The short-term effects of acupuncture on patients with diabetic gastroparesis: a randomised crossover study

Guomin Li

Chengfei Huang

Xuezhu Zhang

Hui Xie

Haiyan Cheng

Yinshan Tang

Zhigang Li

Acupuncture in Medicine

2015

33(3)

204-209

Systematic Review

DIABETES -- Complications

GASTROPARESIS -- Treatment

Acupuncture

ACUPUNCTURE points

BLOOD sugar

CHI-squared test

CONFIDENCE intervals

CROSSOVER trials

GLYCOSYLATED hemoglobin

RADIOISOTOPE scanning

SAMPLING (Statistics)

Statistics

T-test (Statistics)

DATA analysis

RANDOMIZED controlled trials

VISUAL analog scale

TREATMENT effectiveness

DATA analysis -- Software

DESCRIPTIVE statistics

MANN Whitney U Test

Background Acupuncture may improve gastrointestinal symptoms in patients with various disorders, but its efficacy in diabetic gastroparesis is unclear. Objective To evaluate the short-term effects of acupuncture on gastric emptying and gastroparesis symptoms in patients with diabetic gastroparesis. Methods In a single-blind controlled crossover trial, 25 patients with diabetic gastroparesis were randomly assigned to undergo 1 week of real acupuncture (RA) treatment followed by 1 week of sham acupuncture (SA) treatment, or vice versa, with a washout of 1 month in between. Before and after each intervention, gastric retention, the Gastroparesis Cardinal Symptom Index (GCSI), fasting blood glucose (FBG) and HbA1c levels were measured. Results 21 patients completed the study. Compared with SA treatment, RA treatment was associated with significantly greater reductions in gastric retention at 2 h (-11.1±7.0%; 95% CI -13.6% to -6.2%; p<0.01) and at 4 h (-5.0 ±2.8%; 95% CI -6.0% to -0.2%; p=0.04) and in GCSI score (-8.0±3.4; 95% CI -8.4 to -2.8; p<0.01). There were no significant differences in FBG and HbA1c levels between RA and SA treatments. Conclusions In patients with diabetic gastroparesis, 1 week of short-term manual acupuncture reduces gastric retention and improves gastroparesis symptoms.

Accession Number: 103624316; Source Information: Jun2015, Vol. 33 Issue 3, p204; Subject Term: DIABETES -- Complications; Subject Term: GASTROPARESIS -- Treatment; Subject Term: ACUPUNCTURE; Subject Term: ACUPUNCTURE points; Subject Term: BLOOD sugar; Subject Term: CHI-squared test; Subject Term: CONFIDENCE intervals; Subject Term: CROSSOVER trials; Subject Term: GLYCOSYLATED hemoglobin; Subject Term: RADIOISOTOPE scanning; Subject Term: SAMPLING (Statistics); Subject Term: STATISTICS; Subject Term: T-test (Statistics); Subject Term: DATA analysis; Subject Term: RANDOMIZED controlled trials; Subject Term: VISUAL analog scale; Subject Term: TREATMENT effectiveness; Subject Term: DATA analysis -- Software; Subject Term: DESCRIPTIVE statistics; Subject Term: MANN Whitney U Test; Subject Term: ; Number of Pages: 6p; ; Document Type: Article;

0