A systematic review and meta-analysis of Baihui (GV20)-based scalp acupuncture in experimental ischemic stroke
Item
Title
A systematic review and meta-analysis of Baihui (GV20)-based scalp acupuncture in experimental ischemic stroke
Author(s)
Journal Publication
Date
2014
volume
4
pages
3981
Research Type
Systematic Review
Meta-anaylsis
Keywords
Abstract
Acupuncture for stroke has been used in China for over 2,000 years and nowadays is increasingly practiced elsewhere in the world. However, previous studies had conflicting findings on the results of acupuncture. Here, we conducted a systematic review and meta-analysis to assess the current evidence for the effect of Baihui (GV20)-based scalp acupuncture in animal models of focal cerebral ischemia. Six databases from the inception of each database up to June 2013 were electronically searched. Primary outcomes were infarct size and neurobehavioral outcome. Ultimately, 54 studies involving 1816 animals were identified describing procedures. Meta-analysis results showed that twelve studies reported significant effects of Baihui (GV20)-based scalp acupuncture for improving infarct volume compared with middle cerebral artery occlusion group (P < 0.01), and thirty-two studies reported significant effects of Baihui (GV20)-based scalp acupuncture for improving the neurological function score when compared with the control group (P < 0.01). In conclusion, Baihui (GV20)-based scalp acupuncture could improve infarct volume and neurological function score and exert potential neuroprotective role in experimental ischemic stroke.
doi
10.1038/srep03981
pmid
PMID:24496233
View on Pubmed
Language
English
has health condition studied
Stroke
has study population number
0