Efficacy of acupuncture treatment for functional dyspepsia: A systematic review and meta-analysis

Item

Title

Efficacy of acupuncture treatment for functional dyspepsia: A systematic review and meta-analysis

Author(s)

Journal Publication

Date

2015

volume

23(6)

pages

759-766

Research Type

Systematic Review

Keywords

Abstract

OBJECTIVES: The use of acupuncture treatment (AT) for functional dyspepsia is increasing, particularly in Asia. However, the efficacy of AT and its side effects have not been assessed. We performed a systematic review and meta-analysis of studies related to the effectiveness of AT for functional dyspepsia. DESIGN: This study is a systemic review and meta-analysis. Seven electronic databases, including those in the English and Chinese languages, were systematically searched for randomized controlled trials of AT for functional dyspepsia through November 2012. There were no language restrictions. SETTING: Randomized controlled trials (RCT) AT compared with placebo control or a comparative intervention were considered. The methodological qualities of the studies were evaluated using the risk of bias (ROB). Subgroups were analyzed according to the kinds of controls. MAIN OUTCOME MEASURES: The primary outcomes were symptom scores. These included visual analogue scale (VAS) and Nepean Dyspepsia Index (NDI). Secondary outcomes were the total effective rate and adverse effects. RESULTS: Twenty studies, including 1423 individual cases, were systematically reviewed. The risk of bias was high. Compared to sham AT, AT was associated with a significant positive effect in patients with functional dyspepsia (2.66, 95% CI 1.85-3.82). AT also improved symptoms for functional dyspepsia (1.18, 95% CI 1.01-2.60) compared to GI tract regulators on total effective rate. In addition, two articles produced a scale in favor of AT compared to medication (0.54, 95% CI 0.18-0.90). Two RCTs reported minimal AT-related adverse events. CONCLUSIONS: The evidence suggests that AT is effective for functional dyspepsia. However, well-planned, long-term studies are necessary to evaluate the efficacy of AT for functional dyspepsia.

doi

10.1016/j.ctim.2015.07.007

pmid

PMID:26645513

View on Pubmed

Language

English

has health condition studied

Gastrointestinal Diseases

has study population number

0

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