The Impact of Acupuncture on Neurological Recovery in Spinal Cord Injury: A Systematic Review and Meta-analysis



The Impact of Acupuncture on Neurological Recovery in Spinal Cord Injury: A Systematic Review and Meta-analysis


Journal Publication





Research Type

Systematic Review



Spinal cord injury (SCI) has become a significant social and economic burden for patients and their families. The effect of acupuncture on neurological recovery in individuals with SCI remains inconclusive despite previous studies and meta-analyses. The aim of the current study was to perform a more rigorous systematic review and quality adjusted meta-analysis of studies so that the overall impact of acupuncture on neurological recovery in SCI can be determined. Randomised controlled trials only were included and were searched for in seven databases through to August 2014. Four key outcomes were assessed: Neurological recovery, motor function, sensory function and functional recovery. Several statistical approaches were compared, models were tested for robustness using sensitivity analysis and results are presented as weighted mean difference (WMD), standardized mean difference (SMD) for continuous outcomes and relative risk (RR) for binary outcomes. The included studies' susceptibility to bias was also assessed. A total of 12 studies were included after exclusions were applied. Heterogeneity was evident among the studies included. Pooled analyses showed that acupuncture may have a beneficial effect on neurological recovery (RRs: 1.28, 95% CI: 1.12 - 1.50), motor function (WMD: 6.86, 95% CI: 0.41 - 13.31) and functional recovery (SMD: 0.88, 95% CI: 0.56 - 1.21) and all statistical approaches concurred. Sensitivity analyses suggested that the smaller studies (sample size <30), those with acute disease and studies that used varying acupuncture sessions demonstrated a larger magnitude of effect. However, studies were generally of poor quality and publication bias favouring positive studies was evident. Therefore, the benefit of acupuncture we report is by no means definitive and well-designed future studies are recommended to confirm this.




Date of Input: 6/23/2015; Date Modified: 6/30/2015; Availability: --In File--; Priority: Normal; The Third Clinical School, Zhejiang Chinese Medical University, Hanghzou, Zhejiang, China; Eng; Web:

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has health condition studied

Nervous System Diseases

has study population number


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