @ Serial 2454  
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Author Cheng, C.-S.; Chen, L.-Y.; Ning, Z.-Y.; Zhang, C.-Y.; Chen, H.; Chen, Z.; Zhu, X.-Y.; Xie, J. url  doi
openurl 
  Title Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial Type of Study (up) Journal Article
  Year 2017 Publication Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer Abbreviated Journal Support Care Cancer  
  Volume 25 Issue 12 Pages 3807-3814  
  Keywords Acupuncture Points; Acupuncture Therapy/*methods; Double-Blind Method; Fatigue/etiology/*therapy; Feasibility Studies; Female; Humans; Lung Neoplasms/pathology/*physiopathology/*therapy; Male; Middle Aged; Neoplasm Staging; Physical Therapy Modalities; Pilot Projects; Quality of Life; *Acupuncture; *Cancer-related fatigue; *Lung cancer; *Quality of life  
  Abstract BACKGROUND: Cancer-related fatigue (CRF) is a distressing symptom that is the most common unpleasant side effect experienced by lung cancer patients and is challenging for clinical care workers to manage. METHODS: We performed a randomized, double-blind, placebo-controlled pilot trial to evaluate the clinical effect of acupuncture on CRF in lung cancer patients. Twenty-eight patients presenting with CRF were randomly assigned to active acupuncture or placebo acupuncture groups to receive acupoint stimulation (LI-4, Ren-6, St-36, KI-3, and Sp-6) twice per week for 4 weeks, followed by 2 weeks of follow-up. The primary outcome was the change in intensity of CFR based on the Chinese version of the Brief Fatigue Inventory (BFI-C). As the secondary endpoint, the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS) was adopted to assess the influence of acupuncture on patients' quality of life (QOL). Adverse events and safety of treatments were monitored throughout the trial. RESULTS: Our pilot study demonstrated feasibility among patients with appropriate inclusion criteria and good compliance with acupuncture treatment. A significant reduction in the BFI-C score was observed at 2 weeks in the 14 participants who received active acupuncture compared with those receiving the placebo (P < 0.01). At week 6, symptoms further improved according to the BFI-C (P < 0.001) and the FACT-LCS (P = 0.002). There were no significant differences in the incidence of adverse events in either group (P > 0.05). CONCLUSION: Fatigue is a common symptom experienced by lung cancer patients. Acupuncture may be a safe and feasible optional method for adjunctive treatment in cancer palliative care, and appropriately powered trials are warranted to evaluate the effects of acupuncture.  
  Address Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'An Road, Shanghai, 200032, China. isable624@163.com  
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  Notes PMID:28707168 Approved no  
  Call Number OCOM @ refbase @ Serial 2457  
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