Efficacy of Acupuncture in Children with Nocturnal Enuresis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Zheng-tao Lv

Wen Song

Jing Wu

Jun Yang

Tao Wang

Cai-hua Wu

Fang Gao

Xiao-cui Yuan

Ji-hong Liu

Man Li

Evidence-based Complementary & Alternative Medicine (eCAM)

2015

Systematic Review

Enuresis, Nocturnal -- Therapy

Acupuncture

Professional Practice, Evidence-Based

Systematic Review

Meta Analysis

Alternative Therapies

Enuresis, Nocturnal -- Drug Therapy

Child, Preschool

Child

Adolescence

Young Adult

Urologic Diseases (35)

AcuTrials

Background. Nocturnal enuresis (NE) is recognized as a widespread health problem in young children and adolescents. Clinical researches about acupuncture therapy for nocturnal enuresis are increasing, while systematic reviews assessing the efficacy of acupuncture therapy are still lacking. Objective. This study aims to assess the effectiveness of acupuncture therapy for nocturnal enuresis. Materials and Methods. A comprehensive literature search of 8 databases was performed up to June 2014; randomized controlled trials which compared acupuncture therapy and placebo treatment or pharmacological therapy were identified. A metaanalysis was conducted. Results. This review included 21 RCTs and a total of 1590 subjects. The overall methodological qualities were low. The results of meta-analysis showed that acupuncture therapy was more effective for clinical efficacy when compared with placebo or pharmacological treatment. Adverse events associated with acupuncture therapy were not documented. Conclusion. Based on the findings of this study, we cautiously suggest that acupuncture therapy could improve the clinical efficacy. However, the beneficial effect of acupuncture might be overstated due to low methodological qualities. Rigorous high quality RCTs are urgently needed.

10.1155/2015/320701

Accession Number: 108824615. Language: English. Entry Date: 20170222. Revision Date: 20170222. Publication Type: journal article; meta analysis; research; systematic review; tables/charts. Journal Subset: Alternative/Complementary Therapies; Biomedical; Europe; Peer Reviewed; UK & Ireland. Special Interest: Evidence-Based Practice; Pediatric Care. Instrumentation: Jadad Scale. Grant Information: This work was supported by Grants from the National NaturalScience Foundation of China (no. 81473768; no. 81101927)and Grants from Wuhan Science and Technology Bureau no.2013060602010280.. NLM UID: 101215021.

1590 patients
21 RCTs